Higd2a (HIG1 hypoxia inducible domain family, member 2A) - Rat Genome Database

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Gene: Higd2a (HIG1 hypoxia inducible domain family, member 2A) Rattus norvegicus
Analyze
Symbol: Higd2a
Name: HIG1 hypoxia inducible domain family, member 2A
RGD ID: 1309691
Description: Predicted to be involved in mitochondrial respirasome assembly. Predicted to act upstream of or within negative regulation of apoptotic process. Predicted to be located in mitochondrial membrane. Predicted to be active in mitochondrion. Orthologous to several human genes including HIGD2A (HIG1 hypoxia inducible domain family member 2A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bis(2-ethylhexyl) phthalate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: HIG1 domain family member 2A, mitochondrial; HIG1 domain family, member 2A; LOC290999; RGD1309691; similar to RIKEN cDNA 2010110M21
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81710,026,961 - 10,027,885 (-)NCBIGRCr8
mRatBN7.21710,021,853 - 10,022,777 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1710,021,859 - 10,022,796 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1710,036,141 - 10,037,065 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01711,569,506 - 11,570,430 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01710,032,578 - 10,033,502 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01710,558,714 - 10,559,638 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1710,558,714 - 10,559,627 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01712,684,712 - 12,685,636 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41716,083,853 - 16,084,777 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1121,366,268 - 1,367,095 (+)NCBI
Celera1710,094,818 - 10,095,742 (-)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Higd2aRatEhlers-Danlos syndrome dermatosparaxis type  ISOHIGD2A (Homo sapiens)8554872ClinVar Annotator: match by term: Ehlers-Danlos syndrome and dermatosparaxis typeClinVarPMID:16770806 more ...
Higd2aRatSotos syndrome  ISOHIGD2A (Homo sapiens)8554872ClinVar Annotator: match by term: Sotos syndromeClinVarPMID:16770806 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Higd2aRatLiver Neoplasms  ISOHIGD2A (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:19233941
Higd2aRatpre-malignant neoplasm  ISOHIGD2A (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:19233941

1 to 20 of 45 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Higd2aRat1,2-dimethylhydrazine multiple interactionsISOHigd2a (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of HIGD2A mRNACTDPMID:22206623
Higd2aRat1,2-dimethylhydrazine decreases expressionISOHigd2a (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of HIGD2A mRNACTDPMID:22206623
Higd2aRat17beta-estradiol increases expressionISOHigd2a (Mus musculus)6480464Estradiol results in increased expression of HIGD2A mRNACTDPMID:39298647
Higd2aRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOHigd2a (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Lipopolysaccharides] results in decreased methylation of HIGD2A geneCTDPMID:21212295
Higd2aRat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of HIGD2A mRNACTDPMID:34747641
Higd2aRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOHigd2a (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of HIGD2A mRNACTDPMID:21570461 and PMID:24680724
Higd2aRat2-hydroxypropanoic acid affects expressionISOHIGD2A (Homo sapiens)6480464Lactic Acid affects the expression of HIGD2A mRNACTDPMID:30851411
Higd2aRat4,4'-sulfonyldiphenol increases expressionISOHigd2a (Mus musculus)6480464bisphenol S results in increased expression of HIGD2A mRNACTDPMID:39298647
Higd2aRataflatoxin B1 increases methylationISOHIGD2A (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of HIGD2A geneCTDPMID:27153756
Higd2aRatamphetamine increases expressionEXP 6480464Amphetamine results in increased expression of HIGD2A mRNACTDPMID:30779732
Higd2aRatarsenite(3-) multiple interactionsISOHIGD2A (Homo sapiens)6480464arsenite promotes the reaction [G3BP1 protein binds to HIGD2A mRNA]CTDPMID:32406909
Higd2aRatbenzo[b]fluoranthene increases expressionISOHigd2a (Mus musculus)6480464benzo(b)fluoranthene results in increased expression of HIGD2A mRNACTDPMID:26377693
Higd2aRatbis(2-ethylhexyl) phthalate multiple interactionsEXP 6480464[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of HIGD2A promoterCTDPMID:23359474
Higd2aRatbis(2-ethylhexyl) phthalate increases expressionISOHigd2a (Mus musculus)6480464Diethylhexyl Phthalate results in increased expression of HIGD2A mRNACTDPMID:33754040
Higd2aRatbisphenol A multiple interactionsEXP 6480464[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of HIGD2A promoterCTDPMID:23359474
Higd2aRatbisphenol A decreases expressionISOHigd2a (Mus musculus)6480464bisphenol A results in decreased expression of HIGD2A mRNACTDPMID:35598803
Higd2aRatbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of HIGD2A mRNACTDPMID:30816183 more ...
Higd2aRatbisphenol A affects expressionEXP 6480464bisphenol A affects the expression of HIGD2A mRNACTDPMID:25181051
Higd2aRatbuspirone increases expressionEXP 6480464Buspirone results in increased expression of HIGD2A mRNACTDPMID:24136188
Higd2aRatchloropicrin increases expressionISOHIGD2A (Homo sapiens)6480464chloropicrin results in increased expression of HIGD2A mRNACTDPMID:26352163

1 to 20 of 45 rows

Biological Process

  

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Higd2aRatmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Higd2aRatmitochondrial membrane located_inIEAUniProtKB-SubCell:SL-01711600115GO_REF:0000044UniProtGO_REF:0000044
Higd2aRatmitochondrion located_inISOHIGD2A (Homo sapiens)9068941 PMID:34800366FlyBasePMID:34800366
Higd2aRatmitochondrion is_active_inIBAMGI:1930666 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Higd2aRatmitochondrion is_active_inISOHigd2a (Mus musculus)1624291 PMID:32085461RGDPMID:32085461
Higd2aRatnucleus is_active_inISOHigd2a (Mus musculus)1624291 PMID:32085461RGDPMID:32085461


#
Reference Title
Reference Citation
1. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:12477932   PMID:18614015   PMID:21856340   PMID:22405070   PMID:34800366  



Higd2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81710,026,961 - 10,027,885 (-)NCBIGRCr8
mRatBN7.21710,021,853 - 10,022,777 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1710,021,859 - 10,022,796 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1710,036,141 - 10,037,065 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01711,569,506 - 11,570,430 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01710,032,578 - 10,033,502 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01710,558,714 - 10,559,638 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1710,558,714 - 10,559,627 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01712,684,712 - 12,685,636 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41716,083,853 - 16,084,777 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1121,366,268 - 1,367,095 (+)NCBI
Celera1710,094,818 - 10,095,742 (-)NCBICelera
Cytogenetic Map17p14NCBI
HIGD2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385176,388,751 - 176,389,761 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5176,388,751 - 176,389,761 (+)EnsemblGRCh38hg38GRCh38
GRCh375175,815,752 - 175,816,762 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365175,748,390 - 175,749,357 (+)NCBINCBI36Build 36hg18NCBI36
Celera5172,685,350 - 172,686,317 (-)NCBICelera
Cytogenetic Map5q35.2NCBI
HuRef5170,740,347 - 170,741,314 (+)NCBIHuRef
CHM1_15175,248,732 - 175,249,699 (+)NCBICHM1_1
T2T-CHM13v2.05176,933,109 - 176,934,119 (+)NCBIT2T-CHM13v2.0
Higd2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391354,738,044 - 54,738,960 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1354,738,020 - 54,738,971 (+)EnsemblGRCm39 Ensembl
GRCm381354,590,231 - 54,591,147 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1354,590,207 - 54,591,158 (+)EnsemblGRCm38mm10GRCm38
MGSCv371354,691,592 - 54,692,508 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361354,599,853 - 54,600,769 (+)NCBIMGSCv36mm8
Celera1355,656,607 - 55,657,523 (+)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1328.84NCBI
Higd2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540828,689,781 - 28,690,762 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540828,689,781 - 28,690,762 (+)NCBIChiLan1.0ChiLan1.0
HIGD2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24171,467,897 - 171,468,839 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15169,607,436 - 169,608,382 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05171,685,512 - 171,686,527 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15178,757,440 - 178,758,686 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5178,757,667 - 178,758,676 (+)Ensemblpanpan1.1panPan2
HIGD2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1436,937,441 - 36,938,436 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha436,904,973 - 36,905,973 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0437,305,086 - 37,306,087 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl437,304,239 - 37,306,035 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1437,130,372 - 37,131,372 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0437,317,956 - 37,318,957 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0437,826,978 - 37,827,978 (-)NCBIUU_Cfam_GSD_1.0
Higd2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213121,636,820 - 121,638,117 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936597661,740 - 662,752 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HIGD2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl281,486,890 - 81,488,045 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1281,486,890 - 81,488,039 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2283,138,547 - 83,139,696 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HIGD2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12378,392,364 - 78,393,407 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660759,521,048 - 9,522,056 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Higd2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473313,740,949 - 13,741,915 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473313,740,949 - 13,741,927 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Higd2a
5 total Variants

Predicted Target Of
Summary Value
Count of predictions:42
Count of miRNA genes:38
Interacting mature miRNAs:41
Transcripts:ENSRNOT00000023515
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 31 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17999128640540197Rat
631499Stl1Serum triglyceride level QTL 13.6blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)17327139827389946Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17435448727028127Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17211514934551001Rat
1582224Epfw4Epididymal fat weight QTL 43.50.0058epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)17920136523653323Rat
1582225Bw67Body weight QTL 676.20.0001body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582226Bw64Body weight QTL 644.20.0017body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131701463Rat

1 to 10 of 31 rows
RH133064  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2122,777,024 - 2,777,234 (-)MAPPERmRatBN7.2
mRatBN7.21710,021,906 - 10,022,116 (+)MAPPERmRatBN7.2
Rnor_6.01710,558,768 - 10,558,977NCBIRnor6.0
Rnor_6.0124,546,604 - 4,546,813NCBIRnor6.0
Rnor_5.01712,684,766 - 12,684,975UniSTSRnor5.0
Rnor_5.0126,674,667 - 6,674,876UniSTSRnor5.0
RGSC_v3.41716,083,907 - 16,084,116UniSTSRGSC3.4
RGSC_v3.4121,366,613 - 1,366,822UniSTSRGSC3.4
Celera124,592,000 - 4,592,209UniSTS
Celera1710,094,872 - 10,095,081UniSTS
Cytogenetic Map12p12UniSTS
Cytogenetic Map17p14UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000023515   ⟹   ENSRNOP00000023515
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1710,021,859 - 10,022,796 (-)Ensembl
Rnor_6.0 Ensembl1710,558,714 - 10,559,627 (-)Ensembl
RefSeq Acc Id: NM_001106102   ⟹   NP_001099572
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81710,026,961 - 10,027,885 (-)NCBI
mRatBN7.21710,021,853 - 10,022,777 (-)NCBI
Rnor_6.01710,558,714 - 10,559,638 (-)NCBI
Rnor_5.01712,684,712 - 12,685,636 (-)NCBI
RGSC_v3.41716,083,853 - 16,084,777 (-)RGD
Celera1710,094,818 - 10,095,742 (-)RGD
Sequence:
Protein RefSeqs NP_001099572 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI66544 (Get FASTA)   NCBI Sequence Viewer  
  EDL94039 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000023515
  ENSRNOP00000023515.3
RefSeq Acc Id: NP_001099572   ⟸   NM_001106102
- UniProtKB: B2GV65 (UniProtKB/TrEMBL),   F7FGX2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000023515   ⟸   ENSRNOT00000023515
HIG1


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13700323
Promoter ID:EPDNEW_R10845
Type:multiple initiation site
Name:Higd2a_1
Description:HIG1 hypoxia inducible domain family, member 2A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01710,559,622 - 10,559,682EPDNEW


1 to 19 of 19 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-10175 BioCyc
Ensembl Genes ENSRNOG00000017372 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000023515 ENTREZGENE
  ENSRNOT00000023515.7 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.1320 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7301761 IMAGE-MGC_LOAD
InterPro Hypoxia_induced_prot_cons-reg UniProtKB/TrEMBL
  RCF1 UniProtKB/TrEMBL
KEGG Report rno:290999 UniProtKB/TrEMBL
MGC_CLONE MGC:188144 IMAGE-MGC_LOAD
NCBI Gene 290999 ENTREZGENE
PANTHER HIG1 DOMAIN FAMILY MEMBER 2A UniProtKB/TrEMBL
  HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED UniProtKB/TrEMBL
Pfam HIG_1_N UniProtKB/TrEMBL
PhenoGen Higd2a PhenoGen
PROSITE HIG1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000017372 RatGTEx
UniProt B2GV65 ENTREZGENE, UniProtKB/TrEMBL
  F7FGX2 ENTREZGENE, UniProtKB/TrEMBL
1 to 19 of 19 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-05-18 Higd2a  HIG1 hypoxia inducible domain family, member 2A  Higd2a  HIG1 domain family, member 2A   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Higd2a  HIG1 domain family, member 2A   Higd2a_predicted  HIG1 domain family, member 2A (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Higd2a_predicted  HIG1 domain family, member 2A (predicted)  RGD1309691_predicted  similar to RIKEN cDNA 2010110M21 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1309691_predicted  similar to RIKEN cDNA 2010110M21 (predicted)  LOC290999_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC290999_predicted  similar to RIKEN cDNA 2010110M21 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL