ASRGL1 (asparaginase and isoaspartyl peptidase 1) - Rat Genome Database

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Gene: ASRGL1 (asparaginase and isoaspartyl peptidase 1) Pan paniscus
Analyze
Symbol: ASRGL1
Name: asparaginase and isoaspartyl peptidase 1
RGD ID: 11898356
Description: ENCODES a protein that exhibits N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity (ortholog); INVOLVED IN asparagine catabolic process via L-aspartate (ortholog); PARTICIPATES IN Canavan disease pathway; ASSOCIATED WITH allergic contact dermatitis (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN cytoplasm (inferred); photoreceptor inner segment (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: asparaginase like 1; isoaspartyl peptidase/L-asparaginase
RGD Orthologs
Human
Mouse
Rat
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2963,569,499 - 63,620,018 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11164,612,245 - 64,662,759 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01157,700,104 - 57,750,371 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11161,056,817 - 61,107,485 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1161,056,817 - 61,107,485 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ASRGL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2963,569,499 - 63,620,018 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11164,612,245 - 64,662,759 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01157,700,104 - 57,750,371 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11161,056,817 - 61,107,485 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1161,056,817 - 61,107,485 (+)Ensemblpanpan1.1panPan2
ASRGL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381162,337,448 - 62,401,431 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1162,337,448 - 62,393,412 (+)EnsemblGRCh38hg38GRCh38
GRCh371162,104,920 - 62,160,884 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361161,861,350 - 61,917,463 (+)NCBINCBI36Build 36hg18NCBI36
Build 341161,861,540 - 61,916,616NCBI
Celera1159,434,150 - 59,490,290 (+)NCBICelera
Cytogenetic Map11q12.3NCBI
HuRef1158,433,119 - 58,488,977 (+)NCBIHuRef
CHM1_11161,987,987 - 62,043,930 (+)NCBICHM1_1
T2T-CHM13v2.01162,326,729 - 62,390,808 (+)NCBIT2T-CHM13v2.0
Asrgl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39199,089,083 - 9,112,930 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl199,087,232 - 9,113,000 (-)EnsemblGRCm39 Ensembl
GRCm38199,111,719 - 9,135,566 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl199,109,868 - 9,135,636 (-)EnsemblGRCm38mm10GRCm38
MGSCv37199,186,209 - 9,210,056 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36199,178,764 - 9,202,611 (-)NCBIMGSCv36mm8
Celera198,872,234 - 8,896,083 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map196.06NCBI
Asrgl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81215,436,180 - 215,456,188 (-)NCBIGRCr8
mRatBN7.21206,006,103 - 206,027,115 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1206,006,109 - 206,027,108 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1214,424,837 - 214,444,989 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01221,450,459 - 221,470,476 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01214,139,868 - 214,159,873 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01225,309,737 - 225,329,743 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1225,309,246 - 225,329,770 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01232,247,185 - 232,267,027 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,788,145 - 211,808,943 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11211,945,611 - 211,967,379 (-)NCBI
Celera1203,517,344 - 203,537,342 (-)NCBICelera
Cytogenetic Map1q43NCBI
ASRGL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11854,215,920 - 54,238,094 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1854,216,926 - 54,238,059 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1852,821,517 - 52,843,789 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01855,269,510 - 55,291,720 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1855,241,056 - 55,291,719 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11854,366,156 - 54,388,161 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01853,939,643 - 53,961,840 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01854,736,115 - 54,758,461 (-)NCBIUU_Cfam_GSD_1.0
Asrgl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494710,709,837 - 10,733,792 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936581821,771 - 847,704 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936581823,665 - 847,579 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ASRGL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl29,328,269 - 9,353,340 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.129,328,260 - 9,353,384 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.228,651,527 - 8,675,547 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ASRGL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1111,503,137 - 11,529,745 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl111,502,578 - 11,529,598 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038108,849,009 - 108,884,156 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Asrgl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249261,010,069 - 1,020,159 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249261,009,865 - 1,018,538 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000051845   ⟹   ENSPPAP00000028997
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1161,056,817 - 61,107,485 (+)Ensembl
RefSeq Acc Id: XM_003828479   ⟹   XP_003828527
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2963,569,781 - 63,620,018 (+)NCBI
NHGRI_mPanPan11164,612,527 - 64,662,759 (+)NCBI
Mhudiblu_PPA_v01157,700,200 - 57,750,371 (+)NCBI
PanPan1.11161,056,817 - 61,107,479 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003828480   ⟹   XP_003828528
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2963,569,499 - 63,620,018 (+)NCBI
NHGRI_mPanPan11164,612,245 - 64,662,759 (+)NCBI
Mhudiblu_PPA_v01157,700,104 - 57,750,371 (+)NCBI
PanPan1.11161,056,817 - 61,107,485 (+)NCBI
Sequence:
RefSeq Acc Id: XM_055094410   ⟹   XP_054950385
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2963,569,499 - 63,618,540 (+)NCBI
NHGRI_mPanPan11164,612,245 - 64,661,286 (+)NCBI
Protein Sequences
Protein RefSeqs XP_003828527 (Get FASTA)   NCBI Sequence Viewer  
  XP_003828528 (Get FASTA)   NCBI Sequence Viewer  
  XP_054950385 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000028997.1
Reference Protein Sequences
RefSeq Acc Id: XP_003828528   ⟸   XM_003828480
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BKT4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003828527   ⟸   XM_003828479
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BKT4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000028997   ⟸   ENSPPAT00000051845
RefSeq Acc Id: XP_054950385   ⟸   XM_055094410
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000037527 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000051845.1 UniProtKB/TrEMBL
Gene3D-CATH (Glycosyl)asparaginase UniProtKB/TrEMBL
InterPro ASRGL1_meta UniProtKB/TrEMBL
  Ntn_hydrolases_N UniProtKB/TrEMBL
  Peptidase_T2 UniProtKB/TrEMBL
KEGG Report pps:100987751 UniProtKB/TrEMBL
NCBI Gene ASRGL1 ENTREZGENE
PANTHER ISOASPARTYL PEPTIDASE/L-ASPARAGINASE UniProtKB/TrEMBL
  PTHR10188 UniProtKB/TrEMBL
Pfam Asparaginase_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF56235 UniProtKB/TrEMBL
UniProt A0A2R9BKT4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-11-26 ASRGL1  asparaginase and isoaspartyl peptidase 1  ASRGL1  asparaginase like 1  Symbol and/or name change 5135510 APPROVED