Gip (gastric inhibitory polypeptide)

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Gene: Gip (gastric inhibitory polypeptide) Ictidomys tridecemlineatus

Analyze

Symbol:

Gip

Name:

gastric inhibitory polypeptide

RGD ID:

12633016

Description:

ENCODES a protein that exhibits signaling receptor binding (ortholog); INVOLVED IN adult locomotory behavior (ortholog); digestive system development (ortholog); endocrine pancreas development (ortholog); ASSOCIATED WITH Anorexia (ortholog); autonomic nervous system disease (ortholog); Experimental Diabetes Mellitus (ortholog); FOUND IN cytoplasm (ortholog); extracellular space (ortholog); neuronal cell body (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

RGD Orthologs

Human

Mouse

Rat

Chinchilla

Bonobo

Dog

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936490	12,487,025 - 12,492,214 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Anorexia (ISO)

autonomic nervous system disease (ISO)

Experimental Diabetes Mellitus (ISO)

hyperglycemia (ISO)

hyperinsulinism (ISO)

hypothyroidism (ISO)

obesity (ISO)

pancreas disease (ISO)

polycystic ovary syndrome (ISO)

Starvation (ISO)

type 2 diabetes mellitus (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adult locomotory behavior (ISO)

digestive system development (ISO)

endocrine pancreas development (ISO)

exploration behavior (ISO)

female pregnancy (ISO)

long-term synaptic potentiation (ISO)

memory (ISO)

positive regulation of cAMP-mediated signaling (ISO)

positive regulation of glucagon secretion (ISO)

positive regulation of glucose transmembrane transport (ISO)

positive regulation of insulin secretion (ISO)

positive regulation of synaptic transmission (ISO)

response to acidic pH (ISO)

response to amino acid (ISO)

response to axon injury (ISO)

response to carbohydrate (ISO)

response to drug (ISO)

response to glucose (ISO)

response to lipid (ISO)

response to nutrient levels (ISO)

response to organic cyclic compound (ISO)

response to peptide hormone (ISO)

response to selenium ion (ISO)

response to starvation (ISO)

sensory perception of pain (ISO)

triglyceride homeostasis (ISO)

Cellular Component

cytoplasm (ISO)

extracellular space (ISO)

neuronal cell body (ISO)

Molecular Function

protein binding (ISO)

signaling receptor binding (ISO)

References

Genomics

Comparative Map Data

Gip
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936490	12,487,025 - 12,492,214 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GIP
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	17	48,958,554 - 48,968,596 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	17	48,958,554 - 48,968,596 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	17	47,035,918 - 47,045,955 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	44,390,917 - 44,400,954 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	17	44,390,916 - 44,400,954	NCBI
Celera	17	43,490,595 - 43,500,198 (-)	NCBI
Cytogenetic Map	17	q21.32	NCBI
HuRef	17	42,403,606 - 42,413,192 (-)	NCBI		HuRef
CHM1_1	17	47,101,692 - 47,111,260 (-)	NCBI		CHM1_1

Gip
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	95,915,358 - 95,921,657 (+)	NCBI	GRCm39		mm39
GRCm38	11	96,024,532 - 96,030,831 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	96,024,545 - 96,030,831 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	95,885,859 - 95,892,142 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	11	95,840,635 - 95,846,918 (+)	NCBI			mm8
Celera	11	105,675,017 - 105,681,265 (+)	NCBI		Celera
Cytogenetic Map	11	D	NCBI

Gip
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	10	83,835,080 - 83,848,399 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	83,840,303 - 83,848,396 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	83,645,328 - 83,653,501 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	84,732,705 - 84,740,801 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	10	84,747,074 - 84,755,168 (+)	NCBI
Celera	10	79,736,495 - 79,744,591 (+)	NCBI		Celera
Cytogenetic Map	10	q26	NCBI

Gip
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955451	12,390,938 - 12,396,599 (+)	NCBI	ChiLan1.0	ChiLan1.0

GIP
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	17	8,554,736 - 8,561,849 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
Mhudiblu_PPA_v0	17	8,573,104 - 8,580,424 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

GIP
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	9	25,167,926 - 25,174,575 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	9	25,167,938 - 25,174,402 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

GIP
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	25,160,789 - 25,167,940 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	25,160,783 - 25,167,952 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	25,126,659 - 25,133,815 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LOC103243632
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	69,367,030 - 69,377,563 (-)	NCBI
ChlSab1.1 Ensembl	16	69,367,207 - 69,377,155 (-)	Ensembl

Gip
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624795	5,331,214 - 5,333,425 (-)	NCBI

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005321706	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGTP01023177	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

XM_005321706 ⟹ XP_005321763

RefSeq Status:

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0	NW_004936490	12,487,025 - 12,492,214 (+)	NCBI

Sequence:

show sequence

ATGATGGCCATGAAGACCTGTTCTCTGCTCTTGGTGCTCTTGTTCCTGGCAGTGGGGCTGGGAG
AAAAGGAAGAGGCTTTCTCCAGATCCCATGCGAAGGTTCCTGGCTCCCGACCTCTAGGACCAAG
GTATGCAGAGGGAACTTTCATCAGTGACTACAGCATTGCCATGGACAAGATCCACCAGCAAGAC
TTTGTGAACTGGCTGCTGGCCCAGAAGGGGAAGAAGAACAACTGGAAACACAACATCACCCAGA
GGGAGGCCCAGGCCCTGGAACTGGCTGGGCAATCTCAAGGGAATAAGGAGGCACCAGAGCAGCA
GAGCTCCCTACCCAAGAACCCTGGTGATGAAGATCTACTAAAGGAGTTGTTGATTCAAAAGCTG
CTGGCCTGGATGGTGGACCAGACAGAGCTCTGCACACTCAGGTGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005321763	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	XP_005321763 ⟸ XM_005321706
- Sequence:	show sequence MMAMKTCSLLLVLLFLAVGLGEKEEAFSRSHAKVPGSRPLGPRYAEGTFISDYSIAMDKIHQQD FVNWLLAQKGKKNNWKHNITQREAQALELAGQSQGNKEAPEQQSSLPKNPGDEDLLKELLIQKL LAWMVDQTELCTLR hide sequence

Protein Domains

GLUCAGON

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000004043	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSSTOP00000003611	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000004027	ENTREZGENE, UniProtKB/TrEMBL
InterPro	GIP	UniProtKB/TrEMBL
	Glucagon_GIP_secretin_VIP	UniProtKB/TrEMBL
NCBI Gene	Gip	ENTREZGENE
PANTHER	PTHR15211	UniProtKB/TrEMBL
Pfam	Hormone_2	UniProtKB/TrEMBL
PROSITE	GLUCAGON	UniProtKB/TrEMBL
SMART	GLUCA	UniProtKB/TrEMBL
UniProt	I3M3G3_ICTTR	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD