Symbol:
MIR345
Name:
microRNA 345
RGD ID:
1343414
HGNC Page
HGNC:31779
Description:
Enables mRNA base-pairing translational repressor activity. Involved in miRNA-mediated gene silencing by inhibition of translation. Located in extracellular space.
Type:
ncrna (Ensembl: miRNA)
RefSeq Status:
PROVISIONAL
Previously known as:
hsa-mir-345; mir-345; MIRN345
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Allele / Splice:
See ClinVar data
Latest Assembly:
GRCh38 - Human Genome Assembly GRCh38
Position:
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 14 100,307,859 - 100,307,956 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 14 100,307,859 - 100,307,956 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 14 100,774,196 - 100,774,293 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 14 99,843,948 - 99,844,045 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Celera 14 80,828,823 - 80,828,920 (+) NCBI Celera Cytogenetic Map 14 q32.2 NCBI HuRef 14 80,955,554 - 80,955,651 (+) NCBI HuRef CHM1_1 14 100,711,974 - 100,712,071 (+) NCBI CHM1_1 T2T-CHM13v2.0 14 94,540,893 - 94,540,990 (+) NCBI T2T-CHM13v2.0
JBrowse:
View Region in Genome Browser (JBrowse)
Model
MIR345 Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 14 100,307,859 - 100,307,956 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 14 100,307,859 - 100,307,956 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 14 100,774,196 - 100,774,293 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 14 99,843,948 - 99,844,045 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Celera 14 80,828,823 - 80,828,920 (+) NCBI Celera Cytogenetic Map 14 q32.2 NCBI HuRef 14 80,955,554 - 80,955,651 (+) NCBI HuRef CHM1_1 14 100,711,974 - 100,712,071 (+) NCBI CHM1_1 T2T-CHM13v2.0 14 94,540,893 - 94,540,990 (+) NCBI T2T-CHM13v2.0
Mir345 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 12 108,802,899 - 108,802,994 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 12 108,802,899 - 108,802,994 (+) Ensembl GRCm39 Ensembl GRCm38 12 108,836,973 - 108,837,068 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 12 108,836,973 - 108,837,068 (+) Ensembl GRCm38 mm10 GRCm38 MGSCv37 12 110,075,183 - 110,075,278 (+) NCBI GRCm37 MGSCv37 mm9 NCBIm37 Celera 12 110,073,210 - 110,073,305 (+) NCBI Celera Cytogenetic Map 12 F1 NCBI cM Map 12 59.63 NCBI
Mir345 Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 6 133,518,403 - 133,518,498 (+) NCBI GRCr8 mRatBN7.2 6 127,754,027 - 127,754,122 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 6 127,754,027 - 127,754,122 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 6 127,877,034 - 127,877,129 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 6 128,172,080 - 128,172,175 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 6 127,531,453 - 127,531,548 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 6 132,748,968 - 132,749,063 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 6 132,748,968 - 132,749,063 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 6 141,919,044 - 141,919,139 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 Celera 6 125,304,925 - 125,305,020 (+) NCBI Celera Cytogenetic Map 6 q32 NCBI
MIR345 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 8 68,592,447 - 68,592,506 (+) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 8 68,111,175 - 68,111,234 (+) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 8 68,876,305 - 68,876,364 (+) NCBI ROS_Cfam_1.0 UMICH_Zoey_3.1 8 68,538,192 - 68,538,251 (+) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 8 68,604,329 - 68,604,388 (+) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 8 69,001,778 - 69,001,837 (+) NCBI UU_Cfam_GSD_1.0
MIR345-1 Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 7 121,193,716 - 121,193,799 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 7 121,193,720 - 121,193,799 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 7 128,658,300 - 128,658,379 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
.
Confirmed Targets
CDKN1A hsa-miR-345-5p Mirtarbase external_info qRT-PCR//Luciferase reporter assay//Western blot Functional MTI 20190813 ABCC1 hsa-miR-345-5p Mirtarbase external_info Luciferase reporter assay//Western blot Functional MTI 20099276 NTRK3 hsa-miR-345-5p Mirtarbase external_info Luciferase reporter assay Non-Functional MTI 19370765 MSH3 hsa-miR-345-5p Mirtarbase external_info CLASH Functional MTI (Weak) 23622248 BAG3 hsa-miR-345-5p OncomiRDB external_info NA NA 21665895 ABCC1 hsa-miR-345-5p OncomiRDB external_info NA NA 20099276
Predicted Targets
Count of predictions: 27085 Count of gene targets: 10376 Count of transcripts: 20560 Interacting mature miRNAs: hsa-miR-345-3p, hsa-miR-345-5p Prediction methods: Microtar, Miranda, Pita, Rnahybrid, Targetscan Result types: miRGate_prediction
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
entire extraembryonic component
10
116
45
42
296
210
334
3
44
142
42
111
400
249
34
205
102
207
270
7
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENST00000362114
Type:
CODING
Position:
Human Assembly Chr Position (strand) Source GRCh38.p14 Ensembl 14 100,307,859 - 100,307,956 (+) Ensembl
RefSeq Acc Id:
NR_029906
RefSeq Status:
PROVISIONAL
Type:
NON-CODING
Position:
Human Assembly Chr Position (strand) Source GRCh38 14 100,307,859 - 100,307,956 (+) NCBI GRCh37 14 100,774,196 - 100,774,293 (+) RGD Celera 14 80,828,823 - 80,828,920 (+) RGD HuRef 14 80,955,554 - 80,955,651 (+) ENTREZGENE CHM1_1 14 100,711,974 - 100,712,071 (+) NCBI T2T-CHM13v2.0 14 94,540,893 - 94,540,990 (+) NCBI
Sequence:
ACCCAAACCCTAGGTCTGCTGACTCCTAGTCCAGGGCTCGTGATGGCTGGTGGGCCCTGAACGAGGGGTCTGGAGGCCTGGGTTTGAATATCGACAGC
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