Asf1a (anti-silencing function 1A histone chaperone) - Rat Genome Database

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Gene: Asf1a (anti-silencing function 1A histone chaperone) Ictidomys tridecemlineatus
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Symbol: Asf1a
Name: anti-silencing function 1A histone chaperone
RGD ID: 12659171
Description: ENCODES a protein that exhibits chromatin binding (inferred); histone binding (inferred); histone chaperone activity (inferred); INVOLVED IN DNA repair (ortholog); muscle cell differentiation (ortholog); nucleosome assembly (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH autistic disorder (ortholog); congenital disorder of glycosylation Iaa (ortholog); epilepsy (ortholog); FOUND IN site of double-strand break (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: histone chaperone ASF1A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946109,592,255 - 109,606,875 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366581,699,044 - 1,715,582 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366581,699,150 - 1,713,079 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Asf1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946109,592,255 - 109,606,875 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366581,699,044 - 1,715,582 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366581,699,150 - 1,713,079 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ASF1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386118,894,152 - 118,909,171 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6118,894,152 - 118,909,171 (+)EnsemblGRCh38hg38GRCh38
GRCh376119,215,316 - 119,230,336 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366119,263,628 - 119,272,035 (+)NCBINCBI36Build 36hg18NCBI36
Build 346119,263,627 - 119,272,029NCBI
Celera6119,959,803 - 119,974,994 (+)NCBICelera
Cytogenetic Map6q22.31NCBI
HuRef6116,797,372 - 116,812,467 (+)NCBIHuRef
CHM1_16119,479,284 - 119,494,377 (+)NCBICHM1_1
T2T-CHM13v2.06120,079,995 - 120,095,013 (+)NCBIT2T-CHM13v2.0
Asf1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391053,473,057 - 53,485,321 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1053,472,853 - 53,485,321 (+)EnsemblGRCm39 Ensembl
GRCm381053,596,961 - 53,609,225 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1053,596,757 - 53,609,225 (+)EnsemblGRCm38mm10GRCm38
MGSCv371053,316,767 - 53,329,031 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361053,285,376 - 53,297,640 (+)NCBIMGSCv36mm8
Celera1054,424,436 - 54,436,700 (+)NCBICelera
Cytogenetic Map10B3NCBI
cM Map1027.24NCBI
Asf1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82033,436,632 - 33,451,478 (+)NCBIGRCr8
mRatBN7.22032,893,962 - 32,908,808 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2032,893,573 - 32,908,808 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2033,933,507 - 33,948,491 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02033,324,220 - 33,339,204 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02034,051,143 - 34,066,130 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02034,894,419 - 34,909,265 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2034,894,419 - 34,909,265 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02036,651,864 - 36,666,710 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42032,261,624 - 32,276,470 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12032,242,606 - 32,288,661 (+)NCBI
Celera2034,286,255 - 34,301,101 (+)NCBICelera
Cytogenetic Map20q11NCBI
Asf1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554361,635,399 - 1,645,075 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554361,635,397 - 1,640,989 (+)NCBIChiLan1.0ChiLan1.0
ASF1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25138,907,808 - 138,923,010 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16136,805,190 - 136,818,669 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06116,702,314 - 116,717,445 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16120,843,523 - 120,858,477 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6120,843,461 - 120,858,471 (+)Ensemblpanpan1.1panPan2
ASF1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1158,821,324 - 58,834,935 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl158,821,521 - 58,946,475 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha159,624,039 - 59,637,812 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0159,005,923 - 59,019,731 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl159,006,146 - 59,024,788 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1158,906,233 - 58,920,041 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0158,747,902 - 58,761,670 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0159,379,406 - 59,393,234 (+)NCBIUU_Cfam_GSD_1.0
ASF1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl143,200,415 - 43,214,913 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1143,200,339 - 43,215,019 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2148,350,741 - 48,365,279 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ASF1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11354,972,514 - 54,988,436 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1354,969,299 - 54,988,558 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604027,296,097 - 27,311,554 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Asf1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462479811,306,849 - 11,317,075 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005336093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSSTOT00000027562   ⟹   ENSSTOP00000019890
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366581,699,044 - 1,715,582 (+)Ensembl
RefSeq Acc Id: XM_005336093   ⟹   XP_005336150
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404946109,592,255 - 109,606,875 (+)NCBI
SpeTri2.0NW_0049366581,699,150 - 1,713,079 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005336150 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000019890.1
GenBank Protein KAG3290137 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005336150   ⟸   XM_005336093
- UniProtKB: I3N694 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSTOP00000019890   ⟸   ENSSTOT00000027562


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000027796 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000027562.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.1490 UniProtKB/TrEMBL
InterPro ASF1-like UniProtKB/TrEMBL
  ASF1-like_sf UniProtKB/TrEMBL
NCBI Gene Asf1a ENTREZGENE
PANTHER HISTONE CHAPERONE ASF1A UniProtKB/TrEMBL
  PTHR12040 UniProtKB/TrEMBL
Pfam ASF1_hist_chap UniProtKB/TrEMBL
Superfamily-SCOP SSF101546 UniProtKB/TrEMBL
UniProt I3N694 ENTREZGENE, UniProtKB/TrEMBL