MAS1L (MAS1 proto-oncogene like, G protein-coupled receptor) - Rat Genome Database

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Gene: MAS1L (MAS1 proto-oncogene like, G protein-coupled receptor) Homo sapiens
Analyze
Symbol: MAS1L
Name: MAS1 proto-oncogene like, G protein-coupled receptor
RGD ID: 1351772
HGNC Page HGNC:13961
Description: Predicted to enable angiotensin receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Located in cytosol; nucleoplasm; and plasma membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: dJ994E9.2; MAS-L; MAS-R; mas-related G protein-coupled MRG; mas-related G-protein coupled receptor MRG; MAS1 oncogene-like; MAS1-like; MGC119987; MRG
RGD Orthologs
Mouse
Rat
Bonobo
Alliance Orthologs
More Info more info ...
Related Pseudogenes: GPR53P   MAS1LP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38629,486,697 - 29,487,956 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl629,486,697 - 29,487,956 (-)EnsemblGRCh38hg38GRCh38
GRCh37629,454,474 - 29,455,733 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36629,562,522 - 29,563,658 (-)NCBINCBI36Build 36hg18NCBI36
Build 34629,562,521 - 29,563,658NCBI
Celera631,060,587 - 31,061,723 (-)NCBICelera
Cytogenetic Map6p22.1NCBI
HuRef629,261,701 - 29,262,837 (-)NCBIHuRef
CHM1_1629,456,662 - 29,457,798 (-)NCBICHM1_1
T2T-CHM13v2.0629,361,354 - 29,362,613 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
megacolon  (IAGP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IDA)
membrane  (IEA,NAS)
nucleoplasm  (IDA)
plasma membrane  (IBA,IDA,IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Megacolon  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1723144   PMID:11551509   PMID:12477932   PMID:14574404   PMID:15489334   PMID:18029348   PMID:18636314   PMID:19851445   PMID:21873635   PMID:33961781  


Genomics

Comparative Map Data
MAS1L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38629,486,697 - 29,487,956 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl629,486,697 - 29,487,956 (-)EnsemblGRCh38hg38GRCh38
GRCh37629,454,474 - 29,455,733 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36629,562,522 - 29,563,658 (-)NCBINCBI36Build 36hg18NCBI36
Build 34629,562,521 - 29,563,658NCBI
Celera631,060,587 - 31,061,723 (-)NCBICelera
Cytogenetic Map6p22.1NCBI
HuRef629,261,701 - 29,262,837 (-)NCBIHuRef
CHM1_1629,456,662 - 29,457,798 (-)NCBICHM1_1
T2T-CHM13v2.0629,361,354 - 29,362,613 (-)NCBIT2T-CHM13v2.0
Mrgprh
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391713,094,921 - 13,096,729 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1713,094,921 - 13,096,864 (+)EnsemblGRCm39 Ensembl
GRCm381712,876,034 - 12,877,842 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1712,876,034 - 12,877,977 (+)EnsemblGRCm38mm10GRCm38
MGSCv371713,068,900 - 13,070,708 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361712,718,966 - 12,720,774 (+)NCBIMGSCv36mm8
Celera1712,907,930 - 12,909,738 (+)NCBICelera
Cytogenetic Map17A1NCBI
cM Map178.7NCBI
Mas1l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8150,416,178 - 50,427,730 (-)NCBIGRCr8
mRatBN7.2147,871,592 - 47,879,942 (-)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx148,564,118 - 48,565,083 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0154,549,908 - 54,550,873 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0148,639,637 - 48,640,602 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0148,068,389 - 48,206,902 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl148,069,194 - 48,070,536 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0151,546,345 - 51,683,995 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4142,146,949 - 42,147,914 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1142,149,893 - 42,150,859 (-)NCBI
Celera143,672,936 - 43,673,901 (-)NCBICelera
Cytogenetic Map1q11NCBI
MAS1L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2544,110,393 - 44,172,799 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1640,073,708 - 40,136,145 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0629,295,079 - 29,357,477 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1629,955,683 - 29,957,161 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl629,955,952 - 29,957,161 (-)Ensemblpanpan1.1panPan2

Variants

.
Variants in MAS1L
22 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 6p22.3-21.33(chr6:18120520-30767516)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052180]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052180]|See cases [RCV000052180] Chr6:18120520..30767516 [GRCh38]
Chr6:18120751..30735293 [GRCh37]
Chr6:18228730..30843272 [NCBI36]
Chr6:6p22.3-21.33		 pathogenic
NM_052967.1(MAS1L):c.467C>T (p.Ser156Phe) single nucleotide variant Malignant melanoma [RCV000067262] Chr6:29487436 [GRCh38]
Chr6:29455213 [GRCh37]
Chr6:29563192 [NCBI36]
Chr6:6p22.1		 not provided
GRCh38/hg38 6p25.2-21.33(chr6:3224310-30657190)x3 copy number gain See cases [RCV000138956] Chr6:3224310..30657190 [GRCh38]
Chr6:3224544..30624967 [GRCh37]
Chr6:3169543..30732946 [NCBI36]
Chr6:6p25.2-21.33		 pathogenic
GRCh38/hg38 6p22.1(chr6:28763187-29769828)x3 copy number gain See cases [RCV000141858] Chr6:28763187..29769828 [GRCh38]
Chr6:28730964..29737605 [GRCh37]
Chr6:28838943..29845584 [NCBI36]
Chr6:6p22.1		 uncertain significance
GRCh38/hg38 6p25.3-12.3(chr6:156974-46789291)x3 copy number gain See cases [RCV000143497] Chr6:156974..46789291 [GRCh38]
Chr6:156974..46757028 [GRCh37]
Chr6:101974..46864987 [NCBI36]
Chr6:6p25.3-12.3		 pathogenic
GRCh37/hg19 6p22.1(chr6:28735761-29585573)x1 copy number loss See cases [RCV000445803] Chr6:28735761..29585573 [GRCh37]
Chr6:6p22.1		 uncertain significance
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3 copy number gain See cases [RCV000512067] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482) copy number gain See cases [RCV000510595] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3 copy number gain not provided [RCV000745403] Chr6:108666..170980171 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3 copy number gain not provided [RCV000745400] Chr6:60107..171054786 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3 copy number gain not provided [RCV000745404] Chr6:165632..170919470 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p22.1-21.32(chr6:28130359-32108367)x3 copy number gain not provided [RCV000745592] Chr6:28130359..32108367 [GRCh37]
Chr6:6p22.1-21.32		 uncertain significance
GRCh37/hg19 6p22.1(chr6:29452958-29501514)x1 copy number loss not provided [RCV000745611] Chr6:29452958..29501514 [GRCh37]
Chr6:6p22.1		 benign
GRCh37/hg19 6p22.1-q14.1(chr6:29455465-81447367) copy number gain not provided [RCV000767714] Chr6:29455465..81447367 [GRCh37]
Chr6:6p22.1-q14.1		 pathogenic
NM_052967.2(MAS1L):c.189G>T (p.Gln63His) single nucleotide variant not specified [RCV004297025] Chr6:29487714 [GRCh38]
Chr6:29455491 [GRCh37]
Chr6:6p22.1		 uncertain significance
GRCh37/hg19 6p22.1(chr6:29162783-30236331)x3 copy number gain not provided [RCV002472477] Chr6:29162783..30236331 [GRCh37]
Chr6:6p22.1		 uncertain significance
NC_000006.11:g.28005012_31683185del deletion Megacolon [RCV001290055] Chr6:28005012..31683185 [GRCh37]
Chr6:6p22.1-21.33		 likely pathogenic
GRCh37/hg19 6p22.1(chr6:28735761-29585573) copy number loss not specified [RCV002053563] Chr6:28735761..29585573 [GRCh37]
Chr6:6p22.1		 uncertain significance
NM_052967.2(MAS1L):c.661T>C (p.Cys221Arg) single nucleotide variant not specified [RCV004230513] Chr6:29487242 [GRCh38]
Chr6:29455019 [GRCh37]
Chr6:6p22.1		 uncertain significance
NM_052967.2(MAS1L):c.1052G>A (p.Gly351Asp) single nucleotide variant not specified [RCV004216275] Chr6:29486851 [GRCh38]
Chr6:29454628 [GRCh37]
Chr6:6p22.1		 uncertain significance
NM_052967.2(MAS1L):c.718T>G (p.Cys240Gly) single nucleotide variant not specified [RCV004188432] Chr6:29487185 [GRCh38]
Chr6:29454962 [GRCh37]
Chr6:6p22.1		 uncertain significance
NM_052967.2(MAS1L):c.697G>T (p.Ala233Ser) single nucleotide variant not specified [RCV004148303] Chr6:29487206 [GRCh38]
Chr6:29454983 [GRCh37]
Chr6:6p22.1		 uncertain significance
NM_052967.2(MAS1L):c.284C>T (p.Thr95Ile) single nucleotide variant not specified [RCV004083836] Chr6:29487619 [GRCh38]
Chr6:29455396 [GRCh37]
Chr6:6p22.1		 uncertain significance
NM_052967.2(MAS1L):c.806C>T (p.Ser269Leu) single nucleotide variant not specified [RCV004073969] Chr6:29487097 [GRCh38]
Chr6:29454874 [GRCh37]
Chr6:6p22.1		 uncertain significance
NM_052967.2(MAS1L):c.1123G>A (p.Asp375Asn) single nucleotide variant not provided [RCV004695384]|not specified [RCV004090865] Chr6:29486780 [GRCh38]
Chr6:29454557 [GRCh37]
Chr6:6p22.1		 uncertain significance
NM_052967.2(MAS1L):c.554G>A (p.Arg185His) single nucleotide variant not specified [RCV004255287] Chr6:29487349 [GRCh38]
Chr6:29455126 [GRCh37]
Chr6:6p22.1		 uncertain significance
NM_052967.2(MAS1L):c.511C>T (p.Arg171Trp) single nucleotide variant not specified [RCV004285115] Chr6:29487392 [GRCh38]
Chr6:29455169 [GRCh37]
Chr6:6p22.1		 likely benign
NM_052967.2(MAS1L):c.304T>C (p.Cys102Arg) single nucleotide variant not specified [RCV004272761] Chr6:29487599 [GRCh38]
Chr6:29455376 [GRCh37]
Chr6:6p22.1		 uncertain significance
NM_052967.2(MAS1L):c.239C>G (p.Pro80Arg) single nucleotide variant not specified [RCV004297838] Chr6:29487664 [GRCh38]
Chr6:29455441 [GRCh37]
Chr6:6p22.1		 uncertain significance
NM_052967.2(MAS1L):c.96C>A (p.His32Gln) single nucleotide variant not specified [RCV004346523] Chr6:29487807 [GRCh38]
Chr6:29455584 [GRCh37]
Chr6:6p22.1		 uncertain significance
NM_052967.2(MAS1L):c.418G>A (p.Gly140Arg) single nucleotide variant not specified [RCV004353123] Chr6:29487485 [GRCh38]
Chr6:29455262 [GRCh37]
Chr6:6p22.1		 uncertain significance
NM_052967.2(MAS1L):c.349G>A (p.Ala117Thr) single nucleotide variant not specified [RCV004416524] Chr6:29487554 [GRCh38]
Chr6:29455331 [GRCh37]
Chr6:6p22.1		 uncertain significance
NM_052967.2(MAS1L):c.563A>G (p.Tyr188Cys) single nucleotide variant not specified [RCV004416527] Chr6:29487340 [GRCh38]
Chr6:29455117 [GRCh37]
Chr6:6p22.1		 uncertain significance
NM_052967.2(MAS1L):c.220C>A (p.Pro74Thr) single nucleotide variant not specified [RCV004416523] Chr6:29487683 [GRCh38]
Chr6:29455460 [GRCh37]
Chr6:6p22.1		 uncertain significance
NM_052967.2(MAS1L):c.358G>A (p.Val120Met) single nucleotide variant not specified [RCV004416525] Chr6:29487545 [GRCh38]
Chr6:29455322 [GRCh37]
Chr6:6p22.1		 uncertain significance
NM_052967.2(MAS1L):c.547T>G (p.Cys183Gly) single nucleotide variant not specified [RCV004416526] Chr6:29487356 [GRCh38]
Chr6:29455133 [GRCh37]
Chr6:6p22.1		 uncertain significance
NM_052967.2(MAS1L):c.773A>C (p.Lys258Thr) single nucleotide variant not specified [RCV004416528] Chr6:29487130 [GRCh38]
Chr6:29454907 [GRCh37]
Chr6:6p22.1		 uncertain significance
NM_052967.2(MAS1L):c.844G>A (p.Val282Met) single nucleotide variant not specified [RCV004416529] Chr6:29487059 [GRCh38]
Chr6:29454836 [GRCh37]
Chr6:6p22.1		 likely benign
NM_052967.2(MAS1L):c.616A>G (p.Ile206Val) single nucleotide variant not specified [RCV004636571] Chr6:29487287 [GRCh38]
Chr6:29455064 [GRCh37]
Chr6:6p22.1		 uncertain significance
NM_052967.2(MAS1L):c.1057G>A (p.Asp353Asn) single nucleotide variant not specified [RCV004636570] Chr6:29486846 [GRCh38]
Chr6:29454623 [GRCh37]
Chr6:6p22.1		 uncertain significance
NM_052967.2(MAS1L):c.49G>A (p.Val17Met) single nucleotide variant not specified [RCV004636572] Chr6:29487854 [GRCh38]
Chr6:29455631 [GRCh37]
Chr6:6p22.1		 uncertain significance
NM_052967.2(MAS1L):c.949G>A (p.Val317Met) single nucleotide variant not specified [RCV004643106] Chr6:29486954 [GRCh38]
Chr6:29454731 [GRCh37]
Chr6:6p22.1		 uncertain significance
NM_052967.2(MAS1L):c.880A>G (p.Thr294Ala) single nucleotide variant not specified [RCV004643107] Chr6:29487023 [GRCh38]
Chr6:29454800 [GRCh37]
Chr6:6p22.1		 uncertain significance
NM_052967.2(MAS1L):c.894A>C (p.Leu298Phe) single nucleotide variant not specified [RCV004643108] Chr6:29487009 [GRCh38]
Chr6:29454786 [GRCh37]
Chr6:6p22.1		 uncertain significance
NM_052967.2(MAS1L):c.643T>C (p.Trp215Arg) single nucleotide variant not specified [RCV004636569] Chr6:29487260 [GRCh38]
Chr6:29455037 [GRCh37]
Chr6:6p22.1		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:238
Count of miRNA genes:230
Interacting mature miRNAs:237
Transcripts:ENST00000377127
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358854MULTSCL4_HMultiple sclerosis susceptibility QTL 4 (human)Multiple sclerosis susceptibility6691196032911960Human
1358839MULTSCL5_HMultiple sclerosis susceptibility QTL 5 (human)Multiple sclerosis susceptibility61958431145584311Human
1643377BW325_HBody weight QTL 325 (human)2.320.0005Body fat amount6691196032911960Human
1643569GLUCO21_HGlucose level QTL 21 (human)0.021Glucose levelnon-insulin-dependent6691196032911960Human
1298458BW9_HBody weight QTL 9 (human)2.70.0002Body fat amount6691196032911960Human
1298431RA11_HRheumatoid arthritis QTL 11 (human)0.0000024Joint/bone inflammationrheumatoid arthritis61991188340191709Human
1358857MULTSCL19_HMultiple sclerosis susceptibility QTL 19 (human)Multiple sclerosis susceptibility61958431145584311Human
1643399BMD5_HBone mineral density QTL 5 (human)2.320.0005Bone mineral density6691196032911960Human

Markers in Region
RH70224  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37629,454,424 - 29,454,544UniSTSGRCh37
Build 36629,562,403 - 29,562,523RGDNCBI36
Celera631,060,468 - 31,060,588RGD
Cytogenetic Map6p21UniSTS
HuRef629,261,582 - 29,261,702UniSTS
GeneMap99-GB4 RH Map6108.65UniSTS
UniSTS:480553  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37629,454,543 - 29,455,679UniSTSGRCh37
Celera631,060,587 - 31,061,723UniSTS
HuRef629,261,701 - 29,262,837UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
1030 1886 1907 1111 1583 541 974 315 488 170 1837 3182 3336 1 872 467 958 594 145

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_052967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AL035542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL645927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL662869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC069127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC069345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC095511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC101176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC101177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX000531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX247947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX927133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR388393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR759768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR759956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S78653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000377127   ⟹   ENSP00000366331
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl629,486,697 - 29,487,956 (-)Ensembl
RefSeq Acc Id: NM_052967   ⟹   NP_443199
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38629,486,697 - 29,487,956 (-)NCBI
GRCh37629,454,543 - 29,455,679 (-)RGD
Build 36629,562,522 - 29,563,658 (-)NCBI Archive
Celera631,060,587 - 31,061,723 (-)RGD
HuRef629,261,701 - 29,262,837 (-)RGD
CHM1_1629,456,662 - 29,457,798 (-)NCBI
T2T-CHM13v2.0629,361,354 - 29,362,613 (-)NCBI
Sequence:
RefSeq Acc Id: NP_443199   ⟸   NM_052967
- UniProtKB: Q5SUN5 (UniProtKB/Swiss-Prot),   P35410 (UniProtKB/Swiss-Prot),   W8W3J1 (UniProtKB/TrEMBL),   A0A1U9X807 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000366331   ⟸   ENST00000377127
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P35410-F1-model_v2 AlphaFold P35410 1-378 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:13961 AgrOrtholog
COSMIC MAS1L COSMIC
Ensembl Genes ENSG00000204687 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSG00000206470 UniProtKB/Swiss-Prot
  ENSG00000206515 UniProtKB/Swiss-Prot
  ENSG00000228377 UniProtKB/Swiss-Prot
  ENSG00000228515 UniProtKB/Swiss-Prot
  ENSG00000233141 UniProtKB/Swiss-Prot
  ENSG00000234954 UniProtKB/Swiss-Prot
  ENSG00000237284 UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000377127 ENTREZGENE
  ENST00000377127.4 UniProtKB/Swiss-Prot
  ENST00000383549.3 UniProtKB/Swiss-Prot
  ENST00000383643.3 UniProtKB/Swiss-Prot
  ENST00000415802.3 UniProtKB/Swiss-Prot
  ENST00000418003.3 UniProtKB/Swiss-Prot
  ENST00000420035.3 UniProtKB/Swiss-Prot
  ENST00000449044.3 UniProtKB/Swiss-Prot
  ENST00000451019.3 UniProtKB/Swiss-Prot
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000204687 GTEx
  ENSG00000206470 GTEx
  ENSG00000206515 GTEx
  ENSG00000228377 GTEx
  ENSG00000228515 GTEx
  ENSG00000233141 GTEx
  ENSG00000234954 GTEx
  ENSG00000237284 GTEx
HGNC ID HGNC:13961 ENTREZGENE
Human Proteome Map MAS1L Human Proteome Map
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MRGPCRFAMILY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:116511 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 116511 ENTREZGENE
OMIM 607235 OMIM
PANTHER MAS-RELATED G-PROTEIN COUPLED RECEPTOR MRG-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11334 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134912067 PharmGKB
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MRGPCRFAMILY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1U9X807 ENTREZGENE, UniProtKB/TrEMBL
  MAS1L_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q502V9_HUMAN UniProtKB/TrEMBL
  Q5SUN5 ENTREZGENE
  W8W3J1 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q5SUN5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-07-01 MAS1L  MAS1 proto-oncogene like, G protein-coupled receptor    MAS1 oncogene-like  Symbol and/or name change 5135510 APPROVED