Tmem220 (transmembrane protein 220) - Rat Genome Database
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Gene: Tmem220 (transmembrane protein 220) Mus musculus
Analyze
Symbol: Tmem220
Name: transmembrane protein 220
RGD ID: 1319987
MGI Page MGI
Description: Orthologous to human TMEM220 (transmembrane protein 220); INTERACTS WITH 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A730055C05Rik; MGC130169; MGC130170; RP23-67J22.6
RGD Orthologs
Human
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391166,915,959 - 66,927,818 (+)NCBIGRCm39mm39
GRCm39 Ensembl1166,915,980 - 66,926,138 (+)Ensembl
GRCm381167,025,154 - 67,035,312 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1167,025,154 - 67,035,312 (+)EnsemblGRCm38mm10GRCm38
MGSCv371166,838,656 - 66,848,292 (+)NCBIGRCm37mm9NCBIm37
MGSCv361166,841,349 - 66,850,985 (+)NCBImm8
Celera1173,964,497 - 73,974,141 (+)NCBICelera
Cytogenetic Map11B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:16141072   PMID:16141073   PMID:18799693   PMID:21267068  


Genomics

Comparative Map Data
Tmem220
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391166,915,959 - 66,927,818 (+)NCBIGRCm39mm39
GRCm39 Ensembl1166,915,980 - 66,926,138 (+)Ensembl
GRCm381167,025,154 - 67,035,312 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1167,025,154 - 67,035,312 (+)EnsemblGRCm38mm10GRCm38
MGSCv371166,838,656 - 66,848,292 (+)NCBIGRCm37mm9NCBIm37
MGSCv361166,841,349 - 66,850,985 (+)NCBImm8
Celera1173,964,497 - 73,974,141 (+)NCBICelera
Cytogenetic Map11B3NCBI
TMEM220
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1710,699,015 - 10,730,023 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1710,699,015 - 10,730,316 (-)EnsemblGRCh38hg38GRCh38
GRCh381710,711,084 - 10,730,023 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371710,614,450 - 10,633,340 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361710,557,364 - 10,574,371 (-)NCBINCBI36hg18NCBI36
Celera1710,647,493 - 10,664,502 (-)NCBI
Cytogenetic Map17p13.1NCBI
HuRef1710,516,685 - 10,533,692 (-)NCBIHuRef
CHM1_11710,626,849 - 10,643,856 (-)NCBICHM1_1
Tmem220
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21051,719,777 - 51,728,792 (+)NCBI
Rnor_6.0 Ensembl1053,570,989 - 53,579,321 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01053,570,980 - 53,579,994 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01053,321,978 - 53,331,027 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41053,726,472 - 53,735,025 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11053,687,155 - 53,748,648 (+)NCBI
Celera1050,902,896 - 50,911,906 (+)NCBICelera
Cytogenetic Map10q24NCBI
Tmem220
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554676,487,925 - 6,503,178 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554676,487,936 - 6,503,178 (+)NCBIChiLan1.0ChiLan1.0
TMEM220
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl534,985,492 - 34,995,784 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1534,984,756 - 34,995,778 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Tmem220
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365953,552,393 - 3,567,085 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEM220
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1255,438,196 - 55,454,590 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11255,438,199 - 55,454,912 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21258,068,670 - 58,085,026 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TMEM220
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11610,054,725 - 10,072,168 (-)NCBI
Tmem220
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478613,071,316 - 13,085,721 (-)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11330000072800000Mouse
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111160000068600000Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1231863768609504Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111231863768609504Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111231863768609504Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1231863768609504Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1231863768609504Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111231863768609504Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1231863768609504Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1231863768609504Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1231863768609504Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111231863768609504Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111231863768609504Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111231863769794121Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111710617567187585Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111783196668609504Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113568778969794161Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113639175083590530Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113661246070618665Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113672273870723028Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113719011571190238Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113812528972125383Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114236579176365904Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114236579176365904Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114473921176963931Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
4141000Nidd3_mnon-insulin-dependent diabetes mellitus 3 (mouse)Not determined4515120179151308Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114527504680087498Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114629434180294436Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114642858180428696Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115018736584187585Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115260355986603559Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115349976287499911Mouse
1302186Blmpf2_mbleomycin-induced pulmonary fibrosis 2 (mouse)Not determined115417484467187585Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115423592683842826Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5539415972319101Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115786383491863932Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115859972974863932Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15861720487804412Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5882844085175703Mouse
11532697Sluc36_msusceptibility to lung cancer 36 (mouse)115936579169591873Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116179599488808902Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116226517996265327Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162700000109500000Mouse
4141642Ltxs2_mlethal factor toxin susceptibility 2 (mouse)Not determined116315128768609504Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116342858181939647Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116342858194173092Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116493951098939647Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116493951098939647Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116493951098939647Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166842594100842826Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166842594100842826Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66842594100842826Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166842594100842826Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166842594100842826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166842594100842826Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:499
Count of miRNA genes:253
Interacting mature miRNAs:284
Transcripts:ENSMUST00000061786, ENSMUST00000079077
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000061786   ⟹   ENSMUSP00000057366
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1167,025,154 - 67,035,312 (+)Ensembl
RefSeq Acc Id: ENSMUST00000079077   ⟹   ENSMUSP00000078084
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1167,025,154 - 67,034,790 (+)Ensembl
RefSeq Acc Id: NM_001291042   ⟹   NP_001277971
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391166,915,980 - 66,926,138 (+)NCBI
GRCm381167,025,154 - 67,035,312 (+)NCBI
Celera1173,964,497 - 73,981,774 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001291043   ⟹   NP_001277972
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391166,915,980 - 66,926,138 (+)NCBI
GRCm381167,025,154 - 67,035,312 (+)NCBI
Celera1173,964,497 - 73,981,774 (+)NCBI
Sequence:
RefSeq Acc Id: NM_177392   ⟹   NP_796366
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391166,915,980 - 66,926,138 (+)NCBI
GRCm381167,025,154 - 67,035,312 (+)NCBI
MGSCv371166,838,656 - 66,848,292 (+)RGD
Celera1173,964,497 - 73,981,774 (+)NCBI
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036156786   ⟹   XP_036012679
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391166,915,959 - 66,927,818 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_796366   ⟸   NM_177392
- Peptide Label: isoform 1 precursor
- UniProtKB: Q8BP07 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001277971   ⟸   NM_001291042
- Peptide Label: isoform 2
- UniProtKB: Q8BP07 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001277972   ⟸   NM_001291043
- Peptide Label: isoform 3
- UniProtKB: Q8BP07 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000078084   ⟸   ENSMUST00000079077
RefSeq Acc Id: ENSMUSP00000057366   ⟸   ENSMUST00000061786
RefSeq Acc Id: XP_036012679   ⟸   XM_036156786
- Peptide Label: isoform X1

Promoters
RGD ID:6822356
Promoter ID:MM_KWN:7923
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000079077,   OTTMUST00000013170,   UC007JLQ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361166,838,456 - 66,838,956 (+)MPROMDB
RGD ID:8675058
Promoter ID:EPDNEW_M15560
Type:multiple initiation site
Name:Tmem220_1
Description:Mus musculus transmembrane protein 220 , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381167,025,163 - 67,025,223EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2443691 AgrOrtholog
Ensembl Genes ENSMUSG00000050270 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000057366 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000078084 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000061786 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000079077 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro TMEM220 UniProtKB/Swiss-Prot
KEGG Report mmu:338369 UniProtKB/Swiss-Prot
MGD MGI:2443691 ENTREZGENE
NCBI Gene 338369 ENTREZGENE
Pfam TMEM220 UniProtKB/Swiss-Prot
PhenoGen Tmem220 PhenoGen
UniProt Q8BP07 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q2TB06 UniProtKB/Swiss-Prot
  Q8C936 UniProtKB/Swiss-Prot