Hoxb1 (homeobox B1) - Rat Genome Database

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Gene: Hoxb1 (homeobox B1) Mus musculus
Analyze
Symbol: Hoxb1
Name: homeobox B1
RGD ID: 1321120
MGI Page MGI
Description: Enables sequence-specific DNA binding activity. Contributes to RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including central nervous system development; embryonic skeletal system morphogenesis; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; central nervous system; embryo ectoderm; embryo mesenchyme; and gut. Orthologous to human HOXB1 (homeobox B1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: homeo box B1; homeobox protein Hox-2.9; homeobox protein Hox-B1; Hox-2.; Hox-2.9; MGC124123
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391196,256,547 - 96,259,082 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1196,256,578 - 96,259,082 (+)EnsemblGRCm39 Ensembl
GRCm381196,365,746 - 96,368,254 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1196,365,752 - 96,368,256 (+)EnsemblGRCm38mm10GRCm38
MGSCv371196,227,072 - 96,229,567 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361196,181,848 - 96,183,766 (+)NCBIMGSCv36mm8
Celera11106,016,588 - 106,019,083 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1159.86NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
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Original Reference(s)
Hoxb1MouseVentricular Outflow Obstruction  IMP 11052805 RGD 
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Original Reference(s)
Hoxb1Mousegenetic disease  ISOHOXB1 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVar 
Hoxb1Mousehereditary breast ovarian cancer syndrome  ISOHOXB1 (Homo sapiens)8554872ClinVar Annotator: match by term: Breast-ovarian cancer more ...ClinVarPMID:38922859
Hoxb1MouseHereditary Congenital Facial Paresis 3  ISOHOXB1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:22770981 more ...
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Original Reference(s)
Hoxb1MouseCraniofacial Abnormalities  ISOHOXB1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:10529420
Hoxb1MouseHereditary Congenital Facial Paresis  ISOHOXB1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:24239177
Hoxb1MouseNervous System Malformations  ISOHOXB1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:10529420
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Original Reference(s)
Hoxb1MouseHereditary Congenital Facial Paresis 3  ISOHOXB1 (Homo sapiens)7240710 OMIM 

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Original Reference(s)
Hoxb1Mouse(+)-pilocarpine decreases expressionISOHoxb1 (Rattus norvegicus)6480464Pilocarpine results in decreased expression of HOXB1 mRNACTDPMID:17971868
Hoxb1Mouse2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of HOXB1 mRNACTDPMID:24058054
Hoxb1Mouse3',5'-cyclic AMP multiple interactionsISOHOXB1 (Homo sapiens)6480464[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of HOXB1 mRNACTDPMID:33713149
Hoxb1Mouse4,4'-sulfonyldiphenol affects methylationEXP 6480464bisphenol S affects the methylation of HOXB1 geneCTDPMID:31683443
Hoxb1Mouseacetaldehyde affects expressionEXP 6480464Acetaldehyde affects the expression of HOXB1 mRNACTDPMID:22634333
Hoxb1Mouseall-trans-retinoic acid increases expressionEXP 6480464Tretinoin results in increased expression of HOXB1 mRNACTDPMID:16038797 more ...
Hoxb1Mouseall-trans-retinoic acid multiple interactionsEXP 6480464[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HOXB1 mRNACTDPMID:36189433
Hoxb1Mouseall-trans-retinoic acid affects expressionISOHOXB1 (Homo sapiens)6480464Tretinoin affects the expression of HOXB1 mRNACTDPMID:31600526
Hoxb1Mouseall-trans-retinoic acid affects localizationEXP 6480464Tretinoin affects the localization of HOXB1 proteinCTDPMID:9184346
Hoxb1Mouseall-trans-retinoic acid increases expressionISOHOXB1 (Homo sapiens)6480464Tretinoin results in increased expression of HOXB1 mRNACTDPMID:21934132 and PMID:34742744
Hoxb1Mouseammonium chloride affects expressionISOHoxb1 (Rattus norvegicus)6480464Ammonium Chloride affects the expression of HOXB1 mRNACTDPMID:16483693
Hoxb1Mouseamosite asbestos decreases methylationISOHOXB1 (Homo sapiens)6480464Asbestos and Amosite results in decreased methylation of HOXB1 promoterCTDPMID:29626692
Hoxb1Mousearistolochic acid A increases expressionISOHOXB1 (Homo sapiens)6480464aristolochic acid I results in increased expression of HOXB1 mRNACTDPMID:33212167
Hoxb1Mousebenzo[a]pyrene decreases methylationEXP 6480464Benzo(a)pyrene results in decreased methylation of HOXB1 promoterCTDPMID:28476633
Hoxb1Mousebenzo[a]pyrene affects methylationISOHOXB1 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of HOXB1 promoterCTDPMID:27901495
Hoxb1Mousebis(2-ethylhexyl) phthalate decreases expressionISOHOXB1 (Homo sapiens)6480464Diethylhexyl Phthalate results in decreased expression of HOXB1 mRNACTDPMID:31163220
Hoxb1Mousebisphenol A decreases expressionISOHoxb1 (Rattus norvegicus)6480464bisphenol A results in decreased expression of HOXB1 mRNACTDPMID:25181051
Hoxb1Mousebisphenol A affects methylationEXP 6480464bisphenol A affects the methylation of HOXB1 promoterCTDPMID:27334623
Hoxb1Mousecarbamazepine affects expressionEXP 6480464Carbamazepine affects the expression of HOXB1 mRNACTDPMID:22634333
Hoxb1MouseCGP 52608 multiple interactionsISOHOXB1 (Homo sapiens)6480464CGP 52608 promotes the reaction [RORA protein binds to HOXB1 gene]CTDPMID:28238834

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Biological Process
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Original Reference(s)
Hoxb1Mouseanatomical structure formation involved in morphogenesis acts_upstream_of_or_withinIGIMGI:961702290270 PMID:10529420MGIPMID:10529420
Hoxb1Mouseanatomical structure morphogenesis acts_upstream_of_or_withinIGIMGI:961702290270 PMID:10529420MGIPMID:10529420
Hoxb1Mouseanterior/posterior pattern specification acts_upstream_of_or_withinIGIMGI:96183 more ...2290270 PMID:10885747MGIPMID:10885747
Hoxb1Mouseanterior/posterior pattern specification acts_upstream_of_or_withinIGIMGI:961702290270 PMID:10529420MGIPMID:10529420
Hoxb1Mouseembryonic skeletal system morphogenesis acts_upstream_of_or_withinIGIMGI:96183 more ...2290270 PMID:10885747MGIPMID:10885747
Hoxb1Mousefacial nerve structural organization acts_upstream_of_or_withinIMPMGI:18578242290270 PMID:8898234MGIPMID:8898234
Hoxb1Mousefacial nucleus development acts_upstream_of_or_withinIMPMGI:18578242290270 PMID:8898234MGIPMID:8898234
Hoxb1Mousepositive regulation of transcription by RNA polymerase II involved_inISOUniProtKB:P146532290270 GO_CentralGO_REF:0000119
Hoxb1Mousepositive regulation of transcription by RNA polymerase II acts_upstream_of_or_withinIDA 2290270 PMID:18787068MGIPMID:18787068
Hoxb1Mouseregulation of transcription by RNA polymerase II involved_inIBAPANTHER:PTN000675451 more ...2290270 GO_CentralGO_REF:0000033
Hoxb1Mouserhombomere 4 development acts_upstream_of_or_withinIGIMGI:961702290270 PMID:10529420MGIPMID:10529420
Hoxb1Mouserhombomere 5 development acts_upstream_of_or_withinIGIMGI:961702290270 PMID:10529420MGIPMID:10529420
Hoxb1Mouserhombomere development acts_upstream_of_or_withinIDA 2290270 PMID:21320481MGIPMID:21320481
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Cellular Component

  
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Original Reference(s)
Hoxb1Mousenucleoplasm located_inISOUniProtKB:P146532290270 GO_CentralGO_REF:0000119
Hoxb1Mousenucleoplasm located_inTAS 2290270 ReactomeReactome:R-MMU-5617982 more ...
Hoxb1Mousenucleus is_active_inIBAPANTHER:PTN000675451 more ...2290270 GO_CentralGO_REF:0000033

Molecular Function
1 to 14 of 14 rows

  
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Original Reference(s)
Hoxb1MouseDNA binding enablesISOUniProtKB:P146532290270 GO_CentralGO_REF:0000119
Hoxb1MouseDNA binding enablesIDA 2290270 PMID:7911971MGIPMID:7911971
Hoxb1MouseDNA-binding transcription activator activity, RNA polymerase II-specific enablesIEAUniProtKB:P14653 and ensembl:ENSP000003551402290270 EnsemblGO_REF:0000107
Hoxb1MouseDNA-binding transcription activator activity, RNA polymerase II-specific enablesISOUniProtKB:P146532290270 GO_CentralGO_REF:0000119
Hoxb1MouseDNA-binding transcription factor activity, RNA polymerase II-specific enablesIBAPANTHER:PTN000675451 more ...2290270 GO_CentralGO_REF:0000033
Hoxb1Mouseprotein binding enablesISOUniProtKB:Q9Y2P09068941 PMID:32296183IntActPMID:32296183
Hoxb1Mouseprotein binding enablesISOUniProtKB:P02489 more ...9068941 PMID:32814053IntActPMID:32814053
Hoxb1Mouseprotein domain specific binding enablesIEAUniProtKB:P14653 and ensembl:ENSP000003551402290270 EnsemblGO_REF:0000107
Hoxb1Mouseprotein domain specific binding enablesISOUniProtKB:P146532290270 GO_CentralGO_REF:0000119
Hoxb1MouseRNA polymerase II cis-regulatory region sequence-specific DNA binding enablesISOUniProtKB:P146532290270 GO_CentralGO_REF:0000119
Hoxb1MouseRNA polymerase II cis-regulatory region sequence-specific DNA binding contributes_toIDA 2290270 PMID:9242495MGIPMID:9242495
Hoxb1MouseRNA polymerase II transcription regulatory region sequence-specific DNA binding enablesISOUniProtKB:P146532290270 GO_CentralGO_REF:0000119
Hoxb1Mousesequence-specific DNA binding enablesIGIMGI:974952290270 PMID:18787068MGIPMID:18787068
Hoxb1Mousesequence-specific double-stranded DNA binding enablesISOUniProtKB:P146532290270 GO_CentralGO_REF:0000119
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1 to 20 of 97 rows
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Original Reference(s)
Hoxb1Mouseabnormal axon guidance  IAGP 5509061 MGIPMID:8967950
Hoxb1Mouseabnormal behavior  IAGP 5509061 MGIPMID:18155191
Hoxb1Mouseabnormal blinking  IAGP 5509061 MGIPMID:15198977
Hoxb1Mouseabnormal blinking  IAGP 5509061 MGIPMID:16890163
Hoxb1Mouseabnormal brainstem morphology  IAGP 5509061 MGIPMID:23408898
Hoxb1Mouseabnormal buccinator muscle morphology  IAGP 5509061 MGIPMID:8898234
Hoxb1Mouseabnormal cochlear outer hair cell morphology  IAGP 5509061 MGIPMID:23408898
Hoxb1Mouseabnormal cochlear VIII nucleus morphology  IAGP 5509061 MGIPMID:23408898
Hoxb1Mouseabnormal craniofacial morphology  IAGP 5509061 MGIPMID:15861402
Hoxb1Mouseabnormal craniofacial morphology  IAGP 5509061 MGIPMID:10529420
Hoxb1Mouseabnormal depressor anguli oris muscle morphology  IAGP 5509061 MGIPMID:8898234
Hoxb1Mouseabnormal digastric posterior belly morphology  IAGP 5509061 MGIPMID:8898234
Hoxb1Mouseabnormal digastric posterior belly morphology  IAGP 5509061 MGIPMID:10529420
Hoxb1Mouseabnormal facial motor nucleus morphology  IEA 5509061 MGI 
Hoxb1Mouseabnormal facial nerve morphology  IAGP 5509061 MGIPMID:8967950
Hoxb1Mouseabnormal facial nerve morphology  IAGP 5509061 MGIPMID:16890163
Hoxb1Mouseabnormal facial nerve morphology  IAGP 5509061 MGIPMID:15198977
Hoxb1Mouseabnormal facial nerve morphology  IAGP 5509061 MGIPMID:8898234
Hoxb1Mouseabnormal limb posture  IAGP 5509061 MGIPMID:18155191
Hoxb1Mouseabnormal locomotor coordination  IAGP 5509061 MGIPMID:18155191
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#
Reference Title
Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. MGD IEA MGD IEA
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Hoxb1 regulates proliferation and differentiation of second heart field progenitors in pharyngeal mesoderm and genetically interacts with Hoxa1 during cardiac outflow tract development. Roux M, etal., Dev Biol. 2015 Oct 15;406(2):247-58. doi: 10.1016/j.ydbio.2015.08.015. Epub 2015 Aug 15.
1 to 10 of 27 rows
PMID:1348361   PMID:1356009   PMID:1358459   PMID:1363087   PMID:1673098   PMID:1682814   PMID:1685117   PMID:1688181   PMID:1972280   PMID:1983472   PMID:2571087   PMID:2571936  
PMID:4075393   PMID:7477375   PMID:7477376   PMID:7588062   PMID:7607086   PMID:7635047   PMID:7669695   PMID:7671812   PMID:7903221   PMID:7903600   PMID:7903601   PMID:7903632  
PMID:7903957   PMID:7911971   PMID:7914354   PMID:7915637   PMID:7916164   PMID:7918100   PMID:7925021   PMID:7925028   PMID:7947319   PMID:7956823   PMID:8001130   PMID:8069909  
PMID:8096385   PMID:8100767   PMID:8102800   PMID:8105001   PMID:8105479   PMID:8224839   PMID:8555112   PMID:8563168   PMID:8565836   PMID:8703472   PMID:8756292   PMID:8798145  
PMID:8801179   PMID:8898234   PMID:8967950   PMID:8986815   PMID:9012503   PMID:9053316   PMID:9102308   PMID:9226455   PMID:9242495   PMID:9247335   PMID:9256343   PMID:9262482  
PMID:9271116   PMID:9291463   PMID:9334279   PMID:9337135   PMID:9367423   PMID:9367425   PMID:9415428   PMID:9449667   PMID:9463349   PMID:9463359   PMID:9598353   PMID:9671576  
PMID:9671595   PMID:9712518   PMID:9716520   PMID:9732271   PMID:9767163   PMID:9790191   PMID:9806826   PMID:9806922   PMID:9811592   PMID:10349636   PMID:10354604   PMID:10357893  
PMID:10381567   PMID:10395784   PMID:10421635   PMID:10431240   PMID:10440864   PMID:10529420   PMID:10529422   PMID:10529425   PMID:10556076   PMID:10642791   PMID:10654602   PMID:10662633  
PMID:10885747   PMID:10922068   PMID:11042159   PMID:11044609   PMID:11044623   PMID:11076752   PMID:11076756   PMID:11076861   PMID:11118901   PMID:11157778   PMID:11163240   PMID:11217851  
PMID:11278854   PMID:11291866   PMID:11356033   PMID:11412024   PMID:11466434   PMID:11493525   PMID:11511348   PMID:11528388   PMID:11532923   PMID:11566859   PMID:11731459   PMID:11748134  
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Hoxb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391196,256,547 - 96,259,082 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1196,256,578 - 96,259,082 (+)EnsemblGRCm39 Ensembl
GRCm381196,365,746 - 96,368,254 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1196,365,752 - 96,368,256 (+)EnsemblGRCm38mm10GRCm38
MGSCv371196,227,072 - 96,229,567 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361196,181,848 - 96,183,766 (+)NCBIMGSCv36mm8
Celera11106,016,588 - 106,019,083 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1159.86NCBI
HOXB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381748,528,526 - 48,531,011 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1748,528,526 - 48,531,011 (-)EnsemblGRCh38hg38GRCh38
GRCh371746,605,888 - 46,608,373 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361743,961,806 - 43,963,271 (-)NCBINCBI36Build 36hg18NCBI36
Build 341743,961,812 - 43,963,271NCBI
Celera1743,060,953 - 43,062,427 (-)NCBICelera
Cytogenetic Map17q21.32NCBI
HuRef1741,976,125 - 41,977,599 (-)NCBIHuRef
CHM1_11746,672,595 - 46,674,060 (-)NCBICHM1_1
T2T-CHM13v2.01749,391,954 - 49,394,439 (-)NCBIT2T-CHM13v2.0
Hoxb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81081,827,915 - 81,830,404 (+)NCBIGRCr8
mRatBN7.21081,331,507 - 81,332,928 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1081,331,507 - 81,332,836 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01084,214,358 - 84,215,812 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1084,214,358 - 84,215,687 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01084,017,011 - 84,018,433 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41085,098,903 - 85,100,308 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11085,102,648 - 85,114,602 (+)NCBI
Celera1080,097,554 - 80,099,008 (+)NCBICelera
Cytogenetic Map10q26NCBI
Hoxb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545112,707,462 - 12,709,899 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545112,707,560 - 12,708,950 (+)NCBIChiLan1.0ChiLan1.0
HOXB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21916,571,773 - 16,573,681 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11718,537,363 - 18,539,898 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0179,005,745 - 9,008,230 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1179,190,137 - 9,191,696 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl179,190,137 - 9,191,696 (+)Ensemblpanpan1.1panPan2
HOXB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1924,791,848 - 24,795,443 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl924,792,889 - 24,794,302 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha924,256,127 - 24,259,664 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0925,586,553 - 25,590,090 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl925,587,585 - 25,588,998 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1924,354,782 - 24,358,319 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0924,615,222 - 24,618,759 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0924,743,539 - 24,747,076 (-)NCBIUU_Cfam_GSD_1.0
Hoxb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560224,218,714 - 24,222,497 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649012,853,983 - 12,855,428 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649012,853,983 - 12,855,428 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HOXB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1224,784,594 - 24,786,576 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11224,784,953 - 24,786,377 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21224,742,328 - 24,743,755 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HOXB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11668,940,726 - 68,945,153 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1668,941,746 - 68,943,111 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607739,995,445 - 39,997,937 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hoxb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247955,032,495 - 5,033,789 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247955,032,495 - 5,033,789 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Hoxb1
61 total Variants

Predicted Target Of
Summary Value
Count of predictions:617
Count of miRNA genes:397
Interacting mature miRNAs:454
Transcripts:ENSMUST00000019117, ENSMUST00000123805
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 60 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191604608121973369Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1301535Pas5b_mpulmonary adenoma susceptibility 5b (mouse)Not determined1196176465108806384Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181574481115574636Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
27226758Femd3_mfemur midshaft diameter 3, 5 week (mouse)1180890826101890826Mouse

1 to 10 of 60 rows
Hoxb1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381196,365,765 - 96,366,265UniSTSGRCm38
MGSCv371196,227,079 - 96,227,579UniSTSGRCm37
Celera11106,016,595 - 106,017,095UniSTS
Cytogenetic Map11DUniSTS
cM Map1156.2UniSTS
UniSTS:236712  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381196,368,024 - 96,368,232UniSTSGRCm38
MGSCv371196,229,338 - 96,229,546UniSTSGRCm37
Celera11106,018,854 - 106,019,062UniSTS
Cytogenetic Map11DUniSTS
cM Map1156.08UniSTS
UniSTS:236714  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381196,367,515 - 96,367,602UniSTSGRCm38
MGSCv371196,228,829 - 96,228,916UniSTSGRCm37
Celera11106,018,345 - 106,018,432UniSTS
Cytogenetic Map11DUniSTS
cM Map1156.08UniSTS
PMC117285P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381196,366,111 - 96,367,015UniSTSGRCm38
MGSCv371196,227,425 - 96,228,329UniSTSGRCm37
Celera11106,016,941 - 106,017,845UniSTS
Cytogenetic Map11DUniSTS
cM Map1156.08UniSTS
Hoxb1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11DUniSTS
Hoxb1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381196,367,174 - 96,367,477UniSTSGRCm38
MGSCv371196,228,488 - 96,228,791UniSTSGRCm37
Celera11106,018,004 - 106,018,307UniSTS
Cytogenetic Map11DUniSTS
Hoxb1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381196,366,345 - 96,367,089UniSTSGRCm38
MGSCv371196,227,659 - 96,228,403UniSTSGRCm37
Celera11106,017,175 - 106,017,919UniSTS
Cytogenetic Map11DUniSTS
cM Map1156.2UniSTS
Hoxb1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381196,366,357 - 96,367,674UniSTSGRCm38
MGSCv371196,227,671 - 96,228,988UniSTSGRCm37
Celera11106,017,187 - 106,018,504UniSTS
Cytogenetic Map11DUniSTS
cM Map1156.2UniSTS
Hoxb1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11DUniSTS







Ensembl Acc Id: ENSMUST00000019117   ⟹   ENSMUSP00000019117
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1196,256,578 - 96,259,082 (+)Ensembl
GRCm38.p6 Ensembl1196,365,752 - 96,368,256 (+)Ensembl
Ensembl Acc Id: ENSMUST00000123805
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1196,257,084 - 96,258,047 (+)Ensembl
GRCm38.p6 Ensembl1196,366,258 - 96,367,221 (+)Ensembl
RefSeq Acc Id: NM_008266   ⟹   NP_032292
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391196,256,547 - 96,259,082 (+)NCBI
GRCm381196,365,758 - 96,368,253 (+)NCBI
MGSCv371196,227,072 - 96,229,567 (+)RGD
Celera11106,016,588 - 106,019,083 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006532280   ⟹   XP_006532343
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391196,256,572 - 96,259,080 (+)NCBI
GRCm381196,365,746 - 96,368,254 (+)NCBI
Sequence:
RefSeq Acc Id: NP_032292   ⟸   NM_008266
- UniProtKB: Q3ZAY6 (UniProtKB/Swiss-Prot),   Q9CYH3 (UniProtKB/Swiss-Prot),   P17919 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006532343   ⟸   XM_006532280
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSMUSP00000019117   ⟸   ENSMUST00000019117

Name Modeler Protein Id AA Range Protein Structure
AF-P17919-F1-model_v2 AlphaFold P17919 1-297 view protein structure

RGD ID:8676346
Promoter ID:EPDNEW_M16204
Type:initiation region
Name:Hoxb1_1
Description:Mus musculus homeobox B1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381196,365,722 - 96,365,782EPDNEW


1 to 27 of 27 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000018973 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000019117 ENTREZGENE
  ENSMUST00000019117.3 UniProtKB/Swiss-Prot
Gene3D-CATH Homeodomain-like UniProtKB/Swiss-Prot
InterPro Homeobox-like_sf UniProtKB/Swiss-Prot
  Homeobox_CS UniProtKB/Swiss-Prot
  Homeobox_dom UniProtKB/Swiss-Prot
  Homeobox_metazoa UniProtKB/Swiss-Prot
  HXA1/B1/D1 UniProtKB/Swiss-Prot
KEGG Report mmu:15407 UniProtKB/Swiss-Prot
MGD MGI:96182 ENTREZGENE
NCBI Gene 15407 ENTREZGENE
PANTHER HOMEOBOX PROTEIN HOX-B1 UniProtKB/Swiss-Prot
  PTHR45946 UniProtKB/Swiss-Prot
Pfam Homeodomain UniProtKB/Swiss-Prot
PhenoGen Hoxb1 PhenoGen
PRINTS HOMEOBOX UniProtKB/Swiss-Prot
PROSITE HOMEOBOX_1 UniProtKB/Swiss-Prot
  HOMEOBOX_2 UniProtKB/Swiss-Prot
SMART HOX UniProtKB/Swiss-Prot
Superfamily-SCOP SSF46689 UniProtKB/Swiss-Prot
UniProt HXB1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3ZAX9_MOUSE UniProtKB/TrEMBL
  Q3ZAY6 ENTREZGENE
  Q9CYH3 ENTREZGENE
UniProt Secondary Q3ZAY6 UniProtKB/Swiss-Prot
  Q9CYH3 UniProtKB/Swiss-Prot
1 to 27 of 27 rows