Plxna1 (plexin A1) - Rat Genome Database
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Gene: Plxna1 (plexin A1) Mus musculus
Analyze
Symbol: Plxna1
Name: plexin A1
RGD ID: 1557807
MGI Page MGI
Description: Is expressed in several structures, including central nervous system; cranial nerve; genitourinary system; lung; and sensory organ. Orthologous to human PLXNA1 (plexin A1); INTERACTS WITH 1,1-dichloroethene; 1,2-dimethylhydrazine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2600013D04Rik; KIAA4053; mKIAA4053; NOV; Pl; Ple; plex 1; PlexA1; plexin 1; plexin-1; plexin-A1; Plxn1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39689,293,295 - 89,339,595 (-)NCBIGRCm39mm39
GRCm39 Ensembl689,293,296 - 89,339,602 (-)Ensembl
GRCm38689,316,313 - 89,362,613 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl689,316,314 - 89,362,620 (-)EnsemblGRCm38mm10GRCm38
MGSCv37689,266,307 - 89,312,607 (-)NCBIGRCm37mm9NCBIm37
MGSCv36689,284,498 - 89,328,239 (-)NCBImm8
Celera691,240,510 - 91,288,949 (-)NCBICelera
Cytogenetic Map6D1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

Additional References at PubMed
PMID:8806646   PMID:8806667   PMID:8889548   PMID:10349636   PMID:10520994   PMID:10725340   PMID:10781943   PMID:11042159   PMID:11076861   PMID:11108845   PMID:11241833   PMID:11306810  
PMID:11442635   PMID:11688557   PMID:12477932   PMID:12520002   PMID:12559962   PMID:12904583   PMID:12910265   PMID:14734633   PMID:14977921   PMID:15033168   PMID:15239958   PMID:15661641  
PMID:15741177   PMID:15869472   PMID:15996756   PMID:16141072   PMID:16141073   PMID:16286926   PMID:16452166   PMID:16512683   PMID:16602821   PMID:16715077   PMID:16982860   PMID:17145500  
PMID:17197097   PMID:17356169   PMID:17626059   PMID:18287072   PMID:18287559   PMID:18489001   PMID:18617019   PMID:18625214   PMID:18804103   PMID:19063725   PMID:19655386   PMID:20138877  
PMID:20159958   PMID:20412781   PMID:20512151   PMID:21075075   PMID:21267068   PMID:21270798   PMID:21440680   PMID:21491433   PMID:21508241   PMID:21525298   PMID:21831918   PMID:21835343  
PMID:21873635   PMID:22213797   PMID:22368082   PMID:22505034   PMID:22522930   PMID:22632726   PMID:22723296   PMID:22998873   PMID:23954273   PMID:23988635   PMID:23991118   PMID:24179230  
PMID:24360543   PMID:24604454   PMID:24733831   PMID:24952961   PMID:25313870   PMID:25485759   PMID:25839327   PMID:25843547   PMID:25959730   PMID:25975775   PMID:26319580   PMID:26633812  
PMID:26680304   PMID:27397516   PMID:27717823   PMID:28172500   PMID:28215559   PMID:28334861   PMID:28407732   PMID:28558017   PMID:28751609   PMID:28893946   PMID:29031500   PMID:29358640  
PMID:29777213   PMID:30353093   PMID:31209173   PMID:31430342   PMID:31690636   PMID:32325033   PMID:32471877  


Genomics

Comparative Map Data
Plxna1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39689,293,295 - 89,339,595 (-)NCBIGRCm39mm39
GRCm39 Ensembl689,293,296 - 89,339,602 (-)Ensembl
GRCm38689,316,313 - 89,362,613 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl689,316,314 - 89,362,620 (-)EnsemblGRCm38mm10GRCm38
MGSCv37689,266,307 - 89,312,607 (-)NCBIGRCm37mm9NCBIm37
MGSCv36689,284,498 - 89,328,239 (-)NCBImm8
Celera691,240,510 - 91,288,949 (-)NCBICelera
Cytogenetic Map6D1NCBI
PLXNA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3126,988,594 - 127,037,392 (+)EnsemblGRCh38hg38GRCh38
GRCh383126,983,115 - 127,037,389 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373126,701,958 - 126,756,232 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363128,190,192 - 128,238,922 (+)NCBINCBI36hg18NCBI36
Build 343128,190,199 - 128,238,926NCBI
Celera3125,131,626 - 125,180,424 (+)NCBI
Cytogenetic Map3q21.3NCBI
HuRef3124,086,407 - 124,135,205 (+)NCBIHuRef
CHM1_13126,670,452 - 126,719,250 (+)NCBICHM1_1
Plxna1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24121,737,934 - 121,782,901 (-)NCBI
Rnor_6.0 Ensembl4121,217,629 - 121,257,885 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04121,217,658 - 121,262,697 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04186,455,209 - 186,500,246 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44123,395,675 - 123,432,697 (-)NCBIRGSC3.4rn4RGSC3.4
Celera4110,688,907 - 110,729,767 (-)NCBICelera
Cytogenetic Map4q34NCBI
Plxna1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542916,482,725 - 16,522,973 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542916,482,821 - 16,522,978 (-)NCBIChiLan1.0ChiLan1.0
PLXNA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13131,340,943 - 131,393,561 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3131,340,584 - 131,393,561 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03124,026,069 - 124,080,241 (+)NCBIMhudiblu_PPA_v0panPan3
PLXNA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl20870,870 - 1,184,321 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1201,143,072 - 1,186,623 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Plxna1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936798951,138 - 989,955 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLXNA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1373,054,443 - 73,098,914 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11373,054,434 - 73,098,786 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21380,508,136 - 80,608,330 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLXNA1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12253,949,566 - 54,005,626 (-)NCBI
ChlSab1.1 Ensembl2253,951,119 - 53,999,812 (-)Ensembl
Plxna1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249002,779,008 - 2,825,263 (+)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63866962592607450Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
15039373Adip28_madiposity 28 (mouse)65630821190308211Mouse
15039375Bw41_mbody weight QTL 41 (mouse)65630821190308211Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65844758392447710Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65854043392540433Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66005768094057799Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66348473897484905Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666713869100714031Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670425898104426034Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670425898104426034Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670425898104426034Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67132262193464093Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671575060105575178Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671981024105981170Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671981024105981170Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673500000134700000Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675447583104503555Mouse
1301571Arrd1_mage-related retinal degeneration 1 (mouse)Not determined67554435692607450Mouse
1300674Nidd3n_mnon-insulin-dependent diabetes mellitus 3 in NSY (mouse)Not determined67554435694225955Mouse
10412195Efw_mepididymal fat weight (mouse)Not determined67554435694225955Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675607306109607450Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675716503109716697Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676463949110464093Mouse
14697704Stsl4_mSalmonella typhimurium susceptibility locus 4 (mouse)67710000090000000Mouse
13824985Alh1_mamplitude of lateral head displacement 1 (mouse)67800000097000000Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678629504121115387Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681500000102200000Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683713869147052561Mouse
11251720Ewc4_methanol withdrawal and consumption 4 (mouse)684122513118122513Mouse
1301687Mnic2_mmacronutrient intake (mouse)Not determined686806805113544602Mouse
1301744Hdlq11_mHDL QTL 11 (mouse)Not determined687503360121503555Mouse
1301262Gasa3_mgastritis type A susceptibility locus 3 (mouse)Not determined689005405123005603Mouse
15090872Cbcq2_mcecum bacterial composition QTL 2 (mouse)68921000089370000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1541
Count of miRNA genes:728
Interacting mature miRNAs:905
Transcripts:ENSMUST00000049845, ENSMUST00000163139
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000049845   ⟹   ENSMUSP00000063066
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl689,319,015 - 89,357,717 (-)Ensembl
RefSeq Acc Id: ENSMUST00000163139   ⟹   ENSMUSP00000131840
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl689,316,314 - 89,362,620 (-)Ensembl
RefSeq Acc Id: ENSMUST00000204468   ⟹   ENSMUSP00000144822
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl689,322,515 - 89,324,633 (-)Ensembl
RefSeq Acc Id: ENSMUST00000204997
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl689,330,378 - 89,333,070 (-)Ensembl
RefSeq Acc Id: ENSMUST00000205121   ⟹   ENSMUSP00000145403
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl689,335,411 - 89,342,591 (-)Ensembl
RefSeq Acc Id: ENSMUST00000205230
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl689,320,624 - 89,321,089 (-)Ensembl
RefSeq Acc Id: NM_008881   ⟹   NP_032907
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39689,293,295 - 89,339,595 (-)NCBI
GRCm38689,316,313 - 89,362,613 (-)ENTREZGENE
MGSCv37689,266,307 - 89,312,607 (-)RGD
Celera691,240,510 - 91,288,949 (-)RGD
cM Map6 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_032907   ⟸   NM_008881
- Peptide Label: precursor
- UniProtKB: P70206 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000131840   ⟸   ENSMUST00000163139
RefSeq Acc Id: ENSMUSP00000145403   ⟸   ENSMUST00000205121
RefSeq Acc Id: ENSMUSP00000144822   ⟸   ENSMUST00000204468
RefSeq Acc Id: ENSMUSP00000063066   ⟸   ENSMUST00000049845
Protein Domains
IPT/TIG   Sema

Promoters
RGD ID:6848020
Promoter ID:MM_ACW:41957
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour
Transcripts:PLXNA1.CSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36689,274,146 - 89,274,646 (-)MPROMDB
RGD ID:6848018
Promoter ID:MM_ACW:41959
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour
Transcripts:PLXNA1.BSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36689,292,546 - 89,293,046 (-)MPROMDB
RGD ID:6839758
Promoter ID:MM_KWN:46849
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Lung
Transcripts:NM_008881
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36689,312,446 - 89,313,397 (-)MPROMDB
RGD ID:6890396
Promoter ID:EPDNEW_M8649
Type:initiation region
Name:Plxna1_1
Description:Mus musculus plexin A1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38689,362,563 - 89,362,623EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:107685 AgrOrtholog
Ensembl Genes ENSMUSG00000030084 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000063066 UniProtKB/Swiss-Prot
  ENSMUSP00000131840 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000144822 UniProtKB/TrEMBL
  ENSMUSP00000145403 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000049845 UniProtKB/Swiss-Prot
  ENSMUST00000163139 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000204468 UniProtKB/TrEMBL
  ENSMUST00000205121 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot
  2.60.40.10 UniProtKB/Swiss-Prot
InterPro Ig-like_fold UniProtKB/Swiss-Prot
  Ig_E-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IPT_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Plexin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Plexin-A1_Sema UniProtKB/Swiss-Prot
  Plexin_cytoplasmic_RasGAP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Plexin_repeat UniProtKB/Swiss-Prot
  PSI UniProtKB/Swiss-Prot
  Rho_GTPase_activation_prot UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Semap_dom UniProtKB/Swiss-Prot
  Semap_dom_sf UniProtKB/Swiss-Prot
  TIG1_plexin UniProtKB/Swiss-Prot
  TIG2_plexin UniProtKB/Swiss-Prot
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot
KEGG Report mmu:18844 UniProtKB/Swiss-Prot
MGD MGI:107685 ENTREZGENE
NCBI Gene 18844 ENTREZGENE
PANTHER PTHR22625 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Plexin_cytopl UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PSI UniProtKB/Swiss-Prot
  Sema UniProtKB/Swiss-Prot
  TIG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIG_2 UniProtKB/Swiss-Prot
  TIG_plexin UniProtKB/Swiss-Prot
PhenoGen Plxna1 PhenoGen
PROSITE SEMA UniProtKB/Swiss-Prot
SMART IPT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PSI UniProtKB/Swiss-Prot
  Sema UniProtKB/Swiss-Prot
Superfamily-SCOP SSF101912 UniProtKB/Swiss-Prot
  SSF48350 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF81296 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0N4SUU1_MOUSE UniProtKB/TrEMBL
  A0A0N4SW74_MOUSE UniProtKB/TrEMBL
  P70206 ENTREZGENE, UniProtKB/Swiss-Prot
  Q3U3W7_MOUSE UniProtKB/TrEMBL
UniProt Secondary B2RQP7 UniProtKB/Swiss-Prot
  Q5DTR0 UniProtKB/Swiss-Prot