Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | decreases expression | ISO | RGD:1623021 | 6480464 | ethylene dichloride results in decreased expression of PLXNB3 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | increases expression | ISO | RGD:1623021 | 6480464 | 1, 2-Dimethylhydrazine results in increased expression of PLXNB3 mRNA | CTD | PMID:22206623 | 17beta-estradiol | multiple interactions | ISO | RGD:1560615 | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of PLXNB3 mRNA | CTD | PMID:32741896 | 17beta-estradiol 3-benzoate | multiple interactions | ISO | RGD:1560615 | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of PLXNB3 mRNA | CTD | PMID:32741896 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1623021 | 6480464 | Tetrachlorodibenzodioxin affects the expression of PLXNB3 mRNA | CTD | PMID:21570461 | 6-propyl-2-thiouracil | decreases expression | ISO | RGD:1560615 | 6480464 | Propylthiouracil results in decreased expression of PLXNB3 mRNA | CTD | PMID:24780913 | acrylamide | decreases expression | ISO | RGD:1623021 | 6480464 | Acrylamide results in decreased expression of PLXNB3 mRNA | CTD | PMID:29261810 | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of PLXNB3 mRNA | CTD | PMID:32763439 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of PLXNB3 mRNA | CTD | PMID:32234424 | Aflatoxin B2 alpha | increases methylation | EXP | | 6480464 | aflatoxin B2 results in increased methylation of PLXNB3 polyA tail | CTD | PMID:30157460 | arsenite(3-) | decreases expression | ISO | RGD:1623021 | 6480464 | arsenite results in decreased expression of PLXNB3 mRNA | CTD | PMID:18929588 | arsenite(3-) | multiple interactions | ISO | RGD:1623021 | 6480464 | TRP53 protein affects the reaction [arsenite results in decreased expression of PLXNB3 mRNA] | CTD | PMID:18929588 | benzo[a]pyrene | decreases methylation | EXP | | 6480464 | Benzo(a)pyrene results in decreased methylation of PLXNB3 3' UTR | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of PLXNB3 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | affects methylation | EXP | | 6480464 | Benzo(a)pyrene affects the methylation of PLXNB3 5' UTR more ... | CTD | PMID:27901495, PMID:30157460 | bisphenol A | affects expression | ISO | RGD:1560615 | 6480464 | bisphenol A affects the expression of PLXNB3 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | RGD:1560615 | 6480464 | bisphenol A results in decreased expression of PLXNB3 mRNA | CTD | PMID:34947998 | cadmium dichloride | increases expression | ISO | RGD:1560615 | 6480464 | Cadmium Chloride results in increased expression of PLXNB3 mRNA | CTD | PMID:33453195 | calcitriol | increases expression | EXP | | 6480464 | Calcitriol results in increased expression of PLXNB3 mRNA | CTD | PMID:26485663 | cannabidiol | decreases expression | EXP | | 6480464 | Cannabidiol results in decreased expression of PLXNB3 mRNA | CTD | PMID:27918106 | cisplatin | multiple interactions | EXP | | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of PLXNB3 mRNA | CTD | PMID:27392435 | cisplatin | increases expression | EXP | | 6480464 | Cisplatin results in increased expression of PLXNB3 mRNA | CTD | PMID:27392435 | copper atom | increases expression | ISO | RGD:1560615 | 6480464 | Copper deficiency results in increased expression of PLXNB3 mRNA | CTD | PMID:26033743 | copper atom | multiple interactions | EXP | | 6480464 | [Chelating Agents binds to Copper] which results in decreased expression of PLXNB3 mRNA | CTD | PMID:31162603 | copper(0) | increases expression | ISO | RGD:1560615 | 6480464 | Copper deficiency results in increased expression of PLXNB3 mRNA | CTD | PMID:26033743 | copper(0) | multiple interactions | EXP | | 6480464 | [Chelating Agents binds to Copper] which results in decreased expression of PLXNB3 mRNA | CTD | PMID:31162603 | Cuprizon | decreases expression | ISO | RGD:1560615 | 6480464 | Cuprizone results in decreased expression of PLXNB3 mRNA | CTD | PMID:26577399, PMID:27523638 | hydrogen peroxide | increases expression | EXP | | 6480464 | Hydrogen Peroxide results in increased expression of PLXNB3 mRNA | CTD | PMID:32949572 | mercury atom | decreases expression | ISO | RGD:1623021 | 6480464 | Mercury analog results in decreased expression of PLXNB3 mRNA | CTD | PMID:25056781 | mercury(0) | decreases expression | ISO | RGD:1623021 | 6480464 | Mercury analog results in decreased expression of PLXNB3 mRNA | CTD | PMID:25056781 | methylmercury chloride | decreases expression | ISO | RGD:1623021 | 6480464 | methylmercuric chloride results in decreased expression of PLXNB3 mRNA | CTD | PMID:29261810 | propanal | increases expression | EXP | | 6480464 | propionaldehyde results in increased expression of PLXNB3 mRNA | CTD | PMID:26079696 | testosterone | multiple interactions | ISO | RGD:1560615 | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of PLXNB3 mRNA | CTD | PMID:32741896 | triclosan | increases expression | EXP | | 6480464 | Triclosan results in increased expression of PLXNB3 mRNA | CTD | PMID:30510588 | triptonide | increases expression | ISO | RGD:1623021 | 6480464 | triptonide results in increased expression of PLXNB3 mRNA | CTD | PMID:33045310 | valproic acid | increases methylation | EXP | | 6480464 | Valproic Acid results in increased methylation of PLXNB3 gene | CTD | PMID:29154799 | valproic acid | decreases expression | ISO | RGD:1623021 | 6480464 | Valproic Acid results in decreased expression of PLXNB3 mRNA | CTD | PMID:29261810 | | 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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | GOAs Human GO annotations | GOA_HUMAN data from the GO Consortium |
| 2. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
| 3. | Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates. | Tamagnone L, etal., Cell 1999 Oct 1;99(1):71-80. |
Additional References at PubMed
| PMID:8661155 | PMID:10574462 | PMID:12123608 | PMID:12183458 | PMID:12421765 | PMID:15184888 | PMID:15218527 | PMID:15790807 | PMID:16122393 | PMID:17033634 | PMID:19329067 | PMID:19850054 |
| PMID:20696765 | PMID:21706053 | PMID:21873635 | PMID:29676528 | PMID:34267322 |
Genomics
