Eif2d (eukaryotic translation initiation factor 2D) - Rat Genome Database

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Gene: Eif2d (eukaryotic translation initiation factor 2D) Mus musculus
Analyze
Symbol: Eif2d
Name: eukaryotic translation initiation factor 2D
RGD ID: 1322884
MGI Page MGI
Description: Predicted to enable translation initiation factor activity. Predicted to be involved in IRES-dependent viral translational initiation; formation of translation preinitiation complex; and ribosome disassembly. Predicted to be located in cytosol and nuclear body. Predicted to be part of cytosolic small ribosomal subunit. Orthologous to human EIF2D (eukaryotic translation initiation factor 2D).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: D1Ertd5; D1Ertd5e; Lg; Lgtn; ligatin
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm4806  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
NCBI Annotation Information: Note: The name of this locus was changed from ligatin to eukaryotic translation initiation factor 2D based on the gene characterization of the human ortholog reported in PMID:20566627. [18 Aug 2011]
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391131,080,903 - 131,115,396 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1131,080,918 - 131,115,395 (+)EnsemblGRCm39 Ensembl
GRCm381131,153,172 - 131,187,659 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1131,153,181 - 131,187,658 (+)EnsemblGRCm38mm10GRCm38
MGSCv371133,049,784 - 133,070,048 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361132,980,782 - 132,999,780 (+)NCBIMGSCv36mm8
Celera1133,775,887 - 133,795,744 (+)NCBICelera
Cytogenetic Map1E4NCBI
cM Map156.9NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9070942   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:14610273   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:18799693  
PMID:21873635   PMID:30196744   PMID:32098917   PMID:38355793  


Genomics

Comparative Map Data
Eif2d
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391131,080,903 - 131,115,396 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1131,080,918 - 131,115,395 (+)EnsemblGRCm39 Ensembl
GRCm381131,153,172 - 131,187,659 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1131,153,181 - 131,187,658 (+)EnsemblGRCm38mm10GRCm38
MGSCv371133,049,784 - 133,070,048 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361132,980,782 - 132,999,780 (+)NCBIMGSCv36mm8
Celera1133,775,887 - 133,795,744 (+)NCBICelera
Cytogenetic Map1E4NCBI
cM Map156.9NCBI
EIF2D
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381206,569,146 - 206,612,465 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1206,571,292 - 206,612,465 (-)EnsemblGRCh38hg38GRCh38
GRCh371206,764,974 - 206,785,818 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361204,831,597 - 204,852,527 (-)NCBINCBI36Build 36hg18NCBI36
Build 341203,153,371 - 203,174,299NCBI
Celera1180,016,423 - 180,037,351 (-)NCBICelera
Cytogenetic Map1q32.1NCBI
HuRef1177,463,289 - 177,484,217 (-)NCBIHuRef
CHM1_11208,037,181 - 208,058,090 (-)NCBICHM1_1
T2T-CHM13v2.01205,827,369 - 205,876,640 (-)NCBIT2T-CHM13v2.0
Eif2d
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81345,168,161 - 45,189,362 (+)NCBIGRCr8
mRatBN7.21342,615,901 - 42,637,107 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1342,615,911 - 42,639,719 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1345,222,598 - 45,241,563 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01346,510,729 - 46,529,694 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01343,774,845 - 43,793,785 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01347,935,138 - 47,958,459 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1347,935,163 - 47,954,090 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01353,011,077 - 53,033,762 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41344,099,725 - 44,118,652 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1342,961,793 - 42,980,721 (+)NCBICelera
Cytogenetic Map13q13NCBI
Eif2d
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540642,163,632 - 42,181,337 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540642,163,508 - 42,181,482 (-)NCBIChiLan1.0ChiLan1.0
EIF2D
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2142,762,926 - 42,784,684 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1142,728,446 - 42,750,211 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01182,193,709 - 182,214,981 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11186,473,496 - 186,494,371 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1186,473,496 - 186,494,896 (-)Ensemblpanpan1.1panPan2
EIF2D
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1382,851,972 - 2,871,574 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl382,851,978 - 2,871,518 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha382,944,091 - 2,963,655 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0382,849,269 - 2,868,948 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl382,846,143 - 2,868,902 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1382,842,501 - 2,862,019 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0383,235,478 - 3,255,053 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0383,436,042 - 3,455,816 (-)NCBIUU_Cfam_GSD_1.0
Eif2d
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934468,725,272 - 68,745,708 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365575,965,504 - 5,986,064 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365575,965,496 - 5,985,993 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EIF2D
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl967,240,588 - 67,261,223 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1967,240,586 - 67,261,250 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2973,593,837 - 73,614,045 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EIF2D
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12522,752,852 - 22,773,566 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2522,752,926 - 22,773,568 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605523,451,194 - 23,471,916 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eif2d
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248074,818,585 - 4,836,280 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248074,818,652 - 4,834,898 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2795
Count of miRNA genes:844
Interacting mature miRNAs:1154
Transcripts:ENSMUST00000068791, ENSMUST00000068805, ENSMUST00000112446, ENSMUST00000131855, ENSMUST00000139468, ENSMUST00000149119, ENSMUST00000151874, ENSMUST00000153651
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27095901Scvln8_msacral vertebrae length 2, 10 week (mouse)194127725172027567Mouse
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
1302098Eila1_methanol induced locomotor activity 1 (mouse)Not determined1112008822175468938Mouse
1302161Exq2_mexploratory and excitability QTL 2 (mouse)Not determined1118099720152099816Mouse
1357847Jckm2_mjuvenile cystic kidney modifier 2 (mouse)Not determined174991977133290937Mouse
27226779Tibl1_mtibia length 1, 5 week (mouse)195527725162027569Mouse
27226714Metcl1_mmetatarsal-calcaneal length 1, 5 week (mouse)1121727729139727738Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163854690189303617Mouse
1301979Melm1_mmelanoma modifier 1 (mouse)Not determined1109638262143638479Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145783900189303617Mouse
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
1301149Lrnx12_mlearning-contextual 12 (mouse)Not determined1112008822168186402Mouse
27226767Tibl10_mtibia length 10, 10 week (mouse)1121727729164827569Mouse
10045640Jckm4_mjuvenile cystic kidney modifier 4 (mouse)Not determined1116290836150290937Mouse
12790994Aaaq1_maortic arch angle QTL 1 (mouse)1109495943143495943Mouse
1301249Sbw1_msplenomegaly-NZB x NZW 1 (mouse)Not determined1112131005146131085Mouse
1301193Lxw3_mlupus BXSB x NZW 3 (mouse)Not determined1102968534136968667Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134760138150193871Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1103933405191225397Mouse
12880408V125Dq3_mvitamin D active form serum level QTL 3 (mouse)1122927738156927738Mouse
27095935Ulnl5_mulna length 5, 10 week (mouse)1128727737181327565Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134760138150193871Mouse
4141914Gcsfis_mG-CSF induced splenomegaly (mouse)Not determined74516235148715579Mouse
27095928Pglq6_mpelvic girdle length QTL 6, 10 week (mouse)175976637148775742Mouse
27226743Metcl7_mmetatarsal-calcaneal length 7, 10 week (mouse)1121727729153875746Mouse
1357439Popoa_mpremature ovulation and primary oocyte arrest (mouse)Not determined182643189135615379Mouse
27226740Metcl13_mmetatarsal-calcaneal length 13, 16 week (mouse)1121727729153775746Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52457737182250592Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134760138150193871Mouse
1300989Lrdg1_mlight induced retinal degeneration 1 (mouse)Not determined173755175147125370Mouse
27226799Feml5_mfemur length 5, 5 week (mouse)1122027729164827569Mouse
1301536Pbbcp1_mperipheral blood B cell percentage 1 (mouse)Not determined199507660133507845Mouse
1357600Obq17_mobesity QTL 17 (mouse)Not determined1110553179144553298Mouse
27095913Scvln2_msacral vertebrae length 2, 5 week (mouse)194127725148775742Mouse
1301350Nidd4k_mNidd4 on KK-A (mouse)Not determined782291982147125370Mouse
27095915Scvln13_msacral vertebrae length 2, 16 week (mouse)1117527730179827565Mouse
1300841Ssial1_msusceptibility to sialadenitis 1 (mouse)Not determined163920002153557562Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)175976637181327565Mouse
1301608Emo3_memotionality 3 (mouse)Not determined1129130858163130993Mouse
10401248Bglu12_mblood glucose level 12 (mouse)Not determined1110553179144553298Mouse

Markers in Region
D1Ertd5e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381131,158,137 - 131,158,384UniSTSGRCm38
MGSCv371133,054,714 - 133,054,961UniSTSGRCm37
Celera1133,780,874 - 133,781,121UniSTS
Cytogenetic Map1FUniSTS
cM Map156.9UniSTS
cM Map169.1UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001136070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001420301 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001420302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001420309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001420313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001420320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001420322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001420323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001420324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006529165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006529166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006529167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011247928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011247929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017318536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017318549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030251679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003953306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004940652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_387149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC109262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK030312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK034115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK036154 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK046539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK047005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK082748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK139052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK193013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC023709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC024501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC025036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ066870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U58337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000068791   ⟹   ENSMUSP00000067461
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1131,080,918 - 131,108,143 (+)Ensembl
GRCm38.p6 Ensembl1131,153,181 - 131,180,406 (+)Ensembl
Ensembl Acc Id: ENSMUST00000068805   ⟹   ENSMUSP00000063894
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1131,080,918 - 131,101,215 (+)Ensembl
GRCm38.p6 Ensembl1131,153,181 - 131,173,478 (+)Ensembl
Ensembl Acc Id: ENSMUST00000112446   ⟹   ENSMUSP00000108065
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1131,080,918 - 131,099,976 (+)Ensembl
GRCm38.p6 Ensembl1131,153,181 - 131,172,239 (+)Ensembl
Ensembl Acc Id: ENSMUST00000131855   ⟹   ENSMUSP00000137678
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1131,080,918 - 131,115,395 (+)Ensembl
GRCm38.p6 Ensembl1131,153,181 - 131,187,658 (+)Ensembl
Ensembl Acc Id: ENSMUST00000139468
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1131,080,918 - 131,086,639 (+)Ensembl
GRCm38.p6 Ensembl1131,153,181 - 131,158,902 (+)Ensembl
Ensembl Acc Id: ENSMUST00000149119   ⟹   ENSMUSP00000137887
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1131,080,918 - 131,102,589 (+)Ensembl
GRCm38.p6 Ensembl1131,153,181 - 131,174,852 (+)Ensembl
Ensembl Acc Id: ENSMUST00000151874   ⟹   ENSMUSP00000138061
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1131,080,918 - 131,107,729 (+)Ensembl
GRCm38.p6 Ensembl1131,153,181 - 131,179,992 (+)Ensembl
Ensembl Acc Id: ENSMUST00000153651
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1131,094,116 - 131,099,247 (+)Ensembl
GRCm38.p6 Ensembl1131,166,379 - 131,171,510 (+)Ensembl
RefSeq Acc Id: NM_001136070   ⟹   NP_001129542
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391131,080,933 - 131,101,235 (+)NCBI
GRCm381131,153,207 - 131,173,471 (+)NCBI
MGSCv371133,049,784 - 133,070,048 (+)RGD
Celera1133,775,887 - 133,795,744 (+)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001420301   ⟹   NP_001407230
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391131,080,933 - 131,104,400 (+)NCBI
RefSeq Acc Id: NM_001420302   ⟹   NP_001407231
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391131,080,933 - 131,108,143 (+)NCBI
RefSeq Acc Id: NM_001420309   ⟹   NP_001407238
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391131,080,933 - 131,101,235 (+)NCBI
RefSeq Acc Id: NM_001420313   ⟹   NP_001407242
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391131,080,933 - 131,101,235 (+)NCBI
RefSeq Acc Id: NM_001420320   ⟹   NP_001407249
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391131,080,933 - 131,101,235 (+)NCBI
RefSeq Acc Id: NM_001420322   ⟹   NP_001407251
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391131,080,933 - 131,101,235 (+)NCBI
RefSeq Acc Id: NM_001420323   ⟹   NP_001407252
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391131,080,933 - 131,101,235 (+)NCBI
RefSeq Acc Id: NM_001420324   ⟹   NP_001407253
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391131,080,933 - 131,101,235 (+)NCBI
RefSeq Acc Id: NM_010709   ⟹   NP_034839
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391131,080,933 - 131,099,975 (+)NCBI
GRCm381131,153,207 - 131,172,234 (+)NCBI
MGSCv371133,049,784 - 133,070,048 (+)RGD
Celera1133,775,887 - 133,795,744 (+)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006529165   ⟹   XP_006529228
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391131,080,903 - 131,115,396 (+)NCBI
GRCm381131,153,172 - 131,187,659 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006529166   ⟹   XP_006529229
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391131,080,903 - 131,108,143 (+)NCBI
GRCm381131,153,172 - 131,180,406 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006529167   ⟹   XP_006529230
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391131,080,903 - 131,115,396 (+)NCBI
GRCm381131,153,172 - 131,187,659 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011247928   ⟹   XP_011246230
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391131,080,903 - 131,108,143 (+)NCBI
GRCm381131,153,172 - 131,180,406 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011247929   ⟹   XP_011246231
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391131,080,909 - 131,115,396 (+)NCBI
GRCm381131,153,172 - 131,187,659 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017318536   ⟹   XP_017174025
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391131,080,903 - 131,108,143 (+)NCBI
GRCm381131,153,172 - 131,180,406 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017318549   ⟹   XP_017174038
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391131,080,909 - 131,107,731 (+)NCBI
GRCm381131,153,172 - 131,173,501 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030251679   ⟹   XP_030107539
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391131,080,909 - 131,100,361 (+)NCBI
GRCm381131,153,172 - 131,172,624 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036162349   ⟹   XP_036018242
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391131,080,909 - 131,108,143 (+)NCBI
Sequence:
RefSeq Acc Id: XR_003953306
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391131,080,903 - 131,107,731 (+)NCBI
GRCm381131,153,172 - 131,174,162 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004940652
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391131,080,903 - 131,100,361 (+)NCBI
Sequence:
RefSeq Acc Id: XR_387149
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391131,080,903 - 131,107,731 (+)NCBI
GRCm381131,153,172 - 131,174,162 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001129542 (Get FASTA)   NCBI Sequence Viewer  
  NP_001407230 (Get FASTA)   NCBI Sequence Viewer  
  NP_001407231 (Get FASTA)   NCBI Sequence Viewer  
  NP_001407238 (Get FASTA)   NCBI Sequence Viewer  
  NP_001407242 (Get FASTA)   NCBI Sequence Viewer  
  NP_001407249 (Get FASTA)   NCBI Sequence Viewer  
  NP_001407251 (Get FASTA)   NCBI Sequence Viewer  
  NP_001407252 (Get FASTA)   NCBI Sequence Viewer  
  NP_001407253 (Get FASTA)   NCBI Sequence Viewer  
  NP_034839 (Get FASTA)   NCBI Sequence Viewer  
  XP_006529228 (Get FASTA)   NCBI Sequence Viewer  
  XP_006529229 (Get FASTA)   NCBI Sequence Viewer  
  XP_006529230 (Get FASTA)   NCBI Sequence Viewer  
  XP_011246230 (Get FASTA)   NCBI Sequence Viewer  
  XP_011246231 (Get FASTA)   NCBI Sequence Viewer  
  XP_017174025 (Get FASTA)   NCBI Sequence Viewer  
  XP_017174038 (Get FASTA)   NCBI Sequence Viewer  
  XP_030107539 (Get FASTA)   NCBI Sequence Viewer  
  XP_036018242 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC53056 (Get FASTA)   NCBI Sequence Viewer  
  AAH24501 (Get FASTA)   NCBI Sequence Viewer  
  AAH25036 (Get FASTA)   NCBI Sequence Viewer  
  BAC28591 (Get FASTA)   NCBI Sequence Viewer  
  BAC29323 (Get FASTA)   NCBI Sequence Viewer  
  BAC32777 (Get FASTA)   NCBI Sequence Viewer  
  BAC32939 (Get FASTA)   NCBI Sequence Viewer  
  BAC38598 (Get FASTA)   NCBI Sequence Viewer  
  BAC38976 (Get FASTA)   NCBI Sequence Viewer  
  BAE23874 (Get FASTA)   NCBI Sequence Viewer  
  BAE36281 (Get FASTA)   NCBI Sequence Viewer  
  BAE39972 (Get FASTA)   NCBI Sequence Viewer  
  BAE40091 (Get FASTA)   NCBI Sequence Viewer  
  BAE41662 (Get FASTA)   NCBI Sequence Viewer  
  BAE41806 (Get FASTA)   NCBI Sequence Viewer  
  BAE42257 (Get FASTA)   NCBI Sequence Viewer  
  EDL39715 (Get FASTA)   NCBI Sequence Viewer  
  EDL39716 (Get FASTA)   NCBI Sequence Viewer  
  EDL39717 (Get FASTA)   NCBI Sequence Viewer  
  EDL39718 (Get FASTA)   NCBI Sequence Viewer  
  EDL39719 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000063894
  ENSMUSP00000063894.8
  ENSMUSP00000067461
  ENSMUSP00000067461.5
  ENSMUSP00000108065
  ENSMUSP00000108065.3
  ENSMUSP00000137678
  ENSMUSP00000137678.2
  ENSMUSP00000137887.2
  ENSMUSP00000138061
  ENSMUSP00000138061.2
GenBank Protein Q61211 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_034839   ⟸   NM_010709
- Peptide Label: isoform 2
- UniProtKB: E9PUG7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001129542   ⟸   NM_001136070
- Peptide Label: isoform 1
- UniProtKB: Q8R1I9 (UniProtKB/Swiss-Prot),   Q8CC17 (UniProtKB/Swiss-Prot),   Q8CBF1 (UniProtKB/Swiss-Prot),   Q8C491 (UniProtKB/Swiss-Prot),   Q3TTP4 (UniProtKB/Swiss-Prot),   Q3THV5 (UniProtKB/Swiss-Prot),   Q3TDE0 (UniProtKB/Swiss-Prot),   Q8R3M5 (UniProtKB/Swiss-Prot),   Q61211 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006529228   ⟸   XM_006529165
- Peptide Label: isoform X1
- UniProtKB: A0A0R4J298 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006529230   ⟸   XM_006529167
- Peptide Label: isoform X4
- UniProtKB: Q8C8I3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006529229   ⟸   XM_006529166
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011246230   ⟸   XM_011247928
- Peptide Label: isoform X3
- UniProtKB: Q8C8I3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011246231   ⟸   XM_011247929
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_017174025   ⟸   XM_017318536
- Peptide Label: isoform X6
- UniProtKB: Q8C8I3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017174038   ⟸   XM_017318549
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_030107539   ⟸   XM_030251679
- Peptide Label: isoform X10
Ensembl Acc Id: ENSMUSP00000067461   ⟸   ENSMUST00000068791
Ensembl Acc Id: ENSMUSP00000063894   ⟸   ENSMUST00000068805
Ensembl Acc Id: ENSMUSP00000108065   ⟸   ENSMUST00000112446
Ensembl Acc Id: ENSMUSP00000138061   ⟸   ENSMUST00000151874
Ensembl Acc Id: ENSMUSP00000137678   ⟸   ENSMUST00000131855
Ensembl Acc Id: ENSMUSP00000137887   ⟸   ENSMUST00000149119
RefSeq Acc Id: XP_036018242   ⟸   XM_036162349
- Peptide Label: isoform X9
RefSeq Acc Id: NP_001407231   ⟸   NM_001420302
- Peptide Label: isoform 1
- UniProtKB: Q8R3M5 (UniProtKB/Swiss-Prot),   Q8R1I9 (UniProtKB/Swiss-Prot),   Q8CC17 (UniProtKB/Swiss-Prot),   Q8CBF1 (UniProtKB/Swiss-Prot),   Q8C491 (UniProtKB/Swiss-Prot),   Q61211 (UniProtKB/Swiss-Prot),   Q3TTP4 (UniProtKB/Swiss-Prot),   Q3THV5 (UniProtKB/Swiss-Prot),   Q3TDE0 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001407230   ⟸   NM_001420301
- Peptide Label: isoform 1
- UniProtKB: Q3TTP4 (UniProtKB/Swiss-Prot),   Q3THV5 (UniProtKB/Swiss-Prot),   Q3TDE0 (UniProtKB/Swiss-Prot),   Q8R3M5 (UniProtKB/Swiss-Prot),   Q8R1I9 (UniProtKB/Swiss-Prot),   Q8CC17 (UniProtKB/Swiss-Prot),   Q8CBF1 (UniProtKB/Swiss-Prot),   Q8C491 (UniProtKB/Swiss-Prot),   Q61211 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001407251   ⟸   NM_001420322
- Peptide Label: isoform 6
RefSeq Acc Id: NP_001407238   ⟸   NM_001420309
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001407252   ⟸   NM_001420323
- Peptide Label: isoform 7
RefSeq Acc Id: NP_001407249   ⟸   NM_001420320
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001407253   ⟸   NM_001420324
- Peptide Label: isoform 8
RefSeq Acc Id: NP_001407242   ⟸   NM_001420313
- Peptide Label: isoform 4
Protein Domains
DM2   PUA   SUI1   SWIB/MDM2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q61211-F1-model_v2 AlphaFold Q61211 1-570 view protein structure

Promoters
RGD ID:6874852
Promoter ID:EPDNEW_M877
Type:initiation region
Name:Eif2d_1
Description:Mus musculus eukaryotic translation initiation factor 2D , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381131,153,196 - 131,153,256EPDNEW
RGD ID:6818018
Promoter ID:MM_KWN:2025
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000086578,   OTTMUST00000051117,   OTTMUST00000051118,   OTTMUST00000051119,   OTTMUST00000051120,   OTTMUST00000051121,   OTTMUST00000051122,   OTTMUST00000051124
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361133,049,531 - 133,050,031 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:109342 AgrOrtholog
Ensembl Genes ENSMUSG00000026427 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000068791 ENTREZGENE
  ENSMUST00000068791.11 UniProtKB/TrEMBL
  ENSMUST00000068805 ENTREZGENE
  ENSMUST00000068805.14 UniProtKB/Swiss-Prot
  ENSMUST00000112446 ENTREZGENE
  ENSMUST00000112446.9 UniProtKB/TrEMBL
  ENSMUST00000131855 ENTREZGENE
  ENSMUST00000131855.2 UniProtKB/TrEMBL
  ENSMUST00000149119.8 UniProtKB/TrEMBL
  ENSMUST00000151874 ENTREZGENE
  ENSMUST00000151874.8 UniProtKB/Swiss-Prot
Gene3D-CATH 3.10.400.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SUI1-like domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro EIF2D UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  eIF2D_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  eIF2D_SUI1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pre-PUA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PUA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PUA-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PUA_eIF2d-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SUI1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SUI1_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SWIB_MDM2_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SWIB_MDM2_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Uncharacterised_CHP00451 UniProtKB/TrEMBL
KEGG Report mmu:16865 UniProtKB/Swiss-Prot
MGD MGI:109342 ENTREZGENE
NCBI Gene 16865 ENTREZGENE
PANTHER EUKARYOTIC TRANSLATION INITIATION FACTOR 2D UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12217 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Pre-PUA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SUI1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Eif2d PhenoGen
PROSITE PUA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SUI1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SWIB_MDM2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PUA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47592 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55159 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF88697 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J298 ENTREZGENE, UniProtKB/TrEMBL
  E9PUG7 ENTREZGENE, UniProtKB/TrEMBL
  EIF2D_MOUSE UniProtKB/Swiss-Prot
  M0QWK9_MOUSE UniProtKB/TrEMBL
  Q3TDE0 ENTREZGENE
  Q3THV5 ENTREZGENE
  Q3TTP4 ENTREZGENE
  Q61211 ENTREZGENE
  Q8C491 ENTREZGENE
  Q8C8I3 ENTREZGENE, UniProtKB/TrEMBL
  Q8CBF1 ENTREZGENE
  Q8CC17 ENTREZGENE
  Q8R1I9 ENTREZGENE
  Q8R3M5 ENTREZGENE
UniProt Secondary Q3TDE0 UniProtKB/Swiss-Prot
  Q3THV5 UniProtKB/Swiss-Prot
  Q3TTP4 UniProtKB/Swiss-Prot
  Q8C491 UniProtKB/Swiss-Prot
  Q8CBF1 UniProtKB/Swiss-Prot
  Q8CC17 UniProtKB/Swiss-Prot
  Q8R1I9 UniProtKB/Swiss-Prot
  Q8R3M5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-27 Eif2d  eukaryotic translation initiation factor 2D  Lgtn  ligatin  Symbol and/or name change 5135510 APPROVED