Glyr1 (glyoxylate reductase 1 homolog) - Rat Genome Database

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Gene: Glyr1 (glyoxylate reductase 1 homolog) Ictidomys tridecemlineatus
Analyze
Symbol: Glyr1
Name: glyoxylate reductase 1 homolog
RGD ID: 12698702
Description: ENCODES a protein that exhibits chromatin binding (inferred); chromatin-protein adaptor activity (inferred); DNA binding (inferred); INVOLVED IN transcription elongation-coupled chromatin remodeling (inferred); transcription initiation-coupled chromatin remodeling (inferred); ASSOCIATED WITH atrioventricular septal defect (ortholog); Rubinstein-Taybi syndrome (ortholog); FOUND IN chromatin (inferred); chromosome (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: putative oxidoreductase GLYR1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344106,916,484 - 106,948,692 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365304,761,823 - 4,794,729 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365304,761,838 - 4,794,191 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Glyr1SquirrelRubinstein-Taybi syndrome  ISOGLYR1 (Homo sapiens)8554872ClinVar Annotator: match by term: Rubinstein-Taybi syndromeClinVarPMID:18688873 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Glyr1Squirrelatrioventricular septal defect  ISOGlyr1 (Mus musculus)9068941OMIM:600309 more ...MouseDO 


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Glyr1Squirreltranscription elongation-coupled chromatin remodeling involved_inIEAUniProtKB:Q49A26 and ensembl:ENSP00000322716150520179 EnsemblGO_REF:0000107
Glyr1Squirreltranscription elongation-coupled chromatin remodeling involved_inIEAPANTHER:PTN000541405150520179 TreeGrafterGO_REF:0000118
Glyr1Squirreltranscription initiation-coupled chromatin remodeling involved_inIEAUniProtKB:Q49A26 and ensembl:ENSP00000322716150520179 EnsemblGO_REF:0000107

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Glyr1Squirrelchromatin located_inIEAPANTHER:PTN000541405150520179 TreeGrafterGO_REF:0000118
Glyr1Squirrelchromatin is_active_inIEAUniProtKB:Q49A26 and ensembl:ENSP00000322716150520179 EnsemblGO_REF:0000107
Glyr1Squirrelchromosome located_inIEAUniProtKB-SubCell:SL-0468150520179 UniProtGO_REF:0000044
Glyr1Squirrelchromosome located_inIEAUniProtKB-KW:KW-0158150520179 UniProtGO_REF:0000043
Glyr1Squirrelcytosol located_inIEAUniProtKB:Q49A26 and ensembl:ENSP00000322716150520179 EnsemblGO_REF:0000107
Glyr1Squirrelnucleoplasm located_inIEAUniProtKB:Q49A26 and ensembl:ENSP00000322716150520179 EnsemblGO_REF:0000107
Glyr1Squirrelnucleosome part_ofIEAUniProtKB:Q49A26 and ensembl:ENSP00000322716150520179 EnsemblGO_REF:0000107

Molecular Function
1 to 15 of 15 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Glyr1Squirrelchromatin binding enablesIEAUniProtKB:Q49A26 and ensembl:ENSP00000322716150520179 EnsemblGO_REF:0000107
Glyr1Squirrelchromatin-protein adaptor activity enablesIEAUniProtKB:Q49A26 and ensembl:ENSP00000322716150520179 EnsemblGO_REF:0000107
Glyr1SquirrelDNA binding enablesIEAUniProtKB:Q49A26 and ensembl:ENSP00000322716150520179 EnsemblGO_REF:0000107
Glyr1SquirrelDNA binding enablesIEAPANTHER:PTN000541405150520179 TreeGrafterGO_REF:0000118
Glyr1Squirrelhistone binding enablesIEAUniProtKB:Q49A26 and ensembl:ENSP00000322716150520179 EnsemblGO_REF:0000107
Glyr1SquirrelNAD binding enablesIEAInterPro:IPR029154150520179 InterProGO_REF:0000002
Glyr1SquirrelNADP binding enablesIEAInterPro:IPR006115150520179 InterProGO_REF:0000002
Glyr1Squirrelnucleosome binding enablesIEAUniProtKB:Q49A26 and ensembl:ENSP00000322716150520179 EnsemblGO_REF:0000107
Glyr1Squirrelnucleosome binding enablesIEAPANTHER:PTN000541405150520179 TreeGrafterGO_REF:0000118
Glyr1Squirrelprotein binding enablesISOUniProtKB:Q8NB789068941 PMID:23260659UniProtPMID:23260659
Glyr1Squirrelprotein binding enablesISOUniProtKB:P436949068941 PMID:35182466UniProtPMID:35182466
Glyr1Squirrelprotein binding enablesISOUniProtKB:Q14192 and UniProtKB:Q8N9N89068941 PMID:31515488IntActPMID:31515488
Glyr1Squirrelprotein binding enablesISOUniProtKB:O95833 more ...9068941 PMID:32296183IntActPMID:32296183
Glyr1Squirrelprotein binding enablesISOUniProtKB:O00291 more ...9068941 PMID:32814053IntActPMID:32814053
Glyr1Squirrelprotein binding enablesISOUniProtKB:P24863 more ...9068941 PMID:25416956IntActPMID:25416956
1 to 15 of 15 rows

PMID:22301074   PMID:30032202  



Glyr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344106,916,484 - 106,948,692 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365304,761,823 - 4,794,729 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365304,761,838 - 4,794,191 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GLYR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38164,803,203 - 4,847,288 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl164,803,203 - 4,847,288 (-)EnsemblGRCh38hg38GRCh38
GRCh37164,853,204 - 4,897,289 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36164,793,205 - 4,837,285 (-)NCBINCBI36Build 36hg18NCBI36
Celera165,061,974 - 5,106,076 (-)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef164,819,402 - 4,863,584 (-)NCBIHuRef
CHM1_1164,854,050 - 4,898,201 (-)NCBICHM1_1
T2T-CHM13v2.0164,832,757 - 4,876,778 (-)NCBIT2T-CHM13v2.0
Glyr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39164,831,766 - 4,867,780 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl164,831,773 - 4,867,727 (-)EnsemblGRCm39 Ensembl
GRCm38165,013,902 - 5,049,938 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl165,013,909 - 5,049,863 (-)EnsemblGRCm38mm10GRCm38
MGSCv37165,013,995 - 5,050,003 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36164,929,258 - 4,965,170 (-)NCBIMGSCv36mm8
Celera165,645,276 - 5,681,247 (-)NCBICelera
Cytogenetic Map16A1NCBI
cM Map162.49NCBI
Glyr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81011,038,577 - 11,074,093 (+)NCBIGRCr8
mRatBN7.21010,532,036 - 10,567,639 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1010,532,154 - 10,567,637 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1015,240,171 - 15,273,873 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01014,728,991 - 14,762,692 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01010,398,277 - 10,431,933 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01010,725,830 - 10,759,471 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1010,725,819 - 10,761,279 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0109,492,794 - 9,528,295 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41010,648,082 - 10,681,723 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11010,648,081 - 10,681,723 (+)NCBI
Celera109,495,963 - 9,529,604 (+)NCBICelera
Cytogenetic Map10q12NCBI
Glyr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544212,654,805 - 12,694,090 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544212,654,805 - 12,694,090 (+)NCBIChiLan1.0ChiLan1.0
GLYR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2185,331,400 - 5,375,699 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1169,121,553 - 9,165,856 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0163,727,358 - 3,771,554 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1164,892,827 - 4,936,615 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl164,892,827 - 4,936,615 (-)Ensemblpanpan1.1panPan2
GLYR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1636,582,438 - 36,618,265 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl636,582,461 - 36,616,206 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha637,974,709 - 38,010,518 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0636,785,395 - 36,821,238 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl636,785,359 - 36,821,238 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1636,579,988 - 36,615,294 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0636,472,906 - 36,508,177 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0636,874,580 - 36,910,393 (+)NCBIUU_Cfam_GSD_1.0
GLYR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl337,555,394 - 37,593,559 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1337,555,357 - 37,593,492 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2338,626,413 - 38,664,624 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GLYR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.154,473,222 - 4,518,150 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl54,475,227 - 4,518,071 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606826,140,241 - 26,186,300 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Glyr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248242,655,909 - 2,692,522 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248242,655,909 - 2,692,546 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.






Ensembl Acc Id: ENSSTOT00000012330   ⟹   ENSSTOP00000011049
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365304,763,866 - 4,794,162 (-)Ensembl
Ensembl Acc Id: ENSSTOT00000033437   ⟹   ENSSTOP00000026969
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365304,761,823 - 4,794,729 (-)Ensembl
RefSeq Acc Id: XM_005327147   ⟹   XP_005327204
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344106,916,484 - 106,948,691 (-)NCBI
SpeTri2.0NW_0049365304,763,145 - 4,794,185 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021727625   ⟹   XP_021583300
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344106,916,484 - 106,948,691 (-)NCBI
SpeTri2.0NW_0049365304,761,838 - 4,794,184 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021727626   ⟹   XP_021583301
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344106,918,003 - 106,948,692 (-)NCBI
SpeTri2.0NW_0049365304,763,145 - 4,794,185 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021727627   ⟹   XP_021583302
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344106,918,003 - 106,948,692 (-)NCBI
SpeTri2.0NW_0049365304,763,145 - 4,794,187 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021727628   ⟹   XP_021583303
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344106,916,484 - 106,948,692 (-)NCBI
SpeTri2.0NW_0049365304,763,145 - 4,794,190 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021727629   ⟹   XP_021583304
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344106,916,484 - 106,948,692 (-)NCBI
SpeTri2.0NW_0049365304,763,145 - 4,794,191 (-)NCBI
Sequence:
RefSeq Acc Id: XP_005327204   ⟸   XM_005327147
- Peptide Label: isoform X2
- UniProtKB: I3MIY4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021583300   ⟸   XM_021727625
- Peptide Label: isoform X1
- UniProtKB: A0A287D0E9 (UniProtKB/TrEMBL),   I3MIY4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021583304   ⟸   XM_021727629
- Peptide Label: isoform X6
- UniProtKB: I3MIY4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021583303   ⟸   XM_021727628
- Peptide Label: isoform X5
- UniProtKB: I3MIY4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021583302   ⟸   XM_021727627
- Peptide Label: isoform X4
- UniProtKB: I3MIY4 (UniProtKB/TrEMBL)
- Sequence:
PWWP



1 to 27 of 27 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSSTOG00000012326 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000012330.3 UniProtKB/TrEMBL
  ENSSTOT00000033437.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.30.140 UniProtKB/TrEMBL
  N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2 UniProtKB/TrEMBL
  NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro 6-PGluconate_DH-like_C_sf UniProtKB/TrEMBL
  6PGD_dom2 UniProtKB/TrEMBL
  6PGDH_NADP-bd UniProtKB/TrEMBL
  HIBADH-related_NP60_sf UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  NADP-bd UniProtKB/TrEMBL
  NP60_PWWP UniProtKB/TrEMBL
  PWWP_dom UniProtKB/TrEMBL
NCBI Gene Glyr1 ENTREZGENE
PANTHER OXIDOREDUCTASE GLYR1-RELATED UniProtKB/TrEMBL
  OXIDOREDUCTASE GLYR1-RELATED UniProtKB/TrEMBL
Pfam NAD_binding_11 UniProtKB/TrEMBL
  NAD_binding_2 UniProtKB/TrEMBL
  PWWP UniProtKB/TrEMBL
PROSITE PWWP UniProtKB/TrEMBL
SMART PWWP UniProtKB/TrEMBL
Superfamily-SCOP SSF48179 UniProtKB/TrEMBL
  SSF51735 UniProtKB/TrEMBL
  Tudor/PWWP/MBT UniProtKB/TrEMBL
UniProt A0A287D0E9 ENTREZGENE, UniProtKB/TrEMBL
  I3MIY4 ENTREZGENE, UniProtKB/TrEMBL
1 to 27 of 27 rows