Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | C2CD5 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of C2CD5 mRNA | CTD | PMID:22079256 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | C2cd5 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of C2CD5 mRNA | CTD | PMID:33387578 | 4-hydroxyphenyl retinamide | decreases expression | EXP | | 6480464 | Fenretinide results in decreased expression of C2CD5 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | increases expression | ISO | C2cd5 (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of C2CD5 mRNA | CTD | PMID:30047161 | acetamide | increases expression | ISO | C2cd5 (Rattus norvegicus) | 6480464 | acetamide results in increased expression of C2CD5 mRNA | CTD | PMID:31881176 | all-trans-retinoic acid | decreases expression | ISO | C2CD5 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of C2CD5 mRNA | CTD | PMID:33167477 | amitrole | increases expression | ISO | C2cd5 (Rattus norvegicus) | 6480464 | Amitrole results in increased expression of C2CD5 mRNA | CTD | PMID:30047161 | antimycin A | decreases expression | ISO | C2CD5 (Homo sapiens) | 6480464 | Antimycin A results in decreased expression of C2CD5 mRNA | CTD | PMID:33512557 | aristolochic acid A | decreases expression | ISO | C2CD5 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of C2CD5 mRNA | CTD | PMID:33212167 | atrazine | decreases expression | ISO | C2CD5 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of C2CD5 mRNA | CTD | PMID:22378314 | atrazine | affects methylation | ISO | C2cd5 (Rattus norvegicus) | 6480464 | Atrazine affects the methylation of C2CD5 gene | CTD | PMID:28931070 | azoxystrobin | decreases expression | ISO | C2CD5 (Homo sapiens) | 6480464 | azoxystrobin results in decreased expression of C2CD5 mRNA | CTD | PMID:33512557 | benzo[a]pyrene | decreases expression | ISO | C2CD5 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of C2CD5 mRNA | CTD | PMID:20064835 | benzo[a]pyrene | increases methylation | EXP | | 6480464 | Benzo(a)pyrene results in increased methylation of C2CD5 intron | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | C2cd5 (Rattus norvegicus) | 6480464 | Benzo(a)pyrene results in increased expression of C2CD5 mRNA | CTD | PMID:21839799 | bisphenol A | decreases expression | ISO | C2cd5 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of C2CD5 mRNA | CTD | PMID:25181051 more ... | caffeine | increases expression | ISO | C2cd5 (Rattus norvegicus) | 6480464 | Caffeine results in increased expression of C2CD5 mRNA | CTD | PMID:20864626 | caffeine | affects phosphorylation | ISO | C2CD5 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of C2CD5 protein | CTD | PMID:35688186 | cobalt dichloride | decreases expression | ISO | C2cd5 (Rattus norvegicus) | 6480464 | cobaltous chloride results in decreased expression of C2CD5 mRNA | CTD | PMID:24386269 | copper(II) sulfate | decreases expression | ISO | C2CD5 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of C2CD5 mRNA | CTD | PMID:19549813 | coumarin | increases phosphorylation | ISO | C2CD5 (Homo sapiens) | 6480464 | coumarin results in increased phosphorylation of C2CD5 protein | CTD | PMID:35688186 | cyclosporin A | decreases expression | ISO | C2CD5 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of C2CD5 mRNA | CTD | PMID:20106945 and PMID:25562108 | deguelin | decreases expression | ISO | C2CD5 (Homo sapiens) | 6480464 | deguelin results in decreased expression of C2CD5 mRNA | CTD | PMID:33512557 | dicrotophos | decreases expression | ISO | C2CD5 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of C2CD5 mRNA | CTD | PMID:28302478 | elemental selenium | decreases expression | ISO | C2CD5 (Homo sapiens) | 6480464 | Selenium results in decreased expression of C2CD5 mRNA | CTD | PMID:19244175 | epoxiconazole | increases expression | EXP | | 6480464 | epoxiconazole results in increased expression of C2CD5 mRNA | CTD | PMID:35436446 | fenpyroximate | decreases expression | ISO | C2CD5 (Homo sapiens) | 6480464 | fenpyroximate results in decreased expression of C2CD5 mRNA | CTD | PMID:33512557 | flutamide | decreases expression | ISO | C2cd5 (Rattus norvegicus) | 6480464 | Flutamide results in decreased expression of C2CD5 mRNA | CTD | PMID:24793618 | FR900359 | affects phosphorylation | ISO | C2CD5 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of C2CD5 protein | CTD | PMID:37730182 | genistein | decreases expression | EXP | | 6480464 | Genistein results in decreased expression of C2CD5 mRNA | CTD | PMID:32186404 | hydrogen peroxide | affects expression | ISO | C2CD5 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of C2CD5 mRNA | CTD | PMID:20044591 | hydrogen peroxide | multiple interactions | ISO | C2CD5 (Homo sapiens) | 6480464 | [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of C2CD5 protein | CTD | PMID:18951874 | leflunomide | decreases expression | ISO | C2CD5 (Homo sapiens) | 6480464 | leflunomide results in decreased expression of C2CD5 mRNA | CTD | PMID:28988120 | maneb | multiple interactions | EXP | | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of C2CD5 mRNA | CTD | PMID:36117858 | menadione | affects expression | ISO | C2CD5 (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of C2CD5 mRNA | CTD | PMID:20044591 | methoxyacetic acid | increases expression | ISO | C2cd5 (Rattus norvegicus) | 6480464 | methoxyacetic acid results in increased expression of C2CD5 mRNA | CTD | PMID:20864626 | methylmercury chloride | increases expression | ISO | C2cd5 (Rattus norvegicus) | 6480464 | methylmercuric chloride results in increased expression of C2CD5 mRNA | CTD | PMID:20864626 | Monobutylphthalate | increases expression | ISO | C2cd5 (Rattus norvegicus) | 6480464 | monobutyl phthalate results in increased expression of C2CD5 mRNA | CTD | PMID:20864626 | nickel atom | decreases expression | ISO | C2CD5 (Homo sapiens) | 6480464 | Nickel results in decreased expression of C2CD5 mRNA | CTD | PMID:23195993 | oxaliplatin | multiple interactions | ISO | C2cd5 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of C2CD5 mRNA | CTD | PMID:25729387 | paracetamol | decreases expression | ISO | C2CD5 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of C2CD5 mRNA | CTD | PMID:21420995 and PMID:29067470 | paracetamol | decreases expression | ISO | C2cd5 (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of C2CD5 mRNA | CTD | PMID:33387578 | paraquat | multiple interactions | EXP | | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of C2CD5 mRNA | CTD | PMID:36117858 | picoxystrobin | decreases expression | ISO | C2CD5 (Homo sapiens) | 6480464 | picoxystrobin results in decreased expression of C2CD5 mRNA | CTD | PMID:33512557 | potassium chromate | multiple interactions | ISO | C2CD5 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of C2CD5 mRNA | CTD | PMID:22079256 | potassium chromate | decreases expression | ISO | C2CD5 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of C2CD5 mRNA | CTD | PMID:22079256 | pyrimidifen | decreases expression | ISO | C2CD5 (Homo sapiens) | 6480464 | pyrimidifen results in decreased expression of C2CD5 mRNA | CTD | PMID:33512557 | quercetin | decreases expression | ISO | C2CD5 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of C2CD5 mRNA | CTD | PMID:21632981 | quercetin | increases phosphorylation | ISO | C2CD5 (Homo sapiens) | 6480464 | Quercetin results in increased phosphorylation of C2CD5 protein | CTD | PMID:35688186 | selenium atom | decreases expression | ISO | C2CD5 (Homo sapiens) | 6480464 | Selenium results in decreased expression of C2CD5 mRNA | CTD | PMID:19244175 | silicon dioxide | decreases expression | ISO | C2CD5 (Homo sapiens) | 6480464 | Silicon Dioxide results in decreased expression of C2CD5 mRNA | CTD | PMID:25351596 | sulfadimethoxine | increases expression | ISO | C2cd5 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in increased expression of C2CD5 mRNA | CTD | PMID:30047161 | tebufenpyrad | decreases expression | ISO | C2CD5 (Homo sapiens) | 6480464 | 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in decreased expression of C2CD5 mRNA | CTD | PMID:33512557 | theophylline | multiple interactions | ISO | C2CD5 (Homo sapiens) | 6480464 | [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of C2CD5 protein | CTD | PMID:18951874 | thifluzamide | decreases expression | ISO | C2CD5 (Homo sapiens) | 6480464 | thifluzamide results in decreased expression of C2CD5 mRNA | CTD | PMID:33512557 | toluene | increases expression | ISO | C2cd5 (Rattus norvegicus) | 6480464 | Toluene results in increased expression of C2CD5 mRNA | CTD | PMID:22967744 | topotecan | multiple interactions | ISO | C2cd5 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of C2CD5 mRNA | CTD | PMID:25729387 | triptonide | decreases expression | EXP | | 6480464 | triptonide results in decreased expression of C2CD5 mRNA | CTD | PMID:33045310 | trovafloxacin | decreases expression | EXP | | 6480464 | trovafloxacin results in decreased expression of C2CD5 mRNA | CTD | PMID:35537566 | valproic acid | decreases methylation | ISO | C2CD5 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of C2CD5 gene | CTD | PMID:29154799 | valproic acid | decreases expression | ISO | C2CD5 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of C2CD5 mRNA | CTD | PMID:23179753 | valproic acid | affects splicing | ISO | C2cd5 (Rattus norvegicus) | 6480464 | Valproic Acid affects the splicing of C2CD5 mRNA | CTD | PMID:29427782 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
Cellular Component
Molecular Function
Phenotype Annotations Click to see Annotation Detail View
Mammalian Phenotype
Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Biological Process
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Cellular Component
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Molecular Function
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Phenotype Annotations
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Mammalian Phenotype
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | Functional annotation of a full-length mouse cDNA collection. | Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90. |
| 2. | MGDs mouse GO annotations | MGD data from the GO Consortium |
| 3. | Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. | Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73. |
| 4. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Additional References at PubMed
| PMID:8889548 | PMID:10349636 | PMID:10725249 | PMID:10922068 | PMID:11042159 | PMID:11076861 | PMID:11544199 | PMID:12477932 | PMID:12520002 | PMID:14610273 | PMID:15368895 | PMID:15489334 |
| PMID:15572359 | PMID:16141072 | PMID:16141073 | PMID:16919269 | PMID:17114649 | PMID:17967808 | PMID:18799693 | PMID:21267068 | PMID:21873635 | PMID:21907141 | PMID:21907143 | PMID:29378832 |
| PMID:31666192 | PMID:32325033 |
Genomics
Comparative Map Data
| C2cd5 (Mus musculus - house mouse) |
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| C2CD5 (Homo sapiens - human) |
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| C2cd5 (Rattus norvegicus - Norway rat) |
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| C2cd5 (Chinchilla lanigera - long-tailed chinchilla) |
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| C2CD5 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| C2CD5 (Canis lupus familiaris - dog) |
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| C2cd5 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| C2CD5 (Sus scrofa - pig) |
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| C2CD5 (Chlorocebus sabaeus - green monkey) |
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| C2cd5 (Heterocephalus glaber - naked mole-rat) |
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Variants
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Variants in C2cd5
3280 total Variants 
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