Nup85 (nucleoporin 85) - Rat Genome Database

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Gene: Nup85 (nucleoporin 85) Ictidomys tridecemlineatus
Analyze
Symbol: Nup85
Name: nucleoporin 85
RGD ID: 12694883
Description: ENCODES a protein that exhibits structural constituent of nuclear pore (inferred); INVOLVED IN chemotaxis (inferred); lamellipodium assembly (inferred); macrophage chemotaxis (inferred); PARTICIPATES IN mRNA nuclear export pathway; ASSOCIATED WITH nephrotic syndrome type 17 (ortholog); FOUND IN actin cytoskeleton (inferred); ciliary basal body (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: nuclear pore complex protein Nup85; nucleoporin 85, transcript variant X1; nucleoporin 85, transcript variant X2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056025,880,087 - 5,908,344 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936594503,720 - 531,875 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936594503,698 - 531,851 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nup85Squirrelnephrotic syndrome type 17  ISONUP85 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nup85Squirrelnephrotic syndrome type 17  ISONUP85 (Homo sapiens)7240710 OMIM 


Biological Process
1 to 9 of 9 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nup85Squirrelchemotaxis acts_upstream_of_or_withinIEAUniProtKB:Q8R480 and ensembl:ENSMUSP00000021085150520179 EnsemblGO_REF:0000107
Nup85Squirrellamellipodium assembly acts_upstream_of_or_withinIEAUniProtKB:Q8R480 and ensembl:ENSMUSP00000021085150520179 EnsemblGO_REF:0000107
Nup85Squirrelmacrophage chemotaxis acts_upstream_of_or_withinIEAUniProtKB:Q8R480 and ensembl:ENSMUSP00000021085150520179 EnsemblGO_REF:0000107
Nup85SquirrelmRNA export from nucleus involved_inIEAPANTHER:PTN000332535150520179 TreeGrafterGO_REF:0000118
Nup85SquirrelmRNA transport involved_inIEAUniProtKB-KW:KW-0509150520179 UniProtGO_REF:0000043
Nup85Squirrelnephron development involved_inIEAUniProtKB:Q9BW27 and ensembl:ENSP00000245544150520179 EnsemblGO_REF:0000107
Nup85Squirrelpositive regulation of DNA-templated transcription involved_inIEAPANTHER:PTN000332535150520179 TreeGrafterGO_REF:0000118
Nup85Squirrelprotein import into nucleus involved_inIEAPANTHER:PTN000332535150520179 TreeGrafterGO_REF:0000118
Nup85Squirrelprotein transport involved_inIEAUniProtKB-KW:KW-0653 and UniProtKB-KW:KW-0811150520179 UniProtGO_REF:0000043
1 to 9 of 9 rows

Cellular Component
1 to 14 of 14 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nup85Squirrelactin cytoskeleton located_inIEAUniProtKB:Q9BW27 and ensembl:ENSP00000245544150520179 EnsemblGO_REF:0000107
Nup85Squirrelciliary basal body located_inIEAUniProtKB:Q9BW27 and ensembl:ENSP00000245544150520179 EnsemblGO_REF:0000107
Nup85Squirrelcytosol located_inIEAUniProtKB:Q9BW27 and ensembl:ENSP00000245544150520179 EnsemblGO_REF:0000107
Nup85Squirrelintracellular membrane-bounded organelle located_inIEAUniProtKB:Q9BW27 and ensembl:ENSP00000245544150520179 EnsemblGO_REF:0000107
Nup85Squirrelkinetochore located_inIEAUniProtKB:Q9BW27 and ensembl:ENSP00000245544150520179 EnsemblGO_REF:0000107
Nup85Squirrelmembrane located_inIEAUniProtKB-KW:KW-0472150520179 UniProtGO_REF:0000043
Nup85Squirrelnuclear envelope located_inIEAUniProtKB:Q9BW27 and ensembl:ENSP00000245544150520179 EnsemblGO_REF:0000107
Nup85Squirrelnuclear membrane located_inIEAUniRule:UR000995752150520179 UniProtGO_REF:0000104
Nup85Squirrelnuclear pore part_ofIEAUniProtKB-KW:KW-0906150520179 UniProtGO_REF:0000043
Nup85Squirrelnuclear pore part_ofIEAUniProtKB-SubCell:SL-0185150520179 UniProtGO_REF:0000044
Nup85Squirrelnuclear pore outer ring part_ofIEAPANTHER:PTN000332535150520179 TreeGrafterGO_REF:0000118
Nup85Squirrelnuclear pore outer ring part_ofIEAUniProtKB:Q9BW27 and ensembl:ENSP00000245544150520179 EnsemblGO_REF:0000107
Nup85Squirrelnucleoplasm located_inIEAUniProtKB:Q9BW27 and ensembl:ENSP00000245544150520179 EnsemblGO_REF:0000107
Nup85Squirrelnucleus located_inIEAUniProtKB-KW:KW-0539150520179 UniProtGO_REF:0000043
1 to 14 of 14 rows

Molecular Function

  

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nup85SquirrelmRNA nuclear export pathway   ISONUP85 (Homo sapiens)9068941 RGDPMID:25184662 and REF_RGD_ID:9743947
PMID:30032202  



Nup85
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056025,880,087 - 5,908,344 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936594503,720 - 531,875 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936594503,698 - 531,851 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NUP85
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381775,205,679 - 75,235,758 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1775,205,659 - 75,235,758 (+)EnsemblGRCh38hg38GRCh38
GRCh371773,201,774 - 73,231,853 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361770,713,192 - 70,743,449 (+)NCBINCBI36Build 36hg18NCBI36
Build 341770,713,380 - 70,743,447NCBI
Celera1769,793,975 - 69,824,185 (+)NCBICelera
Cytogenetic Map17q25.1NCBI
HuRef1768,611,339 - 68,641,549 (+)NCBIHuRef
CHM1_11773,266,184 - 73,296,417 (+)NCBICHM1_1
T2T-CHM13v2.01776,097,807 - 76,127,836 (+)NCBIT2T-CHM13v2.0
Nup85
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911115,455,264 - 115,474,750 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11115,455,260 - 115,474,811 (+)EnsemblGRCm39 Ensembl
GRCm3811115,564,432 - 115,583,924 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11115,564,434 - 115,583,985 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711115,425,758 - 115,445,226 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611115,380,572 - 115,400,075 (+)NCBIMGSCv36mm8
Celera11127,337,030 - 127,351,679 (+)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1180.87NCBI
Nup85
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810101,305,241 - 101,323,980 (+)NCBIGRCr8
mRatBN7.210100,806,482 - 100,825,029 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10100,806,437 - 100,825,043 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10105,866,595 - 105,885,241 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010105,329,668 - 105,348,314 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010100,727,451 - 100,746,001 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010104,118,999 - 104,137,258 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10104,118,945 - 104,137,319 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010104,144,378 - 104,162,637 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410105,645,505 - 105,665,079 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110105,660,008 - 105,679,580 (+)NCBI
Celera1099,381,083 - 99,399,472 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
Nup85
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555532,079,503 - 2,107,807 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555532,079,418 - 2,107,894 (+)NCBIChiLan1.0ChiLan1.0
NUP85
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21991,243,861 - 91,275,146 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11796,067,989 - 96,098,214 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01769,152,452 - 69,182,688 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11774,715,056 - 74,735,706 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1774,708,654 - 74,735,628 (+)Ensemblpanpan1.1panPan2
NUP85
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.195,251,387 - 5,298,096 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl95,251,419 - 5,285,338 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha95,930,369 - 5,977,004 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.095,921,442 - 5,968,402 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl95,921,442 - 5,968,410 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.195,960,174 - 6,006,787 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.096,070,418 - 6,117,068 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.096,130,422 - 6,177,075 (-)NCBIUU_Cfam_GSD_1.0
NUP85
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl126,071,812 - 6,103,979 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1126,072,731 - 6,103,972 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2126,035,178 - 6,066,433 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NUP85
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11646,433,821 - 46,463,822 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1646,433,579 - 46,463,759 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607717,203,748 - 17,236,457 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nup85
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248015,022,617 - 5,057,140 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248015,023,255 - 5,057,140 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.






Ensembl Acc Id: ENSSTOT00000015180   ⟹   ENSSTOP00000013601
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936594503,720 - 531,875 (+)Ensembl
RefSeq Acc Id: XM_005332549   ⟹   XP_005332606
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244056025,880,087 - 5,908,344 (-)NCBI
SpeTri2.0NW_004936594503,698 - 531,851 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040268470   ⟹   XP_040124404
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244056025,880,087 - 5,907,990 (-)NCBI
RefSeq Acc Id: XM_040268471   ⟹   XP_040124405
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244056025,880,087 - 5,908,135 (-)NCBI
Protein RefSeqs XP_005332606 (Get FASTA)   NCBI Sequence Viewer  
  XP_040124404 (Get FASTA)   NCBI Sequence Viewer  
  XP_040124405 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000013601.2
GenBank Protein KAG3268525 (Get FASTA)   NCBI Sequence Viewer  
  KAG3268526 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005332606   ⟸   XM_005332549
- Peptide Label: isoform X1
- UniProtKB: I3MPA7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040124405   ⟸   XM_040268471
- Peptide Label: isoform X2
RefSeq Acc Id: XP_040124404   ⟸   XM_040268470
- Peptide Label: isoform X2
Ensembl Acc Id: ENSSTOP00000013601   ⟸   ENSSTOT00000015180



Database
Acc Id
Source(s)
Ensembl Genes ENSSTOG00000015175 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000015180.3 UniProtKB/TrEMBL
InterPro Nucleoporin_Nup85 UniProtKB/TrEMBL
NCBI Gene Nup85 ENTREZGENE
PANTHER NUCLEAR PORE COMPLEX PROTEIN NUP85 UniProtKB/TrEMBL
  PTHR13373 UniProtKB/TrEMBL
Pfam Nucleopor_Nup85 UniProtKB/TrEMBL
UniProt I3MPA7 ENTREZGENE, UniProtKB/TrEMBL