Ints5 (integrator complex subunit 5)

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Gene: Ints5 (integrator complex subunit 5) Mus musculus

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Symbol:

Ints5

Name:

integrator complex subunit 5

RGD ID:

1319683

MGI Page

MGI

Description:

Predicted to be involved in snRNA 3'-end processing. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of integrator complex. Is expressed in forebrain. Orthologous to human INTS5 (integrator complex subunit 5).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

1110055N21Rik; int5; mKIAA1698

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	INTS5 (integrator complex subunit 5)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Ints5 (integrator complex subunit 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ints5 (integrator complex subunit 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	INTS5 (integrator complex subunit 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	INTS5 (integrator complex subunit 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ints5 (integrator complex subunit 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	INTS5 (integrator complex subunit 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	INTS5 (integrator complex subunit 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ints5 (integrator complex subunit 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Ints5 (integrator complex subunit 5)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	INTS5 (integrator complex subunit 5)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ints5 (integrator complex subunit 5)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Caenorhabditis elegans (roundworm):	Y51A2D.7	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	omd	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ints5	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Related Pseudogenes:

Gm13126

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	8,870,351 - 8,875,254 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	8,870,369 - 8,875,252 (+)	Ensembl		GRCm39 Ensembl
GRCm38	19	8,892,987 - 8,897,890 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	8,893,005 - 8,897,888 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	8,967,477 - 8,972,380 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	8,960,050 - 8,964,933 (+)	NCBI		MGSCv36	mm8
Celera	19	8,653,728 - 8,658,629 (+)	NCBI		Celera
Cytogenetic Map	19	A	NCBI
cM Map	19	5.95	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

intellectual disability (ISO)

Larsen-like syndrome B3GAT3 type (ISO)

leukocyte adhesion deficiency 3 (ISO)

polycystic kidney disease 3 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

1,2-dimethylhydrazine (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-hydroxypropanoic acid (ISO)

3,4-methylenedioxymethamphetamine (EXP)

acrylamide (ISO)

benzo[a]pyrene (EXP,ISO)

bisphenol A (ISO)

cadmium atom (ISO)

carbon nanotube (EXP)

clobetasol (EXP)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (EXP)

doxorubicin (ISO)

ethanol (EXP)

ethyl methanesulfonate (ISO)

fenthion (EXP)

FR900359 (ISO)

iron dichloride (ISO)

leflunomide (ISO)

methyl methanesulfonate (ISO)

paracetamol (EXP)

perfluorooctane-1-sulfonic acid (EXP)

propiconazole (EXP)

rac-lactic acid (ISO)

resveratrol (EXP)

sodium arsenite (ISO)

thiram (ISO)

vinclozolin (ISO)

vincristine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

snRNA 3'-end processing (IBA)

snRNA processing (ISO,ISS)

Cellular Component

cytoplasm (ISO,ISS)

cytosol (IEA,ISO)

integrator complex (IBA,ISO,ISS)

nuclear membrane (IEA)

nucleoplasm (IEA,ISO)

nucleus (ISO,ISS)

Molecular Function

molecular_function (ND)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:10349636	PMID:10922068	PMID:11042159	PMID:11076861	PMID:11217851	PMID:12466851	PMID:12477932	PMID:14610273	PMID:14621295	PMID:15489334	PMID:15782199
PMID:16141072	PMID:16141073	PMID:18799693	PMID:20436479	PMID:21873635	PMID:29091030	PMID:32325033

Genomics

Comparative Map Data

Ints5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	8,870,351 - 8,875,254 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	8,870,369 - 8,875,252 (+)	Ensembl		GRCm39 Ensembl
GRCm38	19	8,892,987 - 8,897,890 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	8,893,005 - 8,897,888 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	8,967,477 - 8,972,380 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	8,960,050 - 8,964,933 (+)	NCBI		MGSCv36	mm8
Celera	19	8,653,728 - 8,658,629 (+)	NCBI		Celera
Cytogenetic Map	19	A	NCBI
cM Map	19	5.95	NCBI

INTS5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	62,646,848 - 62,653,302 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	62,646,848 - 62,653,302 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	62,414,320 - 62,420,774 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	62,170,896 - 62,177,350 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	11	59,743,866 - 59,750,321 (-)	NCBI		Celera
Cytogenetic Map	11	q12.3	NCBI
HuRef	11	58,743,216 - 58,749,671 (-)	NCBI		HuRef
CHM1_1	11	62,297,383 - 62,303,837 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	62,636,300 - 62,642,755 (-)	NCBI		T2T-CHM13v2.0

Ints5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	215,218,012 - 215,222,790 (+)	NCBI		GRCr8
mRatBN7.2	1	205,788,906 - 205,793,685 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	205,788,906 - 205,793,685 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	214,197,342 - 214,202,157 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	221,232,289 - 221,237,067 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	213,925,134 - 213,929,912 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	225,091,612 - 225,096,390 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	225,091,612 - 225,096,390 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	232,029,232 - 232,034,010 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	211,568,313 - 211,573,091 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	211,726,742 - 211,731,524 (+)	NCBI
Celera	1	203,301,678 - 203,306,456 (+)	NCBI		Celera
Cytogenetic Map	1	q43	NCBI

Ints5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955599	551,078 - 556,341 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955599	551,989 - 556,341 (+)	NCBI	ChiLan1.0	ChiLan1.0

INTS5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	63,873,745 - 63,880,233 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	64,916,353 - 64,922,928 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	58,004,058 - 58,010,526 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	61,358,029 - 61,364,549 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	61,358,029 - 61,364,549 (-)	Ensembl	panpan1.1		panPan2

INTS5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	53,998,828 - 54,004,127 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	53,998,897 - 54,003,957 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	52,603,878 - 52,609,166 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	55,051,324 - 55,056,844 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	55,051,335 - 55,056,674 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	54,147,237 - 54,152,524 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	53,722,566 - 53,727,856 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	54,517,953 - 54,523,246 (+)	NCBI		UU_Cfam_GSD_1.0

Ints5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	10,493,549 - 10,499,261 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936581	607,079 - 613,161 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936581	607,253 - 613,080 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

INTS5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	9,095,633 - 9,100,307 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	9,095,646 - 9,100,487 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	8,441,394 - 8,446,234 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

INTS5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	11,251,920 - 11,257,686 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	11,251,991 - 11,257,520 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	108,586,766 - 108,592,540 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ints5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624926	1,160,935 - 1,165,414 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624926	1,160,997 - 1,165,451 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ints5
129 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	73
Count of miRNA genes:	67
Interacting mature miRNAs:	73
Transcripts:	ENSMUST00000096249
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4142302	Nstr1_m	nerve sheath tumor resistance QTL 1 (mouse)			Not determined		19	1	22371338	Mouse
1301271	Datd_m	dopamine transporter density (mouse)			Not determined		19	1	32340234	Mouse
1300923	Bits4_m	bitterness sensitivity 4 (mouse)			Not determined		19	3323216	37323348	Mouse
11039522	Tbbr4_m	Trypanosoma brucei brucei response 4 (mouse)					19	5313326	39313470	Mouse
25394536	Skmw86_m	skeletal muscle weight 86, TA (mouse)					19	5064817	8957825	Mouse
4142161	Drinksac2_m	drink saccharin 2 (mouse)			Not determined			1	20695286	Mouse
1357819	Tgct2_m	testicular germ cell tumor 2 (mouse)			Not determined		19	3328551	20539663	Mouse
4142406	Pbctlp1_m	peripheral blood cytotoxic T lymphocyte percentage 1 (mouse)			Not determined			1	32875174	Mouse
1300776	Lfp3_m	long free running period 3 (mouse)			Not determined		19	1	20328703	Mouse
1300904	Chab5_m	cholesterol absorption 5 (mouse)			Not determined		19	1653764	35653927	Mouse
26884385	Skwq14_m	skull length QTL 14, 16 week (mouse)					19	3250000	35877400	Mouse
1301800	Faq10_m	fluctuating asymmetry QTL 10 (mouse)			Not determined		19	3323216	37323348	Mouse
1300591	Pas3_m	pulmonary adenoma susceptibility 3 (mouse)			Not determined		19	3323216	37323348	Mouse
1302126	Skull26_m	skull morphology 26 (mouse)			Not determined		19	3323216	37323348	Mouse

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_176843	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC129217	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK075663	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK143868	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK144770	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK155499	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK166149	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK168795	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK170584	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK172260	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK179137	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK179191	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK179344	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK181213	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK183009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK183329	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK183632	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK217710	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC039214	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BY152900	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BY546950	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466612	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000096249 ⟹ ENSMUSP00000093968

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	19	8,870,369 - 8,875,252 (+)	Ensembl
GRCm38.p6 Ensembl	19	8,893,005 - 8,897,888 (+)	Ensembl

RefSeq Acc Id:

NM_176843 ⟹ NP_789813

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	19	8,870,351 - 8,875,254 (+)	NCBI
GRCm38	19	8,892,987 - 8,897,890 (+)	ENTREZGENE
MGSCv37	19	8,967,477 - 8,972,380 (+)	RGD
Celera	19	8,653,728 - 8,658,629 (+)	RGD
cM Map	19		ENTREZGENE

Sequence:

show sequence

GTTTCTGTCGCGTTTCCAGTCAGCACGCATGCGTCGCCTGTGCTCCGCCGCTCCCGCCTCAGGC
TCCGGGTAGGGCTCCGGGATGTCCGCGTTGTGCGACCCTCCCGGGGCCCCAGGGCCACCCGGGC
CTGCCCCCGCCACCCACGGTCCCGCGCCTCTCAGTGCTCAGGAGCTGTCCCAAGAAATCAAGGC
TTTTTTGACCGGTGTAGACCCTATTCTGGGCCACCAGCTCTCAGCTCGTGAACATGCTCGATGT
GGTCTTCTCTTGCTCCGTTCTTTGCCACCTGCTCGGGCTGCTGTGTTGGACCACTTGAGAGGTG
TTTTTGATGAGAGTGTCCGGGCCCACCTAGCTGCCCTAGAAGAAAGTCCTGTGGCTGGTCCACC
TCACCTCCGTCCACCTCCACCATCCCATGTCCCTACTGGTGGACCTGGCTTAGAGGATGTGGTG
CATGAAGTGCAGCAGGTGCTGTGTGAGTTTATCCGGGCCAACCCAAAGGCCTGGGCACCCGTGA
TTAGTGCATGGTCCATTGACCTCATGGGACAACTGAGCAGCACATATTCAGGTCAGCATCAGCG
TGTTCCCCATGCCACTGGCTCTCTCAATGAACTGCTGCAGCTGTGGATGGGCTGCAGGGCCACC
CGCACATTAATGGACATCTATGTGCAGTGCCTCTCGGCCCTCATTGGTAGCTGCCCAGATGCAT
GTGTGGATGCCTTGCTAGACACTTCTGTCCAGCATTCCCCACACTTTGACTGGGTTGTGGCCCA
TATTGGCTCTTCTTTTCCTGGCACCATCATCTCCCGAGTCCTATCTTGTGGCCTTAAGGACTTC
TGTGTCCATAGTGGGGCTGGAGGAGGAGCTAGTGCTTGTGGAAACTCTTCTCAACCCCCCTCTA
CAGACCCCTTCCCTGGATCTCCTGCCATCCCTGGGGAAAAACGGGTACCCAAGATTGCCTCAGT
TGTAGGCATCCTAGGGCACCTGGCTTCCCGCCATGGAGACAGCATCCGACGGGAACTGTTGCGC
ATGTTTCATGATAGTTTGGCAGGGGGTTCTGGGGGCCGGAATGGAGAGCCCTCTCTTCAGGCCA
CAGTTCCCTTCCTACTGCAGCTGGCAGTCATGTCACCAGCTTTGCTCGGCACAGTATCTGGAGA
ACTTGTGGACTGCCTCAAGCCCCCAGCAGTGCTAAGCCAGCTGCAACAACACCTGCAGGGGTTC
CCCAGAGAAGAGCTAGACAACATGCTAAACCTGGCTGTGCATCTAGTGAGCCAGGCCTCTGGGA
CTGGTGCCTACCGCCTGCTGCAGTTCTTAGTAGACACAGCTATGCCTGCTTCAGTTATTACTAC
CCAGGGCCTGGCTGTGCCAGACACCGTGAGAGAGGCCTGTGACCGGCTGATCCAGCTGCTATTG
CTACATCTACAAAAACTAGTTCATCATCGGGGAGGGTCTCCTGGAGAAGGGGTGCTGGGCCCAC
CCCCACCTCCTCGTCCAGTGCCCTTTCTTGATGCATTACGAAACCATGTTGGAGAACTGTGTGG
AGAGACATTACGGCTAGAACGGAAGCGCTTCCTCTGGCAACACCAGCTCCTGGGCCTACTGTCT
GTCTATACACGACCTAGCTGTGGACCTGAGGCCTTGGGTCATCTACTGAGCAGAGCCAGAAGCC
CTGAAGAGTTGAGTTTGGCAACCCAGCTATATGCAGGGCTAGTGGTCAGTCTCTCTGGCCTTCT
TCCCCTGGCCTTCCGAAGCTGCCTGGCTCGAGTGCATGCAGGGACTTTACAGCCTCCCTTCACA
GCCCGGTTTCTTCGAAATTTGGCCTTGTTGGTGGGGTGGGAGCAGCAGGGTGGTGAGGGCCCTT
CAGCCTTAGGGGCCCGGTTTGGGGAGTCTGCCTCAGCTCACCTGGCTGATCTGGCTCCTCTCCT
ACTACACCCAGAGGAGGAAGTAGCTGAAGCTGCTGCCTCCCTCCTTGCAATATGTCCCTTTCCT
TCTGAAGCCCTGTCCCCTTCCCAACTATTGGGACTAGTGAGAGCTGGAGTACACCACTTCTTCT
CTTCTCTAAGGCTGCATGGCCCTCCTGGTGTGGCTTCAGCCTCTCAGCTTCTTACCCGCCTTTC
TCAGACTTCCCCAGCTGGGCTCAAGGCTGTCCTACAGCTGCTTGTAGAGGGAGCCTTACATCGG
GGCAACACAGAACTATTTGGAGGGGAAATGGATGGAGACAATGAGACCCTCTCAATTGTCTCAA
CCCCTTTGGCTTCTGCCTCATTGTTGGACATTAACCGGAGGCATACTGCAGCAGTGCCGGGTCC
TGGAGGGATCTGGTCAGTTTTCCATGCTGGAGTTATCGGCCGTGGCTTAAAGCCACCTAAAATT
GTTCAATCTCGAAACCATCAAGAAGTGATCTATAACACCCAGAGCCTCGTTAGCCTCCTAGTGC
ACTGCTGCAGCGCATCAGGGAACAGCGAGCGTGAGGGTTGCTGGGGGGCTCCCACCCTGAGCCC
AGAGGCAGCCAAAGCAGTTGCGGTGACCTTAGTGGAGAGCGTGTGTCCTGATGCAGCTGGTGCT
GAGCTGGCCTGGCCCCCAGAGGATCATGCACGAGCCACCGTGGAGCGGGATCTCCGAATTGGTA
GGCGCTTCCGGGAACAACCTCTGCTGTTTGAGCTTTTGAAGCTGGTAGCAGCTGCTCCCCCAGC
CCTGTGCTACTGCTCCGTGCTGCTGCGGGGGCTGCTGGCTGCCCTCTTGAGCCATTGGGAAGCC
TCTCGACACCCTGATACAACCCACTCCCCCTGGCATCTGGAGGCATCCTGTATCCTGGTGGCTG
TCATGGCTGAGGGAAGCCTCTTGCCACCAGCCCTGGGTAATATGCACGAGGTATTTAGCCAACT
GGCACCTTTTGAAGTGCGTCTGTTGCTGCTTAGTGTCTGGGGTTTTCTTCGGGAGCATGGGCCC
TTGCCCCAGAAGTTCATCTTCCAGTCTGAACGTGGCCGCTTCATCCGGGACTTTGCCAGGGAGG
GTGGAGCTGAAGGAGGACCACATCTGTCTGTGCTGCACAGTGTCCTCCACCGCAACATCGATCG
CCTGGGGCTCTTCTCTGGCCGCTTTCAAGCACCTCCGCCATCCACTCTGCTTCGGCAGGGGACT
TGACCTTTTCTCTACAAGTTGTGCGAGGTTAAACTGAGAGAAGAGCCTAAGGTGCTACAGAAGG
GTGGATGCTTCTAAGTCCGTACGTAATGAGTGGTGTCACTTTTTTCAAACCCCACCATTTTTTC
TAAATAAAATTTGCCGAGTTGAGACAAACA

hide sequence

Protein Sequences


Protein RefSeqs	NP_789813	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH39214	(Get FASTA)	NCBI Sequence Viewer
	BAE33294	(Get FASTA)	NCBI Sequence Viewer
	BAE38598	(Get FASTA)	NCBI Sequence Viewer
	BAE40628	(Get FASTA)	NCBI Sequence Viewer
	BAE41894	(Get FASTA)	NCBI Sequence Viewer
	EDL33397	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000093968
	ENSMUSP00000093968.6
GenBank Protein	Q8CHT3	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_789813 ⟸ NM_176843

- UniProtKB:

Q8CHT3 (UniProtKB/Swiss-Prot), Q3TM44 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MSALCDPPGAPGPPGPAPATHGPAPLSAQELSQEIKAFLTGVDPILGHQLSAREHARCGLLLLR
SLPPARAAVLDHLRGVFDESVRAHLAALEESPVAGPPHLRPPPPSHVPTGGPGLEDVVHEVQQV
LCEFIRANPKAWAPVISAWSIDLMGQLSSTYSGQHQRVPHATGSLNELLQLWMGCRATRTLMDI
YVQCLSALIGSCPDACVDALLDTSVQHSPHFDWVVAHIGSSFPGTIISRVLSCGLKDFCVHSGA
GGGASACGNSSQPPSTDPFPGSPAIPGEKRVPKIASVVGILGHLASRHGDSIRRELLRMFHDSL
AGGSGGRNGEPSLQATVPFLLQLAVMSPALLGTVSGELVDCLKPPAVLSQLQQHLQGFPREELD
NMLNLAVHLVSQASGTGAYRLLQFLVDTAMPASVITTQGLAVPDTVREACDRLIQLLLLHLQKL
VHHRGGSPGEGVLGPPPPPRPVPFLDALRNHVGELCGETLRLERKRFLWQHQLLGLLSVYTRPS
CGPEALGHLLSRARSPEELSLATQLYAGLVVSLSGLLPLAFRSCLARVHAGTLQPPFTARFLRN
LALLVGWEQQGGEGPSALGARFGESASAHLADLAPLLLHPEEEVAEAAASLLAICPFPSEALSP
SQLLGLVRAGVHHFFSSLRLHGPPGVASASQLLTRLSQTSPAGLKAVLQLLVEGALHRGNTELF
GGEMDGDNETLSIVSTPLASASLLDINRRHTAAVPGPGGIWSVFHAGVIGRGLKPPKIVQSRNH
QEVIYNTQSLVSLLVHCCSASGNSEREGCWGAPTLSPEAAKAVAVTLVESVCPDAAGAELAWPP
EDHARATVERDLRIGRRFREQPLLFELLKLVAAAPPALCYCSVLLRGLLAALLSHWEASRHPDT
THSPWHLEASCILVAVMAEGSLLPPALGNMHEVFSQLAPFEVRLLLLSVWGFLREHGPLPQKFI
FQSERGRFIRDFAREGGAEGGPHLSVLHSVLHRNIDRLGLFSGRFQAPPPSTLLRQGT

hide sequence

Ensembl Acc Id:

ENSMUSP00000093968 ⟸ ENSMUST00000096249

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8CHT3-F1-model_v2	AlphaFold	Q8CHT3	1-1018	view protein structure

Promoters

RGD ID:

13678842

Promoter ID:

EPDNEW_M23570

Type:

initiation region

Name:

Ints5_1

Description:

Mus musculus integrator complex subunit 5 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	19	8,893,015 - 8,893,075	EPDNEW

RGD ID:

6830133

Promoter ID:

MM_KWN:26319

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day6, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6

Transcripts:

NM_176843

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	19	8,967,426 - 8,967,972 (+)	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1923578	AgrOrtholog
Ensembl Genes	ENSMUSG00000071652	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000096249	ENTREZGENE
	ENSMUST00000096249.7	UniProtKB/Swiss-Prot
InterPro	INTS5	UniProtKB/Swiss-Prot
	INTS5_C	UniProtKB/Swiss-Prot
	INTS5_N	UniProtKB/Swiss-Prot
KEGG Report	mmu:109077	UniProtKB/Swiss-Prot
MGD	MGI:1923578	ENTREZGENE
NCBI Gene	Ints5	ENTREZGENE
PANTHER	INTEGRATOR COMPLEX SUBUNIT 5	UniProtKB/Swiss-Prot
	PTHR31697	UniProtKB/Swiss-Prot
Pfam	INTS5_C	UniProtKB/Swiss-Prot
	INTS5_N	UniProtKB/Swiss-Prot
PhenoGen	Ints5	PhenoGen
UniProt	INT5_MOUSE	UniProtKB/Swiss-Prot
	Q3TM44	ENTREZGENE
	Q8CHT3	ENTREZGENE
UniProt Secondary	Q3TM44	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2024-08-26	Ints5	integrator complex subunit 5	1110055N21Rik	RIKEN cDNA 1110055N21 gene	Symbol and/or name updated	27372883	PROVISIONAL
2024-08-21	1110055N21Rik	RIKEN cDNA 1110055N21 gene	Ints5	integrator complex subunit 5	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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