Abhd8 (abhydrolase domain containing 8)

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Gene: Abhd8 (abhydrolase domain containing 8) Mus musculus

Analyze

Symbol:

Abhd8

Name:

abhydrolase domain containing 8

RGD ID:

1313871

MGI Page

MGI

Description:

Predicted to have carboxylic ester hydrolase activity and lysophosphatidic acid acyltransferase activity. Predicted to be involved in lipid homeostasis and phosphatidic acid biosynthetic process. Predicted to localize to mitochondrion. Is expressed in several structures, including adrenal gland; gallbladder; genitourinary system; gut; and nervous system. Orthologous to human ABHD8 (abhydrolase domain containing 8); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

0910001L24Rik; AB030191; abhydrolase domain-containing protein 8; alpha/beta hydrolase domain-containing protein 8

RGD Orthologs

Human

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ABHD8 (abhydrolase domain containing 8)	HGNC	Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Abhd8 (abhydrolase domain containing 8)	HGNC	Treefam, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Abhd8 (abhydrolase domain containing 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ABHD8 (abhydrolase domain containing 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ABHD8 (abhydrolase domain containing 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Abhd8 (abhydrolase domain containing 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ABHD8 (abhydrolase domain containing 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	ABHD8 (abhydrolase domain containing 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Abhd8 (abhydrolase domain containing 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Abhd8 (abhydrolase domain containing 8)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Homo sapiens (human):	ABHD8 (abhydrolase domain containing 8)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|Roundup\|TreeFam)
Danio rerio (zebrafish):	abhd8a (abhydrolase domain containing 8a)	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|Roundup\|TreeFam\|ZFIN)
Danio rerio (zebrafish):	abhd8b (abhydrolase domain containing 8b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam\|ZFIN)

Latest Assembly:

GRCm38 - Mouse Genome Assembly GRCm38

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	71,909,344 - 71,917,351 (-)	NCBI	GRCm39		mm39
GRCm38	8	71,456,700 - 71,464,707 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	71,456,705 - 71,463,655 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	73,980,599 - 73,987,556 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	8	74,385,694 - 74,392,635 (-)	NCBI			mm8
Celera	8	73,975,916 - 73,982,874 (-)	NCBI		Celera
Cytogenetic Map	8	B3.3	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2-hydroxypropanoic acid (ISO)

2-methylcholine (ISO)

3,4-methylenedioxymethamphetamine (EXP)

3-chloropropane-1,2-diol (ISO)

4-hydroxyphenyl retinamide (EXP)

acetamide (ISO)

acrylamide (ISO)

benzo[a]pyrene (EXP,ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (ISO)

C60 fullerene (ISO)

clofibrate (EXP)

dibutyl phthalate (EXP,ISO)

ethanol (EXP)

fenvalerate (ISO)

indole-3-methanol (ISO)

lead(0) (ISO)

lead(2+) (ISO)

N-nitrosodiethylamine (ISO)

pirinixic acid (EXP,ISO)

propanal (ISO)

rac-lactic acid (ISO)

silicon dioxide (EXP)

toluene (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

lipid homeostasis (IBA)

phosphatidic acid biosynthetic process (IBA)

Cellular Component

mitochondrion (IBA)

Molecular Function

carboxylic ester hydrolase activity (IBA)

catalytic activity (IEA)

hydrolase activity (IEA)

lysophosphatidic acid acyltransferase activity (IBA)

protein binding (ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal adipose tissue amount (IEA)

abnormal body length (IEA)

abnormal circulating calcium level (IEA)

abnormal circulating chloride level (IEA)

abnormal circulating cholesterol level (IEA)

abnormal circulating potassium level (IEA)

abnormal locomotor activation (IEA)

abnormal skin coloration (IEA)

hyperactivity (IEA)

increased total body fat amount (IEA)

References

References - curated


1.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2.	MGD data from the GO Consortium
3.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:10349636	PMID:10679242	PMID:11042159	PMID:11076861	PMID:12477932	PMID:15489334	PMID:15782199	PMID:16141072	PMID:16141073	PMID:21267068	PMID:21677750
PMID:21873635	PMID:24194600	PMID:27626380	PMID:30157441

Genomics

Comparative Map Data

Abhd8
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	71,909,344 - 71,917,351 (-)	NCBI	GRCm39		mm39
GRCm38	8	71,456,700 - 71,464,707 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	71,456,705 - 71,463,655 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	73,980,599 - 73,987,556 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	8	74,385,694 - 74,392,635 (-)	NCBI			mm8
Celera	8	73,975,916 - 73,982,874 (-)	NCBI		Celera
Cytogenetic Map	8	B3.3	NCBI

ABHD8
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	19	17,292,131 - 17,310,236 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	19	17,292,131 - 17,303,425 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	19	17,402,940 - 17,414,282 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	17,263,940 - 17,275,282 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	19	17,263,940 - 17,275,234	NCBI
Celera	19	17,304,682 - 17,316,010 (-)	NCBI
Cytogenetic Map	19	p13.11	NCBI
HuRef	19	16,969,585 - 16,980,841 (-)	NCBI		HuRef
CHM1_1	19	17,402,410 - 17,413,755 (-)	NCBI		CHM1_1

Abhd8
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	16	19,866,028 - 19,872,765 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	19,866,022 - 19,872,774 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	19,727,394 - 19,734,131 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	18,628,138 - 18,634,875 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	16	18,628,150 - 18,634,815 (-)	NCBI
Celera	16	18,349,543 - 18,356,280 (-)	NCBI		Celera
Cytogenetic Map	16	p14	NCBI

Abhd8
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955524	925,102 - 930,270 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955524	924,128 - 932,046 (+)	NCBI	ChiLan1.0	ChiLan1.0

ABHD8
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	19	17,755,973 - 17,765,502 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	17,755,973 - 17,765,502 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	19	16,780,132 - 16,791,233 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

ABHD8
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	20	45,449,871 - 45,459,506 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	20	45,448,457 - 45,459,507 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Abhd8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936596	3,559,139 - 3,567,626 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ABHD8
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	60,380,705 - 60,388,986 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	60,380,691 - 60,388,986 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

ABHD8
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	15,798,462 - 15,810,012 (-)	NCBI
ChlSab1.1 Ensembl	6	15,798,256 - 15,810,036 (-)	Ensembl

Abhd8
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624908	641,181 - 648,366 (+)	NCBI

Position Markers

RH125067

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	8	71,465,498 - 71,465,620	UniSTS	GRCm38
MGSCv37	8	73,989,397 - 73,989,519	UniSTS	GRCm37
Celera	8	73,984,715 - 73,984,837	UniSTS
Cytogenetic Map	8	C1	UniSTS
Cytogenetic Map	8	B3.3	UniSTS

QTLs in Region (GRCm38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
14747005	Mancz7_m	mandible centroid size 7 (mouse)					8	50053306	84053306	Mouse
27226754	Femd6_m	femur midshaft diameter 6, 10 week (mouse)					8	37400000	109600000	Mouse
10766466	Char12_m	P. chabaudi malaria resistance QTL 12 (mouse)					8	68269827	82600347	Mouse
1301872	Cd4ts3_m	CD4 T cell subset 3 (mouse)			Not determined		8	71396181	105396393	Mouse
1301952	Im3_m	immunoregulatory 3 (mouse)			Not determined		8	54706614	88706763	Mouse
14700686	Civq3_m	cerebral infarct volume QTL 3 (mouse)					8	51882191	85882191	Mouse
1357787	Vtbt5_m	vertebral trabecular bone trait 5 (mouse)			Not determined		8	65357768	99357920	Mouse
1301544	Iba3_m	induction of brown adipocytes 3 (mouse)			Not determined		8	44294880	78295025	Mouse
4142283	Imraq2_m	immune response to AAV2 QTL 2 (mouse)			Not determined		8	70305375	104305495	Mouse
1301441	Skull11_m	skull morphology 11 (mouse)			Not determined		8	47737134	81737254	Mouse
4141395	Char2a_m	P. chabaudi malaria resistance QTL 2a (mouse)			Not determined			71136783	90202598	Mouse
10766453	Char11_m	P. chabaudi malaria resistance QTL 11 (mouse)					8	47637030	81637146	Mouse
10412287	Carg3_m	Candida albicans resistance gene 3 (mouse)			Not determined		8	55545028	89545028	Mouse
14746987	Manh64_m	mandible shape 64 (mouse)					8	50053306	84053306	Mouse
1558875	Eae31_m	experimental allergic encephalomyelitis susceptibility 31 (mouse)			Not determined		8	34642776	114837007	Mouse
12904744	Carcdq1_m	cardiac collagen deposition QTL 1 (mouse)					8	39709256	94689598	Mouse
4141797	Skmw16_m	skeletal muscle weight 16 (mouse)			Not determined		8	63939547	97939696	Mouse
1301767	Fcsa2_m	femoral cross-sectional area 2 (mouse)			Not determined		8	70305375	104305495	Mouse
4142023	W3q5_m	weight 3 weeks QTL 5 (mouse)			Not determined			71287817	123895615	Mouse
10043992	Hbnr11_m	Heligmosomoides bakeri nematode resistance 11 (mouse)			Not determined		8	65600207	99600347	Mouse
1357708	Orq1_m	ovulation rate QTL 1 (mouse)			Not determined		8	71287817	123895615	Mouse
10043975	Obq31_m	obesity QTL 31 (mouse)			Not determined		8	58409776	92409776	Mouse
1558780	Idd22_m	insulin dependent diabetes susceptibility 22 (mouse)			Not determined		8	71102903	105103009	Mouse
4141285	Tgq18_m	triglyceride QTL 18 (mouse)			Not determined			63460107	97460107	Mouse
11353828	Gf7_m	gonadal fat pad weight 7 (mouse)					8	58201479	92201479	Mouse
1301506	Aevm1_m	autoimmune extremity vasculitis in MRL mice 1 (mouse)			Not determined		8	54287817	88287993	Mouse
1301013	Capsq4_m	capsaicin sensitivity related QTL 4 (mouse)			Not determined		8	36163000	92728652	Mouse
4140967	Bmd39_m	bone mineral density 39 (mouse)			Not determined		8	32016544	117238700	Mouse
1357715	Alaa3_m	alopecia areata 3 (mouse)			Not determined		8	48792939	82793021	Mouse
1301688	Orch6_m	autoimmune orchitis resistance 6 (mouse)			Not determined		8	60786850	94786976	Mouse
1301717	Adip4_m	adiposity 4 (mouse)			Not determined		8	47637030	81637146	Mouse

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	243
Count of miRNA genes:	183
Interacting mature miRNAs:	215
Transcripts:	ENSMUST00000008094
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_022419	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_030243705	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_036154226	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB030191	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC127416	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK003090	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK037669	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK080618	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK155503	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK177261	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK178673	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK178904	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK178916	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK179035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK181179	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK181236	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK181691	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK184390	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK185006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK185637	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK187254	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK189463	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK205860	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK207815	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK207833	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK209444	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK212822	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC026540	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466569	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSMUST00000008094 ⟹ ENSMUSP00000008094

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	8	71,456,705 - 71,463,655 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000212321

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	8	71,457,325 - 71,458,907 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000212503

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	8	71,459,504 - 71,463,622 (-)	Ensembl

RefSeq Acc Id:

NM_022419 ⟹ NP_071864

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	8	71,909,344 - 71,916,301 (-)	NCBI
GRCm38	8	71,456,700 - 71,463,657 (-)	ENTREZGENE
MGSCv37	8	73,980,599 - 73,987,556 (-)	RGD
Celera	8	73,975,916 - 73,982,874 (-)	RGD
cM Map	8		ENTREZGENE

Sequence:

show sequence

GTGGGACTTACAGGGCCGGTTTGCTACGCGGCTGCGGGATGCCCCTGCGTTGACCGTCCGGGCC
CGCGCCTGTCCGCGCTAATGCGGCCAACCCCGCACCACCATGTAAGCGGCACCTGCAGGTGGAC
GCTGGCTTCTCCGCCCGGGACCCCTGCGTCCTGCCTCGGGCCCCGGGCCCCTCGATGACCTCAG
AACACACCATGCTGACTGGGGTGACAGATGGCTTTTTCTGCTGCCTGCTGGGGACTCCCCCTAA
CGCCGTGCGGCCACTGGAGAGTGTCGAGTCCAGTGACGGCTACACATTCGTGGAGGTCAAGCCA
GGCCGGGTGCTGCGGGTAAAGCATGCGGGGCCCGCGCCCATCCCCACGCCGCCACCACCACCTC
CTGAAGATGATCCAGGGGTCAAGACGGGCCTTGTGCGCTGCCAGCGCCGTATCACAGTGTACCG
CAACGGGAGGCTGGTGGTGGAGAACCTGGGCCGAGCGCCTCGTGCCGACCTGCAAGGCCGCAGT
GGCTCCGGGGACCCGCCTGCTGCACTCGAGGTTGAGCTGGCTGAGCCCGCAGGAGGAGACACCC
GGGCCAACCCAGGCAGCGGGCGACGGCGCCGCCCACGGCGTCCGAAGAGGACCATCCACATCGA
CTGTGAGCAGCGCATCACCAGCTGCAAGGGTGCGCAGGCTGATGTGGTGCTGTTCTTCATTCAC
GGAGTCGGTGGCTCACTCGCCATCTGGAAGGAGCAGCTAGACTTCTTTGTGCGACTCGGCTATG
AGGTGGTGGCACCTGACCTGGCGGGCCATGGAGCCAGCTCTGCGCCGCAGGTGGCAGCTGCCTA
CACCTTTTACGCATTGGCAGAGGATATGAGGGCCATCTTCACACGCTATGCCAAGAAGCGCAAT
GTGCTCATCGGCCATTCTTACGGTGTCTCCTTCTGTACTTTCCTGGCCCACGAGTACCCAGATC
TTGTACACAAAGTGATCATGATCAACGGTGGGGGCCCCACGGCACTGGAGCCCAGCCTATGCTC
CATCTTCAACATGCCCACATGTGTCCTGCACTGCCTGTCACCTTGCCTGGCCTGGAGTTTCCTC
AAGGCCGGCTTTGCCCGCCAAGGGGCCAAAGAAAAGCAGCTGCTGAAGGAGGGCAATGCGTTCA
ATGTGTCCTCCTTCGTGCTGCGGGCCATGATGAGTGGCCAGTATTGGCCTGAAGGCGACGAGGT
CTACCACGCGGAGCTGACGGTACCCGTGCTGCTAGTGCACGGCATGCACGACAAATTTGTGCCA
GTGGAAGAGGACCAACGCATGGCTGAGATCCTGCTGCTGGCCTTTCTCAAGCTCATCGAGGAAG
GCAGCCACATGGTGATGCTGGAGTGTCCTGAAACGGTCAACACGCTGTTACACGAGTTCCTGCT
GTGGGAGCCAGAACCCGAGGCTGAGCCAAAGCTCGAGCCAAAGCCCAAGCCACAGCTGCTGCAG
CCAGAGCCGGCTCCAGGGGAGGAGAAGTGACCAGCGGCGCAGGGACTCCTGGATCTTGAGTAGT
AGAGGCTCTTAGACTGGGCGTGGGCTGGCTGGGCGGGGCCTCATGCCGATGGGCGGGGCCTGGG
CATGCCCCAGAGCGAACCAGGCACAGTCAGTGTTGGAGACTCAGTGCCCAGGGCAGCTATGGTG
CCCTTTCCACGCGCGACCGAAGGGTGTGACCTTGTACAGAGCCCCCTCCCTGCCTCCCCGAGTC
CCTGAAGCTGCAGCGCGCGGGCTGCCATCCCACTCGGTCTTCCCCTCCGCTGTGCTCCATTCCG
CACTGGGAAGCCCTAAGGAGAATCCTGGGGAAGGGCTCCTATCCTGTCCTGGGAGACCCTACCG
CGCCATCCCCATTGCTTGGGACTGGGAGCTAGGCACCCAAGGAGGGAGGGGTCGGAGCCACAAA
TCCCCGCATATGGCAACTTGTAAGTCAATAAAATAATAATAATAAAAAAGACAATCCAAACTGG
C

hide sequence

RefSeq Acc Id:

XM_030243705 ⟹ XP_030099565

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	8	71,909,349 - 71,917,351 (-)	NCBI
GRCm38	8	71,456,705 - 71,464,707 (-)	NCBI

Sequence:

show sequence

CTGGTAGAGGGCGCCCCAGAGTGGTGGTGACGACTCTGGCAGCAGTCTGGAGAACTGGCTGCTG
GCCTTTTCACCCGCCCTCATTGAAGACGGGCAGCTGGCACGCAGCGGGCTGGCAGCTTCTTGGC
GCCCGCAGCCAAGACTTCTCTTGGCGCGCGGCCCGGATGTCCTTGAGTTCCAGCTCTTCATAAT
CTCGAAAACTCGTGCGTTGTGAATTTGCTCTGGGGTGGGGCTGCTGCTTGCAGACCGCGCGCTG
ATCCTGGGAAGAGAAGCCTCTGGTTGGACGGTTATCTAGGCCAGACGGCTCGCCGCTGCCATAG
GCCGAGATGCCTGCCCATCTGCTCCAGGCCCCGCCCACGCTGGGTGGGACTTACAGGGCCGGTT
TGCTACGCGGCTGCGGGATGCCCCTGCGTTGACCGTCCGGGCCCGCGCCTGTCCGCGCTAATGC
GGCCAACCCCGCACCACCATGTAAGCGGCACCTGCAGGTGGACGCTGGCTTCTCCGCCCGGGAC
CCCTGCGTCCTGCCTCGGGCCCCGGGCCCCTCGATGACCTCAGAACACACCATGCTGACTGGGG
TGACAGATGGCTTTTTCTGCTGCCTGCTGGGGACTCCCCCTAACGCCGTGCGGCCACTGGAGAG
TGTCGAGTCCAGTGACGGCTACACATTCGTGGAGGTCAAGCCAGGCCGGGTGCTGCGGGTAAAG
CATGCGGGGCCCGCGCCCATCCCCACGCCGCCACCACCACCTCCTGAAGATGATCCAGGGGTCA
AGACGGGCCTTGTGCGCTGCCAGCGCCGTATCACAGTGTACCGCAACGGGAGGCTGGTGGTGGA
GAACCTGGGCCGAGCGCCTCGTGCCGACCTGCAAGGCCGCAGTGGCTCCGGGGACCCGCCTGCT
GCACTCGAGGTTGAGCTGGCTGAGCCCGCAGGAGGAGACACCCGGGCCAACCCAGGCAGCGGGC
GACGGCGCCGCCCACGGCGTCCGAAGAGGACCATCCACATCGACTGTGAGCAGCGCATCACCAG
CTGCAAGGGTGCGCAGGCTGATGTGGTGCTGTTCTTCATTCACGGAGTCGGTGGCTCACTCGCC
ATCTGGAAGGAGCAGCTAGACTTCTTTGTGCGACTCGGCTATGAGGTGGTGGCACCTGACCTGG
CGGGCCATGGAGCCAGCTCTGCGCCGCAGGTGGCAGCTGCCTACACCTTTTACGCATTGGCAGA
GGATATGAGGGCCATCTTCACACGCTATGCCAAGAAGCGCAATGTGCTCATCGGCCATTCTTAC
GGTGTCTCCTTCTGTACTTTCCTGGCCCACGAGTACCCAGATCTTGTACACAAAGTGATCATGA
TCAACGGTGGGGGCCCCACGGCACTGGAGCCCAGCCTATGCTCCATCTTCAACATGCCCACATG
TGTCCTGCACTGCCTGTCACCTTGCCTGGCCTGGAGTTTCCTCAAGGCCGGCTTTGCCCGCCAA
GGGGCCAAAGAAAAGCAGCTGCTGAAGGAGGGCAATGCGTTCAATGTGTCCTCCTTCGTGCTGC
GGGCCATGATGAGTGGCCAGTATTGGCCTGAAGGCGACGAGGTCTACCACGCGGAGCTGACGGT
ACCCGTGCTGCTAGTGCACGGCATGCACGACAAATTTGTGCCAGTGGAAGAGGACCAACGCATG
GCTGAGATCCTGCTGCTGGCCTTTCTCAAGCTCATCGAGGAAGGCAGCCACATGGTGATGCTGG
AGTGTCCTGAAACGGTCAACACGCTGTTACACGAGTTCCTGCTGTGGGAGCCAGAACCCGAGGC
TGAGCCAAAGCTCGAGCCAAAGCCCAAGCCACAGCTGCTGCAGCCAGAGCCGGCTCCAGGGGAG
GAGAAGTGACCAGCGGCGCAGGGACTCCTGGATCTTGAGTAGTAGAGGCTCTTAGACTGGGCGT
GGGCTGGCTGGGCGGGGCCTCATGCCGATGGGCGGGGCCTGGGCATGCCCCAGAGCGAACCAGG
CACAGTCAGTGTTGGAGACTCAGTGCCCAGGGCAGCTATGGTGCCCTTTCCACGCGCGACCGAA
GGGTGTGACCTTGTACAGAGCCCCCTCCCTGCCTCCCCGAGTCCCTGAAGCTGCAGCGCGCGGG
CTGCCATCCCACTCGGTCTTCCCCTCCGCTGTGCTCCATTCCGCACTGGGAAGCCCTAAGGAGA
ATCCTGGGGAAGGGCTCCTATCCTGTCCTGGGAGACCCTACCGCGCCATCCCCATTGCTTGGGA
CTGGGAGCTAGGCACCCAAGGAGGGAGGGGTCGGAGCCACAAATCCCCGCATATGGCAACTTGT
AAGTCAATAAAATAATAATAATAAAAAAGACAATCCAAA

hide sequence

RefSeq Acc Id:

XM_036154226 ⟹ XP_036010119

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	8	71,909,349 - 71,917,264 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_071864	(Get FASTA)	NCBI Sequence Viewer
	XP_030099565	(Get FASTA)	NCBI Sequence Viewer
	XP_036010119	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH26540	(Get FASTA)	NCBI Sequence Viewer
	BAA92755	(Get FASTA)	NCBI Sequence Viewer
	BAB22558	(Get FASTA)	NCBI Sequence Viewer
	BAE33297	(Get FASTA)	NCBI Sequence Viewer
	EDL28921	(Get FASTA)	NCBI Sequence Viewer
	Q8R0P8	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_071864 ⟸ NM_022419

- UniProtKB:

Q8R0P8 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MTSEHTMLTGVTDGFFCCLLGTPPNAVRPLESVESSDGYTFVEVKPGRVLRVKHAGPAPIPTPP
PPPPEDDPGVKTGLVRCQRRITVYRNGRLVVENLGRAPRADLQGRSGSGDPPAALEVELAEPAG
GDTRANPGSGRRRRPRRPKRTIHIDCEQRITSCKGAQADVVLFFIHGVGGSLAIWKEQLDFFVR
LGYEVVAPDLAGHGASSAPQVAAAYTFYALAEDMRAIFTRYAKKRNVLIGHSYGVSFCTFLAHE
YPDLVHKVIMINGGGPTALEPSLCSIFNMPTCVLHCLSPCLAWSFLKAGFARQGAKEKQLLKEG
NAFNVSSFVLRAMMSGQYWPEGDEVYHAELTVPVLLVHGMHDKFVPVEEDQRMAEILLLAFLKL
IEEGSHMVMLECPETVNTLLHEFLLWEPEPEAEPKLEPKPKPQLLQPEPAPGEEK

hide sequence

RefSeq Acc Id:	XP_030099565 ⟸ XM_030243705
- Peptide Label:	isoform X1

RefSeq Acc Id:

ENSMUSP00000008094 ⟸ ENSMUST00000008094

RefSeq Acc Id:	XP_036010119 ⟸ XM_036154226
- Peptide Label:	isoform X1

Protein Domains

AB hydrolase-1

Promoters

RGD ID:

8667393

Promoter ID:

EPDNEW_M11728

Type:

initiation region

Name:

Abhd8_1

Description:

Mus musculus abhydrolase domain containing 8 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	8	71,463,648 - 71,463,708	EPDNEW

RGD ID:

6848243

Promoter ID:

MM_ACW:47892

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Brain

Transcripts:

ABHD8.DSEP07-UNSPLICED

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	8	73,980,611 - 73,981,111 (-)	MPROMDB

RGD ID:

6842599

Promoter ID:

MM_KWN:54782

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

NM_022419, UC009MDG.1

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	8	73,987,456 - 73,988,552 (-)	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1918946	AgrOrtholog
Ensembl Genes	ENSMUSG00000007950	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSMUSP00000008094	ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000008094	ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH	3.40.50.1820	UniProtKB/Swiss-Prot
InterPro	AB_hydrolase	UniProtKB/Swiss-Prot
	AB_hydrolase_1	UniProtKB/Swiss-Prot
	Epox_hydrolase-like	UniProtKB/Swiss-Prot
KEGG Report	mmu:64296	UniProtKB/Swiss-Prot
MGD	MGI:1918946	ENTREZGENE
NCBI Gene	64296	ENTREZGENE
Pfam	Abhydrolase_1	UniProtKB/Swiss-Prot
PhenoGen	Abhd8	PhenoGen
PRINTS	ABHYDROLASE	UniProtKB/Swiss-Prot
	EPOXHYDRLASE	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF53474	UniProtKB/Swiss-Prot
UniGene	Mm.276383	ENTREZGENE
UniProt	ABHD8_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary	Q9DC79	UniProtKB/Swiss-Prot
	Q9JMF5	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)