Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | SEMG1 | Human | 17beta-estradiol | multiple interactions | EXP | | 6480464 | Estradiol promotes the reaction [SEMG1 protein binds to ESR1 protein] | CTD | PMID:27156127 | SEMG1 | Human | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Semg1 (Mus musculus) | 6480464 | AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SEMG1 mRNA] | CTD | PMID:12151645 | SEMG1 | Human | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Semg1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SEMG1 mRNA | CTD | PMID:12151645 | SEMG1 | Human | 5-aza-2'-deoxycytidine | affects expression | EXP | | 6480464 | Decitabine affects the expression of SEMG1 mRNA and Decitabine affects the expression of SEMG1 protein | CTD | PMID:18468680 | SEMG1 | Human | aflatoxin B1 | decreases methylation | EXP | | 6480464 | Aflatoxin B1 results in decreased methylation of SEMG1 gene | CTD | PMID:27153756 | SEMG1 | Human | amiodarone | increases expression | EXP | | 6480464 | Amiodarone results in increased expression of SEMG1 mRNA | CTD | PMID:19774075 | SEMG1 | Human | ammonium chloride | affects expression | ISO | Semg1 (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of SEMG1 mRNA | CTD | PMID:16483693 | SEMG1 | Human | amphetamine | increases expression | ISO | Semg1 (Rattus norvegicus) | 6480464 | Amphetamine results in increased expression of SEMG1 mRNA | CTD | PMID:30779732 | SEMG1 | Human | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of SEMG1 mRNA | CTD | PMID:22316170 | SEMG1 | Human | benzo[a]pyrene | increases methylation | EXP | | 6480464 | Benzo(a)pyrene results in increased methylation of SEMG1 exon | CTD | PMID:27901495 | SEMG1 | Human | bisphenol A | increases methylation | ISO | Semg1 (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of SEMG1 gene | CTD | PMID:28505145 | SEMG1 | Human | bisphenol A | decreases expression | ISO | Semg1 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of SEMG1 mRNA | CTD | PMID:25181051 | SEMG1 | Human | carbamazepine | affects expression | EXP | | 6480464 | Carbamazepine affects the expression of SEMG1 mRNA | CTD | PMID:25979313 | SEMG1 | Human | chlordecone | increases expression | ISO | Semg1 (Mus musculus) | 6480464 | Chlordecone results in increased expression of SEMG1 mRNA | CTD | PMID:33711761 | SEMG1 | Human | decabromodiphenyl ether | decreases expression | ISO | Semg1 (Rattus norvegicus) | 6480464 | decabromobiphenyl ether results in decreased expression of SEMG1 mRNA | CTD | PMID:23640034 | SEMG1 | Human | hydroquinone O-beta-D-glucopyranoside | decreases expression | EXP | | 6480464 | Arbutin results in decreased expression of SEMG1 mRNA | CTD | PMID:17103032 | SEMG1 | Human | methotrexate | affects response to substance | EXP | | 6480464 | SEMG1 protein affects the susceptibility to Methotrexate | CTD | PMID:16217747 | SEMG1 | Human | N,N-diethyl-m-toluamide | multiple interactions | ISO | Semg1 (Rattus norvegicus) | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of SEMG1 gene | CTD | PMID:33148267 | SEMG1 | Human | okadaic acid | decreases expression | EXP | | 6480464 | Okadaic Acid results in decreased expression of SEMG1 protein | CTD | PMID:19397276 | SEMG1 | Human | permethrin | multiple interactions | ISO | Semg1 (Rattus norvegicus) | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of SEMG1 gene | CTD | PMID:33148267 | SEMG1 | Human | potassium dichromate | decreases expression | EXP | | 6480464 | Potassium Dichromate results in decreased expression of SEMG1 protein | CTD | PMID:23718831 | SEMG1 | Human | quartz | increases expression | EXP | | 6480464 | Quartz results in increased expression of SEMG1 mRNA | CTD | PMID:27917503 | SEMG1 | Human | silicon dioxide | increases expression | EXP | | 6480464 | Silicon Dioxide results in increased expression of SEMG1 mRNA | CTD | PMID:27917503 | SEMG1 | Human | silver atom | increases expression | ISO | Semg1 (Mus musculus) | 6480464 | Silver results in increased expression of SEMG1 mRNA | CTD | PMID:27131904 | SEMG1 | Human | silver(0) | increases expression | ISO | Semg1 (Mus musculus) | 6480464 | Silver results in increased expression of SEMG1 mRNA | CTD | PMID:27131904 | SEMG1 | Human | vinclozolin | decreases methylation | ISO | Semg1 (Rattus norvegicus) | 6480464 | vinclozolin results in decreased methylation of SEMG1 gene | CTD | PMID:31682807 | SEMG1 | Human | zinc atom | affects transport | EXP | | 6480464 | SEMG1 protein affects the transport of Zinc | CTD | PMID:17253191 | SEMG1 | Human | zinc atom | affects binding | EXP | | 6480464 | Zinc binds to SEMG1 protein | CTD | PMID:16582407 | SEMG1 | Human | zinc atom | multiple interactions | EXP | | 6480464 | SEMG1 protein inhibits the reaction [Zinc results in decreased activity of KLK5 protein] | CTD | PMID:16517595 | SEMG1 | Human | zinc(0) | affects transport | EXP | | 6480464 | SEMG1 protein affects the transport of Zinc | CTD | PMID:17253191 | SEMG1 | Human | zinc(0) | multiple interactions | EXP | | 6480464 | SEMG1 protein inhibits the reaction [Zinc results in decreased activity of KLK5 protein] | CTD | PMID:16517595 | SEMG1 | Human | zinc(0) | affects binding | EXP | | 6480464 | Zinc binds to SEMG1 protein | CTD | PMID:16582407 | |