STAM (signal transducing adaptor molecule) - Rat Genome Database

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Gene: STAM (signal transducing adaptor molecule) Sus scrofa
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Symbol: STAM
Name: signal transducing adaptor molecule
RGD ID: 13955051
Description: ENCODES a protein that exhibits phosphatidylinositol binding (inferred); ubiquitin binding (inferred); ubiquitin-like protein ligase binding (inferred); INVOLVED IN positive regulation of exosomal secretion (inferred); protein transport (inferred); regulation of extracellular exosome assembly (inferred); PARTICIPATES IN interleukin-2 signaling pathway; ASSOCIATED WITH hypoparathyroidism-deafness-renal disease syndrome (ortholog); Imerslund-Grasbeck Syndrome (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); early endosome membrane (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: signal transducing adapter molecule 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1043,947,011 - 44,016,056 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11043,946,990 - 44,016,064 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21048,632,911 - 48,699,716 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
STAM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1043,947,011 - 44,016,056 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11043,946,990 - 44,016,064 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21048,632,911 - 48,699,716 (+)NCBISscrofa10.2Sscrofa10.2susScr3
STAM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381017,644,151 - 17,716,824 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1017,644,151 - 17,716,824 (+)EnsemblGRCh38hg38GRCh38
GRCh371017,686,150 - 17,758,823 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361017,726,130 - 17,797,913 (+)NCBINCBI36Build 36hg18NCBI36
Build 341017,726,129 - 17,797,913NCBI
Celera1017,619,602 - 17,691,384 (+)NCBICelera
Cytogenetic Map10p12.33NCBI
HuRef1017,598,859 - 17,671,557 (+)NCBIHuRef
CHM1_11017,686,508 - 17,759,210 (+)NCBICHM1_1
T2T-CHM13v2.01017,662,652 - 17,736,129 (+)NCBIT2T-CHM13v2.0
Stam
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39214,078,912 - 14,152,351 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl214,078,909 - 14,154,445 (+)EnsemblGRCm39 Ensembl
GRCm38214,073,962 - 14,148,338 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl214,074,098 - 14,149,634 (+)EnsemblGRCm38mm10GRCm38
MGSCv37213,995,739 - 14,069,965 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36213,991,866 - 14,066,092 (+)NCBIMGSCv36mm8
Celera213,978,783 - 14,051,519 (+)NCBICelera
Cytogenetic Map2A2NCBI
cM Map210.36NCBI
Stam
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81782,028,779 - 82,074,717 (+)NCBIGRCr8
mRatBN7.21777,120,235 - 77,166,173 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1777,120,158 - 77,166,467 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1780,570,551 - 80,615,048 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01784,405,965 - 84,450,462 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01778,453,865 - 78,498,362 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01781,209,795 - 81,256,111 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1781,209,867 - 81,255,808 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01782,954,327 - 83,002,657 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41788,276,082 - 88,321,955 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1776,453,145 - 76,499,077 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
Stam
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542910,306,957 - 10,366,081 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542910,306,957 - 10,366,072 (-)NCBIChiLan1.0ChiLan1.0
STAM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2830,485,153 - 30,561,119 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11030,492,656 - 30,566,440 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01017,962,759 - 18,035,654 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11018,232,548 - 18,305,169 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1018,232,548 - 18,305,197 (+)Ensemblpanpan1.1panPan2
STAM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1219,264,392 - 19,344,187 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl219,266,055 - 19,344,045 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha216,365,991 - 16,445,808 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0219,553,884 - 19,634,156 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl219,553,652 - 19,652,382 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1216,756,688 - 16,836,708 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0217,592,245 - 17,672,295 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0218,212,306 - 18,292,067 (-)NCBIUU_Cfam_GSD_1.0
Stam
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934418,270,841 - 18,333,310 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365209,624,628 - 9,689,686 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365209,627,674 - 9,689,658 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STAM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1917,590,252 - 17,662,278 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl917,590,268 - 17,663,986 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605123,235,162 - 23,320,904 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Stam
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479610,201,518 - 10,269,311 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479610,195,897 - 10,269,311 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in STAM
2803 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000012079   ⟹   ENSSSCP00000011771
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1043,947,011 - 44,016,056 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000028575   ⟹   ENSSSCP00000021003
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1043,947,063 - 44,016,058 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000076904   ⟹   ENSSSCP00000069037
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1043,947,047 - 44,016,056 (+)Ensembl
RefSeq Acc Id: XM_021064813   ⟹   XP_020920472
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11043,946,990 - 44,016,064 (+)NCBI
Sequence:
RefSeq Acc Id: XP_020920472   ⟸   XM_021064813
- UniProtKB: A0A480Y3T3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000011771   ⟸   ENSSSCT00000012079
Ensembl Acc Id: ENSSSCP00000069037   ⟸   ENSSSCT00000076904
Ensembl Acc Id: ENSSSCP00000021003   ⟸   ENSSSCT00000028575
Protein Domains
SH3   VHS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000011036 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025026859 UniProtKB/TrEMBL
  ENSSSCG00030013568 UniProtKB/TrEMBL
  ENSSSCG00035014195 UniProtKB/TrEMBL
  ENSSSCG00040025940 UniProtKB/TrEMBL
  ENSSSCG00045027770 UniProtKB/TrEMBL
  ENSSSCG00050061169 UniProtKB/TrEMBL
  ENSSSCG00055011040 UniProtKB/TrEMBL
  ENSSSCG00060039622 UniProtKB/TrEMBL
  ENSSSCG00065004348 UniProtKB/TrEMBL
  ENSSSCG00070015734 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000012079 ENTREZGENE
  ENSSSCT00000012079.5 UniProtKB/TrEMBL
  ENSSSCT00000076904.2 UniProtKB/TrEMBL
  ENSSSCT00025036359.1 UniProtKB/TrEMBL
  ENSSSCT00025036540.1 UniProtKB/TrEMBL
  ENSSSCT00030018609.1 UniProtKB/TrEMBL
  ENSSSCT00035017978.1 UniProtKB/TrEMBL
  ENSSSCT00035017981.1 UniProtKB/TrEMBL
  ENSSSCT00035017983.1 UniProtKB/TrEMBL
  ENSSSCT00040034661.1 UniProtKB/TrEMBL
  ENSSSCT00040034731.1 UniProtKB/TrEMBL
  ENSSSCT00045047772.1 UniProtKB/TrEMBL
  ENSSSCT00045047989.1 UniProtKB/TrEMBL
  ENSSSCT00050083382.1 UniProtKB/TrEMBL
  ENSSSCT00055021657.1 UniProtKB/TrEMBL
  ENSSSCT00055021742.1 UniProtKB/TrEMBL
  ENSSSCT00060053631.1 UniProtKB/TrEMBL
  ENSSSCT00065005964.1 UniProtKB/TrEMBL
  ENSSSCT00070030956.1 UniProtKB/TrEMBL
  ENSSSCT00070030971.1 UniProtKB/TrEMBL
  ENSSSCT00070030982.1 UniProtKB/TrEMBL
  ENSSSCT00070030990.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.1940 UniProtKB/TrEMBL
  1.25.40.90 UniProtKB/TrEMBL
  6.10.140.100 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro ENTH_VHS UniProtKB/TrEMBL
  GAT_STAM1 UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
  STAM UniProtKB/TrEMBL
  STAM1_SH3 UniProtKB/TrEMBL
  UIM_dom UniProtKB/TrEMBL
  VHS_dom UniProtKB/TrEMBL
  VHS_STAM1 UniProtKB/TrEMBL
NCBI Gene STAM ENTREZGENE
PANTHER JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE UniProtKB/TrEMBL
  SIGNAL TRANSDUCING ADAPTER MOLECULE 1 UniProtKB/TrEMBL
Pfam SH3_1 UniProtKB/TrEMBL
  UIM UniProtKB/TrEMBL
  VHS UniProtKB/TrEMBL
PRINTS P67PHOX UniProtKB/TrEMBL
  SH3DOMAIN UniProtKB/TrEMBL
PROSITE SH3 UniProtKB/TrEMBL
  UIM UniProtKB/TrEMBL
  VHS UniProtKB/TrEMBL
SMART SH3 UniProtKB/TrEMBL
  VHS UniProtKB/TrEMBL
Superfamily-SCOP SSF48464 UniProtKB/TrEMBL
  SSF50044 UniProtKB/TrEMBL
UniProt A0A480Y3T3 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1UC12_PIG UniProtKB/TrEMBL
  A0A4X1UC33_PIG UniProtKB/TrEMBL
  A0A4X1UD74_PIG UniProtKB/TrEMBL
  A0A5G2RE13_PIG UniProtKB/TrEMBL
  A0A8D0RF70_PIG UniProtKB/TrEMBL
  A0A8D0YVS6_PIG UniProtKB/TrEMBL
  A0A8D0YVY0_PIG UniProtKB/TrEMBL
  A0A8D1DYC4_PIG UniProtKB/TrEMBL
  F1RWA6_PIG UniProtKB/TrEMBL
VGNC ID VGNC:95520 ENTREZGENE