MIR382 (microRNA 382) - Rat Genome Database

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Gene: MIR382 (microRNA 382) Homo sapiens
Analyze
Symbol: MIR382
Name: microRNA 382
RGD ID: 1343561
HGNC Page HGNC:31875
Description: Predicted to be involved in energy homeostasis and negative regulation of gene expression. Predicted to act upstream of or within several processes, including cellular response to leukemia inhibitory factor; cellular response to phenylalanine; and long-term synaptic potentiation. Predicted to be part of RISC complex.
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: hsa-mir-382; mir-382; MIRN382
RGD Orthologs
Mouse
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3814101,054,306 - 101,054,381 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl14101,054,306 - 101,054,381 (+)EnsemblGRCh38hg38GRCh38
GRCh3714101,520,643 - 101,520,718 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3614100,590,395 - 100,590,470 (+)NCBINCBI36Build 36hg18NCBI36
Celera1481,576,704 - 81,576,779 (+)NCBICelera
Cytogenetic Map14q32.31NCBI
HuRef1481,704,016 - 81,704,091 (+)NCBIHuRef
CHM1_114101,459,665 - 101,459,740 (+)NCBICHM1_1
T2T-CHM13v2.01495,289,690 - 95,289,765 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
RISC complex  (IEA)

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15891114   PMID:16274478   PMID:16381832   PMID:17604727   PMID:20716515   PMID:21037258   PMID:23542694   PMID:25064468   PMID:25265644   PMID:25292190   PMID:25344865   PMID:25677173  
PMID:26078564   PMID:26575700   PMID:26636539   PMID:26800338   PMID:27320691   PMID:27520398   PMID:27705918   PMID:27748848   PMID:28006750   PMID:28111007   PMID:28680529   PMID:28694664  
PMID:28813705   PMID:28871006   PMID:28901408   PMID:29487005   PMID:29700213   PMID:29790629   PMID:30417335   PMID:30453015   PMID:30474556   PMID:30825231   PMID:31144313   PMID:31364748  
PMID:31479715   PMID:31635836   PMID:31747371   PMID:32091151   PMID:32240747   PMID:32423803   PMID:32463333   PMID:32690086   PMID:32975076   PMID:33685351   PMID:34258298   PMID:34697393  
PMID:34898279   PMID:35066809   PMID:35500847   PMID:35593504   PMID:35655254   PMID:36069230   PMID:36162436   PMID:36894950   PMID:37788370   PMID:38214357  


Genomics

Comparative Map Data
MIR382
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3814101,054,306 - 101,054,381 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl14101,054,306 - 101,054,381 (+)EnsemblGRCh38hg38GRCh38
GRCh3714101,520,643 - 101,520,718 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3614100,590,395 - 100,590,470 (+)NCBINCBI36Build 36hg18NCBI36
Celera1481,576,704 - 81,576,779 (+)NCBICelera
Cytogenetic Map14q32.31NCBI
HuRef1481,704,016 - 81,704,091 (+)NCBIHuRef
CHM1_114101,459,665 - 101,459,740 (+)NCBICHM1_1
T2T-CHM13v2.01495,289,690 - 95,289,765 (+)NCBIT2T-CHM13v2.0
Mir382
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912109,700,205 - 109,700,280 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12109,700,205 - 109,700,280 (+)EnsemblGRCm39 Ensembl
GRCm3812109,733,771 - 109,733,846 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12109,733,771 - 109,733,846 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712110,971,981 - 110,972,056 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera12110,931,002 - 110,931,077 (+)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1260.56NCBI


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 14q32.2-32.33(chr14:99831655-106855263)x1 copy number loss See cases [RCV000133831] Chr14:99831655..106855263 [GRCh38]
Chr14:100297992..107263478 [GRCh37]
Chr14:99367745..106334523 [NCBI36]
Chr14:14q32.2-32.33		 pathogenic
GRCh38/hg38 14q24.3-32.33(chr14:73655772-106879298)x3 copy number gain See cases [RCV000134000] Chr14:73655772..106879298 [GRCh38]
Chr14:74122475..107287505 [GRCh37]
Chr14:73192228..106358550 [NCBI36]
Chr14:14q24.3-32.33		 pathogenic
GRCh38/hg38 14q32.2-32.33(chr14:100309382-105987610)x3 copy number gain See cases [RCV000135410] Chr14:100309382..105987610 [GRCh38]
Chr14:100775719..106453697 [GRCh37]
Chr14:99845472..105524742 [NCBI36]
Chr14:14q32.2-32.33		 pathogenic
GRCh38/hg38 14q32.2-32.33(chr14:97638520-106855263)x3 copy number gain See cases [RCV000135400] Chr14:97638520..106855263 [GRCh38]
Chr14:98104857..107263478 [GRCh37]
Chr14:97174610..106334523 [NCBI36]
Chr14:14q32.2-32.33		 pathogenic
GRCh38/hg38 14q32.2-32.33(chr14:99448012-106850609)x3 copy number gain See cases [RCV000135875] Chr14:99448012..106850609 [GRCh38]
Chr14:99914349..107258824 [GRCh37]
Chr14:98984102..106329869 [NCBI36]
Chr14:14q32.2-32.33		 pathogenic
GRCh38/hg38 14q11.2-32.33(chr14:20151149-106855263)x3 copy number gain See cases [RCV000135543] Chr14:20151149..106855263 [GRCh38]
Chr14:20619308..107263478 [GRCh37]
Chr14:19689148..106334523 [NCBI36]
Chr14:14q11.2-32.33		 pathogenic
GRCh38/hg38 14q32.12-32.33(chr14:92540983-104863658)x3 copy number gain See cases [RCV000135896] Chr14:92540983..104863658 [GRCh38]
Chr14:93007328..105329995 [GRCh37]
Chr14:92077081..104401040 [NCBI36]
Chr14:14q32.12-32.33		 pathogenic
GRCh38/hg38 14q32.13-32.33(chr14:95524407-106879501)x1 copy number loss See cases [RCV000136032] Chr14:95524407..106879501 [GRCh38]
Chr14:95990744..107287708 [GRCh37]
Chr14:95060497..106358753 [NCBI36]
Chr14:14q32.13-32.33		 pathogenic
GRCh38/hg38 14q24.3-32.33(chr14:77222795-106879298)x3 copy number gain See cases [RCV000138230] Chr14:77222795..106879298 [GRCh38]
Chr14:77689138..107287505 [GRCh37]
Chr14:76758891..106358550 [NCBI36]
Chr14:14q24.3-32.33		 pathogenic
GRCh38/hg38 14q32.2-32.31(chr14:100262836-102500697)x1 copy number loss See cases [RCV000139723] Chr14:100262836..102500697 [GRCh38]
Chr14:100729173..102967034 [GRCh37]
Chr14:99798926..102036787 [NCBI36]
Chr14:14q32.2-32.31		 pathogenic
GRCh38/hg38 14q11.2-32.33(chr14:20043514-106877229)x3 copy number gain See cases [RCV000143373] Chr14:20043514..106877229 [GRCh38]
Chr14:20511673..107285437 [GRCh37]
Chr14:19581513..106356482 [NCBI36]
Chr14:14q11.2-32.33		 pathogenic
GRCh38/hg38 14q32.2-32.33(chr14:100582059-106877229)x1 copy number loss See cases [RCV000143662] Chr14:100582059..106877229 [GRCh38]
Chr14:101048396..107285437 [GRCh37]
Chr14:100118149..106356482 [NCBI36]
Chr14:14q32.2-32.33		 pathogenic
NC_000014.9:g.100806482_101281031del474550 deletion Paternal uniparental disomy of chromosome 14 [RCV000149429] Chr14:100806482..101281031 [GRCh38]
Chr14:101272819..101747368 [GRCh37]
Chr14:14q32.2-32.31		 pathogenic
GRCh38/hg38 14q32.2-32.33(chr14:100590353-106855264)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051553]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051553]|See cases [RCV000051553] Chr14:100590353..106855264 [GRCh38]
Chr14:101056690..107263479 [GRCh37]
Chr14:100126443..106334524 [NCBI36]
Chr14:14q32.2-32.33		 pathogenic
GRCh38/hg38 14q32.2-32.33(chr14:97938637-106855263)x1 copy number loss See cases [RCV000050696] Chr14:97938637..106855263 [GRCh38]
Chr14:98404974..107263478 [GRCh37]
Chr14:97474727..106334523 [NCBI36]
Chr14:14q32.2-32.33		 pathogenic
GRCh38/hg38 14q32.2-32.33(chr14:100309382-106855263)x1 copy number loss See cases [RCV000050938] Chr14:100309382..106855263 [GRCh38]
Chr14:100775719..107263478 [GRCh37]
Chr14:99845472..106334523 [NCBI36]
Chr14:14q32.2-32.33		 pathogenic
GRCh38/hg38 14q32.2-32.33(chr14:100808300-106855263)x1 copy number loss See cases [RCV000051113] Chr14:100808300..106855263 [GRCh38]
Chr14:101274637..107263478 [GRCh37]
Chr14:100344390..106334523 [NCBI36]
Chr14:14q32.2-32.33		 pathogenic
GRCh38/hg38 14q31.2-32.33(chr14:83912345-106855405)x3 copy number gain See cases [RCV000052294] Chr14:83912345..106855405 [GRCh38]
Chr14:84378689..107263620 [GRCh37]
Chr14:83448442..106334665 [NCBI36]
Chr14:14q31.2-32.33		 pathogenic
GRCh38/hg38 14q31.3-32.33(chr14:86094030-106832642)x3 copy number gain See cases [RCV000052295] Chr14:86094030..106832642 [GRCh38]
Chr14:86560374..107240869 [GRCh37]
Chr14:85630127..106311914 [NCBI36]
Chr14:14q31.3-32.33		 pathogenic
GRCh38/hg38 14q32.12-32.33(chr14:91455861-106832642)x3 copy number gain See cases [RCV000052296] Chr14:91455861..106832642 [GRCh38]
Chr14:91922205..107240869 [GRCh37]
Chr14:90991958..106311914 [NCBI36]
Chr14:14q32.12-32.33		 pathogenic
GRCh38/hg38 14q32.13-32.33(chr14:94628219-106451054)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052298]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052298]|See cases [RCV000052298] Chr14:94628219..106451054 [GRCh38]
Chr14:95094556..106906960 [GRCh37]
Chr14:94164309..105978005 [NCBI36]
Chr14:14q32.13-32.33		 pathogenic
miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:24094
Count of gene targets:8857
Count of transcripts:17142
Interacting mature miRNAs:hsa-miR-382-3p, hsa-miR-382-5p
Prediction methods:Microtar, Miranda, Pita, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue appendage
High
Medium
Low 4 4 7 1 11 2 15 2 7 9
Below cutoff 3 1 2 1 5 3 11 1 1 2

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000637119
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl14101,054,306 - 101,054,381 (+)Ensembl
RefSeq Acc Id: NR_029874
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3814101,054,306 - 101,054,381 (+)NCBI
GRCh3714101,520,643 - 101,520,718 (+)RGD
Celera1481,576,704 - 81,576,779 (+)RGD
HuRef1481,704,016 - 81,704,091 (+)ENTREZGENE
CHM1_114101,459,665 - 101,459,740 (+)NCBI
T2T-CHM13v2.01495,289,690 - 95,289,765 (+)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:31875 AgrOrtholog
COSMIC MIR382 COSMIC
Ensembl Genes ENSG00000283170 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000637119 ENTREZGENE
GTEx ENSG00000283170 GTEx
HGNC ID HGNC:31875 ENTREZGENE
Human Proteome Map MIR382 Human Proteome Map
miRBase MI0000790 ENTREZGENE
NCBI Gene 494331 ENTREZGENE
PharmGKB PA164722701 PharmGKB
RNAcentral URS000013E79D RNACentral
  URS000035E174 RNACentral
  URS000075ABA3 RNACentral