Pex5 (peroxisomal biogenesis factor 5) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Pex5 (peroxisomal biogenesis factor 5) Mus musculus
Analyze
Symbol: Pex5
Name: peroxisomal biogenesis factor 5
RGD ID: 1316907
MGI Page MGI
Description: Predicted to enable peroxisome targeting sequence binding activity; protein carrier chaperone; and small GTPase binding activity. Involved in protein import into peroxisome matrix. Acts upstream of or within several processes, including fatty acid metabolic process; mitochondrial membrane organization; and nervous system development. Predicted to be located in Golgi apparatus; membrane; and peroxisome. Predicted to be part of protein-containing complex. Predicted to be active in cytosol; peroxisomal matrix; and peroxisomal membrane. Is expressed in central nervous system; dorsal root ganglion; genitourinary system; inner ear; and liver. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 2A; peroxisome biogenesis disorder 2B; and rhizomelic chondrodysplasia punctata type 5. Orthologous to human PEX5 (peroxisomal biogenesis factor 5).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AW212715; ESTM; ESTM1; peroxin 5; peroxin-5; peroxisomal C-terminal targeting signal import receptor; peroxisomal targeting signal 1 receptor; peroxisome biogenesis factor 5; peroxisome receptor 1; PT; PTS1 receptor; PTS1-BP; PTS1R; Px; Pxr1; PXR1P; X83306
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396124,373,774 - 124,392,878 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6124,373,775 - 124,392,026 (-)EnsemblGRCm39 Ensembl
GRCm386124,396,816 - 124,415,944 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6124,396,816 - 124,415,067 (-)EnsemblGRCm38mm10GRCm38
MGSCv376124,346,834 - 124,365,085 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366124,362,437 - 124,380,668 (-)NCBIMGSCv36mm8
Celera6126,087,349 - 126,105,596 (-)NCBICelera
Cytogenetic Map6F2NCBI
cM Map659.15NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
cytosol  (IBA,ISO,ISS,TAS)
Golgi apparatus  (IEA,ISO)
membrane  (IEA,ISO)
mitochondrion  (IEA)
peroxisomal matrix  (ISO,ISS)
peroxisomal membrane  (IBA,ISO)
peroxisome  (ISO)
protein-containing complex  (IEA,ISO)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal axon morphology  (IAGP)
abnormal bile salt homeostasis  (IAGP)
abnormal blood homeostasis  (IAGP)
abnormal brain white matter morphology  (IAGP)
abnormal breathing pattern  (IAGP)
abnormal cell morphology  (IAGP)
abnormal cerebral cortex morphology  (IAGP)
abnormal endoplasmic reticulum morphology  (IAGP)
abnormal fatty acid beta-oxidation  (IAGP)
abnormal glial cell morphology  (IAGP)
abnormal glucose homeostasis  (IAGP)
abnormal inflammatory response  (IAGP)
abnormal kidney morphology  (IAGP)
abnormal liver morphology  (IAGP)
abnormal lysosome morphology  (IAGP)
abnormal mitochondrial ATP synthesis coupled electron transport  (IAGP)
abnormal mitochondrial crista morphology  (IAGP)
abnormal mitochondrial inner membrane morphology  (IAGP)
abnormal mitochondrial shape  (IAGP)
abnormal myelination  (IAGP)
abnormal oligodendrocyte morphology  (IAGP)
abnormal postnatal growth  (IAGP)
abnormal respiratory electron transport chain  (IAGP)
abnormal seminiferous tubule morphology  (IAGP)
abnormal testis morphology  (IAGP)
ataxia  (IAGP)
decreased body weight  (IAGP)
decreased testis weight  (IAGP)
delayed brain development  (IAGP)
delayed intestine development  (IAGP)
delayed kidney development  (IAGP)
embryonic growth retardation  (IAGP)
enlarged liver  (IAGP)
gliosis  (IAGP)
hindlimb paralysis  (IAGP)
hindlimb paresis  (IAGP)
increased circulating lactate level  (IAGP)
increased liver tumor incidence  (IAGP)
kyphosis  (IAGP)
liver hyperplasia  (IAGP)
male infertility  (IAGP)
microgliosis  (IAGP)
muscle weakness  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
premature death  (IAGP)
respiratory distress  (IAGP)
seminiferous tubule degeneration  (IAGP)
slow postnatal weight gain  (IAGP)
tremors  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. A mouse model for Zellweger syndrome. Baes M, etal., Nat Genet. 1997 Sep;17(1):49-57.
2. Mitochondrial alterations caused by defective peroxisomal biogenesis in a mouse model for Zellweger syndrome (PEX5 knockout mouse). Baumgart E, etal., Am J Pathol. 2001 Oct;159(4):1477-94. doi: 10.1016/S0002-9440(10)62534-5.
3. Absence of peroxisomes in mouse hepatocytes causes mitochondrial and ER abnormalities. Dirkx R, etal., Hepatology. 2005 Apr;41(4):868-78.
4. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. MGD IEA MGD IEA
7. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. Hepatosteatosis in peroxisome deficient liver despite increased β-oxidation capacity and impaired lipogenesis. Peeters A, etal., Biochimie. 2011 Oct;93(10):1828-38. doi: 10.1016/j.biochi.2011.06.034. Epub 2011 Jul 5.
10. Mouse MP Annotation Import Pipeline RGD automated import pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Mitochondrial disruption in peroxisome deficient cells is hepatocyte selective but is not mediated by common hepatic peroxisomal metabolites. Shinde AB, etal., Mitochondrion. 2018 Mar;39:51-59. doi: 10.1016/j.mito.2017.08.013. Epub 2017 Sep 1.
14. Genetic mapping of 20 novel expressed sequence tags from midgestation mouse embryos suggests chromosomal clustering. Tchernev VT, etal., Genomics 1997 Feb 15;40(1):170-4.
15. Database resources of the National Center for Biotechnology Information. Wheeler DL, etal., Nucleic Acids Res 2001 Jan 1;29(1):11-6.
Additional References at PubMed
PMID:7490078   PMID:9668159   PMID:10349636   PMID:10653000   PMID:11042159   PMID:11076861   PMID:11161822   PMID:11171065   PMID:11217851   PMID:11420171   PMID:11463335   PMID:11792727  
PMID:11829486   PMID:11857813   PMID:12477932   PMID:12520002   PMID:14586000   PMID:14610273   PMID:15102471   PMID:15241609   PMID:15489334   PMID:16141072   PMID:16141073   PMID:16484321  
PMID:17317787   PMID:17442273   PMID:17643102   PMID:18287559   PMID:18400901   PMID:19830841   PMID:20138876   PMID:20578053   PMID:21267068   PMID:21620837   PMID:21873635   PMID:21976670  
PMID:22002056   PMID:22458306   PMID:23141464   PMID:24319055   PMID:25450972   PMID:26086376   PMID:27113764   PMID:28470148   PMID:28671696   PMID:31176039   PMID:31996685   PMID:32554809  
PMID:32777345   PMID:33143123   PMID:33378226   PMID:33389129   PMID:34321999   PMID:35074867   PMID:35191396   PMID:36433756   PMID:36584717   PMID:36906951  


Genomics

Comparative Map Data
Pex5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396124,373,774 - 124,392,878 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6124,373,775 - 124,392,026 (-)EnsemblGRCm39 Ensembl
GRCm386124,396,816 - 124,415,944 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6124,396,816 - 124,415,067 (-)EnsemblGRCm38mm10GRCm38
MGSCv376124,346,834 - 124,365,085 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366124,362,437 - 124,380,668 (-)NCBIMGSCv36mm8
Celera6126,087,349 - 126,105,596 (-)NCBICelera
Cytogenetic Map6F2NCBI
cM Map659.15NCBI
PEX5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38127,188,653 - 7,218,574 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl127,188,685 - 7,218,574 (+)EnsemblGRCh38hg38GRCh38
GRCh37127,341,249 - 7,371,170 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36127,234,225 - 7,255,343 (+)NCBINCBI36Build 36hg18NCBI36
Build 34127,234,223 - 7,255,342NCBI
Celera128,917,914 - 8,946,785 (+)NCBICelera
Cytogenetic Map12p13.31NCBI
HuRef127,154,705 - 7,183,873 (+)NCBIHuRef
CHM1_1127,340,679 - 7,369,353 (+)NCBICHM1_1
T2T-CHM13v2.0127,201,809 - 7,231,939 (+)NCBIT2T-CHM13v2.0
Pex5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84158,956,973 - 158,983,581 (-)NCBIGRCr8
mRatBN7.24157,270,671 - 157,296,432 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4157,270,672 - 157,296,431 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4163,487,111 - 163,512,826 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04159,270,018 - 159,295,731 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04157,915,420 - 157,941,178 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04156,983,914 - 157,009,675 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4156,403,016 - 156,427,755 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl4156,983,915 - 157,009,674 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04224,003,341 - 224,029,474 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.04223,418,715 - 223,444,193 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44160,567,258 - 160,595,985 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14160,813,343 - 160,858,163 (-)NCBI
Celera4146,011,937 - 146,037,676 (-)NCBICelera
Cytogenetic Map4q42NCBI
Pex5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554134,736,189 - 4,755,766 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554134,736,189 - 4,755,559 (+)NCBIChiLan1.0ChiLan1.0
PEX5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21012,753,209 - 12,775,098 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11212,750,866 - 12,771,857 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0127,318,637 - 7,340,428 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1127,235,049 - 7,255,815 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl127,235,049 - 7,255,815 (+)Ensemblpanpan1.1panPan2
PEX5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12737,843,218 - 37,860,664 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2737,809,717 - 37,860,376 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha278,756,138 - 8,773,549 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02738,196,735 - 38,214,157 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2738,196,420 - 38,214,129 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12738,070,618 - 38,088,021 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02738,111,918 - 38,129,293 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0278,233,881 - 8,251,302 (+)NCBIUU_Cfam_GSD_1.0
Pex5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945101,919,747 - 101,938,591 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936709587,295 - 606,247 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936709587,296 - 606,085 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PEX5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl563,542,431 - 63,562,849 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1563,542,422 - 63,562,762 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2565,936,442 - 65,956,834 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PEX5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1117,255,078 - 7,286,500 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl117,256,182 - 7,274,938 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666063923,792 - 955,255 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pex5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248603,771,963 - 3,790,985 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248603,771,949 - 3,790,982 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2499
Count of miRNA genes:556
Interacting mature miRNAs:649
Transcripts:ENSMUST00000035861, ENSMUST00000080557, ENSMUST00000112530, ENSMUST00000112531, ENSMUST00000112532, ENSMUST00000150812, ENSMUST00000150899, ENSMUST00000156415
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142079Skmw15_mskeletal muscle weight 15 (mouse)Not determined6116829851149588044Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683690851146954059Mouse
11252138Clas1_mcarcinogen-induced lung adenoma susceptibility 1 (mouse)6112246918146954059Mouse
10449436Pas17_mpulmonary adenoma susceptibility 17 (mouse)6124334273145601739Mouse
1300887Pabr1_mplasma apolipoprotein B (human) regulator 1 (mouse)Not determined6103754405136400690Mouse
1301915Chab3_mcholesterol absorption 3 (mouse)Not determined698908709132916997Mouse
1301083Bhr5_mbronchial hyperresponsiveness 5 (mouse)Not determined6115694477132578150Mouse
1301658Radpf3_mradiation pulmonary fibrosis 3 (mouse)Not determined6115219814146330736Mouse
10043923Bhr7_mbronchial hyperresponsiveness 7 (mouse)Not determined698219814132219938Mouse
4140980Mvwf2_mmodifier of von Willebrand factor 2 (mouse)Not determined114345693145601739Mouse
4141940W6q5_mweight 6 weeks QTL 5 (mouse)Not determined96632912146535124Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648696934125336963Mouse
4141295Rua_mraffinose acetate tasting (mouse)Not determined115546805149549364Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
1301509Sluc3_msusceptibility to lung cancer 3 (mouse)Not determined6104480321127019938Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648703490125333748Mouse
1301518Bbaa5_mB.burgdorferi-associated arthritis 5 (mouse)Not determined698483798145881170Mouse
11353842Bmiq4_mbody mass index QTL 4 (mouse)692584287146330736Mouse
1302131Bmd8_mbone mineral density 8 (mouse)Not determined699132089133132228Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645290993128811995Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
1357555Tesq2_mtestis weight QTL 2 (mouse)Not determined696632912146535124Mouse
10043891Tilss4_mTNF-induced lethal shock susceptibility 3 (mouse)Not determined6112246918125333748Mouse
1301244Ichs_mimmediate cutaneous hypersensitivity QTL (mouse)Not determined690772571124772807Mouse
4142416Egq11_mearly growth QTL 11 (mouse)Not determined96632912146535124Mouse
1301923Lith6_mlithogenic gene 6 (mouse)Not determined698694477132694676Mouse
10412207Cypr5_mcytokine production 5 (mouse)Not determined6110815180144815323Mouse
1300704Cia3_mcollagen induced arthritis QTL 3 (mouse)Not determined696324286130324483Mouse
1301152Athsq2_matherosclerosis susceptibility QTL 2 (mouse)Not determined6117059949149588044Mouse
1301927Etohcta6_methanol conditioned taste aversion 6 (mouse)Not determined6115578005149578150Mouse
13463481Mcvq14_mmean corpuscular volume QTL 14 (mouse)6111142448145142541Mouse
4141194Cyx_mcycloheximide tasting (mouse)Not determined115546805149549364Mouse
4141064Ath37_matherosclerosis 37 (mouse)Not determined6116641858128495988Mouse
1357806Aaj3_manxiety in A/J 3 (mouse)Not determined6104480321136400690Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673476983134676963Mouse
4141889Qui_mquinine sensitivity, taste (mouse)Not determined115546805149549364Mouse
1301804Bulb2_mbulb size 2 (mouse)Not determined6120416806149588044Mouse
1301292Cfbw2_mcystic fibrosis body weight 2 (mouse)Not determined694981612128981699Mouse
11040599Lmr4b_mleishmaniasis resistance 4b (mouse)696324286130324483Mouse

Markers in Region
AW212715  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386124,397,053 - 124,397,199UniSTSGRCm38
MGSCv376124,347,071 - 124,347,217UniSTSGRCm37
Celera6126,087,586 - 126,087,732UniSTS
Cytogenetic Map6F2UniSTS
cM Map659.6UniSTS
Whitehead/MRC_RH61267.8UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001277330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001277805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001360570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_175933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_176972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_176973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC124470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ416473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC029748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY122705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY442904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF724027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z97018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000035861   ⟹   ENSMUSP00000049132
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6124,373,791 - 124,391,996 (-)Ensembl
GRCm38.p6 Ensembl6124,396,832 - 124,415,037 (-)Ensembl
Ensembl Acc Id: ENSMUST00000080557   ⟹   ENSMUSP00000079398
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6124,373,776 - 124,392,026 (-)Ensembl
GRCm38.p6 Ensembl6124,396,817 - 124,415,067 (-)Ensembl
Ensembl Acc Id: ENSMUST00000112530   ⟹   ENSMUSP00000108149
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6124,373,776 - 124,391,392 (-)Ensembl
GRCm38.p6 Ensembl6124,396,817 - 124,414,433 (-)Ensembl
Ensembl Acc Id: ENSMUST00000112531   ⟹   ENSMUSP00000108150
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6124,373,776 - 124,391,822 (-)Ensembl
GRCm38.p6 Ensembl6124,396,817 - 124,414,863 (-)Ensembl
Ensembl Acc Id: ENSMUST00000112532   ⟹   ENSMUSP00000108151
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6124,373,775 - 124,392,026 (-)Ensembl
GRCm38.p6 Ensembl6124,396,816 - 124,415,067 (-)Ensembl
Ensembl Acc Id: ENSMUST00000150812
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6124,381,272 - 124,382,326 (-)Ensembl
GRCm38.p6 Ensembl6124,404,313 - 124,405,367 (-)Ensembl
Ensembl Acc Id: ENSMUST00000150899
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6124,380,089 - 124,391,001 (-)Ensembl
GRCm38.p6 Ensembl6124,403,130 - 124,414,042 (-)Ensembl
Ensembl Acc Id: ENSMUST00000156415
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6124,374,870 - 124,376,573 (-)Ensembl
GRCm38.p6 Ensembl6124,397,911 - 124,399,614 (-)Ensembl
RefSeq Acc Id: NM_001277330   ⟹   NP_001264259
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396124,373,774 - 124,391,822 (-)NCBI
GRCm386124,396,816 - 124,414,863 (-)NCBI
Celera6126,087,349 - 126,105,596 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001277805   ⟹   NP_001264734
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396124,373,774 - 124,392,010 (-)NCBI
GRCm386124,396,816 - 124,415,067 (-)NCBI
Celera6126,087,349 - 126,105,596 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001360570   ⟹   NP_001347499
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396124,373,774 - 124,392,878 (-)NCBI
GRCm386124,396,816 - 124,415,855 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001410279   ⟹   NP_001397208
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396124,373,774 - 124,391,822 (-)NCBI
RefSeq Acc Id: NM_001410280   ⟹   NP_001397209
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396124,373,774 - 124,392,878 (-)NCBI
RefSeq Acc Id: NM_001410281   ⟹   NP_001397210
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396124,373,774 - 124,392,010 (-)NCBI
RefSeq Acc Id: NM_008995   ⟹   NP_033021
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396124,373,774 - 124,392,010 (-)NCBI
GRCm386124,396,816 - 124,415,067 (-)NCBI
MGSCv376124,346,834 - 124,365,085 (-)RGD
Celera6126,087,349 - 126,105,596 (-)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_175933   ⟹   NP_787947
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396124,373,774 - 124,392,010 (-)NCBI
GRCm386124,396,816 - 124,415,067 (-)NCBI
MGSCv376124,346,834 - 124,365,085 (-)RGD
Celera6126,087,349 - 126,105,596 (-)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_176972
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396124,373,774 - 124,392,010 (-)NCBI
RefSeq Acc Id: NR_176973
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396124,373,774 - 124,392,010 (-)NCBI
RefSeq Acc Id: NP_787947   ⟸   NM_175933
- Peptide Label: isoform 2
- UniProtKB: O09012 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_033021   ⟸   NM_008995
- Peptide Label: isoform 1
- UniProtKB: Q8K2V5 (UniProtKB/Swiss-Prot),   Q3UM58 (UniProtKB/Swiss-Prot),   Q91YC7 (UniProtKB/Swiss-Prot),   O09012 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001264734   ⟸   NM_001277805
- Peptide Label: isoform 1
- UniProtKB: Q8K2V5 (UniProtKB/Swiss-Prot),   Q3UM58 (UniProtKB/Swiss-Prot),   Q91YC7 (UniProtKB/Swiss-Prot),   O09012 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001264259   ⟸   NM_001277330
- Peptide Label: isoform 2
- UniProtKB: O09012 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001347499   ⟸   NM_001360570
- Peptide Label: isoform 2
Ensembl Acc Id: ENSMUSP00000108149   ⟸   ENSMUST00000112530
Ensembl Acc Id: ENSMUSP00000108151   ⟸   ENSMUST00000112532
Ensembl Acc Id: ENSMUSP00000108150   ⟸   ENSMUST00000112531
Ensembl Acc Id: ENSMUSP00000049132   ⟸   ENSMUST00000035861
Ensembl Acc Id: ENSMUSP00000079398   ⟸   ENSMUST00000080557
RefSeq Acc Id: NP_001397209   ⟸   NM_001410280
- Peptide Label: isoform 1
- UniProtKB: Q8K2V5 (UniProtKB/Swiss-Prot),   Q3UM58 (UniProtKB/Swiss-Prot),   O09012 (UniProtKB/Swiss-Prot),   Q91YC7 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001397210   ⟸   NM_001410281
- Peptide Label: isoform 3
- UniProtKB: D3Z600 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001397208   ⟸   NM_001410279
- Peptide Label: isoform 1
- UniProtKB: Q8K2V5 (UniProtKB/Swiss-Prot),   Q3UM58 (UniProtKB/Swiss-Prot),   O09012 (UniProtKB/Swiss-Prot),   Q91YC7 (UniProtKB/Swiss-Prot)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O09012-F1-model_v2 AlphaFold O09012 1-639 view protein structure

Promoters
RGD ID:6839742
Promoter ID:MM_KWN:47531
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Liver,   Spleen
Transcripts:OTTMUST00000055936
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv366124,349,839 - 124,350,339 (-)MPROMDB
RGD ID:6839737
Promoter ID:MM_KWN:47532
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:OTTMUST00000055935
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv366124,356,061 - 124,356,561 (-)MPROMDB
RGD ID:6839191
Promoter ID:MM_KWN:47533
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:AK085835_D830015G05RIK,   ENSMUST00000112530,   ENSMUST00000112531,   LINCRNA_872,   NM_008995,   NM_175933,   OTTMUST00000055934,   UC009DQU.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv366124,363,476 - 124,366,177 (+)MPROMDB
RGD ID:6890956
Promoter ID:EPDNEW_M8929
Type:multiple initiation site
Name:Pex5_1
Description:Mus musculus peroxisomal biogenesis factor 5 , transcript variant2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386124,415,051 - 124,415,111EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1098808 AgrOrtholog
Ensembl Genes ENSMUSG00000005069 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000035861 ENTREZGENE
  ENSMUST00000035861.6 UniProtKB/Swiss-Prot
  ENSMUST00000080557 ENTREZGENE
  ENSMUST00000080557.12 UniProtKB/Swiss-Prot
  ENSMUST00000112530 ENTREZGENE
  ENSMUST00000112530.8 UniProtKB/TrEMBL
  ENSMUST00000112531 ENTREZGENE
  ENSMUST00000112531.8 UniProtKB/Swiss-Prot
  ENSMUST00000112532 ENTREZGENE
  ENSMUST00000112532.8 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro PTS1R_family UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:19305 UniProtKB/Swiss-Prot
MGD MGI:1098808 ENTREZGENE
NCBI Gene 19305 ENTREZGENE
PANTHER PTHR10130 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10130:SF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TPR_16 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pex5 PhenoGen
PROSITE TPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_REGION UniProtKB/Swiss-Prot
SMART TPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D3Z600 ENTREZGENE, UniProtKB/TrEMBL
  O09012 ENTREZGENE, UniProtKB/Swiss-Prot
  Q3UM58 ENTREZGENE
  Q8K2V5 ENTREZGENE
  Q91YC7 ENTREZGENE
UniProt Secondary Q3UM58 UniProtKB/Swiss-Prot
  Q8K2V5 UniProtKB/Swiss-Prot
  Q91YC7 UniProtKB/Swiss-Prot