Plxna1 (plexin A1) - Rat Genome Database
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Gene: Plxna1 (plexin A1) Mus musculus
Analyze
Symbol: Plxna1
Name: plexin A1
RGD ID: 1557807
MGI Page MGI
Description: Is expressed in several structures, including central nervous system; cranial nerve; genitourinary system; lung; and sensory organ. Orthologous to human PLXNA1 (plexin A1); INTERACTS WITH 1,1-dichloroethene; 1,2-dimethylhydrazine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2600013D04Rik; KIAA4053; mKIAA4053; NOV; Pl; Ple; plex 1; PlexA1; plexin 1; plexin-1; plexin-A1; Plxn1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39689,293,295 - 89,339,595 (-)NCBIGRCm39mm39
GRCm39 Ensembl689,293,296 - 89,339,602 (-)Ensembl
GRCm38689,316,313 - 89,362,613 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl689,316,314 - 89,362,620 (-)EnsemblGRCm38mm10GRCm38
MGSCv37689,266,307 - 89,312,607 (-)NCBIGRCm37mm9NCBIm37
MGSCv36689,284,498 - 89,328,239 (-)NCBImm8
Celera691,240,510 - 91,288,949 (-)NCBICelera
Cytogenetic Map6D1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:8806646   PMID:8806667   PMID:8889548   PMID:10349636   PMID:10520994   PMID:10725340   PMID:10781943   PMID:11042159   PMID:11076861   PMID:11108845   PMID:11241833   PMID:11306810  
PMID:11442635   PMID:11688557   PMID:12477932   PMID:12520002   PMID:12559962   PMID:12904583   PMID:12910265   PMID:14734633   PMID:14977921   PMID:15033168   PMID:15239958   PMID:15661641  
PMID:15741177   PMID:15869472   PMID:15996756   PMID:16141072   PMID:16141073   PMID:16286926   PMID:16452166   PMID:16512683   PMID:16602821   PMID:16715077   PMID:16982860   PMID:17145500  
PMID:17197097   PMID:17356169   PMID:17626059   PMID:18287072   PMID:18287559   PMID:18489001   PMID:18617019   PMID:18625214   PMID:18804103   PMID:19063725   PMID:19655386   PMID:20138877  
PMID:20159958   PMID:20412781   PMID:20512151   PMID:21075075   PMID:21267068   PMID:21270798   PMID:21440680   PMID:21491433   PMID:21508241   PMID:21525298   PMID:21831918   PMID:21835343  
PMID:21873635   PMID:22213797   PMID:22368082   PMID:22505034   PMID:22522930   PMID:22632726   PMID:22723296   PMID:22998873   PMID:23954273   PMID:23988635   PMID:23991118   PMID:24179230  
PMID:24360543   PMID:24604454   PMID:24733831   PMID:24952961   PMID:25313870   PMID:25485759   PMID:25839327   PMID:25843547   PMID:25959730   PMID:25975775   PMID:26319580   PMID:26633812  
PMID:26680304   PMID:27397516   PMID:27717823   PMID:28172500   PMID:28215559   PMID:28334861   PMID:28407732   PMID:28558017   PMID:28751609   PMID:28893946   PMID:29031500   PMID:29358640  
PMID:29777213   PMID:30353093   PMID:31209173   PMID:31430342   PMID:31690636   PMID:32325033   PMID:32471877  


Genomics

Comparative Map Data
Plxna1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39689,293,295 - 89,339,595 (-)NCBIGRCm39mm39
GRCm39 Ensembl689,293,296 - 89,339,602 (-)Ensembl
GRCm38689,316,313 - 89,362,613 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl689,316,314 - 89,362,620 (-)EnsemblGRCm38mm10GRCm38
MGSCv37689,266,307 - 89,312,607 (-)NCBIGRCm37mm9NCBIm37
MGSCv36689,284,498 - 89,328,239 (-)NCBImm8
Celera691,240,510 - 91,288,949 (-)NCBICelera
Cytogenetic Map6D1NCBI
PLXNA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3126,988,594 - 127,037,392 (+)EnsemblGRCh38hg38GRCh38
GRCh383126,983,115 - 127,037,389 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373126,701,958 - 126,756,232 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363128,190,192 - 128,238,922 (+)NCBINCBI36hg18NCBI36
Build 343128,190,199 - 128,238,926NCBI
Celera3125,131,626 - 125,180,424 (+)NCBI
Cytogenetic Map3q21.3NCBI
HuRef3124,086,407 - 124,135,205 (+)NCBIHuRef
CHM1_13126,670,452 - 126,719,250 (+)NCBICHM1_1
Plxna1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24121,737,934 - 121,782,901 (-)NCBI
Rnor_6.0 Ensembl4121,217,629 - 121,257,885 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04121,217,658 - 121,262,697 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04186,455,209 - 186,500,246 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44123,395,675 - 123,432,697 (-)NCBIRGSC3.4rn4RGSC3.4
Celera4110,688,907 - 110,729,767 (-)NCBICelera
Cytogenetic Map4q34NCBI
Plxna1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542916,482,725 - 16,522,973 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542916,482,821 - 16,522,978 (-)NCBIChiLan1.0ChiLan1.0
PLXNA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13131,340,943 - 131,393,561 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3131,340,584 - 131,393,561 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03124,026,069 - 124,080,241 (+)NCBIMhudiblu_PPA_v0panPan3
PLXNA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl20870,870 - 1,184,321 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1201,143,072 - 1,186,623 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Plxna1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936798951,138 - 989,955 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLXNA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1373,054,443 - 73,098,914 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11373,054,434 - 73,098,786 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21380,508,136 - 80,608,330 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLXNA1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12253,949,566 - 54,005,626 (-)NCBI
ChlSab1.1 Ensembl2253,951,119 - 53,999,812 (-)Ensembl
Plxna1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249002,779,008 - 2,825,263 (+)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63866962592607450Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
15039373Adip28_madiposity 28 (mouse)65630821190308211Mouse
15039375Bw41_mbody weight QTL 41 (mouse)65630821190308211Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65844758392447710Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65854043392540433Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66005768094057799Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66348473897484905Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666713869100714031Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670425898104426034Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670425898104426034Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670425898104426034Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67132262193464093Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671575060105575178Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671981024105981170Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671981024105981170Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673500000134700000Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675447583104503555Mouse
1301571Arrd1_mage-related retinal degeneration 1 (mouse)Not determined67554435692607450Mouse
1300674Nidd3n_mnon-insulin-dependent diabetes mellitus 3 in NSY (mouse)Not determined67554435694225955Mouse
10412195Efw_mepididymal fat weight (mouse)Not determined67554435694225955Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675607306109607450Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675716503109716697Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676463949110464093Mouse
14697704Stsl4_mSalmonella typhimurium susceptibility locus 4 (mouse)67710000090000000Mouse
13824985Alh1_mamplitude of lateral head displacement 1 (mouse)67800000097000000Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678629504121115387Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681500000102200000Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683713869147052561Mouse
11251720Ewc4_methanol withdrawal and consumption 4 (mouse)684122513118122513Mouse
1301687Mnic2_mmacronutrient intake (mouse)Not determined686806805113544602Mouse
1301744Hdlq11_mHDL QTL 11 (mouse)Not determined687503360121503555Mouse
1301262Gasa3_mgastritis type A susceptibility locus 3 (mouse)Not determined689005405123005603Mouse
15090872Cbcq2_mcecum bacterial composition QTL 2 (mouse)68921000089370000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1541
Count of miRNA genes:728
Interacting mature miRNAs:905
Transcripts:ENSMUST00000049845, ENSMUST00000163139
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000049845   ⟹   ENSMUSP00000063066
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl689,319,015 - 89,357,717 (-)Ensembl
RefSeq Acc Id: ENSMUST00000163139   ⟹   ENSMUSP00000131840
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl689,316,314 - 89,362,620 (-)Ensembl
RefSeq Acc Id: ENSMUST00000204468   ⟹   ENSMUSP00000144822
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl689,322,515 - 89,324,633 (-)Ensembl
RefSeq Acc Id: ENSMUST00000204997
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl689,330,378 - 89,333,070 (-)Ensembl
RefSeq Acc Id: ENSMUST00000205121   ⟹   ENSMUSP00000145403
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl689,335,411 - 89,342,591 (-)Ensembl
RefSeq Acc Id: ENSMUST00000205230
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl689,320,624 - 89,321,089 (-)Ensembl
RefSeq Acc Id: NM_008881   ⟹   NP_032907
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39689,293,295 - 89,339,595 (-)NCBI
GRCm38689,316,313 - 89,362,613 (-)ENTREZGENE
MGSCv37689,266,307 - 89,312,607 (-)RGD
Celera691,240,510 - 91,288,949 (-)RGD
cM Map6 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_032907   ⟸   NM_008881
- Peptide Label: precursor
- UniProtKB: P70206 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000131840   ⟸   ENSMUST00000163139
RefSeq Acc Id: ENSMUSP00000145403   ⟸   ENSMUST00000205121
RefSeq Acc Id: ENSMUSP00000144822   ⟸   ENSMUST00000204468
RefSeq Acc Id: ENSMUSP00000063066   ⟸   ENSMUST00000049845
Protein Domains
IPT/TIG   Sema

Promoters
RGD ID:6848020
Promoter ID:MM_ACW:41957
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour
Transcripts:PLXNA1.CSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36689,274,146 - 89,274,646 (-)MPROMDB
RGD ID:6848018
Promoter ID:MM_ACW:41959
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour
Transcripts:PLXNA1.BSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36689,292,546 - 89,293,046 (-)MPROMDB
RGD ID:6839758
Promoter ID:MM_KWN:46849
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Lung
Transcripts:NM_008881
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36689,312,446 - 89,313,397 (-)MPROMDB
RGD ID:6890396
Promoter ID:EPDNEW_M8649
Type:initiation region
Name:Plxna1_1
Description:Mus musculus plexin A1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38689,362,563 - 89,362,623EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:107685 AgrOrtholog
Ensembl Genes ENSMUSG00000030084 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000063066 UniProtKB/Swiss-Prot
  ENSMUSP00000131840 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000144822 UniProtKB/TrEMBL
  ENSMUSP00000145403 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000049845 UniProtKB/Swiss-Prot
  ENSMUST00000163139 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000204468 UniProtKB/TrEMBL
  ENSMUST00000205121 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot
  2.60.40.10 UniProtKB/Swiss-Prot
InterPro Ig-like_fold UniProtKB/Swiss-Prot
  Ig_E-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IPT_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Plexin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Plexin-A1_Sema UniProtKB/Swiss-Prot
  Plexin_cytoplasmic_RasGAP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Plexin_repeat UniProtKB/Swiss-Prot
  PSI UniProtKB/Swiss-Prot
  Rho_GTPase_activation_prot UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Semap_dom UniProtKB/Swiss-Prot
  Semap_dom_sf UniProtKB/Swiss-Prot
  TIG1_plexin UniProtKB/Swiss-Prot
  TIG2_plexin UniProtKB/Swiss-Prot
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot
KEGG Report mmu:18844 UniProtKB/Swiss-Prot
MGD MGI:107685 ENTREZGENE
NCBI Gene 18844 ENTREZGENE
PANTHER PTHR22625 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Plexin_cytopl UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PSI UniProtKB/Swiss-Prot
  Sema UniProtKB/Swiss-Prot
  TIG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIG_2 UniProtKB/Swiss-Prot
  TIG_plexin UniProtKB/Swiss-Prot
PhenoGen Plxna1 PhenoGen
PROSITE SEMA UniProtKB/Swiss-Prot
SMART IPT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PSI UniProtKB/Swiss-Prot
  Sema UniProtKB/Swiss-Prot
Superfamily-SCOP SSF101912 UniProtKB/Swiss-Prot
  SSF48350 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF81296 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0N4SUU1_MOUSE UniProtKB/TrEMBL
  A0A0N4SW74_MOUSE UniProtKB/TrEMBL
  P70206 ENTREZGENE, UniProtKB/Swiss-Prot
  Q3U3W7_MOUSE UniProtKB/TrEMBL
UniProt Secondary B2RQP7 UniProtKB/Swiss-Prot
  Q5DTR0 UniProtKB/Swiss-Prot