Timm8a1 (translocase of inner mitochondrial membrane 8A1) - Rat Genome Database

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Gene: Timm8a1 (translocase of inner mitochondrial membrane 8A1) Rattus norvegicus
Analyze
Symbol: Timm8a1
Name: translocase of inner mitochondrial membrane 8A1
RGD ID: 621801
Description: Enables zinc ion binding activity. Involved in protein targeting to mitochondrion. Predicted to be located in mitochondrial intermembrane space. Predicted to be part of mitochondrial intermembrane space protein transporter complex. Human ortholog(s) of this gene implicated in deafness-dystonia-optic neuronopathy syndrome and dystonia. Orthologous to human TIMM8A (translocase of inner mitochondrial membrane 8A); PARTICIPATES IN beta-barrel pathway of mitochondrial protein import; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DDP; Ddp1; deafness dystonia protein 1 homolog; MGC72748; mitochondrial import inner membrane translocase subunit Tim8 A; Timm8a; translocase of inner mitochondrial membrane 8 (yeast) homolog A; translocase of inner mitochondrial membrane 8 homolog a; translocase of inner mitochondrial membrane 8 homolog a (yeast); translocase of inner mitochondrial membrane 8 homolog A1; translocase of inner mitochondrial membrane 8 homolog A1 (yeast)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X102,011,206 - 102,015,444 (-)NCBIGRCr8
mRatBN7.2X97,717,932 - 97,722,170 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX97,717,920 - 97,721,960 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX99,392,144 - 99,396,386 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X102,902,887 - 102,907,120 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X100,405,310 - 100,409,550 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X105,351,714 - 105,355,722 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX105,352,402 - 105,355,716 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X105,241,128 - 105,245,441 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X121,993,810 - 121,997,685 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X122,067,242 - 122,071,118 (-)NCBI
CeleraX98,758,800 - 98,762,786 (-)NCBICelera
Cytogenetic MapXq32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
2-palmitoylglycerol  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
acetamide  (EXP)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
clofibric acid  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
cypermethrin  (ISO)
dibutyl phthalate  (EXP,ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
epoxiconazole  (ISO)
fenthion  (ISO)
finasteride  (EXP)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (EXP,ISO)
FR900359  (ISO)
genistein  (EXP)
gentamycin  (EXP)
glafenine  (EXP)
inulin  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
leflunomide  (ISO)
methidathion  (ISO)
methyl methanesulfonate  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (EXP)
nefazodone  (EXP)
nimesulide  (EXP)
oxaliplatin  (EXP)
oxycodone  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phorone  (EXP)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
quinolin-8-ol  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Otopathology in Mohr-Tranebjaerg syndrome. Bahmad F, etal., Laryngoscope. 2007 Jul;117(7):1202-8.
2. Interaction of the deafness-dystonia protein DDP/TIMM8a with the signal transduction adaptor molecule STAM1. Blackstone C, etal., Biochem Biophys Res Commun 2003 May 30;305(2):345-52.
3. A novel intronic mutation in the DDP1 gene in a family with X-linked dystonia-deafness syndrome. Ezquerra M, etal., Arch Neurol. 2005 Feb;62(2):306-8.
4. Assembly of beta-barrel proteins in the mitochondrial outer membrane. Hohr AI, etal., Biochim Biophys Acta. 2015 Jan;1853(1):74-88. doi: 10.1016/j.bbamcr.2014.10.006. Epub 2014 Oct 8.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. A novel deafness/dystonia peptide gene mutation that causes dystonia in female carriers of Mohr-Tranebjaerg syndrome. Swerdlow RH and Wooten GF, Ann Neurol. 2001 Oct;50(4):537-40.
12. A family with X-linked dystonia-deafness syndrome with a novel mutation of the DDP gene. Ujike H, etal., Arch Neurol. 2001 Jun;58(6):1004-7.
Additional References at PubMed
PMID:10611480   PMID:12477932   PMID:14651853   PMID:14726512   PMID:15489334   PMID:18614015   PMID:20833797  


Genomics

Comparative Map Data
Timm8a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X102,011,206 - 102,015,444 (-)NCBIGRCr8
mRatBN7.2X97,717,932 - 97,722,170 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX97,717,920 - 97,721,960 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX99,392,144 - 99,396,386 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X102,902,887 - 102,907,120 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X100,405,310 - 100,409,550 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X105,351,714 - 105,355,722 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX105,352,402 - 105,355,716 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X105,241,128 - 105,245,441 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X121,993,810 - 121,997,685 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X122,067,242 - 122,071,118 (-)NCBI
CeleraX98,758,800 - 98,762,786 (-)NCBICelera
Cytogenetic MapXq32NCBI
TIMM8A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X101,345,661 - 101,348,742 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX101,345,661 - 101,348,742 (-)EnsemblGRCh38hg38GRCh38
GRCh37X100,600,649 - 100,603,730 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X100,487,306 - 100,490,343 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X100,406,794 - 100,409,832NCBI
CeleraX101,120,103 - 101,123,416 (-)NCBICelera
Cytogenetic MapXq22.1NCBI
HuRefX90,406,792 - 90,410,105 (-)NCBIHuRef
CHM1_1X100,494,127 - 100,497,440 (-)NCBICHM1_1
T2T-CHM13v2.0X99,789,782 - 99,792,863 (-)NCBIT2T-CHM13v2.0
Timm8a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X133,438,005 - 133,442,419 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX133,438,005 - 133,442,614 (-)EnsemblGRCm39 Ensembl
GRCm38X134,537,256 - 134,541,670 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX134,537,256 - 134,541,865 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X131,071,797 - 131,076,168 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X129,883,608 - 129,887,979 (-)NCBIMGSCv36mm8
CeleraX117,416,827 - 117,421,171 (-)NCBICelera
Cytogenetic MapXE3NCBI
cM MapX56.18NCBI
Timm8a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555037,480,075 - 7,483,218 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555037,480,075 - 7,483,218 (-)NCBIChiLan1.0ChiLan1.0
TIMM8A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X100,940,770 - 100,948,316 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X100,941,231 - 100,951,911 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X90,548,212 - 90,551,534 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X100,680,224 - 100,683,553 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX100,680,224 - 100,683,544 (-)Ensemblpanpan1.1panPan2
TIMM8A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X75,267,437 - 75,270,288 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX75,267,450 - 75,270,288 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0X76,689,312 - 76,690,362 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X74,251,957 - 74,254,808 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X75,912,378 - 75,915,229 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X75,674,818 - 75,677,669 (-)NCBIUU_Cfam_GSD_1.0
Timm8a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X63,046,368 - 63,049,115 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936813425,613 - 428,702 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936813425,613 - 428,722 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TIMM8A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX82,974,270 - 82,980,769 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X82,978,128 - 82,981,038 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X91,010,563 - 91,013,448 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TIMM8A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X89,686,772 - 89,690,088 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX89,687,304 - 89,689,810 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606514,605,999 - 14,609,337 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Timm8a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249021,216,991 - 1,223,426 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Timm8a1
89 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:127
Count of miRNA genes:116
Interacting mature miRNAs:119
Transcripts:ENSRNOT00000015043, ENSRNOT00000072652
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX41304447112935181Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X65612192120568734Rat
724551Glom1Glomerulus QTL 12.80.0004kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)X75294106120294106Rat
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X93956491138956491Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 39 11 8
Low 2
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000015043   ⟹   ENSRNOP00000015043
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX105,352,402 - 105,355,716 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000108899   ⟹   ENSRNOP00000084461
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX97,717,920 - 97,721,960 (-)Ensembl
RefSeq Acc Id: NM_053370   ⟹   NP_445822
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X102,011,206 - 102,015,444 (-)NCBI
mRatBN7.2X97,717,932 - 97,722,170 (-)NCBI
Rnor_6.0X105,351,714 - 105,355,722 (-)NCBI
Rnor_5.0X105,241,128 - 105,245,441 (-)NCBI
RGSC_v3.4X121,993,810 - 121,997,685 (-)RGD
CeleraX98,758,800 - 98,762,786 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_445822 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD39989 (Get FASTA)   NCBI Sequence Viewer  
  AAH60552 (Get FASTA)   NCBI Sequence Viewer  
  EDM07024 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000084461
  ENSRNOP00000084461.1
  ENSRNOP00060028011
  ENSRNOP00065007142
GenBank Protein Q9WVA1 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_445822   ⟸   NM_053370
- UniProtKB: Q9WVA1 (UniProtKB/Swiss-Prot),   A6IVF6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000015043   ⟸   ENSRNOT00000015043
RefSeq Acc Id: ENSRNOP00000084461   ⟸   ENSRNOT00000108899
Protein Domains
Tim10-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9WVA1-F1-model_v2 AlphaFold Q9WVA1 1-97 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701933
Promoter ID:EPDNEW_R12457
Type:initiation region
Name:Timm8a1_1
Description:translocase of inner mitochondrial membrane 8 homolog A1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X105,355,761 - 105,355,821EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621801 AgrOrtholog
BioCyc Gene G2FUF-1684 BioCyc
Ensembl Genes ENSRNOG00000011226 Ensembl
  ENSRNOG00000064119 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00060019793 UniProtKB/Swiss-Prot
  ENSRNOG00065006401 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000108899 ENTREZGENE
  ENSRNOT00000108899.1 UniProtKB/Swiss-Prot
  ENSRNOT00060034171 UniProtKB/Swiss-Prot
  ENSRNOT00065009838 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.287.810 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6921445 IMAGE-MGC_LOAD
InterPro Tim10-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tim10-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:84383 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:72748 IMAGE-MGC_LOAD
NCBI Gene 84383 ENTREZGENE
Pfam zf-Tim10_DDP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Timm8a1 PhenoGen
RatGTEx ENSRNOG00000011226 RatGTEx
  ENSRNOG00000064119 RatGTEx
  ENSRNOG00060019793 RatGTEx
  ENSRNOG00065006401 RatGTEx
Superfamily-SCOP SSF144122 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A6IVF6 ENTREZGENE, UniProtKB/TrEMBL
  Q9WVA1 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-03-01 Timm8a1  translocase of inner mitochondrial membrane 8A1  Timm8a1  translocase of inner mitochondrial membrane 8 homolog A1 (yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-11-11 Timm8a1  translocase of inner mitochondrial membrane 8 homolog A1 (yeast)  Timm8a1  translocase of inner mitochondrial membrane 8 homolog a1 (yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-25 Timm8a1  translocase of inner mitochondrial membrane 8 homolog a1 (yeast)  Timm8a  translocase of inner mitochondrial membrane 8 homolog a (yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Timm8a  translocase of inner mitochondrial membrane 8 homolog a (yeast)    translocase of inner mitochondrial membrane 8 (yeast) homolog A  Name updated 1299863 APPROVED
2002-08-07 Timm8a  translocase of inner mitochondrial membrane 8 (yeast) homolog A      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_physical_interaction binds to STAM1, cytoplasmic signal-transducing adaptor molecule implicated in cytokine signaling 724770