Alyref (Aly/REF export factor) - Rat Genome Database

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Gene: Alyref (Aly/REF export factor) Mus musculus
Analyze
Symbol: Alyref
Name: Aly/REF export factor
RGD ID: 1322670
MGI Page MGI
Description: Enables several functions, including RNA binding activity; RNA folding chaperone; and single-stranded DNA binding activity. Predicted to be involved in mRNA export from nucleus. Predicted to be located in cytoplasm. Predicted to be part of catalytic step 2 spliceosome; exon-exon junction complex; and transcription export complex. Predicted to be active in nucleus. Predicted to colocalize with chromosome, telomeric region. Is expressed in several structures, including branchial arch; central nervous system; future brain; genitourinary system; and sensory organ. Orthologous to human ALYREF (Aly/REF export factor).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ally of AML-1 and LEF-1; ALY; REF; REF1; REF1-I; Refb; Refbp1; RNA and export factor binding protein 1; RNA and export factor-binding protein 1; Tcra enhancer-binding factor interacting protein 1; THO complex 4; THO complex subunit 4; tho4; Thoc; Thoc4; transcriptional coactivator Aly/REF
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Alyreffm12   Alyreffm3   Gm4310   Gm4781   Gm4850   Gm4898   Gm5699   Gm8384   Gm8391   Gm8689   Gm8701   Gm8711   Gm8723   Gm9476  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911120,485,330 - 120,489,342 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11120,482,947 - 120,489,191 (-)EnsemblGRCm39 Ensembl
GRCm3811120,594,504 - 120,598,399 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11120,592,121 - 120,598,365 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711120,455,830 - 120,459,679 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611120,410,606 - 120,414,455 (-)NCBIMGSCv36mm8
Celera11132,329,807 - 132,333,656 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1184.31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
AlyrefMousebasal cell carcinoma  ISOALYREF (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:36428691
AlyrefMousehuman immunodeficiency virus infectious disease  ISOALYREF (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:15308739

1 to 20 of 96 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
AlyrefMouse(+)-schisandrin B multiple interactionsISOAlyref (Rattus norvegicus)6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of ALYREF mRNA]CTDPMID:31150632
AlyrefMouse1,2-dimethylhydrazine multiple interactionsEXP 6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ALYREF mRNACTDPMID:22206623
AlyrefMouse17beta-estradiol increases expressionISOAlyref (Rattus norvegicus)6480464Estradiol results in increased expression of ALYREF mRNACTDPMID:32145629
AlyrefMouse17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of ALYREF mRNACTDPMID:39298647
AlyrefMouse17beta-hydroxy-5alpha-androstan-3-one increases expressionEXP 6480464Dihydrotestosterone results in increased expression of ALYREF mRNACTDPMID:17023530
AlyrefMouse2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of ALYREF mRNACTDPMID:21570461
AlyrefMouse2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOAlyref (Rattus norvegicus)6480464Tetrachlorodibenzodioxin results in decreased expression of ALYREF mRNACTDPMID:34747641
AlyrefMouse3,4-methylenedioxymethamphetamine decreases expressionEXP 6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of ALYREF mRNACTDPMID:20188158
AlyrefMouse3,4-methylenedioxymethamphetamine increases expressionEXP 6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of ALYREF mRNACTDPMID:20188158
AlyrefMouse3-isobutyl-1-methyl-7H-xanthine multiple interactionsISOALYREF (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of ALYREF mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of ALYREF mRNACTDPMID:28628672
AlyrefMouse4,4'-sulfonyldiphenol multiple interactionsISOALYREF (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of ALYREF mRNACTDPMID:28628672
AlyrefMouse4,4'-sulfonyldiphenol increases expressionISOALYREF (Homo sapiens)6480464bisphenol S results in increased expression of ALYREF mRNA and bisphenol S results in increased expression of ALYREF proteinCTDPMID:34186270 and PMID:38568856
AlyrefMouse4,4'-sulfonyldiphenol increases expressionEXP 6480464bisphenol S results in increased expression of ALYREF mRNACTDPMID:39298647
AlyrefMouse6-propyl-2-thiouracil increases expressionISOAlyref (Rattus norvegicus)6480464Propylthiouracil results in increased expression of THOC4 mRNACTDPMID:24780913
AlyrefMouseacrylamide decreases expressionISOAlyref (Rattus norvegicus)6480464Acrylamide results in decreased expression of THOC4 mRNACTDPMID:28959563
AlyrefMouseactinomycin D multiple interactionsISOALYREF (Homo sapiens)6480464[Dactinomycin co-treated with nutlin 3] results in increased secretion of ALYREF proteinCTDPMID:38460933
AlyrefMouseamitrole decreases expressionISOAlyref (Rattus norvegicus)6480464Amitrole results in decreased expression of ALYREF mRNACTDPMID:38685447
AlyrefMouseatrazine decreases expressionISOALYREF (Homo sapiens)6480464Atrazine results in decreased expression of THOC4 mRNACTDPMID:22378314
AlyrefMousebenzo[a]pyrene decreases expressionEXP 6480464Benzo(a)pyrene results in decreased expression of ALYREF mRNACTDPMID:20504355
AlyrefMousebis(2-chloroethyl) sulfide increases expressionEXP 6480464Mustard Gas results in increased expression of ALYREF mRNACTDPMID:15674843

1 to 20 of 96 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
AlyrefMousemRNA export from nucleus involved_inISOUniProtKB:Q86V812290270 GO_CentralGO_REF:0000119
AlyrefMousemRNA export from nucleus involved_inIBAPANTHER:PTN000462807 more ...2290270 GO_CentralGO_REF:0000033
AlyrefMousemRNA processing involved_inIEAUniProtKB-KW:KW-05072290270 UniProtGO_REF:0000043
AlyrefMousemRNA transport involved_inIEAUniProtKB-KW:KW-05092290270 UniProtGO_REF:0000043
AlyrefMouseRNA export from nucleus involved_inISOUniProtKB:Q86V812290270 GO_CentralGO_REF:0000119
AlyrefMouseRNA export from nucleus involved_inISSUniProtKB:Q86V812290270 UniProtGO_REF:0000024
AlyrefMouseRNA folding involved_inIEAGO:01406912290270 GOCGO_REF:0000108
AlyrefMouseRNA splicing involved_inIEAUniProtKB-KW:KW-05082290270 UniProtGO_REF:0000043

Cellular Component
1 to 13 of 13 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
AlyrefMousecatalytic step 2 spliceosome part_ofISOUniProtKB:Q86V812290270 GO_CentralGO_REF:0000119
AlyrefMousechromosome, telomeric region located_inISOUniProtKB:Q86V812290270 GO_CentralGO_REF:0000119
AlyrefMousecytoplasm located_inISOUniProtKB:Q86V812290270 GO_CentralGO_REF:0000119
AlyrefMousecytoplasm located_inISSUniProtKB:Q86V812290270 UniProtGO_REF:0000024
AlyrefMouseexon-exon junction complex located_inISOALYREF (Homo sapiens)9068941 PMID:16314458UniProtPMID:16314458
AlyrefMouseexon-exon junction complex part_ofISOUniProtKB:Q86V812290270 GO_CentralGO_REF:0000119
AlyrefMousenuclear speck located_inIEAUniProtKB-SubCell:SL-01862290270 UniProtGO_REF:0000044
AlyrefMousenucleus located_inISSUniProtKB:Q86V812290270 UniProtGO_REF:0000024
AlyrefMousenucleus located_inTAS 2290270 PMID:10786854MGIPMID:10786854
AlyrefMousenucleus located_inISOUniProtKB:Q86V812290270 GO_CentralGO_REF:0000119
AlyrefMousenucleus is_active_inIBAPANTHER:PTN000462807 more ...2290270 GO_CentralGO_REF:0000033
AlyrefMousespliceosomal complex part_ofIEAUniProtKB-KW:KW-07472290270 UniProtGO_REF:0000043
AlyrefMousetranscription export complex part_ofISOUniProtKB:Q86V812290270 GO_CentralGO_REF:0000119
1 to 13 of 13 rows

Molecular Function
1 to 17 of 17 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
AlyrefMouseC5-methylcytidine-containing RNA reader activity enablesISOUniProtKB:Q86V812290270 GO_CentralGO_REF:0000119
AlyrefMouseC5-methylcytidine-containing RNA reader activity enablesISSUniProtKB:Q86V812290270 UniProtGO_REF:0000024
AlyrefMousemolecular adaptor activity enablesEXP 2290270 PMID:12809490DisProtPMID:12809490
AlyrefMousemRNA binding enablesIBAPANTHER:PTN000462807 more ...2290270 GO_CentralGO_REF:0000033
AlyrefMouseprotein binding enablesISOUniProtKB:Q091619068941 PMID:17190602UniProtPMID:17190602
AlyrefMouseprotein binding enablesISOUniProtKB:Q13838 more ...9068941 PMID:23299939IntActPMID:23299939
AlyrefMouseprotein binding enablesISOUniProtKB:Q01780 and UniProtKB:Q96ST29068941 PMID:17234882UniProtPMID:17234882
AlyrefMouseprotein binding enablesISOUniProtKB:Q9UBU99068941 PMID:11546874IntActPMID:11546874
AlyrefMouseprotein binding enablesISOUniProtKB:O00148 and UniProtKB:Q138389068941 PMID:15047853UniProtPMID:15047853
AlyrefMouseprotein binding enablesISOUniProtKB:Q13769 and UniProtKB:Q9UBU99068941 PMID:19165146UniProtPMID:19165146
AlyrefMouseprotein binding enablesISOUniProtKB:P064939068941 PMID:29128334IntActPMID:29128334
AlyrefMouseprotein binding enablesISOUniProtKB:Q2HR759068941 PMID:19850040 and PMID:21814512IntActPMID:19850040 and PMID:21814512
AlyrefMouseprotein binding enablesISOUniProtKB:P317499068941 PMID:18562279IntActPMID:18562279
AlyrefMouseprotein binding enablesISOUniProtKB:Q138389068941 PMID:11979277 more ...IntActPMID:11979277 more ...
AlyrefMouseRNA binding enablesIDA 2290270 PMID:10786854MGIPMID:10786854
AlyrefMouseRNA folding chaperone enablesEXP 2290270 PMID:12809490DisProtPMID:12809490
AlyrefMousesingle-stranded DNA binding enablesIDA 2290270 PMID:10786854MGIPMID:10786854
1 to 17 of 17 rows

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
AlyrefMouseNXF1-NXT1 export pathway  ISOALYREF (Homo sapiens)9743960 RGD 

#
Reference Title
Reference Citation
1. mRNA export and the TREX complex. Katahira J Biochim Biophys Acta. 2012 Jun;1819(6):507-13. doi: 10.1016/j.bbagrm.2011.12.001. Epub 2011 Dec 8.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:9119228   PMID:10349636   PMID:10786854   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12093754   PMID:12477932   PMID:12809490   PMID:14610273   PMID:14681479   PMID:15520881  
PMID:16033648   PMID:16141072   PMID:16141073   PMID:16679559   PMID:16971461   PMID:18495661   PMID:18799693   PMID:20059953   PMID:21122108   PMID:21267068   PMID:21873635   PMID:22922362  
PMID:23180766   PMID:24146773   PMID:24457600   PMID:26370502   PMID:27561680   PMID:28671696   PMID:29459677   PMID:29530978   PMID:30196744   PMID:30595499   PMID:30846735   PMID:31138677  
PMID:31598710   PMID:32098917   PMID:32325033   PMID:32434143   PMID:33548738   PMID:34321999   PMID:37640449   PMID:38331934  



Alyref
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911120,485,330 - 120,489,342 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11120,482,947 - 120,489,191 (-)EnsemblGRCm39 Ensembl
GRCm3811120,594,504 - 120,598,399 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11120,592,121 - 120,598,365 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711120,455,830 - 120,459,679 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611120,410,606 - 120,414,455 (-)NCBIMGSCv36mm8
Celera11132,329,807 - 132,333,656 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1184.31NCBI
ALYREF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381781,887,835 - 81,891,587 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1781,887,835 - 81,891,586 (-)EnsemblGRCh38hg38GRCh38
GRCh371779,845,711 - 79,849,463 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361777,439,016 - 77,442,758 (-)NCBINCBI36Build 36hg18NCBI36
Build 341777,439,016 - 77,442,758NCBI
Celera1776,449,564 - 76,453,306 (-)NCBICelera
Cytogenetic Map17q25.3NCBI
HuRef1775,247,636 - 75,251,146 (-)NCBIHuRef
CHM1_11779,931,915 - 79,935,666 (-)NCBICHM1_1
T2T-CHM13v2.01782,754,997 - 82,758,749 (-)NCBIT2T-CHM13v2.0
Alyref
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810106,369,750 - 106,373,395 (-)NCBIGRCr8
mRatBN7.210105,871,424 - 105,875,076 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10105,871,306 - 105,875,069 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10110,975,253 - 110,978,898 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010110,438,281 - 110,441,926 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010105,791,877 - 105,795,522 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010109,768,593 - 109,774,639 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10109,770,876 - 109,774,639 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010109,363,929 - 109,367,692 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410109,984,500 - 109,988,263 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera10104,414,714 - 104,418,477 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
Alyref
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555061,278,471 - 1,281,772 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555061,278,230 - 1,282,064 (+)NCBIChiLan1.0ChiLan1.0
ALYREF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21998,423,928 - 98,427,689 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan117103,324,715 - 103,328,469 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01776,293,410 - 76,297,171 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11781,995,578 - 82,000,836 (-)NCBIpanpan1.1PanPan1.1panPan2
ALYREF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.19398,207 - 402,787 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl9399,072 - 402,721 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha91,001,232 - 1,004,942 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.09992,434 - 996,142 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl9992,429 - 996,076 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.191,017,597 - 1,021,306 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.091,144,188 - 1,147,898 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.091,222,843 - 1,226,552 (+)NCBIUU_Cfam_GSD_1.0
Alyref
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056021,009,113 - 1,017,137 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365945,398,973 - 5,402,846 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALYREF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl121,092,329 - 1,103,054 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1121,099,239 - 1,103,058 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ALYREF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11673,761,763 - 73,765,560 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1673,757,072 - 73,765,531 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607745,213,965 - 45,217,836 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Alyref
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480110,733,907 - 10,738,124 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480110,734,392 - 10,738,191 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Alyref
149 total Variants

Predicted Target Of
Summary Value
Count of predictions:1296
Count of miRNA genes:622
Interacting mature miRNAs:791
Transcripts:ENSMUST00000026125, ENSMUST00000155325, ENSMUST00000156685
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 19 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
11251723Ewc5_methanol withdrawal and consumption 5 (mouse)1189869251121973369Mouse
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191604608121973369Mouse
1300944Alcp20_malcohol preference locus 20 (mouse)Not determined1195403965121973369Mouse
15014785Mvlq1_mmacrovesicular liver lesion QTL 1 (mouse)1186608320120608320Mouse
1301012Vispl_mvisual placing (mouse)Not determined11101022590121973369Mouse
15039374Adip29_madiposity 29 (mouse)1186608320120608320Mouse
1301983Berr2_mberghei resistance locus 2 (mouse)Not determined1198352609121973369Mouse
1300962Cd8mts4_mCD8 memory T cell subset 4 (mouse)Not determined1196137674121973369Mouse
10043976Obq33_mobesity QTL 33 (mouse)Not determined1198500469121973369Mouse
1301057Nidd4_mnon-insulin-dependent diabetes mellitus 4 (mouse)Not determined1196810136121973369Mouse

1 to 10 of 19 rows
Refbp2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381171,503,667 - 171,504,310UniSTSGRCm38
MGSCv371173,433,798 - 173,434,441UniSTSGRCm37
Celera1173,946,173 - 173,946,816UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map1H3UniSTS
cM Map1 UniSTS
cM Map179.48UniSTS
Thoc4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381171,503,900 - 171,504,298UniSTSGRCm38
MGSCv371173,434,031 - 173,434,429UniSTSGRCm37
Celera1173,946,406 - 173,946,804UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map1H3UniSTS
cM Map11 UniSTS
cM Map1184.31UniSTS
UniSTS:236797  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811120,592,193 - 120,592,443UniSTSGRCm38
MGSCv3711120,453,507 - 120,453,757UniSTSGRCm37
Celera11132,327,484 - 132,327,734UniSTS
Cytogenetic Map11E2UniSTS







Ensembl Acc Id: ENSMUST00000026125   ⟹   ENSMUSP00000026125
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11120,482,947 - 120,489,191 (-)Ensembl
GRCm38.p6 Ensembl11120,592,121 - 120,598,365 (-)Ensembl
Ensembl Acc Id: ENSMUST00000155325
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11120,485,335 - 120,486,483 (-)Ensembl
GRCm38.p6 Ensembl11120,594,509 - 120,595,657 (-)Ensembl
Ensembl Acc Id: ENSMUST00000156685
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11120,486,442 - 120,489,057 (-)Ensembl
GRCm38.p6 Ensembl11120,595,616 - 120,598,231 (-)Ensembl
RefSeq Acc Id: NM_011568   ⟹   NP_035698
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911120,485,342 - 120,489,191 (-)NCBI
GRCm3811120,594,516 - 120,598,365 (-)NCBI
MGSCv3711120,455,830 - 120,459,679 (-)RGD
Celera11132,329,807 - 132,333,656 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XR_001779950
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911120,485,330 - 120,489,342 (-)NCBI
GRCm3811120,594,504 - 120,598,399 (-)NCBI
Sequence:
1 to 10 of 10 rows
Protein RefSeqs NP_035698 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC53117 (Get FASTA)   NCBI Sequence Viewer  
  AAI20589 (Get FASTA)   NCBI Sequence Viewer  
  AAI37659 (Get FASTA)   NCBI Sequence Viewer  
  BAC29168 (Get FASTA)   NCBI Sequence Viewer  
  CAB76383 (Get FASTA)   NCBI Sequence Viewer  
  EDL34770 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000026125
  ENSMUSP00000026125.3
GenBank Protein O08583 (Get FASTA)   NCBI Sequence Viewer  
1 to 10 of 10 rows
RefSeq Acc Id: NP_035698   ⟸   NM_011568
- UniProtKB: Q8CBM4 (UniProtKB/Swiss-Prot),   Q0VBL5 (UniProtKB/Swiss-Prot),   Q9JJW7 (UniProtKB/Swiss-Prot),   O08583 (UniProtKB/Swiss-Prot),   Q4KL64 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000026125   ⟸   ENSMUST00000026125
RRM

Name Modeler Protein Id AA Range Protein Structure
AF-O08583-F1-model_v2 AlphaFold O08583 1-255 view protein structure

RGD ID:6820395
Promoter ID:MM_KWN:10938
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_001038230,   NM_025389,   OTTMUST00000009196,   OTTMUST00000009198,   OTTMUST00000061821
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3611120,458,941 - 120,460,062 (+)MPROMDB
RGD ID:8677698
Promoter ID:EPDNEW_M16880
Type:initiation region
Name:Alyref_1
Description:Mus musculus Aly/REF export factor , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3811120,598,353 - 120,598,413EPDNEW


1 to 30 of 30 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000025134 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000026125 ENTREZGENE
  ENSMUST00000026125.3 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot
InterPro ALYREF_mRNA_export UniProtKB/Swiss-Prot
  FoP_C UniProtKB/Swiss-Prot
  Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot
  RBD_domain_sf UniProtKB/Swiss-Prot
  RRM_dom UniProtKB/Swiss-Prot
KEGG Report mmu:21681 UniProtKB/Swiss-Prot
MGD MGI:1341044 ENTREZGENE
NCBI Gene 21681 ENTREZGENE
PANTHER RNA AND EXPORT FACTOR BINDING PROTEIN UniProtKB/Swiss-Prot
  THO COMPLEX SUBUNIT 4 UniProtKB/Swiss-Prot
Pfam FoP_duplication UniProtKB/Swiss-Prot
  RRM_1 UniProtKB/Swiss-Prot
PhenoGen Alyref PhenoGen
PROSITE RRM UniProtKB/Swiss-Prot
SMART FoP_duplication UniProtKB/Swiss-Prot
  RRM UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot
UniProt O08583 ENTREZGENE
  Q0VBL5 ENTREZGENE
  Q4KL64 ENTREZGENE
  Q8CBM4 ENTREZGENE
  Q9JJW7 ENTREZGENE
  THOC4_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q0VBL5 UniProtKB/Swiss-Prot
  Q8CBM4 UniProtKB/Swiss-Prot
  Q9JJW7 UniProtKB/Swiss-Prot
1 to 30 of 30 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-12-20 Alyref  Aly/REF export factor  Thoc4  THO complex 4  Symbol and/or name change 5135510 APPROVED