Aen (apoptosis enhancing nuclease)

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Gene: Aen (apoptosis enhancing nuclease) Ictidomys tridecemlineatus

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Symbol:

Aen

Name:

apoptosis enhancing nuclease

RGD ID:

12639921

Description:

ENCODES a protein that exhibits DNA exonuclease activity (ortholog); INVOLVED IN response to ionizing radiation (ortholog); ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN nuclear membrane (ortholog); nucleolus (ortholog); nucleoplasm (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

apoptosis enhancing nuclease, transcript variant X1; apoptosis enhancing nuclease, transcript variant X2; apoptosis enhancing nuclease, transcript variant X3; apoptosis-enhancing nuclease

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	131,722,868 - 131,745,835 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936483	14,601,671 - 14,611,613 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Bloom syndrome (ISO)

colorectal cancer (ISO)

Experimental Liver Cirrhosis (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (IEA)

response to ionizing radiation (ISO)

Cellular Component

nuclear membrane (ISO)

nucleolus (ISO)

nucleoplasm (ISO)

nucleus (IEA)

Molecular Function

DNA exonuclease activity (ISO)

exonuclease activity (IEA)

nuclease activity (IEA)

nucleic acid binding (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Aen
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	131,722,868 - 131,745,835 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936483	14,601,671 - 14,611,613 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

AEN
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	88,604,683 - 88,632,281 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	88,621,337 - 88,632,281 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	89,164,571 - 89,175,512 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	86,965,593 - 86,976,516 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	15	65,565,411 - 65,576,403 (+)	NCBI		Celera
Cytogenetic Map	15	q26.1	NCBI
HuRef	15	65,276,424 - 65,287,417 (+)	NCBI		HuRef
CHM1_1	15	89,006,164 - 89,017,154 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	15	86,359,390 - 86,386,993 (+)	NCBI		T2T-CHM13v2.0

Aen
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	78,545,675 - 78,560,957 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	78,545,602 - 78,560,957 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	78,895,927 - 78,911,209 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	78,895,854 - 78,911,209 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	86,040,813 - 86,053,719 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	78,769,440 - 78,782,346 (+)	NCBI		MGSCv36	mm8
Celera	7	76,301,311 - 76,311,341 (+)	NCBI		Celera
Cytogenetic Map	7	D2	NCBI
cM Map	7	44.83	NCBI

Aen
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	142,224,499 - 142,233,902 (+)	NCBI		GRCr8
mRatBN7.2	1	132,815,094 - 132,824,522 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	132,815,142 - 132,824,523 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	140,728,011 - 140,737,404 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	147,897,432 - 147,906,825 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	140,815,119 - 140,824,512 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	140,584,328 - 140,593,749 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	140,584,380 - 140,593,745 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	141,559,299 - 141,568,695 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	134,615,998 - 134,625,367 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	134,687,039 - 134,703,710 (+)	NCBI
Celera	1	124,884,104 - 124,893,474 (+)	NCBI		Celera
Cytogenetic Map	1	q31	NCBI

Aen
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955416	16,331,290 - 16,338,078 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955416	16,328,655 - 16,338,069 (-)	NCBI	ChiLan1.0	ChiLan1.0

AEN
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	78,093,519 - 78,177,424 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	81,798,032 - 81,881,972 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	67,237,871 - 67,321,808 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	86,502,347 - 86,529,579 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	86,518,204 - 86,529,579 (+)	Ensembl	panpan1.1		panPan2

AEN
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	51,797,251 - 51,819,385 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	51,809,975 - 51,819,394 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	54,446,831 - 54,455,924 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	3	52,229,881 - 52,238,971 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	3	52,217,677 - 52,239,164 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	3	51,752,639 - 51,761,739 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	3	51,962,832 - 51,971,929 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	3	52,301,829 - 52,310,943 (+)	NCBI		UU_Cfam_GSD_1.0

AEN
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	191,200,632 - 191,219,961 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	191,200,625 - 191,211,884 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	212,633,431 - 212,644,691 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

AEN
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	29	7,160,445 - 7,172,082 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	29	7,165,964 - 7,172,304 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666059	39,676,015 - 39,695,221 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Aen
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624768	15,931,607 - 15,940,690 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005320122	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013356342	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021722888	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040275861	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040275862	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040275863	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040275864	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040275865	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040275866	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040275867	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010003700	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_005320122 ⟹ XP_005320179

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	131,722,868 - 131,732,890 (-)	NCBI
SpeTri2.0	NW_004936483	14,601,671 - 14,611,613 (+)	NCBI

Sequence:

show sequence

GCGGGAGCTGCCAGCTGCCTGGGCGCCACGTGCTCGCCGGAAGAGACGTCCGCGGTTTCAGGCT
GCCACCCGATTGAAAGATTGCTTCCCAGGCTTCCCTTGCCCTGAGCTCAGAGCTGACTGGCATG
GTACCTGAGGAAGCCCCTGAGTCTGCTCAGTGCCCATGCTTGTCCCTTACCAACCCCAGTGCCA
GGGATGTGGTTCGAAGAAGGCACAAGAGGAGGAGCCGACAGCACCAACGCTTCATGGCCCGGAA
GGCCTTGCTACAGGAGCAGGGGCTGCTGACCATGCCACCGGAACAAGGCTCCTCCCTGCTGCCT
GCCCCTTTGGAGGTGCCCTCAGACGCTGAAGCTGCTGGCAGTGGGAGGCAGCATCCCAGGGCTG
AATTTGGCAGTGGTGGCCCATATAGCAAAAGGCTCACCTCCAGGGAAGCTTCAGGGCCCTTGCC
CAGCAAGTGTGTAGCTATTGACTGTGAGATGGTGGGCACAGGACCTCGAGGGCGGGTGAGTGAG
CTTGCCCGCTGCTCTGTGGTGAGTTACCATGGTGATGTCCTCTATGACAAGTACATTCGGCCTG
AGATGCCCATCGTTGACTACCGCACTCGCTGGAGCGGCATCACTCGGCAGCACATGCGCAAGGC
CATCCCCTTCCAGGTGGCCCAAAAAGAGATCCTTAAGCTCCTGAAGGGCAAGGTGGTAGTGGGC
CATGCGCTGCACAATGACTTCCAGGCCCTCAAGTACGTCCACCCTCGGAGCCAGACCCGTGATA
CCACTTATGTCCCAAACCTGCTCAGTCAGCCTGACCTCCACACCCGAGCCAGAGTCTCTCTTAA
GGACCTGGCCCTGCAGTTGCTGCATAAGAAGATCCAGGTGGGCCAGCATGGGCACTCATCCGTG
GAAGATGCCACAACAGCCATGGAGCTGTACCGGCTGGTGGAGGCGCAGTGGGAACAGCAGGCGG
CCAGTAGCTTCTGGGCCCATCCTGAGGACAGAGAGCCTGATAGCAGCACTGACATGGAGCAATA
TATGGAGGACCAATACTGGCCTGATGACCTGGCCCAGGACACCACAGGAGGCACCGGGGGAGTA
CAGGATGGAAGGGAATGAGACAAAGGAGTGTGGTGGGTGGGAAGTAGGGTTCAGGGCAGCACTG
GGCTGTCCATCCTGGGCAGGACTGGCAGGATGCAGCCTACCTGTCCCAAGGTCACAGCAGCTAG
GATCATTGTCCTCTACACCCTCCGCCTACAGAACAGCCCTCTGTCCCTGAGGGCTGTTGTAGTT
CTTTCTCCTGACTCCTGTGATTTTGCTGATGGCACTTTATAGATTCCATGGAAATGGCAGGTGG
ACTGTCACTGGCTTTCTCCATCTCCATGTGTCCTGGACCGTGCTGTGCTAGCTACAGGGATAAC
ATCTCCCTGGGGTGGGGGGATGGGGTTCAGTCCCCGGAGTTCCCTTATGTTAATTTATGTGACA
AAATTTTATTTAGTTTTTGTTGCTGCCTCTTCCTCCATAGTCATGTTCAGATTCAGAATAAATA
TGTTCTGAAGTTAAAAGAATTAAGGCCTCTGAAGGGGACATTTCTTCTCATCTTGAGTTGGAAC
CCTGGTTACAGCCATTGTAAGAAGTTTTATGTCCCATGGTGCCTGTCCCCTGCCTTCTAGGCTG
CAATAGAATAGGAGAGCCCACAGCCTCCCTTGGCCCCTTCACAAGCGTGACATCAGAATCACAG
GTCACAGCTCACAAGGGAGAGCAGAGAAGCTTTGGATAAGAACTGGCATATTTATTTATTATCC
CAAATCAGGAATTCTTTGCCCATCCAGCACTAGGCTCCTTTACACAAAGCCTGAGAAACAGTAT
GGTTTAATTTTGCCCCCCCCCACCCCCTGAGGAGTTGTGTTGCCCTTACATAGAGCAAGTGCCA
GCCTTGGAAACAGTCTACATAGTTGCTGGGGCAGGTATGGCAGCTATAAAGTGTCCCTGTACCT
GGTGCCTTTCAGCTTTATAATTAACAGTTACACTGTGGTTTGGGAGGGGGGTTAATTCCTATAA
AAATGTTTTCTGAGGGGAAATTTTGGGTTACTAGGACAACCAAGGGCTCAGGTGACACAGACCT
CCAAACTCCATCTTTATTGCCACTTACAGTCCCCATCTTTACTGCCACTTAGCTTTGAGACTTC
AGACAAGCCTGTGACTTTACCCTTGAGCCTGTTTCCTCATCTGTAAAATGGGCAGAGTGATAAA
GCCTACGGGTGGTTAGGAGGATTCATTGTTAGGTGCCTTGCACCTGTCCTGAGTGAATGGGCTA
CTTACTGTTCATTCAGGACAATGCCCAGACACTGAATCCTAGATGGAACAGTATTGGCTTAGAG
AGCTGTCTTTGCTTGCCTGTCCCAGCAGGTGGGGCCTGGGCCCATGCAGGCTGGGATGAGGGCA
GGGCATGGAGCTTCAGTGTATCTTGTCTAATGCTATCAATTGCTGGTTTCTTGTCAGCATCCTG
TCACTGTGTGCAGGAAGTGATGACAGAGCAAGGCAACACAGGGTCAGGGAGGGAGGGACACTAC
TGAAACCACACCACCCACTCGTCAGCCGAGGCTCCACTGCACAAACCCAGGTCAGAGACTGCGG
TCACCAGCTCCTCCCTATCAGCAGAGGAGGAAGCTGGCCAGCCACCTCTAGGACTGACATCTGA
AATCTTTGAAAACCTTGCTAAACACAGCTAAGTAGCATTTTAAATTGGTTTGTGGATTGAAGGA
AAATGGAGCTATTATAGTGGGGAAATGTATTGTTGAAAATTGTTTTGTTGTAGAACCATTTGTT
CTAGAATAAAACACAATTGGAAAAGTG

hide sequence

RefSeq Acc Id:

XM_013356342 ⟹ XP_013211796

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	131,722,868 - 131,732,634 (-)	NCBI
SpeTri2.0	NW_004936483	14,601,754 - 14,611,613 (+)	NCBI

Sequence:

show sequence

GCGTTGCCGGTTCGGGCGGGCTGTCGCGGCGTGTCCAGGGCCGCTGGCGGTCGCGGTGGGGTAG
GGGCGCCTAGCCTCCGCCGACCACACGCTTCGGCCGGGCCTGGGTACCGCCTCCCTCATCCCGG
CTCGGCCTGGACGCCGCGGCCAGCTGCCACCCGATTGAAAGATTGCTTCCCAGGCTTCCCTTGC
CCTGAGCTCAGAGCTGACTGGCATGGTACCTGAGGAAGCCCCTGAGTCTGCTCAGTGCCCATGC
TTGTCCCTTACCAACCCCAGTGCCAGGGATGTGGTTCGAAGAAGGCACAAGAGGAGGAGCCGAC
AGCACCAACGCTTCATGGCCCGGAAGGCCTTGCTACAGGAGCAGGGGCTGCTGACCATGCCACC
GGAACAAGGCTCCTCCCTGCTGCCTGCCCCTTTGGAGGTGCCCTCAGACGCTGAAGCTGCTGGC
AGTGGGAGGCAGCATCCCAGGGCTGAATTTGGCAGTGGTGGCCCATATAGCAAAAGGCTCACCT
CCAGGGAAGCTTCAGGGCCCTTGCCCAGCAAGTGTGTAGCTATTGACTGTGAGATGGTGGGCAC
AGGACCTCGAGGGCGGGTGAGTGAGCTTGCCCGCTGCTCTGTGGTGAGTTACCATGGTGATGTC
CTCTATGACAAGTACATTCGGCCTGAGATGCCCATCGTTGACTACCGCACTCGCTGGAGCGGCA
TCACTCGGCAGCACATGCGCAAGGCCATCCCCTTCCAGGTGGCCCAAAAAGAGATCCTTAAGCT
CCTGAAGGGCAAGGTGGTAGTGGGCCATGCGCTGCACAATGACTTCCAGGCCCTCAAGTACGTC
CACCCTCGGAGCCAGACCCGTGATACCACTTATGTCCCAAACCTGCTCAGTCAGCCTGACCTCC
ACACCCGAGCCAGAGTCTCTCTTAAGGACCTGGCCCTGCAGTTGCTGCATAAGAAGATCCAGGT
GGGCCAGCATGGGCACTCATCCGTGGAAGATGCCACAACAGCCATGGAGCTGTACCGGCTGGTG
GAGGCGCAGTGGGAACAGCAGGCGGCCAGTAGCTTCTGGGCCCATCCTGAGGACAGAGAGCCTG
ATAGCAGCACTGACATGGAGCAATATATGGAGGACCAATACTGGCCTGATGACCTGGCCCAGGA
CACCACAGGAGGCACCGGGGGAGTACAGGATGGAAGGGAATGAGACAAAGGAGTGTGGTGGGTG
GGAAGTAGGGTTCAGGGCAGCACTGGGCTGTCCATCCTGGGCAGGACTGGCAGGATGCAGCCTA
CCTGTCCCAAGGTCACAGCAGCTAGGATCATTGTCCTCTACACCCTCCGCCTACAGAACAGCCC
TCTGTCCCTGAGGGCTGTTGTAGTTCTTTCTCCTGACTCCTGTGATTTTGCTGATGGCACTTTA
TAGATTCCATGGAAATGGCAGGTGGACTGTCACTGGCTTTCTCCATCTCCATGTGTCCTGGACC
GTGCTGTGCTAGCTACAGGGATAACATCTCCCTGGGGTGGGGGGATGGGGTTCAGTCCCCGGAG
TTCCCTTATGTTAATTTATGTGACAAAATTTTATTTAGTTTTTGTTGCTGCCTCTTCCTCCATA
GTCATGTTCAGATTCAGAATAAATATGTTCTGAAGTTAAAAGAATTAAGGCCTCTGAAGGGGAC
ATTTCTTCTCATCTTGAGTTGGAACCCTGGTTACAGCCATTGTAAGAAGTTTTATGTCCCATGG
TGCCTGTCCCCTGCCTTCTAGGCTGCAATAGAATAGGAGAGCCCACAGCCTCCCTTGGCCCCTT
CACAAGCGTGACATCAGAATCACAGGTCACAGCTCACAAGGGAGAGCAGAGAAGCTTTGGATAA
GAACTGGCATATTTATTTATTATCCCAAATCAGGAATTCTTTGCCCATCCAGCACTAGGCTCCT
TTACACAAAGCCTGAGAAACAGTATGGTTTAATTTTGCCCCCCCCCACCCCCTGAGGAGTTGTG
TTGCCCTTACATAGAGCAAGTGCCAGCCTTGGAAACAGTCTACATAGTTGCTGGGGCAGGTATG
GCAGCTATAAAGTGTCCCTGTACCTGGTGCCTTTCAGCTTTATAATTAACAGTTACACTGTGGT
TTGGGAGGGGGGTTAATTCCTATAAAAATGTTTTCTGAGGGGAAATTTTGGGTTACTAGGACAA
CCAAGGGCTCAGGTGACACAGACCTCCAAACTCCATCTTTATTGCCACTTACAGTCCCCATCTT
TACTGCCACTTAGCTTTGAGACTTCAGACAAGCCTGTGACTTTACCCTTGAGCCTGTTTCCTCA
TCTGTAAAATGGGCAGAGTGATAAAGCCTACGGGTGGTTAGGAGGATTCATTGTTAGGTGCCTT
GCACCTGTCCTGAGTGAATGGGCTACTTACTGTTCATTCAGGACAATGCCCAGACACTGAATCC
TAGATGGAACAGTATTGGCTTAGAGAGCTGTCTTTGCTTGCCTGTCCCAGCAGGTGGGGCCTGG
GCCCATGCAGGCTGGGATGAGGGCAGGGCATGGAGCTTCAGTGTATCTTGTCTAATGCTATCAA
TTGCTGGTTTCTTGTCAGCATCCTGTCACTGTGTGCAGGAAGTGATGACAGAGCAAGGCAACAC
AGGGTCAGGGAGGGAGGGACACTACTGAAACCACACCACCCACTCGTCAGCCGAGGCTCCACTG
CACAAACCCAGGTCAGAGACTGCGGTCACCAGCTCCTCCCTATCAGCAGAGGAGGAAGCTGGCC
AGCCACCTCTAGGACTGACATCTGAAATCTTTGAAAACCTTGCTAAACACAGCTAAGTAGCATT
TTAAATTGGTTTGTGGATTGAAGGAAAATGGAGCTATTATAGTGGGGAAATGTATTGTTGAAAA
TTGTTTTGTTGTAGAACCATTTGTTCTAGAATAAAACACAATTGGAAAAGTG

hide sequence

RefSeq Acc Id:

XM_021722888 ⟹ XP_021578563

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	131,722,868 - 131,732,634 (-)	NCBI
SpeTri2.0	NW_004936483	14,601,914 - 14,611,613 (+)	NCBI

Sequence:

show sequence

AACGCCCGAGCCCTTCCCGGTATAGCCGGGCCTCCCTCGCGTCTTGCCGCGGAGAACGCCCAGC
GGGCGGCGAGGCTGCCACCCGATTGAAAGATTGCTTCCCAGGCTTCCCTTGCCCTGAGCTCAGA
GCTGACTGGCATGGTACCTGAGGAAGCCCCTGAGTCTGCTCAGTGCCCATGCTTGTCCCTTACC
AACCCCAGTGCCAGGGATGTGGTTCGAAGAAGGCACAAGAGGAGGAGCCGACAGCACCAACGCT
TCATGGCCCGGAAGGCCTTGCTACAGGAGCAGGGGCTGCTGACCATGCCACCGGAACAAGGCTC
CTCCCTGCTGCCTGCCCCTTTGGAGGTGCCCTCAGACGCTGAAGCTGCTGGCAGTGGGAGGCAG
CATCCCAGGGCTGAATTTGGCAGTGGTGGCCCATATAGCAAAAGGCTCACCTCCAGGGAAGCTT
CAGGGCCCTTGCCCAGCAAGTGTGTAGCTATTGACTGTGAGATGGTGGGCACAGGACCTCGAGG
GCGGGTGAGTGAGCTTGCCCGCTGCTCTGTGGTGAGTTACCATGGTGATGTCCTCTATGACAAG
TACATTCGGCCTGAGATGCCCATCGTTGACTACCGCACTCGCTGGAGCGGCATCACTCGGCAGC
ACATGCGCAAGGCCATCCCCTTCCAGGTGGCCCAAAAAGAGATCCTTAAGCTCCTGAAGGGCAA
GGTGGTAGTGGGCCATGCGCTGCACAATGACTTCCAGGCCCTCAAGTACGTCCACCCTCGGAGC
CAGACCCGTGATACCACTTATGTCCCAAACCTGCTCAGTCAGCCTGACCTCCACACCCGAGCCA
GAGTCTCTCTTAAGGACCTGGCCCTGCAGTTGCTGCATAAGAAGATCCAGGTGGGCCAGCATGG
GCACTCATCCGTGGAAGATGCCACAACAGCCATGGAGCTGTACCGGCTGGTGGAGGCGCAGTGG
GAACAGCAGGCGGCCAGTAGCTTCTGGGCCCATCCTGAGGACAGAGAGCCTGATAGCAGCACTG
ACATGGAGCAATATATGGAGGACCAATACTGGCCTGATGACCTGGCCCAGGACACCACAGGAGG
CACCGGGGGAGTACAGGATGGAAGGGAATGAGACAAAGGAGTGTGGTGGGTGGGAAGTAGGGTT
CAGGGCAGCACTGGGCTGTCCATCCTGGGCAGGACTGGCAGGATGCAGCCTACCTGTCCCAAGG
TCACAGCAGCTAGGATCATTGTCCTCTACACCCTCCGCCTACAGAACAGCCCTCTGTCCCTGAG
GGCTGTTGTAGTTCTTTCTCCTGACTCCTGTGATTTTGCTGATGGCACTTTATAGATTCCATGG
AAATGGCAGGTGGACTGTCACTGGCTTTCTCCATCTCCATGTGTCCTGGACCGTGCTGTGCTAG
CTACAGGGATAACATCTCCCTGGGGTGGGGGGATGGGGTTCAGTCCCCGGAGTTCCCTTATGTT
AATTTATGTGACAAAATTTTATTTAGTTTTTGTTGCTGCCTCTTCCTCCATAGTCATGTTCAGA
TTCAGAATAAATATGTTCTGAAGTTAAAAGAATTAAGGCCTCTGAAGGGGACATTTCTTCTCAT
CTTGAGTTGGAACCCTGGTTACAGCCATTGTAAGAAGTTTTATGTCCCATGGTGCCTGTCCCCT
GCCTTCTAGGCTGCAATAGAATAGGAGAGCCCACAGCCTCCCTTGGCCCCTTCACAAGCGTGAC
ATCAGAATCACAGGTCACAGCTCACAAGGGAGAGCAGAGAAGCTTTGGATAAGAACTGGCATAT
TTATTTATTATCCCAAATCAGGAATTCTTTGCCCATCCAGCACTAGGCTCCTTTACACAAAGCC
TGAGAAACAGTATGGTTTAATTTTGCCCCCCCCCACCCCCTGAGGAGTTGTGTTGCCCTTACAT
AGAGCAAGTGCCAGCCTTGGAAACAGTCTACATAGTTGCTGGGGCAGGTATGGCAGCTATAAAG
TGTCCCTGTACCTGGTGCCTTTCAGCTTTATAATTAACAGTTACACTGTGGTTTGGGAGGGGGG
TTAATTCCTATAAAAATGTTTTCTGAGGGGAAATTTTGGGTTACTAGGACAACCAAGGGCTCAG
GTGACACAGACCTCCAAACTCCATCTTTATTGCCACTTACAGTCCCCATCTTTACTGCCACTTA
GCTTTGAGACTTCAGACAAGCCTGTGACTTTACCCTTGAGCCTGTTTCCTCATCTGTAAAATGG
GCAGAGTGATAAAGCCTACGGGTGGTTAGGAGGATTCATTGTTAGGTGCCTTGCACCTGTCCTG
AGTGAATGGGCTACTTACTGTTCATTCAGGACAATGCCCAGACACTGAATCCTAGATGGAACAG
TATTGGCTTAGAGAGCTGTCTTTGCTTGCCTGTCCCAGCAGGTGGGGCCTGGGCCCATGCAGGC
TGGGATGAGGGCAGGGCATGGAGCTTCAGTGTATCTTGTCTAATGCTATCAATTGCTGGTTTCT
TGTCAGCATCCTGTCACTGTGTGCAGGAAGTGATGACAGAGCAAGGCAACACAGGGTCAGGGAG
GGAGGGACACTACTGAAACCACACCACCCACTCGTCAGCCGAGGCTCCACTGCACAAACCCAGG
TCAGAGACTGCGGTCACCAGCTCCTCCCTATCAGCAGAGGAGGAAGCTGGCCAGCCACCTCTAG
GACTGACATCTGAAATCTTTGAAAACCTTGCTAAACACAGCTAAGTAGCATTTTAAATTGGTTT
GTGGATTGAAGGAAAATGGAGCTATTATAGTGGGGAAATGTATTGTTGAAAATTGTTTTGTTGT
AGAACCATTTGTTCTAGAATAAAACACAATTGGAAAAGTG

hide sequence

RefSeq Acc Id:

XM_040275861 ⟹ XP_040131795

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	131,722,868 - 131,745,835 (-)	NCBI

RefSeq Acc Id:

XM_040275862 ⟹ XP_040131796

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	131,722,868 - 131,745,835 (-)	NCBI

RefSeq Acc Id:

XM_040275863 ⟹ XP_040131797

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	131,722,868 - 131,745,835 (-)	NCBI

RefSeq Acc Id:

XM_040275864 ⟹ XP_040131798

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	131,722,868 - 131,745,835 (-)	NCBI

RefSeq Acc Id:

XM_040275865 ⟹ XP_040131799

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	131,722,868 - 131,745,835 (-)	NCBI

RefSeq Acc Id:

XM_040275866 ⟹ XP_040131800

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	131,722,868 - 131,732,741 (-)	NCBI

RefSeq Acc Id:

XM_040275867 ⟹ XP_040131801

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	131,722,868 - 131,741,887 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005320179	(Get FASTA)	NCBI Sequence Viewer
	XP_013211796	(Get FASTA)	NCBI Sequence Viewer
	XP_021578563	(Get FASTA)	NCBI Sequence Viewer
	XP_040131795	(Get FASTA)	NCBI Sequence Viewer
	XP_040131796	(Get FASTA)	NCBI Sequence Viewer
	XP_040131797	(Get FASTA)	NCBI Sequence Viewer
	XP_040131798	(Get FASTA)	NCBI Sequence Viewer
	XP_040131799	(Get FASTA)	NCBI Sequence Viewer
	XP_040131800	(Get FASTA)	NCBI Sequence Viewer
	XP_040131801	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000010373.3
GenBank Protein	KAG3262606	(Get FASTA)	NCBI Sequence Viewer
	KAG3262607	(Get FASTA)	NCBI Sequence Viewer
	KAG3262608	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005320179 ⟸ XM_005320122

- Sequence:

show sequence

MVPEEAPESAQCPCLSLTNPSARDVVRRRHKRRSRQHQRFMARKALLQEQGLLTMPPEQGSSLL
PAPLEVPSDAEAAGSGRQHPRAEFGSGGPYSKRLTSREASGPLPSKCVAIDCEMVGTGPRGRVS
ELARCSVVSYHGDVLYDKYIRPEMPIVDYRTRWSGITRQHMRKAIPFQVAQKEILKLLKGKVVV
GHALHNDFQALKYVHPRSQTRDTTYVPNLLSQPDLHTRARVSLKDLALQLLHKKIQVGQHGHSS
VEDATTAMELYRLVEAQWEQQAASSFWAHPEDREPDSSTDMEQYMEDQYWPDDLAQDTTGGTGG
VQDGRE

hide sequence

RefSeq Acc Id:

XP_013211796 ⟸ XM_013356342

- Sequence:

show sequence

MVPEEAPESAQCPCLSLTNPSARDVVRRRHKRRSRQHQRFMARKALLQEQGLLTMPPEQGSSLL
PAPLEVPSDAEAAGSGRQHPRAEFGSGGPYSKRLTSREASGPLPSKCVAIDCEMVGTGPRGRVS
ELARCSVVSYHGDVLYDKYIRPEMPIVDYRTRWSGITRQHMRKAIPFQVAQKEILKLLKGKVVV
GHALHNDFQALKYVHPRSQTRDTTYVPNLLSQPDLHTRARVSLKDLALQLLHKKIQVGQHGHSS
VEDATTAMELYRLVEAQWEQQAASSFWAHPEDREPDSSTDMEQYMEDQYWPDDLAQDTTGGTGG
VQDGRE

hide sequence

RefSeq Acc Id:

XP_021578563 ⟸ XM_021722888

- Sequence:

show sequence

MVPEEAPESAQCPCLSLTNPSARDVVRRRHKRRSRQHQRFMARKALLQEQGLLTMPPEQGSSLL
PAPLEVPSDAEAAGSGRQHPRAEFGSGGPYSKRLTSREASGPLPSKCVAIDCEMVGTGPRGRVS
ELARCSVVSYHGDVLYDKYIRPEMPIVDYRTRWSGITRQHMRKAIPFQVAQKEILKLLKGKVVV
GHALHNDFQALKYVHPRSQTRDTTYVPNLLSQPDLHTRARVSLKDLALQLLHKKIQVGQHGHSS
VEDATTAMELYRLVEAQWEQQAASSFWAHPEDREPDSSTDMEQYMEDQYWPDDLAQDTTGGTGG
VQDGRE

hide sequence

RefSeq Acc Id:

XP_040131796 ⟸ XM_040275862

RefSeq Acc Id:

XP_040131799 ⟸ XM_040275865

RefSeq Acc Id:

XP_040131798 ⟸ XM_040275864

RefSeq Acc Id:

XP_040131795 ⟸ XM_040275861

RefSeq Acc Id:

XP_040131797 ⟸ XM_040275863

RefSeq Acc Id:

XP_040131801 ⟸ XM_040275867

RefSeq Acc Id:

XP_040131800 ⟸ XM_040275866

Protein Domains

Exonuclease

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000011560	UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000011558.3	UniProtKB/TrEMBL
Gene3D-CATH	3.30.420.10	UniProtKB/TrEMBL
InterPro	Exonuclease_RNaseT/DNA_pol3	UniProtKB/TrEMBL
	REXO1/3/4-like	UniProtKB/TrEMBL
	RNaseH-like_sf	UniProtKB/TrEMBL
	RNaseH_sf	UniProtKB/TrEMBL
NCBI Gene	Aen	ENTREZGENE
PANTHER	APOPTOSIS-ENHANCING NUCLEASE	UniProtKB/TrEMBL
	RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED	UniProtKB/TrEMBL
Pfam	RNase_T	UniProtKB/TrEMBL
SMART	EXOIII	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53098	UniProtKB/TrEMBL
UniProt	I3MHK0_ICTTR	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD