Hus1 (HUS1 checkpoint clamp component) - Rat Genome Database

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Gene: Hus1 (HUS1 checkpoint clamp component) Mus musculus
Analyze
Symbol: Hus1
Name: HUS1 checkpoint clamp component
RGD ID: 1318031
MGI Page MGI
Description: Involved in double-strand break repair via homologous recombination; embryo development; and regulation of protein phosphorylation. Acts upstream of or within DNA damage checkpoint signaling; protein phosphorylation; and response to UV. Predicted to be located in nucleus. Predicted to be part of checkpoint clamp complex. Predicted to be active in site of double-strand break. Is expressed in several structures, including brain; exocrine system; gonad; hemolymphoid system gland; and liver. Orthologous to human HUS1 (HUS1 checkpoint clamp component).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: checkpoint protein HUS1; Hus1 homolog; mHus1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39118,943,137 - 8,961,240 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl118,943,137 - 8,961,191 (-)EnsemblGRCm39 Ensembl
GRCm38118,993,137 - 9,011,236 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl118,993,137 - 9,011,191 (-)EnsemblGRCm38mm10GRCm38
MGSCv37118,893,145 - 8,911,140 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36118,893,145 - 8,911,140 (-)NCBIMGSCv36mm8
Celera119,425,958 - 9,443,972 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map115.74NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Hus1Mousepleomorphic xanthoastrocytoma  ISORGD:13180308554872ClinVar Annotator: match by term: Pleomorphic xanthoastrocytomaClinVarPMID:28299358

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Hus1Mouse1,2-dimethylhydrazine decreases expressionEXP 64804641,2-Dimethylhydrazine results in decreased expression of HUS1 mRNACTDPMID:22206623
Hus1Mouse17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expressionISORGD:13180306480464Metribolone results in increased expression of HUS1 mRNACTDPMID:19318562
Hus1Mouse2,2',4,4'-Tetrabromodiphenyl ether decreases expressionISORGD:159197664804642,2',4,4'-tetrabromodiphenyl ether results in decreased expression of HUS1 mRNACTDPMID:27291303
Hus1Mouse2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of HUS1 mRNACTDPMID:15310856
Hus1Mouse2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of HUS1 mRNACTDPMID:21570461
Hus1Mouse3,4-methylenedioxymethamphetamine decreases expressionEXP 6480464N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of HUS1 mRNACTDPMID:26251327
Hus1Mouse4-hydroxynon-2-enal decreases expressionEXP 64804644-hydroxy-2-nonenal results in decreased expression of HUS1 mRNACTDPMID:19191707
Hus1Mouseamiodarone increases expressionISORGD:13180306480464Amiodarone results in increased expression of HUS1 mRNACTDPMID:19774075
Hus1Mousearistolochic acid A decreases expressionISORGD:13180306480464aristolochic acid I results in decreased expression of HUS1 mRNACTDPMID:33212167
Hus1Mousearsane affects methylationISORGD:13180306480464Arsenic affects the methylation of HUS1 geneCTDPMID:25304211
Hus1Mousearsenic atom affects methylationISORGD:13180306480464Arsenic affects the methylation of HUS1 geneCTDPMID:25304211
Hus1Mousearsenite(3-) multiple interactionsISORGD:13180306480464arsenite promotes the reaction [G3BP1 protein binds to HUS1 mRNA]CTDPMID:32406909
Hus1Mousearsenous acid increases expressionISORGD:13180306480464Arsenic Trioxide results in increased expression of HUS1 mRNACTDPMID:22521957
Hus1Mouseatrazine increases expressionISORGD:13180306480464Atrazine results in increased expression of HUS1 mRNACTDPMID:22378314
Hus1Mousebelinostat increases expressionEXP 6480464belinostat results in increased expression of HUS1 mRNACTDPMID:29733868
Hus1Mousebenzo[a]pyrene affects methylationISORGD:13180306480464Benzo(a)pyrene affects the methylation of HUS1 promoterCTDPMID:27901495
Hus1Mousebis(2-ethylhexyl) phthalate increases expressionEXP 6480464Diethylhexyl Phthalate results in increased expression of HUS1 mRNACTDPMID:34319233
Hus1Mousebisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of HUS1 mRNACTDPMID:21932408
Hus1Mousebisphenol A increases methylationISORGD:15919766480464bisphenol A results in increased methylation of HUS1 geneCTDPMID:28505145
Hus1Mousebisphenol A affects expressionISORGD:15919766480464bisphenol A affects the expression of HUS1 mRNACTDPMID:25181051

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Biological Process
1 to 18 of 18 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Hus1Mousecellular response to ionizing radiation involved_inIEAUniProtKB:O60921|ensembl:ENSP000002587742290270 EnsemblGO_REF:0000107
Hus1Mousecellular response to ionizing radiation involved_inISOUniProtKB:O609212290270 GO_CentralGO_REF:0000119
Hus1MouseDNA damage checkpoint signaling acts_upstream_of_or_withinIMPMGI:19277692290270 PMID:12529385MGIPMID:12529385
Hus1MouseDNA damage checkpoint signaling involved_inISOUniProtKB:O609212290270 GO_CentralGO_REF:0000119
Hus1MouseDNA damage response acts_upstream_of_or_withinIDA 2290270 PMID:11790307MGIPMID:11790307
Hus1Mousedouble-strand break repair via homologous recombination involved_inIBAPANTHER:PTN000307391|FB:FBgn0026417|MGI:12779622290270 GO_CentralGO_REF:0000033
Hus1Mousedouble-strand break repair via homologous recombination involved_inIDA 2290270 PMID:16278671UniProtPMID:16278671
Hus1Mouseembryo development ending in birth or egg hatching involved_inIMP 2290270 PMID:15919177UniProtPMID:15919177
Hus1Mousemeiotic DNA integrity checkpoint signaling involved_inIBAPANTHER:PTN000307391|FB:FBgn00264172290270 GO_CentralGO_REF:0000033
Hus1Mousemitotic DNA replication checkpoint signaling involved_inIBAPANTHER:PTN000307391|PomBase:SPAC20G4.04c2290270 GO_CentralGO_REF:0000033
Hus1Mousemitotic intra-S DNA damage checkpoint signaling involved_inIBAPANTHER:PTN000307391|PomBase:SPAC20G4.04c2290270 GO_CentralGO_REF:0000033
Hus1Mousenucleotide-excision repair involved_inIBAPANTHER:PTN000307391|WB:WBGene000020422290270 GO_CentralGO_REF:0000033
Hus1Mouseprotein phosphorylation acts_upstream_of_or_withinIDA 2290270 PMID:11790307MGIPMID:11790307
Hus1Mouseprotein phosphorylation acts_upstream_of_or_withinIMPMGI:19277692290270 PMID:12529385MGIPMID:12529385
Hus1Mouseregulation of protein phosphorylation involved_inIMP 2290270 PMID:12676962UniProtPMID:12676962
Hus1Mouseresponse to UV acts_upstream_of_or_withinIMPMGI:19277692290270 PMID:12529385MGIPMID:12529385
Hus1Mouseresponse to UV acts_upstream_of_or_withinIDA 2290270 PMID:11790307MGIPMID:11790307
Hus1Mousetelomere maintenance involved_inIBAPANTHER:PTN000307391|WB:WBGene00002042|SGD:S000004279|PomBase:SPAC20G4.04c2290270 GO_CentralGO_REF:0000033
1 to 18 of 18 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Hus1Mousecheckpoint clamp complex part_ofIBAPANTHER:PTN000307391|SGD:S000004279|UniProtKB:O60921|FB:FBgn0026417|PomBase:SPAC20G4.04c2290270 GO_CentralGO_REF:0000033
Hus1Mousecheckpoint clamp complex part_ofISOUniProtKB:O609212290270 GO_CentralGO_REF:0000119
Hus1Mousecheckpoint clamp complex part_ofIEAUniProtKB:O60921|ensembl:ENSP000002587742290270 EnsemblGO_REF:0000107
Hus1Mousecytosol located_inIEAUniProtKB-SubCell:SL-00912290270 UniProtGO_REF:0000044
Hus1Mousenucleolus located_inIEAInterPro:IPR0165802290270 InterProGO_REF:0000002
Hus1Mousenucleus located_inISSUniProtKB:O609212290270 UniProtGO_REF:0000024
Hus1Mousenucleus located_inISOUniProtKB:O609212290270 GO_CentralGO_REF:0000119
Hus1Mousesite of double-strand break is_active_inIBAPANTHER:PTN000307391|PomBase:SPAC20G4.04c2290270 GO_CentralGO_REF:0000033

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Hus1Mouseprotein binding enablesISOUniProtKB:O60671|UniProtKB:Q996389068941 PMID:10359610, PMID:14624239, PMID:19464297, PMID:33961781, PMID:35271311IntActPMID:10359610|PMID:14624239|PMID:19464297|PMID:33961781|PMID:35271311
Hus1Mouseprotein binding enablesISOUniProtKB:Q996389068941 PMID:28514442IntActPMID:28514442
Hus1Mouseprotein binding enablesISOUniProtKB:P55042|UniProtKB:Q996389068941 PMID:10359610UniProtPMID:10359610
Hus1Mouseprotein binding enablesISOUniProtKB:O00560|UniProtKB:Q504U0|UniProtKB:Q96HA8|UniProtKB:Q99638|UniProtKB:Q9BTE7|UniProtKB:Q9Y3R0-39068941 PMID:32296183IntActPMID:32296183
Hus1Mouseprotein binding enablesISOUniProtKB:Q135479068941 PMID:10846170UniProtPMID:10846170
Hus1Mouseprotein binding enablesISOUniProtKB:O759439068941 PMID:10884395UniProtPMID:10884395

1 to 20 of 43 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Hus1Mouseabnormal allantois morphology  IAGP 5509061 MGIPMID:10921903
Hus1Mouseabnormal cell cycle checkpoint function  IAGP 5509061 MGIPMID:17220276
Hus1Mouseabnormal cell physiology  IAGP 5509061 MGIPMID:17220276
Hus1Mouseabnormal chromosome morphology  IAGP 5509061 MGIPMID:17220276
Hus1Mouseabnormal developmental patterning  IAGP 5509061 MGIPMID:15919177
Hus1Mouseabnormal embryo turning  IAGP 5509061 MGIPMID:15919177
Hus1Mouseabnormal embryonic hematopoiesis  IAGP 5509061 MGIPMID:10921903
Hus1Mouseabnormal neural tube morphology  IAGP 5509061 MGIPMID:15919177
Hus1Mouseabnormal placenta labyrinth morphology  IAGP 5509061 MGIPMID:10921903
Hus1Mouseabnormal placental labyrinth vasculature morphology  IAGP 5509061 MGIPMID:10921903
Hus1Mouseabnormal somite development  IAGP 5509061 MGIPMID:10921903
Hus1Mouseabnormal somite development  IAGP 5509061 MGIPMID:15919177
Hus1Mouseabnormal somite shape  IAGP 5509061 MGIPMID:10921903
Hus1Mouseabnormal visceral yolk sac blood island morphology  IAGP 5509061 MGIPMID:10921903
Hus1Mouseabnormal visceral yolk sac morphology  IAGP 5509061 MGIPMID:10921903
Hus1Mouseabnormal vitelline vasculature morphology  IAGP 5509061 MGIPMID:10921903
Hus1Mouseabnormal vitelline vasculature morphology  IAGP 5509061 MGIPMID:15919177
Hus1Mouseabsent fibroblast proliferation  IAGP 5509061 MGIPMID:10921903
Hus1Mouseabsent limb buds  IAGP 5509061 MGIPMID:10921903
Hus1Mousechromosome breakage  IAGP 5509061 MGIPMID:10921903
1 to 20 of 43 rows

#
Reference Title
Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. MGD IEA MGD IEA
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:9524127   PMID:9878245   PMID:10349636   PMID:10395797   PMID:10871397   PMID:10921903   PMID:10922068   PMID:10964515   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11790307  
PMID:11944979   PMID:12477932   PMID:12529385   PMID:12676962   PMID:14610273   PMID:15485898   PMID:15489334   PMID:15919177   PMID:16141072   PMID:16141073   PMID:16278671   PMID:16890531  
PMID:17015433   PMID:17215515   PMID:17220276   PMID:19918068   PMID:21267068   PMID:21873635   PMID:22560297   PMID:22575700   PMID:23468651   PMID:23975433   PMID:25911100   PMID:25915840  
PMID:33137086   PMID:34746147  



Hus1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39118,943,137 - 8,961,240 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl118,943,137 - 8,961,191 (-)EnsemblGRCm39 Ensembl
GRCm38118,993,137 - 9,011,236 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl118,993,137 - 9,011,191 (-)EnsemblGRCm38mm10GRCm38
MGSCv37118,893,145 - 8,911,140 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36118,893,145 - 8,911,140 (-)NCBIMGSCv36mm8
Celera119,425,958 - 9,443,972 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map115.74NCBI
HUS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38747,963,288 - 47,979,615 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl747,961,882 - 47,979,615 (-)EnsemblGRCh38hg38GRCh38
GRCh37748,002,885 - 48,019,212 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36747,970,308 - 47,985,771 (-)NCBINCBI36Build 36hg18NCBI36
Build 34747,777,022 - 47,792,486NCBI
Celera748,103,051 - 48,118,524 (-)NCBICelera
Cytogenetic Map7p12.3NCBI
HuRef747,888,421 - 47,904,763 (-)NCBIHuRef
CHM1_1748,006,647 - 48,022,950 (-)NCBICHM1_1
T2T-CHM13v2.0748,125,574 - 48,141,862 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2748,042,830 - 48,059,174 (-)NCBI
Hus1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81487,902,458 - 87,917,221 (-)NCBIGRCr8
mRatBN7.21483,688,702 - 83,703,466 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1483,688,708 - 83,703,442 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1488,078,925 - 88,093,608 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01489,318,825 - 89,333,508 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01485,785,994 - 85,800,673 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01489,194,086 - 89,208,825 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1489,194,092 - 89,208,825 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01488,991,462 - 89,006,201 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41489,527,997 - 89,542,730 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1482,724,930 - 82,739,682 (-)NCBICelera
Cytogenetic Map14q21NCBI
Hus1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554565,465,182 - 5,474,303 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554565,465,180 - 5,476,380 (+)NCBIChiLan1.0ChiLan1.0
HUS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2652,827,109 - 52,856,425 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17101,151,875 - 101,181,134 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0748,606,848 - 48,622,194 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1748,714,028 - 48,731,038 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl748,714,668 - 48,731,005 (-)Ensemblpanpan1.1panPan2
HUS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11693,596 - 104,908 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1693,626 - 125,597 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha16865,769 - 879,528 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01671,091 - 84,888 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2475,012 - 112,036 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11665,830 - 79,607 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.016811 - 14,587 (+)NCBIUNSW_CanFamBas_1.0
Hus1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118103,172,833 - 103,202,691 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647822,400,111 - 22,414,115 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647822,393,952 - 22,414,349 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HUS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1848,522,998 - 48,534,682 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11848,522,914 - 48,539,267 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
HUS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12110,826,799 - 10,841,579 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2110,826,846 - 10,841,382 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606211,380,792 - 11,397,402 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hus1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247405,606,129 - 5,618,092 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247405,606,828 - 5,617,848 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Hus1
747 total Variants

Predicted Target Of
Summary Value
Count of predictions:3070
Count of miRNA genes:801
Interacting mature miRNAs:1043
Transcripts:ENSMUST00000020683, ENSMUST00000127578, ENSMUST00000129115, ENSMUST00000139877, ENSMUST00000146002, ENSMUST00000152890
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 25 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
1302171Pgia28_mproteoglycan induced arthritis 28 (mouse)Not determined11890609742906218Mouse
1357722Vtbt11_mvertebral trabecular bone trait 11 (mouse)Not determined11123880487Mouse
1301765Skull15_mskull morphology 15 (mouse)Not determined11125976374Mouse
1357518Tgyl1_mtriglyceride level 1 (mouse)Not determined11688027733916219Mouse
1300599Cocrb11_mcocaine related behavior 11 (mouse)Not determined11267035536671472Mouse
1300661Lmr6_mleishmaniasis resistance 6 (mouse)Not determined11125976374Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
27095925Pglq5_mpelvic girdle length QTL 5, 5 week (mouse)11325000019750000Mouse

1 to 10 of 25 rows
AF076845  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38118,996,766 - 8,996,859UniSTSGRCm38
MGSCv37118,896,769 - 8,896,862UniSTSGRCm37
Celera119,429,582 - 9,429,675UniSTS
Cytogenetic Map11A1UniSTS
cM Map113.0UniSTS
Whitehead/MRC_RH1143.67UniSTS
D10Mit157.2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6D1UniSTS
Cytogenetic Map16B4UniSTS
Cytogenetic Map18E2UniSTS
Cytogenetic Map4C3UniSTS
Cytogenetic Map7B2UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map11E1UniSTS
Cytogenetic Map14E2.2UniSTS
Cytogenetic Map4C7UniSTS
Cytogenetic Map2H4UniSTS
Cytogenetic Map1FUniSTS
Cytogenetic Map6C3UniSTS
Cytogenetic Map11DUniSTS
Cytogenetic Map3G2UniSTS
Cytogenetic Map17A1UniSTS
Cytogenetic Map9F2UniSTS
Cytogenetic Map12F1UniSTS
Cytogenetic Map19C2UniSTS
Cytogenetic Map3BUniSTS
Cytogenetic Map8C1UniSTS
Cytogenetic Map18A2UniSTS
Cytogenetic Map3F2UniSTS
Cytogenetic Map14C3UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map8E2UniSTS
Cytogenetic Map5B1UniSTS
Cytogenetic Map18B1UniSTS
Cytogenetic Map9CUniSTS
Cytogenetic Map14C2UniSTS
Cytogenetic Map6A1UniSTS
Cytogenetic Map10B4UniSTS
Cytogenetic Map13D2.1UniSTS
Cytogenetic Map5E5UniSTS
Cytogenetic Map11B1.3UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map9A5.2UniSTS
Cytogenetic Map3F1UniSTS
Cytogenetic Map17E3UniSTS
Cytogenetic Map11B3UniSTS
Cytogenetic Map1H4UniSTS
Cytogenetic Map6A3UniSTS
Cytogenetic Map5E4-E5UniSTS
Cytogenetic Map15E1UniSTS
Cytogenetic Map13DUniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map14D1UniSTS
Cytogenetic Map7B4UniSTS
Cytogenetic Map8D3UniSTS
Cytogenetic MapXDUniSTS
Cytogenetic Map17A3.3UniSTS
Cytogenetic Map7E2UniSTS
Cytogenetic Map1H2.3UniSTS
Cytogenetic Map7A2UniSTS
Cytogenetic Map7F3UniSTS
Cytogenetic Map9F1UniSTS
Cytogenetic Map10C1UniSTS
Cytogenetic Map4E2UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map8D2UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map15D2UniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map7A3UniSTS
Cytogenetic Map15F1UniSTS
Cytogenetic Map16B2UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map3F2.1UniSTS
Cytogenetic Map6F3UniSTS
Cytogenetic Map1C4UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map9F3UniSTS
Cytogenetic Map2BUniSTS
Cytogenetic Map13B3UniSTS
Cytogenetic Map9A4UniSTS
Cytogenetic Map5A3UniSTS
Cytogenetic Map2H1UniSTS
Cytogenetic Map16B1UniSTS
Cytogenetic Map1A5UniSTS
Cytogenetic Map11CUniSTS
Cytogenetic Map9E1UniSTS
Cytogenetic Map6G1UniSTS
Cytogenetic MapXA2UniSTS
Cytogenetic Map13B1UniSTS
Cytogenetic Map5E2UniSTS
Cytogenetic Map12C1UniSTS
Cytogenetic Map5FUniSTS
Cytogenetic Map4D3UniSTS
Cytogenetic Map10C2UniSTS
Cytogenetic Map9BUniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map7F1UniSTS
Cytogenetic Map12C3UniSTS
Cytogenetic Map10A4UniSTS
Cytogenetic Map8A2UniSTS
Cytogenetic Map18A1UniSTS
Cytogenetic Map12A1.1UniSTS
Cytogenetic Map1C2UniSTS
Cytogenetic Map11B2UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map5C3.3UniSTS
Cytogenetic Map1BUniSTS
Cytogenetic Map17A3.1UniSTS
Cytogenetic Map7A1UniSTS
Cytogenetic Map2E5UniSTS
Cytogenetic Map11A1UniSTS
Cytogenetic Map4B1UniSTS
Cytogenetic Map15A2UniSTS
Cytogenetic Map8C3UniSTS
Cytogenetic Map2A3UniSTS
Cytogenetic Map5G3UniSTS
Cytogenetic Map4A3UniSTS
Cytogenetic Map2H3UniSTS
Cytogenetic Map8A1UniSTS
Cytogenetic Map8A1.1UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map10B1UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map10A1UniSTS
Cytogenetic Map13D1UniSTS
Cytogenetic Map4A1UniSTS
Cytogenetic Map9A3UniSTS
Cytogenetic Map17CUniSTS
Cytogenetic Map1DUniSTS
Cytogenetic Map5E3UniSTS
Cytogenetic Map15D3UniSTS
Cytogenetic Map2H2UniSTS
Cytogenetic Map7D3UniSTS
Cytogenetic Map2A1UniSTS
Cytogenetic Map14C1UniSTS
Cytogenetic Map14E5UniSTS
Cytogenetic Map10CUniSTS
Cytogenetic Map18B2UniSTS
Cytogenetic Map2F1UniSTS
Cytogenetic Map10D3UniSTS
Cytogenetic Map17A2UniSTS
Cytogenetic Map2C3UniSTS
Cytogenetic Map1C3UniSTS
Cytogenetic Map17B2UniSTS
Cytogenetic Map5B2UniSTS
Cytogenetic Map5G1UniSTS
Cytogenetic Map4C6UniSTS
Cytogenetic Map13C3UniSTS
Cytogenetic Map2E1UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
Cytogenetic Map19C3UniSTS
Cytogenetic Map7E3UniSTS
Cytogenetic Map13C1UniSTS
Cytogenetic Map9E3.1UniSTS
Cytogenetic Map15E3UniSTS
Cytogenetic Map6B1UniSTS
Cytogenetic MapXE3UniSTS
Cytogenetic Map4C4UniSTS
Cytogenetic Map3E3UniSTS
Cytogenetic Map11A4UniSTS
Cytogenetic Map4C5UniSTS
Cytogenetic Map18B3UniSTS
Cytogenetic Map9A2UniSTS
Cytogenetic Map7E1UniSTS
Cytogenetic Map5D-E1UniSTS
Cytogenetic Map5B3UniSTS
Cytogenetic Map13A2-A3UniSTS
Cytogenetic Map5A2UniSTS
Cytogenetic Map4B3UniSTS
Cytogenetic Map1E4UniSTS
Cytogenetic Map17E4UniSTS
Cytogenetic Map1G2UniSTS
Cytogenetic Map15B3.1UniSTS
Cytogenetic Map12EUniSTS
Cytogenetic MapXA5UniSTS
Cytogenetic Map6A3.3UniSTS
Cytogenetic Map6G3UniSTS
Cytogenetic Map6F2UniSTS
Cytogenetic Map5C1UniSTS
Cytogenetic Map4D2.1UniSTS
Cytogenetic Map4A5UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map1E3-E4UniSTS
Cytogenetic Map9F1-F3UniSTS
Cytogenetic Map1C1.1UniSTS
Cytogenetic Map14D2UniSTS
Cytogenetic Map12A2UniSTS
Cytogenetic Map17A3-BUniSTS
Cytogenetic Map7F5UniSTS
Cytogenetic Map14A3UniSTS
Cytogenetic Map5G1.1UniSTS
Cytogenetic MapXF2-F4UniSTS
Cytogenetic Map7D2UniSTS
Cytogenetic Map2F3UniSTS
Cytogenetic Map10A3UniSTS
Cytogenetic MapXA7.3UniSTS
Cytogenetic Map9F1-F2UniSTS
Cytogenetic Map13A3.2UniSTS
Cytogenetic Map10A2UniSTS
Cytogenetic Map1C1UniSTS
Cytogenetic Map1A1UniSTS
Cytogenetic Map12D3UniSTS
Cytogenetic Map1A3-A5UniSTS
Cytogenetic Map2A2UniSTS
Cytogenetic Map3A1UniSTS
Cytogenetic MapXA3.3UniSTS
Cytogenetic Map16A-B1UniSTS
Cytogenetic Map1D2.3UniSTS
Cytogenetic Map6B2.3UniSTS
Cytogenetic Map2G3UniSTS
Cytogenetic MapXA2-A3.1UniSTS
Cytogenetic Map9A5.3UniSTS
Cytogenetic Map14A2-BUniSTS
Cytogenetic Map8E1-E2UniSTS
Cytogenetic Map8A3UniSTS
Cytogenetic Map1G3-H1UniSTS
Cytogenetic Map8B3-C1UniSTS
Cytogenetic Map19C1UniSTS
Cytogenetic Map8C5UniSTS
Cytogenetic Map8A4UniSTS
Cytogenetic Map15F3UniSTS
Cytogenetic Map14E4UniSTS
Cytogenetic Map4D2.2UniSTS
Cytogenetic MapXF5UniSTS
cM Map1040.0UniSTS
Whitehead Genetic1033.9UniSTS
Hus1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38118,996,649 - 8,996,870UniSTSGRCm38
MGSCv37118,896,652 - 8,896,873UniSTSGRCm37
Celera119,429,465 - 9,429,686UniSTS
Cytogenetic Map11A1UniSTS
cM Map113.0UniSTS
AF076845  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38118,996,746 - 8,996,840UniSTSGRCm38
MGSCv37118,896,749 - 8,896,843UniSTSGRCm37
Celera119,429,562 - 9,429,656UniSTS
Cytogenetic Map11A1UniSTS
Whitehead/MRC_RH1143.77UniSTS






1 to 19 of 19 rows
RefSeq Transcripts NM_001303532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001303610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001432036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_130178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006514531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004936781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF076845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK046152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK051839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK135922 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL669837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB611267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC047460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC061249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DV650764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y16894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 19 of 19 rows

Ensembl Acc Id: ENSMUST00000020683   ⟹   ENSMUSP00000020683
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl118,943,137 - 8,961,191 (-)Ensembl
GRCm38.p6 Ensembl118,993,137 - 9,011,191 (-)Ensembl
Ensembl Acc Id: ENSMUST00000127578
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl118,955,989 - 8,961,128 (-)Ensembl
GRCm38.p6 Ensembl119,005,989 - 9,011,128 (-)Ensembl
Ensembl Acc Id: ENSMUST00000129115   ⟹   ENSMUSP00000114339
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl118,943,137 - 8,961,160 (-)Ensembl
GRCm38.p6 Ensembl118,993,137 - 9,011,160 (-)Ensembl
Ensembl Acc Id: ENSMUST00000139877
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl118,947,340 - 8,961,164 (-)Ensembl
GRCm38.p6 Ensembl118,997,340 - 9,011,164 (-)Ensembl
Ensembl Acc Id: ENSMUST00000146002
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl118,948,739 - 8,960,678 (-)Ensembl
GRCm38.p6 Ensembl118,998,739 - 9,010,678 (-)Ensembl
Ensembl Acc Id: ENSMUST00000152890
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl118,945,356 - 8,961,128 (-)Ensembl
GRCm38.p6 Ensembl118,995,356 - 9,011,128 (-)Ensembl
RefSeq Acc Id: NM_001303532   ⟹   NP_001290461
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39118,943,137 - 8,961,191 (-)NCBI
GRCm38118,993,137 - 9,011,191 (-)NCBI
Celera119,425,953 - 9,444,026 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001303610   ⟹   NP_001290539
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39118,943,137 - 8,961,191 (-)NCBI
GRCm38118,993,137 - 9,011,191 (-)NCBI
Celera119,425,953 - 9,444,026 (-)NCBI
Sequence:
RefSeq Acc Id: NM_008316   ⟹   NP_032342
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39118,943,137 - 8,961,191 (-)NCBI
GRCm38118,993,137 - 9,011,191 (-)NCBI
MGSCv37118,893,145 - 8,911,140 (-)RGD
Celera119,425,953 - 9,444,026 (-)NCBI
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_130178
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39118,943,137 - 8,961,191 (-)NCBI
GRCm38118,993,137 - 9,011,191 (-)NCBI
Celera119,425,953 - 9,444,026 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006514531   ⟹   XP_006514594
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39118,946,939 - 8,961,240 (-)NCBI
GRCm38118,996,939 - 9,011,236 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004936781
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39118,943,137 - 8,961,232 (-)NCBI
Sequence:
RefSeq Acc Id: NP_032342   ⟸   NM_008316
- Peptide Label: isoform 1
- UniProtKB: Q8BQY8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006514594   ⟸   XM_006514531
- Peptide Label: isoform X1
- UniProtKB: Q8BQY8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001290461   ⟸   NM_001303532
- Peptide Label: isoform 2
- UniProtKB: O70543 (UniProtKB/Swiss-Prot),   Q6P8H5 (UniProtKB/Swiss-Prot),   Q8BQY8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001290539   ⟸   NM_001303610
- Peptide Label: isoform 3
- Sequence:
Ensembl Acc Id: ENSMUSP00000020683   ⟸   ENSMUST00000020683

Name Modeler Protein Id AA Range Protein Structure
AF-Q8BQY8-F1-model_v2 AlphaFold Q8BQY8 1-280 view protein structure

RGD ID:6821086
Promoter ID:MM_KWN:6418
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000011503,   OTTMUST00000011504,   OTTMUST00000011505,   OTTMUST00000011506,   OTTMUST00000011507,   OTTMUST00000072684,   UC007HZP.1,   UC007HZR.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36118,910,849 - 8,911,349 (-)MPROMDB
RGD ID:8673944
Promoter ID:EPDNEW_M15001
Type:multiple initiation site
Name:Hus1_2
Description:Mus musculus HUS1 checkpoint clamp component , transcript variant4, non-coding RNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15002  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38119,005,616 - 9,005,676EPDNEW
RGD ID:8673942
Promoter ID:EPDNEW_M15002
Type:initiation region
Name:Hus1_1
Description:Mus musculus HUS1 checkpoint clamp component , transcript variant4, non-coding RNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15001  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38119,011,128 - 9,011,188EPDNEW


1 to 24 of 24 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000020413 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000020683 ENTREZGENE
  ENSMUST00000020683.10 UniProtKB/Swiss-Prot
  ENSMUST00000129115.2 UniProtKB/Swiss-Prot
  ENSMUST00000139877 ENTREZGENE
Gene3D-CATH 3.70.10.10 UniProtKB/Swiss-Prot
InterPro Cell_cycle_HUS1 UniProtKB/Swiss-Prot
  DNA_clamp_sf UniProtKB/Swiss-Prot
  Hus1/Mec3 UniProtKB/Swiss-Prot
KEGG Report mmu:15574 UniProtKB/Swiss-Prot
MGD MGI:1277962 ENTREZGENE
NCBI Gene 15574 ENTREZGENE
PANTHER CHECKPOINT PROTEIN HUS1 UniProtKB/Swiss-Prot
  MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1 UniProtKB/Swiss-Prot
Pfam Hus1 UniProtKB/Swiss-Prot
PhenoGen Hus1 PhenoGen
PIRSF Cell_cycle_HUS1 UniProtKB/Swiss-Prot
Superfamily-SCOP DNA clamp UniProtKB/Swiss-Prot
UniProt HUS1_MOUSE UniProtKB/Swiss-Prot
  O70543 ENTREZGENE
  Q6P8H5 ENTREZGENE
  Q8BQY8 ENTREZGENE
UniProt Secondary O70543 UniProtKB/Swiss-Prot
  Q6P8H5 UniProtKB/Swiss-Prot
1 to 24 of 24 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-29 Hus1  HUS1 checkpoint clamp component    Hus1 homolog (S. pombe)  Symbol and/or name change 5135510 APPROVED