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Gene: Efhc1 (EF-hand domain (C-terminal) containing 1) Mus musculus

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Symbol:

Efhc1

Name:

EF-hand domain (C-terminal) containing 1

RGD ID:

1317535

MGI Page

MGI

Description:

Predicted to enable alpha-tubulin binding activity. Involved in flagellated sperm motility. Located in axoneme and neuronal cell body. Is active in axonemal A tubule inner sheath and sperm flagellum. Is expressed in several structures, including brain; epithelium; future hindbrain roof plate; spinal cord ventricular layer; and spleen. Used to study juvenile myoclonic epilepsy. Human ortholog(s) of this gene implicated in juvenile absence epilepsy 1 and juvenile myoclonic epilepsy. Orthologous to human EFHC1 (EF-hand domain containing 1).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

1700029F22Rik; EF-hand domain-containing protein 1; mRib72; mRib72-1; myoc; myoclonin-1; myoclonin1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	EFHC1 (EF-hand domain containing 1)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Rattus norvegicus (Norway rat):	Efhc1 (EF-hand domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Efhc1 (EF-hand domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	EFHC1 (EF-hand domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	EFHC1 (EF-hand domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Efhc1 (EF-hand domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	EFHC1 (EF-hand domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	EFHC1 (EF-hand domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Efhc1 (EF-hand domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	EFHC1 (EF-hand domain containing 1)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Rattus norvegicus (Norway rat):	Efhc1 (EF-hand domain containing 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	efhc1 (EF-hand domain (C-terminal) containing 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Caenorhabditis elegans (roundworm):	efhc-1	Alliance	DIOPT (InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	efhc1	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	21,021,776 - 21,061,065 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	21,021,850 - 21,061,065 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	20,951,553 - 20,990,841 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	20,951,626 - 20,990,841 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	20,941,707 - 20,980,922 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	20,936,839 - 20,975,992 (+)	NCBI		MGSCv36	mm8
Celera	1	20,826,576 - 20,865,461 (+)	NCBI		Celera
Cytogenetic Map	1	A4	NCBI
cM Map	1	6.5	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Efhc1	Mouse	absence epilepsy		ISO	RGD:1317534	8554872	ClinVar Annotator: match by term: Absence epilepsy \| ClinVar Annotator: match by term: Absence seizure	ClinVar	PMID:12439895\|PMID:15258581\|PMID:16839746\|PMID:17054699\|PMID:17159113\|PMID:17576681\|PMID:17634063\|PMID:18414213\|PMID:18823326\|PMID:20981092\|PMID:22226147\|PMID:22690745\|PMID:22727576\|PMID:22926142\|PMID:23527921\|PMID:24033266\|PMID:24965021\|PMID:25108116\|PMID:25489633\|PMID:25625532\|PMID:25741868\|PMID:26467025\|PMID:27467453\|PMID:28166811\|PMID:28370826\|PMID:28492532\|PMID:29750216\|PMID:31875159\|PMID:34426522\|PMID:34645491\|PMID:8737649\|PMID:9536098
Efhc1	Mouse	absence epilepsy		ISO	RGD:1317534	8554872	ClinVar Annotator: match by term: Absence epilepsy \| ClinVar Annotator: match by term: Absence seizure more ...	ClinVar	PMID:12439895\|PMID:15258581\|PMID:16839746\|PMID:17054699\|PMID:17159113\|PMID:17576681\|PMID:17634063\|PMID:18414213\|PMID:18823326\|PMID:20981092\|PMID:22226147\|PMID:22690745\|PMID:22727576\|PMID:22926142\|PMID:23527921\|PMID:24033266\|PMID:24965021\|PMID:25108116\|PMID:25489633\|PMID:25625532\|PMID:25741868\|PMID:26132555\|PMID:26467025\|PMID:27467453\|PMID:28166811\|PMID:28370826\|PMID:28492532\|PMID:29750216\|PMID:31875159\|PMID:34426522\|PMID:8737649\|PMID:9536098
Efhc1	Mouse	epilepsy		ISO	RGD:1317534	8554872	ClinVar Annotator: match by term: Seizure	ClinVar	PMID:25741868\|PMID:28492532
Efhc1	Mouse	Idiopathic Generalized Epilepsy 7		ISO	RGD:1317534	8554872	ClinVar Annotator: match by term: Epilepsy, idiopathic generalized, susceptibility to, 7	ClinVar	PMID:25741868\|PMID:28492532
Efhc1	Mouse	juvenile absence epilepsy 1		ISO	RGD:1317534	8554872	ClinVar Annotator: match by term: Epilepsy, juvenile absence, susceptibility to, 1	ClinVar	PMID:25741868\|PMID:28492532
Efhc1	Mouse	juvenile myoclonic epilepsy		ISO	RGD:1317534	8554872	ClinVar Annotator: match by term: EJM1 \| ClinVar Annotator: match by term: Janz syndrome \| more ...	ClinVar	PMID:12439895\|PMID:15258581\|PMID:16199547\|PMID:16839746\|PMID:17054699\|PMID:17159113\|PMID:17634063\|PMID:18414213\|PMID:18505993\|PMID:18823326\|PMID:20981092\|PMID:22226147\|PMID:22690745\|PMID:22727576\|PMID:22926142\|PMID:23527921\|PMID:24965021\|PMID:25108116\|PMID:25326635\|PMID:25489633\|PMID:25625532\|PMID:25741868\|PMID:26467025\|PMID:27467453\|PMID:28370826\|PMID:28492532\|PMID:29750216\|PMID:34426522\|PMID:34645491\|PMID:8737649

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Efhc1	Mouse	childhood absence epilepsy		ISO	RGD:1317534	11554173	CTD Direct Evidence: marker/mechanism	CTD
Efhc1	Mouse	juvenile myoclonic epilepsy		ISO	RGD:1317534	11554173	CTD Direct Evidence: marker/mechanism	CTD

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Efhc1	Mouse	juvenile myoclonic epilepsy		IAGP		13592920	OMIM:254770 \| OMIM:608816 \| OMIM:611364 \| OMIM:614280	MouseDO

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Efhc1	Mouse	juvenile absence epilepsy 1	susceptibility	ISO	RGD:1317534	7240710		OMIM
Efhc1	Mouse	juvenile myoclonic epilepsy	susceptibility	ISO	RGD:1317534	7240710		OMIM

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Efhc1	Mouse	(-)-demecolcine	increases expression	ISO	RGD:1317534	6480464	Demecolcine results in increased expression of EFHC1 mRNA	CTD	PMID:23649840
Efhc1	Mouse	(-)-epigallocatechin 3-gallate	multiple interactions	ISO	RGD:1317534	6480464	[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of EFHC1 mRNA	CTD	PMID:22079256
Efhc1	Mouse	17beta-estradiol	decreases expression	EXP		6480464	Estradiol results in decreased expression of EFHC1 mRNA	CTD	PMID:39298647
Efhc1	Mouse	2,3,7,8-tetrachlorodibenzodioxine	increases expression	ISO	RGD:1587365	6480464	Tetrachlorodibenzodioxin results in increased expression of EFHC1 mRNA	CTD	PMID:33387578
Efhc1	Mouse	4,4'-sulfonyldiphenol	increases expression	EXP		6480464	bisphenol S results in increased expression of EFHC1 mRNA	CTD	PMID:30951980
Efhc1	Mouse	6-propyl-2-thiouracil	decreases expression	ISO	RGD:1587365	6480464	Propylthiouracil results in decreased expression of EFHC1 mRNA	CTD	PMID:25825206
Efhc1	Mouse	acrolein	multiple interactions	ISO	RGD:1317534	6480464	[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] affects the expression of EFHC1 more ...	CTD	PMID:32699268
Efhc1	Mouse	aflatoxin B1	increases expression	ISO	RGD:1587365	6480464	Aflatoxin B1 results in increased expression of EFHC1 mRNA	CTD	PMID:23630614
Efhc1	Mouse	aldehydo-D-glucose	multiple interactions	EXP		6480464	[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose more ...	CTD	PMID:37567420
Efhc1	Mouse	alpha-pinene	multiple interactions	ISO	RGD:1317534	6480464	[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] affects the expression of EFHC1 more ...	CTD	PMID:32699268
Efhc1	Mouse	amphetamine	increases expression	ISO	RGD:1587365	6480464	Amphetamine results in increased expression of EFHC1 mRNA	CTD	PMID:30779732
Efhc1	Mouse	arsane	multiple interactions	ISO	RGD:1317534	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:39836092
Efhc1	Mouse	arsenic atom	multiple interactions	ISO	RGD:1317534	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:39836092
Efhc1	Mouse	benzo[a]pyrene	increases expression	EXP		6480464	Benzo(a)pyrene results in increased expression of EFHC1 mRNA	CTD	PMID:27195522
Efhc1	Mouse	benzo[a]pyrene	increases methylation	ISO	RGD:1317534	6480464	Benzo(a)pyrene results in increased methylation of EFHC1 promoter	CTD	PMID:27901495
Efhc1	Mouse	benzo[a]pyrene	increases methylation	EXP		6480464	Benzo(a)pyrene results in increased methylation of EFHC1 exon; Benzo(a)pyrene results in increased methylation of EFHC1 more ...	CTD	PMID:27901495
Efhc1	Mouse	benzo[a]pyrene diol epoxide I	decreases expression	ISO	RGD:1317534	6480464	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of EFHC1 mRNA	CTD	PMID:20018196
Efhc1	Mouse	beta-lapachone	decreases expression	ISO	RGD:1317534	6480464	beta-lapachone results in decreased expression of EFHC1 mRNA	CTD	PMID:38218311
Efhc1	Mouse	bis(2-ethylhexyl) phthalate	decreases expression	ISO	RGD:1317534	6480464	Diethylhexyl Phthalate results in decreased expression of EFHC1 mRNA	CTD	PMID:31163220
Efhc1	Mouse	bis(2-ethylhexyl) phthalate	increases expression	EXP		6480464	Diethylhexyl Phthalate results in increased expression of EFHC1 mRNA	CTD	PMID:34319233
Efhc1	Mouse	bisphenol A	decreases expression	ISO	RGD:1317534	6480464	bisphenol A results in decreased expression of EFHC1 mRNA	CTD	PMID:22576693
Efhc1	Mouse	bisphenol A	multiple interactions	ISO	RGD:1317534	6480464	[bisphenol A co-treated with Fulvestrant] affects the methylation of EFHC1 gene	CTD	PMID:31601247
Efhc1	Mouse	bisphenol A	decreases methylation	ISO	RGD:1317534	6480464	bisphenol A results in decreased methylation of EFHC1 gene	CTD	PMID:31601247
Efhc1	Mouse	bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of EFHC1 mRNA	CTD	PMID:30951980
Efhc1	Mouse	bisphenol A	decreases expression	ISO	RGD:1587365	6480464	bisphenol A results in decreased expression of EFHC1 mRNA	CTD	PMID:25181051\|PMID:29097150
Efhc1	Mouse	bisphenol A	increases methylation	ISO	RGD:1317534	6480464	bisphenol A results in increased methylation of EFHC1 gene	CTD	PMID:22576693
Efhc1	Mouse	bisphenol F	increases expression	EXP		6480464	bisphenol F results in increased expression of EFHC1 mRNA	CTD	PMID:30951980
Efhc1	Mouse	cadmium dichloride	increases expression	ISO	RGD:1317534	6480464	Cadmium Chloride results in increased expression of EFHC1 mRNA	CTD	PMID:38382870
Efhc1	Mouse	carbon nanotube	decreases expression	EXP		6480464	Nanotubes, Carbon analog results in decreased expression of EFHC1 mRNA; Nanotubes, Carbon results in decreased more ...	CTD	PMID:25554681
Efhc1	Mouse	CGP 52608	multiple interactions	ISO	RGD:1317534	6480464	CGP 52608 promotes the reaction [RORA protein binds to EFHC1 gene]	CTD	PMID:28238834
Efhc1	Mouse	chloroprene	increases expression	EXP		6480464	Chloroprene results in increased expression of EFHC1 mRNA	CTD	PMID:23125180
Efhc1	Mouse	choline	multiple interactions	EXP		6480464	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ...	CTD	PMID:20938992
Efhc1	Mouse	copper(II) sulfate	decreases expression	ISO	RGD:1317534	6480464	Copper Sulfate results in decreased expression of EFHC1 mRNA	CTD	PMID:19549813
Efhc1	Mouse	Cuprizon	increases expression	ISO	RGD:1587365	6480464	Cuprizone results in increased expression of EFHC1 mRNA	CTD	PMID:26577399\|PMID:27523638
Efhc1	Mouse	cyclosporin A	increases expression	ISO	RGD:1317534	6480464	Cyclosporine results in increased expression of EFHC1 mRNA	CTD	PMID:20106945
Efhc1	Mouse	D-glucose	multiple interactions	EXP		6480464	[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose more ...	CTD	PMID:37567420
Efhc1	Mouse	Dibutyl phosphate	affects expression	ISO	RGD:1317534	6480464	di-n-butylphosphoric acid affects the expression of EFHC1 mRNA	CTD	PMID:37042841
Efhc1	Mouse	dorsomorphin	multiple interactions	ISO	RGD:1317534	6480464	[NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Efhc1	Mouse	doxorubicin	decreases expression	ISO	RGD:1317534	6480464	Doxorubicin results in decreased expression of EFHC1 mRNA	CTD	PMID:29803840
Efhc1	Mouse	elemental selenium	decreases expression	ISO	RGD:1317534	6480464	Selenium results in decreased expression of EFHC1 mRNA	CTD	PMID:19244175
Efhc1	Mouse	ethyl methanesulfonate	increases expression	ISO	RGD:1317534	6480464	Ethyl Methanesulfonate results in increased expression of EFHC1 mRNA	CTD	PMID:23649840
Efhc1	Mouse	folic acid	multiple interactions	EXP		6480464	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ...	CTD	PMID:20938992
Efhc1	Mouse	formaldehyde	increases expression	ISO	RGD:1317534	6480464	Formaldehyde results in increased expression of EFHC1 mRNA	CTD	PMID:23649840
Efhc1	Mouse	fructose	multiple interactions	EXP		6480464	[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose more ...	CTD	PMID:37567420
Efhc1	Mouse	fulvestrant	increases methylation	ISO	RGD:1317534	6480464	Fulvestrant results in increased methylation of EFHC1 gene	CTD	PMID:31601247
Efhc1	Mouse	fulvestrant	multiple interactions	ISO	RGD:1317534	6480464	[bisphenol A co-treated with Fulvestrant] affects the methylation of EFHC1 gene	CTD	PMID:31601247
Efhc1	Mouse	furan	increases expression	ISO	RGD:1587365	6480464	furan results in increased expression of EFHC1 mRNA	CTD	PMID:27387713
Efhc1	Mouse	gentamycin	increases expression	ISO	RGD:1587365	6480464	Gentamicins results in increased expression of EFHC1 mRNA	CTD	PMID:33387578
Efhc1	Mouse	glucose	multiple interactions	EXP		6480464	[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose more ...	CTD	PMID:37567420
Efhc1	Mouse	glycidol	increases expression	ISO	RGD:1587365	6480464	glycidol results in increased expression of EFHC1 mRNA	CTD	PMID:24395379
Efhc1	Mouse	glyphosate	multiple interactions	EXP		6480464	[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose more ...	CTD	PMID:37567420
Efhc1	Mouse	L-methionine	multiple interactions	EXP		6480464	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ...	CTD	PMID:20938992
Efhc1	Mouse	manganese atom	multiple interactions	ISO	RGD:1317534	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:39836092
Efhc1	Mouse	manganese(0)	multiple interactions	ISO	RGD:1317534	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:39836092
Efhc1	Mouse	manganese(II) chloride	multiple interactions	ISO	RGD:1317534	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:39836092
Efhc1	Mouse	methyl methanesulfonate	increases expression	ISO	RGD:1317534	6480464	Methyl Methanesulfonate results in increased expression of EFHC1 mRNA	CTD	PMID:23649840
Efhc1	Mouse	methylmercury chloride	decreases expression	ISO	RGD:1317534	6480464	methylmercuric chloride results in decreased expression of EFHC1 mRNA	CTD	PMID:28001369
Efhc1	Mouse	nickel atom	decreases expression	ISO	RGD:1317534	6480464	Nickel results in decreased expression of EFHC1 mRNA	CTD	PMID:24768652\|PMID:25583101
Efhc1	Mouse	nickel sulfate	increases expression	ISO	RGD:1317534	6480464	nickel sulfate results in increased expression of EFHC1 mRNA	CTD	PMID:22714537
Efhc1	Mouse	okadaic acid	decreases expression	ISO	RGD:1317534	6480464	Okadaic Acid results in decreased expression of EFHC1 mRNA	CTD	PMID:38832940
Efhc1	Mouse	ozone	multiple interactions	ISO	RGD:1317534	6480464	[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] affects the expression of EFHC1 more ...	CTD	PMID:32699268
Efhc1	Mouse	ozone	multiple interactions	EXP		6480464	[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased more ...	CTD	PMID:34911549
Efhc1	Mouse	paracetamol	decreases expression	ISO	RGD:1317534	6480464	Acetaminophen results in decreased expression of EFHC1 mRNA	CTD	PMID:21420995
Efhc1	Mouse	pirinixic acid	multiple interactions	EXP		6480464	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ...	CTD	PMID:19710929
Efhc1	Mouse	potassium chromate	decreases expression	ISO	RGD:1317534	6480464	potassium chromate(VI) results in decreased expression of EFHC1 mRNA	CTD	PMID:22079256
Efhc1	Mouse	potassium chromate	multiple interactions	ISO	RGD:1317534	6480464	[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of EFHC1 mRNA	CTD	PMID:22079256
Efhc1	Mouse	rotenone	decreases expression	ISO	RGD:1317534	6480464	Rotenone results in decreased expression of EFHC1 mRNA	CTD	PMID:29955902
Efhc1	Mouse	SB 431542	multiple interactions	ISO	RGD:1317534	6480464	[NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Efhc1	Mouse	selenium atom	decreases expression	ISO	RGD:1317534	6480464	Selenium results in decreased expression of EFHC1 mRNA	CTD	PMID:19244175
Efhc1	Mouse	silicon dioxide	decreases expression	ISO	RGD:1317534	6480464	Silicon Dioxide results in decreased expression of EFHC1 mRNA	CTD	PMID:25351596
Efhc1	Mouse	sodium arsenite	decreases expression	ISO	RGD:1317534	6480464	sodium arsenite results in decreased expression of EFHC1 mRNA	CTD	PMID:38568856
Efhc1	Mouse	sodium arsenite	multiple interactions	ISO	RGD:1317534	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:39836092
Efhc1	Mouse	sodium arsenite	increases expression	EXP		6480464	sodium arsenite results in increased expression of EFHC1 mRNA	CTD	PMID:37682722
Efhc1	Mouse	sodium fluoride	increases expression	EXP		6480464	Sodium Fluoride results in increased expression of EFHC1 protein	CTD	PMID:28918527
Efhc1	Mouse	sunitinib	increases expression	ISO	RGD:1317534	6480464	Sunitinib results in increased expression of EFHC1 mRNA	CTD	PMID:31533062
Efhc1	Mouse	titanium dioxide	affects expression	EXP		6480464	titanium dioxide affects the expression of EFHC1 mRNA	CTD	PMID:23557971
Efhc1	Mouse	titanium dioxide	decreases methylation	EXP		6480464	titanium dioxide results in decreased methylation of EFHC1 gene	CTD	PMID:35295148
Efhc1	Mouse	trichloroethene	increases expression	ISO	RGD:1587365	6480464	Trichloroethylene results in increased expression of EFHC1 mRNA	CTD	PMID:33387578
Efhc1	Mouse	trichostatin A	decreases expression	ISO	RGD:1317534	6480464	trichostatin A results in decreased expression of EFHC1 mRNA	CTD	PMID:24935251\|PMID:26272509
Efhc1	Mouse	trichostatin A	multiple interactions	ISO	RGD:1317534	6480464	[NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Efhc1	Mouse	triptonide	increases expression	EXP		6480464	triptonide results in increased expression of EFHC1 mRNA	CTD	PMID:33045310
Efhc1	Mouse	tunicamycin	increases expression	ISO	RGD:1317534	6480464	Tunicamycin results in increased expression of EFHC1 mRNA	CTD	PMID:22378314
Efhc1	Mouse	valproic acid	decreases expression	ISO	RGD:1317534	6480464	Valproic Acid results in decreased expression of EFHC1 mRNA	CTD	PMID:24383497
Efhc1	Mouse	valproic acid	increases expression	ISO	RGD:1317534	6480464	Valproic Acid results in increased expression of EFHC1 mRNA	CTD	PMID:23179753\|PMID:28001369
Efhc1	Mouse	valproic acid	affects expression	ISO	RGD:1317534	6480464	Valproic Acid affects the expression of EFHC1 mRNA	CTD	PMID:25979313
Efhc1	Mouse	vitamin E	decreases expression	ISO	RGD:1317534	6480464	Vitamin E results in decreased expression of EFHC1 mRNA	CTD	PMID:19244175

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Efhc1	Mouse	cerebral cortex cell migration	involved_in	ISO	UniProtKB:Q5JVL4	2290270		GO_Central	GO_REF:0000119
Efhc1	Mouse	cilium-dependent cell motility	involved_in	IBA	PANTHER:PTN000250050\|UniProtKB:Q8LKK4\|MGI:1919127	2290270		GO_Central	GO_REF:0000033
Efhc1	Mouse	flagellated sperm motility	involved_in	IDA		2290270	PMID:37295417, PMID:37865089, PMID:37989994	UniProt	PMID:37295417\|PMID:37865089\|PMID:37989994
Efhc1	Mouse	intracellular calcium ion homeostasis	involved_in	NAS		2290270	PMID:15258581	UniProt	PMID:15258581
Efhc1	Mouse	mitotic cytokinesis	involved_in	ISO	UniProtKB:Q5JVL4	2290270		GO_Central	GO_REF:0000119
Efhc1	Mouse	mitotic cytokinesis	involved_in	IBA	PANTHER:PTN000250050\|UniProtKB:Q5JVL4	2290270		GO_Central	GO_REF:0000033
Efhc1	Mouse	mitotic cytokinesis	involved_in	ISS	UniProtKB:Q5JVL4	2290270		UniProt	GO_REF:0000024
Efhc1	Mouse	mitotic spindle organization	involved_in	ISS	UniProtKB:Q5JVL4	2290270		UniProt	GO_REF:0000024
Efhc1	Mouse	mitotic spindle organization	involved_in	IBA	PANTHER:PTN000250050\|UniProtKB:Q5JVL4	2290270		GO_Central	GO_REF:0000033
Efhc1	Mouse	mitotic spindle organization	involved_in	ISO	UniProtKB:Q5JVL4	2290270		GO_Central	GO_REF:0000119
Efhc1	Mouse	positive regulation of apoptotic process	involved_in	NAS		2290270	PMID:15258581	UniProt	PMID:15258581
Efhc1	Mouse	regulation of cell division	involved_in	ISS	UniProtKB:Q5JVL4	2290270		UniProt	GO_REF:0000024
Efhc1	Mouse	regulation of cell division	involved_in	ISO	UniProtKB:Q5JVL4	2290270		GO_Central	GO_REF:0000119

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Efhc1	Mouse	axonemal A tubule inner sheath	is_active_in	IDA		2290270	PMID:37295417, PMID:37865089, PMID:37989994	UniProt	PMID:37295417\|PMID:37865089\|PMID:37989994
Efhc1	Mouse	axonemal microtubule	located_in	ISS	UniProtKB:E1BKH1	2290270		UniProt	GO_REF:0000024
Efhc1	Mouse	axonemal microtubule	located_in	ISO	UniProtKB:Q5JVL4	2290270		GO_Central	GO_REF:0000119
Efhc1	Mouse	axoneme	located_in	IDA		2290270	PMID:15670853	UniProt	PMID:15670853
Efhc1	Mouse	axoneme	is_active_in	IBA	PANTHER:PTN000250050\|MGI:1919127\|UniProtKB:E1BKH1\|UniProtKB:Q5JVL4\|UniProtKB:Q8LKK4	2290270		GO_Central	GO_REF:0000033
Efhc1	Mouse	centrosome	located_in	IEA	UniProtKB-SubCell:SL-0048	2290270		UniProt	GO_REF:0000044
Efhc1	Mouse	centrosome	located_in	ISO	UniProtKB:Q5JVL4	2290270		GO_Central	GO_REF:0000119
Efhc1	Mouse	cilium	located_in	IDA		2290270	PMID:15670853	MGI	PMID:15670853
Efhc1	Mouse	mitotic spindle	located_in	ISS	UniProtKB:Q5JVL4	2290270		UniProt	GO_REF:0000024
Efhc1	Mouse	mitotic spindle	is_active_in	IBA	PANTHER:PTN000250050\|UniProtKB:Q5JVL4	2290270		GO_Central	GO_REF:0000033
Efhc1	Mouse	mitotic spindle	located_in	ISO	UniProtKB:Q5JVL4	2290270		GO_Central	GO_REF:0000119
Efhc1	Mouse	neuronal cell body	located_in	IDA		2290270	PMID:15258581	UniProt	PMID:15258581
Efhc1	Mouse	sperm flagellum	is_active_in	IDA		2290270	PMID:37295417, PMID:37865089, PMID:37989994	UniProt	PMID:37295417\|PMID:37865089\|PMID:37989994
Efhc1	Mouse	spindle pole	located_in	ISS	UniProtKB:Q5JVL4	2290270		UniProt	GO_REF:0000024
Efhc1	Mouse	spindle pole	located_in	ISO	UniProtKB:Q5JVL4	2290270		GO_Central	GO_REF:0000119

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Efhc1	Mouse	alpha-tubulin binding	enables	ISS	UniProtKB:Q5JVL4	2290270		UniProt	GO_REF:0000024
Efhc1	Mouse	alpha-tubulin binding	enables	IBA	PANTHER:PTN000250050\|UniProtKB:Q5JVL4	2290270		GO_Central	GO_REF:0000033
Efhc1	Mouse	alpha-tubulin binding	enables	ISO	UniProtKB:Q5JVL4	2290270		GO_Central	GO_REF:0000119
Efhc1	Mouse	calcium ion binding	enables	IEA	InterPro:IPR002048	2290270		InterPro	GO_REF:0000002
Efhc1	Mouse	protein binding	enables	IPI	UniProtKB:Q61290	2290270	PMID:15258581	UniProt	PMID:15258581

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Efhc1	Mouse	abnormal brain ependyma motile cilium physiology		IAGP		5509061		MGI	PMID:19147686
Efhc1	Mouse	enlarged brain ventricles		IAGP		5509061		MGI	PMID:19147686
Efhc1	Mouse	increased susceptibility to pharmacologically induced seizures		IAGP		5509061		MGI	PMID:19147686
Efhc1	Mouse	myoclonus		IAGP		5509061		MGI	PMID:19147686
Efhc1	Mouse	small hippocampus		IAGP		5509061		MGI	PMID:19147686

#	Reference Title	Reference Citation
1.	Functional annotation of a full-length mouse cDNA collection.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2.	MGDs mouse GO annotations	MGD data from the GO Consortium
3.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
5.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:10349636	PMID:11042159	PMID:11076861	PMID:12040188	PMID:12095989	PMID:12477932	PMID:15258581	PMID:15670853	PMID:16141072	PMID:16141073	PMID:16572395	PMID:17971504
PMID:18164683	PMID:19147686	PMID:19191033	PMID:20015616	PMID:21267068	PMID:21677750	PMID:21873635	PMID:22226147	PMID:22926142	PMID:23213475	PMID:23756482	PMID:27467453
PMID:29539279	PMID:33328576	PMID:37295417	PMID:37865089	PMID:37989994

Efhc1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	21,021,776 - 21,061,065 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	21,021,850 - 21,061,065 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	20,951,553 - 20,990,841 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	20,951,626 - 20,990,841 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	20,941,707 - 20,980,922 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	20,936,839 - 20,975,992 (+)	NCBI		MGSCv36	mm8
Celera	1	20,826,576 - 20,865,461 (+)	NCBI		Celera
Cytogenetic Map	1	A4	NCBI
cM Map	1	6.5	NCBI

EFHC1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	52,420,342 - 52,497,198 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	52,362,123 - 52,529,886 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	52,285,140 - 52,361,996 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	52,392,953 - 52,468,542 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	52,393,070 - 52,465,177	NCBI
Celera	6	53,946,143 - 54,021,738 (+)	NCBI		Celera
Cytogenetic Map	6	p12.2	NCBI
HuRef	6	52,116,296 - 52,191,906 (+)	NCBI		HuRef
CHM1_1	6	52,287,207 - 52,362,796 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	52,259,137 - 52,336,010 (+)	NCBI		T2T-CHM13v2.0

Efhc1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	30,872,238 - 30,910,703 (+)	NCBI		GRCr8
mRatBN7.2	9	23,375,815 - 23,414,283 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	23,375,840 - 23,414,283 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	31,867,029 - 31,905,726 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	36,987,734 - 37,026,420 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	35,302,944 - 35,341,647 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	27,068,505 - 27,107,713 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	27,068,443 - 27,107,709 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	25,924,344 - 25,962,902 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	19,695,815 - 19,750,261 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	9	20,938,313 - 20,989,329 (+)	NCBI		Celera
Cytogenetic Map	9	q13	NCBI

Efhc1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955411	5,624,053 - 5,677,534 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955411	5,624,510 - 5,676,165 (-)	NCBI	ChiLan1.0	ChiLan1.0

EFHC1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	66,885,919 - 66,959,754 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	62,762,852 - 62,836,780 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	51,972,041 - 52,044,219 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	53,239,474 - 53,311,798 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	53,239,474 - 53,344,404 (+)	Ensembl	panpan1.1		panPan2

EFHC1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	20,068,287 - 20,131,621 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	20,067,881 - 20,131,619 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	19,965,029 - 20,028,364 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	20,567,201 - 20,630,760 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	20,566,156 - 20,630,767 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	20,072,968 - 20,136,374 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	20,176,667 - 20,240,190 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	20,315,041 - 20,378,596 (+)	NCBI		UU_Cfam_GSD_1.0

Efhc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	55,559,021 - 55,613,066 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936476	8,347,086 - 8,401,224 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936476	8,347,907 - 8,401,224 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

EFHC1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	46,239,230 - 46,348,667 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	46,244,915 - 46,320,261 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	133,966,766 - 134,041,685 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

EFHC1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	20,011,684 - 20,083,639 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	20,011,530 - 20,083,592 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	52,324,800 - 52,398,569 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Efhc1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624855	3,611,176 - 3,677,675 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624855	3,611,016 - 3,677,813 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Efhc1
2783 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	182
Count of miRNA genes:	174
Interacting mature miRNAs:	179
Transcripts:	ENSMUST00000038447, ENSMUST00000160782
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
11039528	Ccc3_m	colitis susceptibility in the Collaborative Cross 3 (mouse)					1	3680142	195051546	Mouse
1301011	Cplaq4_m	circadian period of locomotor activity 4 (mouse)			Not determined		1	9673442	43673601	Mouse
1301073	Orch5_m	autoimmune orchitis resistance 5 (mouse)			Not determined		1	19065351	53065454	Mouse
1301275	Sle10_m	systematic lupus erythematosus susceptibility 10 (mouse)			Not determined		1	2882194	36882352	Mouse
15092046	Wngrme1_m	week nine growth rate, maternal effect 1 (mouse)					1	3280142	37782236	Mouse
1301370	Adip1_m	adiposity 1 (mouse)			Not determined		1	2882194	36882352	Mouse
13824984	Twq5_m	testis weight QTL 5 (mouse)					1	3069992	184732197	Mouse
15092044	Wtgrme1_m	week ten growth rate, maternal effect 1 (mouse)					1	3280142	37782236	Mouse
1301240	Sluc15_m	susceptibility to lung cancer 15 (mouse)			Not determined		1	19065351	53065454	Mouse
1301471	Obq2_m	obesity QTL 2 (mouse)			Not determined		1	3941620	37941887	Mouse
14700685	Civq2_m	cerebral infarct volume QTL 2 (mouse)					1	11340482	45340482	Mouse
1301756	Pgia1_m	proteoglycan induced arthritis 1 (mouse)			Not determined		1	19065351	53065454	Mouse
1301891	Alcp25_m	alcohol preference locus 25 (mouse)			Not determined		1	1	25203185	Mouse
1300834	Cia20_m	collagen induced arthritis 20 (mouse)			Not determined		1	1	25203185	Mouse
15092055	Lgrme1_m	late growth rate, maternal effect 1 (mouse)					1	3280142	37782236	Mouse
4141646	Fecq3_m	fecundity QTL 3 (mouse)			Not determined		1	12916920	26517685	Mouse
12880407	V125Dq2_m	vitamin D active form serum level QTL 2 (mouse)					1	19339081	53339081	Mouse
15092050	Wsegrme1_m	week seven growth rate, maternal effect 1 (mouse)					1	3280142	37782236	Mouse
15092051	Wegrme1_m	week eight growth rate, maternal effect 1 (mouse)					1	3280142	37782236	Mouse
15092048	Wsigrme1_m	week six growth rate, maternal effect 1 (mouse)					1	3280142	37782236	Mouse
1301482	Morph1_m	morphine antinociception 1 (mouse)			Not determined		1	1	30367747	Mouse
10043970	Obq23_m	obesity QTL 23 (mouse)			Not determined		1	5012665	39012665	Mouse
10412226	Alpq4_m	alcohol preference QTL 4 (mouse)			Not determined		1	1	22976684	Mouse

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	NM_027974	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_003946579	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC156980	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK006489	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BY037196	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466536	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EU520262	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000038447 ⟹ ENSMUSP00000042343

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	1	21,021,912 - 21,061,065 (+)	Ensembl
GRCm38.p6 Ensembl	1	20,951,688 - 20,990,841 (+)	Ensembl

Ensembl Acc Id:

ENSMUST00000160782

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	1	21,021,850 - 21,025,751 (+)	Ensembl
GRCm38.p6 Ensembl	1	20,951,626 - 20,955,527 (+)	Ensembl

RefSeq Acc Id:

NM_027974 ⟹ NP_082250

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	1	21,021,850 - 21,061,065 (+)	NCBI
GRCm38	1	20,951,626 - 20,990,841 (+)	NCBI
MGSCv37	1	20,941,707 - 20,980,922 (+)	RGD
Celera	1	20,826,576 - 20,865,461 (+)	RGD
cM Map	1		ENTREZGENE

Sequence:

show sequence

TAGTGTGTTTGGCGTTACCAGGGAGTCTGGAGAGGCCCGCGAGTGCAGTTTGTTGCCAGGGTAACCCGAGCGGCAAAAGGCAACCGAGGTGGCAGCTGCAGGGCAGCGATGGGGACCAACCCGGTGCA
CGGCCTGCCCTTTCTCCCGGGCTCGTCCTTTACAGACTCCACGAAAACAGCATTCCACCGAAGCCAGACACTCAACTACAGGAACGGCTATGCAGTTGTCCGACGTCCCACCATGGGGATAGGTGGAG
ACCGGCTCCACTACAACCAGCTGTCTCAGGCCGAGCTGGATGAACTGGCCAATAAGGCACCCATCTTAACTTACGGGCCACTCAAGCAAGCCCCACTTGCAGAGTTTGTTCCTGCGCATGTGGCTTTT
GACAAAAAGGTGCTGAAATTTAGTGCCTACTTCCAAGAAGATGTTCCCATATCAATGGAGGAGCATTACCGAATCCGCCACGTGAACATTTACTACTACCTAGAAGATGACAGCATGTCTGTCATCGA
GCCCGTAGTGGAGAACTCTGGGATCCCACAAGGCAAGCTAATCAAACGCCAGCGGTTCACCAAGAATGATATGGGAGACCACTACCACTGGAAGGACCTCAACCGTGGAATCAACCTTACAGTGTACG
GCAAAACCTTCCGAATTGTTGACTGTGACCGATTCACTCAGGACTTTTTGGAAAGCCAAGGCATTGAATTAAATCCATCAGAGAAGATACCCCTGGATCCTTACACTCAACTCCGGAAAGAACCTGTG
CGCAAATATGTCACCCCGTCAGACTTTGACCAACTGAAACAGTTTCTCACCTTTGACAAACAGGTCCTTCGATTCTATGCCATCTGGGACGACACGGATAGCTTGTTCGGGGAATGTCGTCACTACAT
CATTCATTACTACCTCATGGATGACACCGTGGAGATCAGAGAGGTCCACGAACGGAACAACGGGAGAGACCCCTTCCCACTCCTCATGAACCGACAGCGTATGCCCAAAGTTTTGGTGGAGAATGCAA
AGAATTTCCCGAAGTGTGTGCTGGAAATCTCAGACCAAGAGGTGCTGGAGTGGTACACTGCCAAGGACTTCATTGTGGGGAAGCCGCTCACCATCCTGGGGAGGACCTTCTTCATCTACGACTGTGAC
CCATTCACACGACAGTTCTACAAAGACAAGTTTGGAATGCCTGACTTACCACCAGTTGATGTGACCAAGAAGGAGCCACCTCCAGTAAAACAGGAGTTGCCTCCTTATAATGGCTATGGACTAATTGA
AGACTCTGCTCAGAATTGTTTTGCTCTCATTCCTAAAGCTCCCAGAAAAGATGTCGTTAAAATGCTGATGAATGACAATAAGGTGCTCCGCTACCTGGCGGCCCTGGAATCCCCTATCCCAGAAGACA
AAGACCGTCGGTTTGTCTTCTCTTATTTTCTTGCCACGGATATGATCAGTATCTTTGAGCCACCTGTTCGAAATTCTGGGATCATCGGGGGCAAATTCCTGGGCAGGACTAAAGTTGTTAAATCATTC
TCTCCAGTTGACAACCCCATCTACTACTCACCAAGTGACTTCTTCATCGGTGCCGTGATTGAGGTGTTCGGCCATCGGTTCGTCATCCTCGATACAGATGAGTATGTTTTAAAATACATGGAGAGCAA
CGCTTCCCAGTATTCACCAGAAGCCCTGGCCTCAATTCAGAACCGGATCCAGAAGCCGGAGCTTCCCGCACCAGAACTGGAAAGCAAGCAAGCTACAGGAGAACCCATGGTGCAGGGTACAGAGGAAT
CCAAGGTGCAGGACTTGGATGCACTGATAGACCAAATCCATATGCACCTGAAATACAATTCATGCAAAGAAAACCTCCGTGAAACATTTCAAATGTATGACAAGGATGAATCGGGATATGTGGACAGA
GAGACGTTCTTTAAAATCTGTGAAACTCTTAATGTCCCGGTCGATGACTCGTTGATTAAGGAGTTGATCAGGCTGTGCACCCACGGAGAAGGCAGGATTAACTACTATAACTTTGTTCGAGCTTTCTC
GAACTGACCTGAACGAGAGAATGCGACAACATTTTTGACACTGAGCCGACATTGAGAAATCTACCACCCAAGCCTTTCAATAACTCCGGAAGTGGTATTTCTTTTCCCACTCTTCTATTTCACTATTA
CTCAAGTCTAAATTAATATTCAAAGAATTGAA

hide sequence

RefSeq Acc Id:

XR_003946579

Type:

NON-CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	1	21,021,776 - 21,061,065 (+)	NCBI
GRCm38	1	20,951,553 - 20,990,841 (+)	NCBI

Sequence:

show sequence

ACCTGGCCTCCGCCTCCCTTTCCCCGCCCCCTAACATCCTCCCCTCCTCCCCGCCGCTCCTCCC
CTCTCTCGACTAGTGTGTTTGGCGTTACCAGGGAGTCTGGAGAGGCCCGCGAGTGCAGTTTGTTGCCAGGGTAACCCGAGCGGCAAAAGGCAACCGAGGTGGCAGCTGCAGGGCAGCGATGGGGACCA
ACCCGGTGCACGGCCTGCCCTTTCTCCCGGGCTCGTCCTTTACAGACTCCACGAAAACAGCATTCCACCGAAGCCAGACACTCAACTACAGGAACGGCTATGCAGTTGTCCGACGTCCCACCATGGGG
ATAGGTGGAGACCGGCTCCACTACAACCAGCTGTCTCAGGCCGAGCTGGATGAACTGGCCAATAAGGCACCCATCTTAACTTACGGGCCACTCAAGCAAGCCCCACTTGCAGAGTTTGTTCCTGCGCA
TGTGGCTTTTGACAAAAAGGTGCTGAAATTTAGTGCCTACTTCCAAGAAGATGTTCCCATATCAATGGAGGAGCATTACCGAATCCGCCACGTGAACATTTACTACTACCTAGAAGATGACAGCATGT
CTGTCATCGAGCCCGTAGTGGAGAACTCTGGGATCCCACAAGGCAAGCTAATCAAACGCCAGCGGTTCACCAAGAATGATATGGGAGACCACTACCACTGGAAGGACCTCAACCGTGGAATCAACCTT
ACAGTGTACGGCAAAACCTTCCGAATTGTTGACTGTGACCGATTCACTCAGGACTTTTTGGAAAGCCAAGGCATTGAATTAAATCCATCAGAGAAGATACCCCTGGATCCTTACACTCAACTCCGGAA
AGAACCTGTGCGCAAATATGTCACCCCGTCAGACTTTGACCAACTGAAACAGTTTCTCACCTTTGACAAACAGGTCCTTCGATTCTATGCCATCTGGGACGACACGGATAGCTTGTTCGGGGAATGTC
GTCACTACATCATTCATTACTACCTCATGGATGACACCGTGGAGATCAGAGAGGTCCACGAACGGAACAACGGGAGAGACCCCTTCCCACTCCTCATGAACCGACAGCGTATGCCCAAAGTTTTGGTG
GAGAATGCAAAGAATTTCCCGAAGTGTGTGCTGGAAATCTCAGACCAAGAGGTGCTGGAGTGGTACACTGCCAAGGACTTCATTGTGGGGAAGCCGCTCACCATCCTGGGGAGGACCTTCTTCATCTA
CGACTGTGACCCATTCACACGACAGTTCTACAAAGACAAGTTTGGAATGCCTGACTTACCACCAGTTGATGTGACCAAGAAGGAGCCACCTCCAGTAAAACAGGAGTTGCCTCCTTATAATGGCTATG
GACTAATTGAAGACTCTGCTCAGAATTGTTTTGCTCTCATTCCTAAAGCTCCCAGAAAAGATGTCGTTAAAATGCTGATGAATGACAATAAGGTGCTCCGCTACCTGGCGGCCCTGGAATCCCCTATC
CCAGAAGACAAAGACCGTCGGTTTGTCTTCTCTTATTTTCTTGCCACGGATATGATCAGTATCTTTGAGCCACCTGTTCGAAATTCTGGGATCATCGGGGGCAAATTCCTGGGCAGGACTAAAGTTGT
TAAATCATTCTCTCCAGTTGACAACCCCATCTACTACTCACCAAGTGACTTCTTCATCGGTGCCGTGATTGAGGGGTTGGCATCATTTTGCTCCTGCTTGCATGAGAGAAACAAAGCTGAATTGAGTG
TGATGCTCCTCTCTCCTCAGTGTTCGGCCATCGGTTCGTCATCCTCGATACAGATGAGTATGTTTTAAAATACATGGAGAGCAACGCTTCCCAGTATTCACCAGAAGCCCTGGCCTCAATTCAGAACC
GGATCCAGAAGCCGGAGCTTCCCGCACCAGAACTGGAAAGCAAGCAAGCTACAGGAGAACCCATGGTGCAGGGTACAGAGGAATCCAAGGTGCAGGACTTGGATGCACTGATAGACCAAATCCATATG
CACCTGAAATACAATTCATGCAAAGAAAACCTCCGTGAAACATTTCAAATGTATGACAAGGATGAATCGGGATATGTGGACAGAGAGACGTTCTTTAAAATCTGTGAAACTCTTAATGTCCCGGTCGA
TGACTCGTTGATTAAGGAGTTGATCAGGCTGTGCACCCACGGAGAAGGCAGGATTAACTACTATAACTTTGTTCGAGCTTTCTCGAACTGACCTGAACGAGAGAATGCGACAACATTTTTGACACTGA
GCCGACATTGAGAAATCTACCACCCAAGCCTTTCAATAACTCCGGAAGTGGTATTTCTTTTCCCACTCTTCTATTTCACTATTACTCAAGTCTAAATTAATATTCAAAGAATTGAA

hide sequence


Protein RefSeqs	NP_082250	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	ACB20692	(Get FASTA)	NCBI Sequence Viewer
	BAB24614	(Get FASTA)	NCBI Sequence Viewer
	EDL14385	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000042343
GenBank Protein	Q9D9T8	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_082250 ⟸ NM_027974

- UniProtKB:

Q9D9T8 (UniProtKB/Swiss-Prot), B2CKC6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGTNPVHGLPFLPGSSFTDSTKTAFHRSQTLNYRNGYAVVRRPTMGIGGDRLHYNQLSQAELDELANKAPILTYGPLKQAPLAEFVPAHVAFDKKVLKFSAYFQEDVPISMEEHYRIRHVNIYYYLED
DSMSVIEPVVENSGIPQGKLIKRQRFTKNDMGDHYHWKDLNRGINLTVYGKTFRIVDCDRFTQDFLESQGIELNPSEKIPLDPYTQLRKEPVRKYVTPSDFDQLKQFLTFDKQVLRFYAIWDDTDSLF
GECRHYIIHYYLMDDTVEIREVHERNNGRDPFPLLMNRQRMPKVLVENAKNFPKCVLEISDQEVLEWYTAKDFIVGKPLTILGRTFFIYDCDPFTRQFYKDKFGMPDLPPVDVTKKEPPPVKQELPPY
NGYGLIEDSAQNCFALIPKAPRKDVVKMLMNDNKVLRYLAALESPIPEDKDRRFVFSYFLATDMISIFEPPVRNSGIIGGKFLGRTKVVKSFSPVDNPIYYSPSDFFIGAVIEVFGHRFVILDTDEYV
LKYMESNASQYSPEALASIQNRIQKPELPAPELESKQATGEPMVQGTEESKVQDLDALIDQIHMHLKYNSCKENLRETFQMYDKDESGYVDRETFFKICETLNVPVDDSLIKELIRLCTHGEGRINYY
NFVRAFSN

hide sequence

Ensembl Acc Id:

ENSMUSP00000042343 ⟸ ENSMUST00000038447

Protein Domains

DM10 EF-hand

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9D9T8-F1-model_v2	AlphaFold	Q9D9T8	1-648	view protein structure

RGD ID:

6817636

Promoter ID:

MM_KWN:236

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

NM_027974, OTTMUST00000074048

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	1	20,941,314 - 20,941,814 (+)	MPROMDB

RGD ID:

6873280

Promoter ID:

EPDNEW_M91

Type:

initiation region

Name:

Efhc1_1

Description:

Mus musculus EF-hand domain (C-terminal) containing 1 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	1	20,951,618 - 20,951,678	EPDNEW

Database	Acc Id	Source(s)
Ensembl Genes	ENSMUSG00000041809	Ensembl, ENTREZGENE
Ensembl Transcript	ENSMUST00000038447	ENTREZGENE
Gene3D-CATH	2.30.29.170	UniProtKB/Swiss-Prot
	EF-hand	UniProtKB/Swiss-Prot
InterPro	EF-hand-dom_pair	UniProtKB/Swiss-Prot
	EF_hand_dom	UniProtKB/Swiss-Prot
	EFHC1/EFHC2/EFHB	UniProtKB/Swiss-Prot
	Uncharacterised_DM10	UniProtKB/Swiss-Prot
KEGG Report	mmu:71877	UniProtKB/Swiss-Prot
MGD	MGI:1919127	ENTREZGENE
NCBI Gene	71877	ENTREZGENE
PANTHER	EF-HAND DOMAIN-CONTAINING PROTEIN 1	UniProtKB/Swiss-Prot
	PTHR12086	UniProtKB/Swiss-Prot
Pfam	DUF1126	UniProtKB/Swiss-Prot
	EF-hand_7	UniProtKB/Swiss-Prot
PhenoGen	Efhc1	PhenoGen
PROSITE	DM10	UniProtKB/Swiss-Prot
	EF_HAND_2	UniProtKB/Swiss-Prot
SMART	DM10	UniProtKB/Swiss-Prot
	EFh	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF47473	UniProtKB/Swiss-Prot
UniProt	B2CKC6	ENTREZGENE, UniProtKB/TrEMBL
	EFHC1_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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