ASRGL1 (asparaginase and isoaspartyl peptidase 1) - Rat Genome Database

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Gene: ASRGL1 (asparaginase and isoaspartyl peptidase 1) Sus scrofa
Analyze
Symbol: ASRGL1
Name: asparaginase and isoaspartyl peptidase 1
RGD ID: 14048391
Description: ENCODES a protein that exhibits N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity (ortholog); INVOLVED IN asparagine catabolic process via L-aspartate (ortholog); PARTICIPATES IN Canavan disease pathway; ASSOCIATED WITH allergic contact dermatitis (ortholog); intellectual disability (ortholog); leukocyte adhesion deficiency 3 (ortholog); FOUND IN cytoplasm (inferred); photoreceptor inner segment (inferred); INTERACTS WITH ammonia; deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: asparaginase like 1; isoaspartyl peptidase/L-asparaginase
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl29,328,269 - 9,353,340 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.129,328,260 - 9,353,384 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.228,651,527 - 8,675,547 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
ammonia  (EXP)
deoxynivalenol  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074  


Genomics

Comparative Map Data
ASRGL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl29,328,269 - 9,353,340 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.129,328,260 - 9,353,384 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.228,651,527 - 8,675,547 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ASRGL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381162,337,448 - 62,401,431 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1162,337,448 - 62,393,412 (+)EnsemblGRCh38hg38GRCh38
GRCh371162,104,920 - 62,160,884 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361161,861,350 - 61,917,463 (+)NCBINCBI36Build 36hg18NCBI36
Build 341161,861,540 - 61,916,616NCBI
Celera1159,434,150 - 59,490,290 (+)NCBICelera
Cytogenetic Map11q12.3NCBI
HuRef1158,433,119 - 58,488,977 (+)NCBIHuRef
CHM1_11161,987,987 - 62,043,930 (+)NCBICHM1_1
T2T-CHM13v2.01162,326,729 - 62,390,808 (+)NCBIT2T-CHM13v2.0
Asrgl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39199,089,083 - 9,112,930 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl199,087,232 - 9,113,000 (-)EnsemblGRCm39 Ensembl
GRCm38199,111,719 - 9,135,566 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl199,109,868 - 9,135,636 (-)EnsemblGRCm38mm10GRCm38
MGSCv37199,186,209 - 9,210,056 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36199,178,764 - 9,202,611 (-)NCBIMGSCv36mm8
Celera198,872,234 - 8,896,083 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map196.06NCBI
Asrgl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81215,436,180 - 215,456,188 (-)NCBIGRCr8
mRatBN7.21206,006,103 - 206,027,115 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1206,006,109 - 206,027,108 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1214,424,837 - 214,444,989 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01221,450,459 - 221,470,476 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01214,139,868 - 214,159,873 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01225,309,737 - 225,329,743 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1225,309,246 - 225,329,770 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01232,247,185 - 232,267,027 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,788,145 - 211,808,943 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11211,945,611 - 211,967,379 (-)NCBI
Celera1203,517,344 - 203,537,342 (-)NCBICelera
Cytogenetic Map1q43NCBI
ASRGL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2963,569,499 - 63,620,018 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11164,612,245 - 64,662,759 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01157,700,104 - 57,750,371 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11161,056,817 - 61,107,485 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1161,056,817 - 61,107,485 (+)Ensemblpanpan1.1panPan2
ASRGL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11854,215,920 - 54,238,094 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1854,216,926 - 54,238,059 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1852,821,517 - 52,843,789 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01855,269,510 - 55,291,720 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1855,241,056 - 55,291,719 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11854,366,156 - 54,388,161 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01853,939,643 - 53,961,840 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01854,736,115 - 54,758,461 (-)NCBIUU_Cfam_GSD_1.0
Asrgl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494710,709,837 - 10,733,792 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936581821,771 - 847,704 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936581823,665 - 847,579 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ASRGL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1111,503,137 - 11,529,745 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl111,502,578 - 11,529,598 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038108,849,009 - 108,884,156 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Asrgl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249261,010,069 - 1,020,159 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249261,009,865 - 1,018,538 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ASRGL1
962 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000014281   ⟹   ENSSSCP00000013895
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl29,328,269 - 9,353,340 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000037371   ⟹   ENSSSCP00000034609
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl29,328,269 - 9,353,340 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000038499   ⟹   ENSSSCP00000047916
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl29,328,269 - 9,353,340 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000068778   ⟹   ENSSSCP00000066156
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl29,328,269 - 9,352,612 (-)Ensembl
RefSeq Acc Id: XM_003122625   ⟹   XP_003122673
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.129,328,260 - 9,353,359 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005660800   ⟹   XP_005660857
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.129,328,260 - 9,353,384 (-)NCBI
Sequence:
RefSeq Acc Id: XP_005660857   ⟸   XM_005660800
- Peptide Label: isoform X2
- UniProtKB: A0A8D1XME1 (UniProtKB/TrEMBL),   A0A8D1LIC7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003122673   ⟸   XM_003122625
- Peptide Label: isoform X1
- UniProtKB: A0A4X1VNE4 (UniProtKB/TrEMBL),   A0A8D0LSA2 (UniProtKB/TrEMBL),   A0A8D1BV88 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000066156   ⟸   ENSSSCT00000068778
Ensembl Acc Id: ENSSSCP00000034609   ⟸   ENSSSCT00000037371
Ensembl Acc Id: ENSSSCP00000013895   ⟸   ENSSSCT00000014281
Ensembl Acc Id: ENSSSCP00000047916   ⟸   ENSSSCT00000038499


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000013065 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005030172 UniProtKB/TrEMBL
  ENSSSCG00015037787 UniProtKB/TrEMBL
  ENSSSCG00025064925 UniProtKB/TrEMBL
  ENSSSCG00030004664 UniProtKB/TrEMBL
  ENSSSCG00035079075 UniProtKB/TrEMBL
  ENSSSCG00040034196 UniProtKB/TrEMBL
  ENSSSCG00045031020 UniProtKB/TrEMBL
  ENSSSCG00050015393 UniProtKB/TrEMBL
  ENSSSCG00055005342 UniProtKB/TrEMBL
  ENSSSCG00060000264 UniProtKB/TrEMBL
  ENSSSCG00065014373 UniProtKB/TrEMBL
  ENSSSCG00070025169 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000014281 ENTREZGENE
  ENSSSCT00000014281.5 UniProtKB/TrEMBL
  ENSSSCT00000037371.3 UniProtKB/TrEMBL
  ENSSSCT00000038499.2 UniProtKB/TrEMBL
  ENSSSCT00000068778.2 UniProtKB/TrEMBL
  ENSSSCT00005048079.1 UniProtKB/TrEMBL
  ENSSSCT00015050619.1 UniProtKB/TrEMBL
  ENSSSCT00025089125.1 UniProtKB/TrEMBL
  ENSSSCT00030006280.1 UniProtKB/TrEMBL
  ENSSSCT00035108060.1 UniProtKB/TrEMBL
  ENSSSCT00035108123.1 UniProtKB/TrEMBL
  ENSSSCT00035108165.1 UniProtKB/TrEMBL
  ENSSSCT00040046061.1 UniProtKB/TrEMBL
  ENSSSCT00045052985.1 UniProtKB/TrEMBL
  ENSSSCT00045053087.1 UniProtKB/TrEMBL
  ENSSSCT00050020866.1 UniProtKB/TrEMBL
  ENSSSCT00055010484.1 UniProtKB/TrEMBL
  ENSSSCT00055010510.1 UniProtKB/TrEMBL
  ENSSSCT00055010544.1 UniProtKB/TrEMBL
  ENSSSCT00055010621.1 UniProtKB/TrEMBL
  ENSSSCT00060000289.1 UniProtKB/TrEMBL
  ENSSSCT00065019128.1 UniProtKB/TrEMBL
  ENSSSCT00065019139.1 UniProtKB/TrEMBL
  ENSSSCT00070050327.1 UniProtKB/TrEMBL
  ENSSSCT00070050329.1 UniProtKB/TrEMBL
Gene3D-CATH (Glycosyl)asparaginase UniProtKB/TrEMBL
InterPro ASRGL1_meta UniProtKB/TrEMBL
  Ntn_hydrolases_N UniProtKB/TrEMBL
  Peptidase_T2 UniProtKB/TrEMBL
KEGG Report ssc:100517023 UniProtKB/TrEMBL
NCBI Gene ASRGL1 ENTREZGENE
PANTHER ISOASPARTYL PEPTIDASE/L-ASPARAGINASE UniProtKB/TrEMBL
  PTHR10188 UniProtKB/TrEMBL
Pfam Asparaginase_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF56235 UniProtKB/TrEMBL
UniProt A0A286ZT02_PIG UniProtKB/TrEMBL
  A0A287AUX9_PIG UniProtKB/TrEMBL
  A0A4X1VGM4_PIG UniProtKB/TrEMBL
  A0A4X1VNE4 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2QQ19_PIG UniProtKB/TrEMBL
  A0A8D0LSA2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1BIR0_PIG UniProtKB/TrEMBL
  A0A8D1BV88 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1ISS4_PIG UniProtKB/TrEMBL
  A0A8D1LIC7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1SKQ8_PIG UniProtKB/TrEMBL
  A0A8D1XME1 ENTREZGENE, UniProtKB/TrEMBL
  F1RPW8_PIG UniProtKB/TrEMBL
VGNC ID VGNC:85589 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-09-18 ASRGL1  asparaginase and isoaspartyl peptidase 1  ASRGL1  asparaginase like 1  Symbol and/or name change 5135510 APPROVED