Hoxb1 (homeobox B1) - Rat Genome Database

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Gene: Hoxb1 (homeobox B1) Mus musculus
Analyze
Symbol: Hoxb1
Name: homeobox B1
RGD ID: 1321120
MGI Page MGI
Description: Enables sequence-specific DNA binding activity. Contributes to RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including central nervous system development; embryonic skeletal system morphogenesis; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; central nervous system; embryo ectoderm; embryo mesenchyme; and gut. Orthologous to human HOXB1 (homeobox B1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: homeo box B1; homeobox protein Hox-2.9; homeobox protein Hox-B1; Hox-2.; Hox-2.9; MGC124123
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391196,256,547 - 96,259,082 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1196,256,578 - 96,259,082 (+)EnsemblGRCm39 Ensembl
GRCm381196,365,746 - 96,368,254 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1196,365,752 - 96,368,256 (+)EnsemblGRCm38mm10GRCm38
MGSCv371196,227,072 - 96,229,567 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361196,181,848 - 96,183,766 (+)NCBIMGSCv36mm8
Celera11106,016,588 - 106,019,083 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1159.86NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (ISO,TAS)
nucleus  (IBA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal axon guidance  (IAGP)
abnormal behavior  (IAGP)
abnormal blinking  (IAGP)
abnormal brainstem morphology  (IAGP)
abnormal buccinator muscle morphology  (IAGP)
abnormal cochlear outer hair cell morphology  (IAGP)
abnormal cochlear VIII nucleus morphology  (IAGP)
abnormal craniofacial morphology  (IAGP)
abnormal depressor anguli oris muscle morphology  (IAGP)
abnormal digastric posterior belly morphology  (IAGP)
abnormal facial motor nucleus morphology  (IEA)
abnormal facial nerve morphology  (IAGP)
abnormal limb posture  (IAGP)
abnormal locomotor coordination  (IAGP)
abnormal lower lip morphology  (IAGP)
abnormal masseter muscle morphology  (IAGP)
abnormal nervous system morphology  (IAGP)
abnormal neural crest cell delamination  (IAGP)
abnormal neural crest cell migration  (IAGP)
abnormal neuron differentiation  (IAGP)
abnormal neuron morphology  (IAGP)
abnormal organ of Corti morphology  (IAGP)
abnormal pharyngeal pouch morphology  (IAGP)
abnormal pons morphology  (IAGP)
abnormal reflex  (IAGP)
abnormal rhombomere 4 morphology  (IAGP)
abnormal rhombomere morphology  (IAGP)
abnormal spinal cord dorsal horn morphology  (IAGP)
abnormal stylohyoid muscle morphology  (IAGP)
abnormal susceptibility to hearing loss  (IAGP)
abnormal temporalis muscle morphology  (IAGP)
abnormal third pharyngeal pouch morphology  (IAGP)
abnormal tooth morphology  (IAGP)
abnormal vibrissae reflex  (IAGP)
abnormal zygomaticus muscle morphology  (IAGP)
absent facial muscle  (IAGP)
absent facial nerve  (IAGP)
absent facial nuclei  (IAGP)
absent levator labii superioris muscle  (IAGP)
absent levator nasolabialis muscle  (IAGP)
absent orbicularis oculi muscle  (IAGP)
absent parathyroid glands  (IAGP)
absent rhombomere 4  (IAGP)
absent rhombomere 5  (IAGP)
absent second pharyngeal arch  (IAGP)
absent second pharyngeal pouch  (IAGP)
absent stapes  (IAGP)
absent zygomaticus muscle  (IAGP)
athymia  (IAGP)
bradykinesia  (IAGP)
decreased body size  (IAGP)
decreased motor neuron number  (IAGP)
decreased neuron number  (IAGP)
decreased sensory neuron number  (IAGP)
decreased thermal nociceptive threshold  (IAGP)
facial muscle degeneration  (IAGP)
facial paralysis  (IAGP)
hyporesponsive to tactile stimuli  (IAGP)
impaired coordination  (IAGP)
improved righting response  (IAGP)
increased hindbrain apoptosis  (IAGP)
increased or absent threshold for auditory brainstem response  (IAGP)
increased startle reflex  (IAGP)
increased susceptibility to age-related hearing loss  (IAGP)
limb grasping  (IAGP)
narrow face  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
paralysis  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
pulmonary hypoplasia  (IAGP)
small facial motor nucleus  (IAGP)
small incus  (IAGP)
small malleus  (IAGP)
small thymus  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. MGD IEA MGD IEA
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Hoxb1 regulates proliferation and differentiation of second heart field progenitors in pharyngeal mesoderm and genetically interacts with Hoxa1 during cardiac outflow tract development. Roux M, etal., Dev Biol. 2015 Oct 15;406(2):247-58. doi: 10.1016/j.ydbio.2015.08.015. Epub 2015 Aug 15.
Additional References at PubMed
PMID:1348361   PMID:1356009   PMID:1358459   PMID:1363087   PMID:1673098   PMID:1682814   PMID:1685117   PMID:1688181   PMID:1972280   PMID:1983472   PMID:2571087   PMID:2571936  
PMID:4075393   PMID:7477375   PMID:7477376   PMID:7588062   PMID:7607086   PMID:7635047   PMID:7669695   PMID:7671812   PMID:7903221   PMID:7903600   PMID:7903601   PMID:7903632  
PMID:7903957   PMID:7911971   PMID:7914354   PMID:7915637   PMID:7916164   PMID:7918100   PMID:7925021   PMID:7925028   PMID:7947319   PMID:7956823   PMID:8001130   PMID:8069909  
PMID:8096385   PMID:8100767   PMID:8102800   PMID:8105001   PMID:8105479   PMID:8224839   PMID:8555112   PMID:8563168   PMID:8565836   PMID:8703472   PMID:8756292   PMID:8798145  
PMID:8801179   PMID:8898234   PMID:8967950   PMID:8986815   PMID:9012503   PMID:9053316   PMID:9102308   PMID:9226455   PMID:9242495   PMID:9247335   PMID:9256343   PMID:9262482  
PMID:9271116   PMID:9291463   PMID:9334279   PMID:9337135   PMID:9367423   PMID:9367425   PMID:9415428   PMID:9449667   PMID:9463349   PMID:9463359   PMID:9598353   PMID:9671576  
PMID:9671595   PMID:9712518   PMID:9716520   PMID:9732271   PMID:9767163   PMID:9790191   PMID:9806826   PMID:9806922   PMID:9811592   PMID:10349636   PMID:10354604   PMID:10357893  
PMID:10381567   PMID:10395784   PMID:10421635   PMID:10431240   PMID:10440864   PMID:10529420   PMID:10529422   PMID:10529425   PMID:10556076   PMID:10642791   PMID:10654602   PMID:10662633  
PMID:10885747   PMID:10922068   PMID:11042159   PMID:11044609   PMID:11044623   PMID:11076752   PMID:11076756   PMID:11076861   PMID:11118901   PMID:11157778   PMID:11163240   PMID:11217851  
PMID:11278854   PMID:11291866   PMID:11356033   PMID:11412024   PMID:11466434   PMID:11493525   PMID:11511348   PMID:11528388   PMID:11532923   PMID:11566859   PMID:11731459   PMID:11748134  
PMID:11748135   PMID:11782416   PMID:11880356   PMID:11891985   PMID:11953746   PMID:12015293   PMID:12070080   PMID:12086465   PMID:12204252   PMID:12385756   PMID:12431380   PMID:12466851  
PMID:12471260   PMID:12477932   PMID:12514106   PMID:12563036   PMID:12589020   PMID:12645927   PMID:12651891   PMID:12701106   PMID:12702665   PMID:12753872   PMID:12805229   PMID:12810586  
PMID:12815623   PMID:12835396   PMID:12915323   PMID:12954718   PMID:14522873   PMID:14534138   PMID:14604764   PMID:14745958   PMID:14960494   PMID:15034141   PMID:15042701   PMID:15136723  
PMID:15198977   PMID:15367676   PMID:15489334   PMID:15618518   PMID:15680353   PMID:15741321   PMID:15741322   PMID:15750184   PMID:15765518   PMID:15790971   PMID:15829521   PMID:15829525  
PMID:15857914   PMID:15861402   PMID:15872003   PMID:15944185   PMID:16141072   PMID:16141073   PMID:16166636   PMID:16221730   PMID:16274963   PMID:16399080   PMID:16452098   PMID:16481355  
PMID:16489219   PMID:16508307   PMID:16537918   PMID:16540515   PMID:16678814   PMID:16845371   PMID:16890163   PMID:16914493   PMID:16971476   PMID:17026983   PMID:17067568   PMID:17119020  
PMID:17126317   PMID:17241623   PMID:17507393   PMID:17601531   PMID:17652354   PMID:17676634   PMID:17728342   PMID:17900554   PMID:17922007   PMID:18061570   PMID:18155191   PMID:18164701  
PMID:18252796   PMID:18287559   PMID:18332127   PMID:18495817   PMID:18499896   PMID:18554416   PMID:18697938   PMID:18723448   PMID:18787068   PMID:18799693   PMID:19056886   PMID:19204410  
PMID:19235731   PMID:19527706   PMID:19541997   PMID:19741118   PMID:19933700   PMID:20059953   PMID:20162674   PMID:20171203   PMID:20211142   PMID:20230754   PMID:20235227   PMID:20631168  
PMID:20816794   PMID:20932939   PMID:21173260   PMID:21245162   PMID:21320481   PMID:21362415   PMID:21385575   PMID:21497760   PMID:21554866   PMID:21637844   PMID:21674689   PMID:21677750  
PMID:21731673   PMID:21753013   PMID:21784065   PMID:21873635   PMID:21930923   PMID:21945624   PMID:21982646   PMID:22110056   PMID:22363567   PMID:22485187   PMID:22675207   PMID:22701719  
PMID:22954964   PMID:23041177   PMID:23408898   PMID:23578930   PMID:23637629   PMID:23760955   PMID:23852112   PMID:24010020   PMID:24080509   PMID:24146773   PMID:24357327   PMID:24525295  
PMID:24633704   PMID:24803591   PMID:24952961   PMID:24998526   PMID:25031030   PMID:25079229   PMID:25190705   PMID:25263278   PMID:25309446   PMID:26283362   PMID:26447130   PMID:26534985  
PMID:26586220   PMID:26730404   PMID:26914477   PMID:27026076   PMID:27194336   PMID:27956219   PMID:28041967   PMID:28188179   PMID:28380068   PMID:30254164   PMID:30959515   PMID:30992047  
PMID:31341279   PMID:31666356   PMID:31928974   PMID:32047912   PMID:32439762   PMID:32479258   PMID:32562661   PMID:32804075   PMID:33171097   PMID:33230114   PMID:33257809   PMID:33452727  
PMID:33505317   PMID:34099102   PMID:34124068   PMID:34321664   PMID:35257173   PMID:35817961   PMID:35857513   PMID:36041259   PMID:36398878   PMID:37102683   PMID:37397253   PMID:37738262  


Genomics

Comparative Map Data
Hoxb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391196,256,547 - 96,259,082 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1196,256,578 - 96,259,082 (+)EnsemblGRCm39 Ensembl
GRCm381196,365,746 - 96,368,254 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1196,365,752 - 96,368,256 (+)EnsemblGRCm38mm10GRCm38
MGSCv371196,227,072 - 96,229,567 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361196,181,848 - 96,183,766 (+)NCBIMGSCv36mm8
Celera11106,016,588 - 106,019,083 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1159.86NCBI
HOXB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381748,528,526 - 48,531,011 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1748,528,526 - 48,531,011 (-)EnsemblGRCh38hg38GRCh38
GRCh371746,605,888 - 46,608,373 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361743,961,806 - 43,963,271 (-)NCBINCBI36Build 36hg18NCBI36
Build 341743,961,812 - 43,963,271NCBI
Celera1743,060,953 - 43,062,427 (-)NCBICelera
Cytogenetic Map17q21.32NCBI
HuRef1741,976,125 - 41,977,599 (-)NCBIHuRef
CHM1_11746,672,595 - 46,674,060 (-)NCBICHM1_1
T2T-CHM13v2.01749,391,954 - 49,394,439 (-)NCBIT2T-CHM13v2.0
Hoxb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81081,827,915 - 81,830,404 (+)NCBIGRCr8
mRatBN7.21081,331,507 - 81,332,928 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1081,331,507 - 81,332,836 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01084,214,358 - 84,215,812 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1084,214,358 - 84,215,687 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01084,017,011 - 84,018,433 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41085,098,903 - 85,100,308 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11085,102,648 - 85,114,602 (+)NCBI
Celera1080,097,554 - 80,099,008 (+)NCBICelera
Cytogenetic Map10q26NCBI
Hoxb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545112,707,462 - 12,709,899 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545112,707,560 - 12,708,950 (+)NCBIChiLan1.0ChiLan1.0
HOXB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21916,571,773 - 16,573,681 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11718,537,363 - 18,539,898 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0179,005,745 - 9,008,230 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1179,190,137 - 9,191,696 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl179,190,137 - 9,191,696 (+)Ensemblpanpan1.1panPan2
HOXB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1924,791,848 - 24,795,443 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl924,792,889 - 24,794,302 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha924,256,127 - 24,259,664 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0925,586,553 - 25,590,090 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl925,587,585 - 25,588,998 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1924,354,782 - 24,358,319 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0924,615,222 - 24,618,759 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0924,743,539 - 24,747,076 (-)NCBIUU_Cfam_GSD_1.0
Hoxb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560224,218,714 - 24,222,497 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649012,853,983 - 12,855,428 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649012,853,983 - 12,855,428 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HOXB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1224,784,594 - 24,786,576 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11224,784,953 - 24,786,377 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21224,742,328 - 24,743,755 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HOXB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11668,940,726 - 68,945,153 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1668,941,746 - 68,943,111 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607739,995,445 - 39,997,937 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hoxb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247955,032,495 - 5,033,789 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247955,032,495 - 5,033,789 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hoxb1
61 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:617
Count of miRNA genes:397
Interacting mature miRNAs:454
Transcripts:ENSMUST00000019117, ENSMUST00000123805
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191604608121973369Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1301535Pas5b_mpulmonary adenoma susceptibility 5b (mouse)Not determined1196176465108806384Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181574481115574636Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
27226758Femd3_mfemur midshaft diameter 3, 5 week (mouse)1180890826101890826Mouse
14747003Mancz9_mmandible centroid size 9 (mouse)1185844911119844911Mouse
1301640Lore4_mloss of righting induced by ethanol 4 (mouse)Not determined1179156009107616472Mouse
14700796Syncq9_msynovial calcification QTL 9 (mouse)119593782696992826Mouse
10412288Carg4_mCandida albicans resistance gene 4 (mouse)Not determined1181810267115810267Mouse
11251723Ewc5_methanol withdrawal and consumption 5 (mouse)1189869251121973369Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170691198104691366Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170691198104691366Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177770978111771099Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
4141465Dbm2_mdiabetes modifier 2 (mouse)Not determined94437183118022724Mouse
10045617Heal26_mwound healing/regeneration 26 (mouse)Not determined1192939373112544554Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177437183111437322Mouse
1357631Motr1_mmodifier of tubby retinal degeneration 1 (mouse)Not determined1187691198103274115Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172726125106726289Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172818615106818733Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177437183111437322Mouse
15092049Wsigrme3_mweek six growth rate, maternal effect 3 (mouse)118487732496629512Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170691198104691366Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1300649Crhq1_mcompensatory renal hypertrophy QTL 1 (mouse)Not determined1181574481115574636Mouse
27226789Feml16_mfemur length 16, 10 week (mouse)1187490826121873369Mouse
14746970Manh71_mmandible shape 71 (mouse)1179416257113416257Mouse
15092057Lgrme3_mlate growth rate, maternal effect 3 (mouse)118487732496629512Mouse
10043865T2dm5sa_mtype 2 diabetes mellitus 5 in SMXA RI mice (mouse)Not determined1179813759104502698Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172818615106818733Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182377698116377820Mouse
1300944Alcp20_malcohol preference locus 20 (mouse)Not determined1195403965121973369Mouse
4141939Pregq2_mpregnancy QTL 2 (mouse)Not determined1194063779118022724Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177063779111063918Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
1301958Alcp18_malcohol preference locus 18 (mouse)Not determined1195403965121973369Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
1301491Abbp4_mA/J and C57BL/6 blood pressure 4 (mouse)Not determined118869958899081597Mouse
15014785Mvlq1_mmacrovesicular liver lesion QTL 1 (mouse)1186608320120608320Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
15039374Adip29_madiposity 29 (mouse)1186608320120608320Mouse
1300962Cd8mts4_mCD8 memory T cell subset 4 (mouse)Not determined1196137674121973369Mouse
1301095El6_mepilepsy 6 (mouse)Not determined1193229183121973369Mouse
27226731Tibmd4_mtibia midshaft diameter 4, 10 week (mouse)1194190826118890826Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
15039376Bw42_mbody weight QTL 42 (mouse)1186608320120608320Mouse
1558753Ath19_matherosclerosis 19 (mouse)Not determined1191604608121973369Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
10044007Hbnr14_mHeligmosomoides bakeri nematode resistance 14 (mouse)Not determined1187502600121502698Mouse
1302124Eae7_msusceptibility to experimental allergic encephalomyelitis 7 (mouse)Not determined117757387399377820Mouse
13524529Bodwtq10_mbody wweight QTL 10 (mouse)119067951297699512Mouse

Markers in Region
Hoxb1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381196,365,765 - 96,366,265UniSTSGRCm38
MGSCv371196,227,079 - 96,227,579UniSTSGRCm37
Celera11106,016,595 - 106,017,095UniSTS
Cytogenetic Map11DUniSTS
cM Map1156.2UniSTS
UniSTS:236712  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381196,368,024 - 96,368,232UniSTSGRCm38
MGSCv371196,229,338 - 96,229,546UniSTSGRCm37
Celera11106,018,854 - 106,019,062UniSTS
Cytogenetic Map11DUniSTS
cM Map1156.08UniSTS
UniSTS:236714  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381196,367,515 - 96,367,602UniSTSGRCm38
MGSCv371196,228,829 - 96,228,916UniSTSGRCm37
Celera11106,018,345 - 106,018,432UniSTS
Cytogenetic Map11DUniSTS
cM Map1156.08UniSTS
PMC117285P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381196,366,111 - 96,367,015UniSTSGRCm38
MGSCv371196,227,425 - 96,228,329UniSTSGRCm37
Celera11106,016,941 - 106,017,845UniSTS
Cytogenetic Map11DUniSTS
cM Map1156.08UniSTS
Hoxb1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11DUniSTS
Hoxb1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381196,367,174 - 96,367,477UniSTSGRCm38
MGSCv371196,228,488 - 96,228,791UniSTSGRCm37
Celera11106,018,004 - 106,018,307UniSTS
Cytogenetic Map11DUniSTS
Hoxb1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381196,366,345 - 96,367,089UniSTSGRCm38
MGSCv371196,227,659 - 96,228,403UniSTSGRCm37
Celera11106,017,175 - 106,017,919UniSTS
Cytogenetic Map11DUniSTS
cM Map1156.2UniSTS
Hoxb1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381196,366,357 - 96,367,674UniSTSGRCm38
MGSCv371196,227,671 - 96,228,988UniSTSGRCm37
Celera11106,017,187 - 106,018,504UniSTS
Cytogenetic Map11DUniSTS
cM Map1156.2UniSTS
Hoxb1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11DUniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000019117   ⟹   ENSMUSP00000019117
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1196,256,578 - 96,259,082 (+)Ensembl
GRCm38.p6 Ensembl1196,365,752 - 96,368,256 (+)Ensembl
Ensembl Acc Id: ENSMUST00000123805
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1196,257,084 - 96,258,047 (+)Ensembl
GRCm38.p6 Ensembl1196,366,258 - 96,367,221 (+)Ensembl
RefSeq Acc Id: NM_008266   ⟹   NP_032292
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391196,256,547 - 96,259,082 (+)NCBI
GRCm381196,365,758 - 96,368,253 (+)NCBI
MGSCv371196,227,072 - 96,229,567 (+)RGD
Celera11106,016,588 - 106,019,083 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006532280   ⟹   XP_006532343
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391196,256,572 - 96,259,080 (+)NCBI
GRCm381196,365,746 - 96,368,254 (+)NCBI
Sequence:
RefSeq Acc Id: NP_032292   ⟸   NM_008266
- UniProtKB: Q3ZAY6 (UniProtKB/Swiss-Prot),   Q9CYH3 (UniProtKB/Swiss-Prot),   P17919 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006532343   ⟸   XM_006532280
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSMUSP00000019117   ⟸   ENSMUST00000019117

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P17919-F1-model_v2 AlphaFold P17919 1-297 view protein structure

Promoters
RGD ID:8676346
Promoter ID:EPDNEW_M16204
Type:initiation region
Name:Hoxb1_1
Description:Mus musculus homeobox B1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381196,365,722 - 96,365,782EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96182 AgrOrtholog
Ensembl Genes ENSMUSG00000018973 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000019117 ENTREZGENE
  ENSMUST00000019117.3 UniProtKB/Swiss-Prot
Gene3D-CATH Homeodomain-like UniProtKB/Swiss-Prot
InterPro Homeobox-like_sf UniProtKB/Swiss-Prot
  Homeobox_CS UniProtKB/Swiss-Prot
  Homeobox_dom UniProtKB/Swiss-Prot
  Homeobox_metazoa UniProtKB/Swiss-Prot
  HXA1/B1/D1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:15407 UniProtKB/Swiss-Prot
MGD MGI:96182 ENTREZGENE
NCBI Gene 15407 ENTREZGENE
PANTHER HOMEOBOX PROTEIN HOX-B1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR45946 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Homeodomain UniProtKB/Swiss-Prot
PhenoGen Hoxb1 PhenoGen
PRINTS HOMEOBOX UniProtKB/Swiss-Prot
PROSITE HOMEOBOX_1 UniProtKB/Swiss-Prot
  HOMEOBOX_2 UniProtKB/Swiss-Prot
SMART HOX UniProtKB/Swiss-Prot
Superfamily-SCOP SSF46689 UniProtKB/Swiss-Prot
UniProt HXB1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3ZAX9_MOUSE UniProtKB/TrEMBL
  Q3ZAY6 ENTREZGENE
  Q9CYH3 ENTREZGENE
UniProt Secondary Q3ZAY6 UniProtKB/Swiss-Prot
  Q9CYH3 UniProtKB/Swiss-Prot