ORC4 (origin recognition complex subunit 4) - Rat Genome Database

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Gene: ORC4 (origin recognition complex subunit 4) Sus scrofa
Analyze
Symbol: ORC4
Name: origin recognition complex subunit 4
RGD ID: 14013282
Description: ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); DNA binding (inferred); INVOLVED IN DNA replication (ortholog); ASSOCIATED WITH autosomal dominant intellectual developmental disorder 1 (ortholog); genetic disease (ortholog); Meier-Gorlin syndrome (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl154,096,647 - 4,171,398 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1154,096,539 - 4,176,332 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2153,748,071 - 3,824,433 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ORC4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl154,096,647 - 4,171,398 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1154,096,539 - 4,176,332 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2153,748,071 - 3,824,433 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ORC4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382147,930,396 - 148,021,551 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2147,930,396 - 148,021,604 (-)EnsemblGRCh38hg38GRCh38
GRCh372148,687,965 - 148,779,120 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362148,408,202 - 148,495,606 (-)NCBINCBI36Build 36hg18NCBI36
Build 342148,525,463 - 148,612,868NCBI
Celera2142,405,877 - 142,493,295 (-)NCBICelera
Cytogenetic Map2q23.1NCBI
HuRef2140,685,335 - 140,777,468 (-)NCBIHuRef
CHM1_12148,693,611 - 148,784,819 (-)NCBICHM1_1
T2T-CHM13v2.02148,380,848 - 148,472,005 (-)NCBIT2T-CHM13v2.0
Orc4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39248,792,836 - 48,840,287 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl248,792,836 - 48,840,289 (-)EnsemblGRCm39 Ensembl
GRCm38248,902,824 - 48,952,902 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl248,902,824 - 48,950,277 (-)EnsemblGRCm38mm10GRCm38
MGSCv37248,758,274 - 48,804,787 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36248,724,861 - 48,771,243 (-)NCBIMGSCv36mm8
Celera250,575,226 - 50,621,420 (-)NCBICelera
Cytogenetic Map2C1.1NCBI
cM Map228.42NCBI
Orc4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8353,700,046 - 53,743,293 (-)NCBIGRCr8
mRatBN7.2333,290,844 - 33,334,022 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl333,294,355 - 33,333,824 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx336,677,728 - 36,716,383 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0345,262,461 - 45,301,116 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0343,084,856 - 43,123,482 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0333,034,913 - 33,075,833 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl333,037,034 - 33,075,685 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0338,201,914 - 38,240,600 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4329,813,264 - 29,851,852 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera331,495,196 - 31,533,857 (-)NCBICelera
Cytogenetic Map3q12NCBI
Orc4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544013,932,495 - 14,006,806 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544013,933,896 - 14,006,808 (-)NCBIChiLan1.0ChiLan1.0
ORC4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21326,909,798 - 26,997,388 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B26,924,800 - 27,012,354 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B11,841,808 - 11,931,620 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B152,291,976 - 152,379,639 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B152,292,822 - 152,379,487 (-)Ensemblpanpan1.1panPan2
ORC4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11949,728,812 - 49,815,599 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1949,728,344 - 49,815,604 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1949,852,526 - 49,939,229 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01951,201,322 - 51,288,103 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1951,193,458 - 51,288,099 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11949,847,294 - 49,933,994 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01949,981,280 - 50,068,020 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01951,378,650 - 51,465,414 (-)NCBIUU_Cfam_GSD_1.0
Orc4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303112,424,304 - 112,486,767 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646929,131,789 - 29,194,863 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646929,131,892 - 29,193,258 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ORC4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11033,314,020 - 33,401,770 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1033,314,271 - 33,355,588 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040166,136,574 - 166,225,926 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Orc4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624866622,859 - 716,787 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624866626,556 - 716,725 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ORC4
2481 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003133249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005671603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005671604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005671606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013983928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021076117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021076118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021076119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021076120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021076121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021076123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002339407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002339408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK344498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU481866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FP015824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GFLN01106998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSSSCT00000017066   ⟹   ENSSSCP00000016611
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl154,104,944 - 4,171,398 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000042728   ⟹   ENSSSCP00000053259
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl154,096,647 - 4,171,271 (+)Ensembl
RefSeq Acc Id: XM_003133249   ⟹   XP_003133297
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1154,096,539 - 4,176,332 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005671603   ⟹   XP_005671660
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1154,096,593 - 4,172,827 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005671604   ⟹   XP_005671661
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1154,096,618 - 4,172,827 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005671606   ⟹   XP_005671663
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1154,096,611 - 4,172,827 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013983928   ⟹   XP_013839382
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1154,096,593 - 4,172,827 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021076117   ⟹   XP_020931776
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1154,096,609 - 4,172,827 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021076118   ⟹   XP_020931777
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1154,104,308 - 4,173,420 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021076119   ⟹   XP_020931778
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1154,096,618 - 4,172,827 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021076120   ⟹   XP_020931779
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1154,104,422 - 4,173,420 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021076121   ⟹   XP_020931780
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1154,096,611 - 4,172,827 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021076123   ⟹   XP_020931782
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1154,148,650 - 4,173,420 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002339407
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1154,096,607 - 4,176,318 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002339408
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1154,139,776 - 4,176,332 (+)NCBI
Sequence:
RefSeq Acc Id: XP_003133297   ⟸   XM_003133249
- Peptide Label: isoform X1
- UniProtKB: F1S0H7 (UniProtKB/TrEMBL),   A0A4X1TGG4 (UniProtKB/TrEMBL),   A0A8D1LQP6 (UniProtKB/TrEMBL),   A0A8D1WJX0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005671660   ⟸   XM_005671603
- Peptide Label: isoform X1
- UniProtKB: F1S0H7 (UniProtKB/TrEMBL),   A0A4X1TGG4 (UniProtKB/TrEMBL),   A0A8D1LQP6 (UniProtKB/TrEMBL),   A0A8D1WJX0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013839382   ⟸   XM_013983928
- Peptide Label: isoform X1
- UniProtKB: F1S0H7 (UniProtKB/TrEMBL),   A0A4X1TGG4 (UniProtKB/TrEMBL),   A0A8D1LQP6 (UniProtKB/TrEMBL),   A0A8D1WJX0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020931776   ⟸   XM_021076117
- Peptide Label: isoform X1
- UniProtKB: A0A4X1TGG4 (UniProtKB/TrEMBL),   F1S0H7 (UniProtKB/TrEMBL),   A0A8D1LQP6 (UniProtKB/TrEMBL),   A0A8D1WJX0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020931780   ⟸   XM_021076121
- Peptide Label: isoform X3
- UniProtKB: A0A287B9Q0 (UniProtKB/TrEMBL),   A0A8D0NFZ1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005671663   ⟸   XM_005671606
- Peptide Label: isoform X2
- UniProtKB: A0A287B9Q0 (UniProtKB/TrEMBL),   A0A4X1THM5 (UniProtKB/TrEMBL),   A0A8D0NFZ1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005671661   ⟸   XM_005671604
- Peptide Label: isoform X1
- UniProtKB: F1S0H7 (UniProtKB/TrEMBL),   A0A4X1TGG4 (UniProtKB/TrEMBL),   A0A8D1LQP6 (UniProtKB/TrEMBL),   A0A8D1WJX0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020931778   ⟸   XM_021076119
- Peptide Label: isoform X1
- UniProtKB: A0A4X1TGG4 (UniProtKB/TrEMBL),   F1S0H7 (UniProtKB/TrEMBL),   A0A8D1LQP6 (UniProtKB/TrEMBL),   A0A8D1WJX0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020931777   ⟸   XM_021076118
- Peptide Label: isoform X1
- UniProtKB: A0A4X1TGG4 (UniProtKB/TrEMBL),   F1S0H7 (UniProtKB/TrEMBL),   A0A8D1LQP6 (UniProtKB/TrEMBL),   A0A8D1WJX0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020931779   ⟸   XM_021076120
- Peptide Label: isoform X1
- UniProtKB: A0A4X1TGG4 (UniProtKB/TrEMBL),   F1S0H7 (UniProtKB/TrEMBL),   A0A8D1LQP6 (UniProtKB/TrEMBL),   A0A8D1WJX0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020931782   ⟸   XM_021076123
- Peptide Label: isoform X3
- UniProtKB: A0A287B9Q0 (UniProtKB/TrEMBL),   A0A8D0NFZ1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000053259   ⟸   ENSSSCT00000042728
Ensembl Acc Id: ENSSSCP00000016611   ⟸   ENSSSCT00000017066
Protein Domains
AAA+ ATPase   ATPase AAA-type core   Origin recognition complex subunit 4 C-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000015668 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005012412 UniProtKB/TrEMBL
  ENSSSCG00015030118 UniProtKB/TrEMBL
  ENSSSCG00025058223 UniProtKB/TrEMBL
  ENSSSCG00035069895 UniProtKB/TrEMBL
  ENSSSCG00045011201 UniProtKB/TrEMBL
  ENSSSCG00050021739 UniProtKB/TrEMBL
  ENSSSCG00060067030 UniProtKB/TrEMBL
  ENSSSCG00065048318 UniProtKB/TrEMBL
  ENSSSCG00070008934 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000017066 ENTREZGENE
  ENSSSCT00000017066.5 UniProtKB/TrEMBL
  ENSSSCT00000042728 ENTREZGENE
  ENSSSCT00000042728.3 UniProtKB/TrEMBL
  ENSSSCT00005019908.1 UniProtKB/TrEMBL
  ENSSSCT00005019942.1 UniProtKB/TrEMBL
  ENSSSCT00015039964.1 UniProtKB/TrEMBL
  ENSSSCT00015040117.1 UniProtKB/TrEMBL
  ENSSSCT00025079723.1 UniProtKB/TrEMBL
  ENSSSCT00035094424.1 UniProtKB/TrEMBL
  ENSSSCT00035094461.1 UniProtKB/TrEMBL
  ENSSSCT00045019027.1 UniProtKB/TrEMBL
  ENSSSCT00050029318.1 UniProtKB/TrEMBL
  ENSSSCT00050029362.1 UniProtKB/TrEMBL
  ENSSSCT00060091506.1 UniProtKB/TrEMBL
  ENSSSCT00060091548.1 UniProtKB/TrEMBL
  ENSSSCT00065066198.1 UniProtKB/TrEMBL
  ENSSSCT00065066204.1 UniProtKB/TrEMBL
  ENSSSCT00070017340.1 UniProtKB/TrEMBL
  ENSSSCT00070017354.1 UniProtKB/TrEMBL
  ENSSSCT00070017362.1 UniProtKB/TrEMBL
  ENSSSCT00070017368.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  AAA_16 UniProtKB/TrEMBL
  ATPase_AAA_core UniProtKB/TrEMBL
  ORC4 UniProtKB/TrEMBL
  ORC4_C UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report ssc:100519056 UniProtKB/TrEMBL
NCBI Gene ORC4 ENTREZGENE
PANTHER ORIGIN RECOGNITION COMPLEX SUBUNIT 4 UniProtKB/TrEMBL
  PTHR12087 UniProtKB/TrEMBL
Pfam AAA UniProtKB/TrEMBL
  AAA_16 UniProtKB/TrEMBL
  ORC4_C UniProtKB/TrEMBL
PIRSF ORC4 UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A287B9Q0 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TGG4 ENTREZGENE
  A0A4X1THM5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0NFZ1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1LQP6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1WJX0 ENTREZGENE, UniProtKB/TrEMBL
  F1S0H7 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A4X1TGG4 UniProtKB/TrEMBL
VGNC ID VGNC:96465 ENTREZGENE