Wrnip1 (WRN helicase interacting protein 1) - Rat Genome Database

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Gene: Wrnip1 (WRN helicase interacting protein 1) Ictidomys tridecemlineatus
Analyze
Symbol: Wrnip1
Name: WRN helicase interacting protein 1
RGD ID: 12629321
Description: ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); DNA binding (inferred); INVOLVED IN DNA duplex unwinding (inferred); DNA repair (inferred); DNA replication (inferred); FOUND IN chromosome, telomeric region (inferred); nucleus (inferred); perinuclear region of cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATPase WRNIP1; Werner helicase interacting protein 1; Werner helicase interacting protein 1, transcript variant X1; Werner helicase interacting protein 1, transcript variant X2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494622,746,687 - 22,767,469 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366333,853,058 - 3,874,121 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366333,853,201 - 3,873,983 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Wrnip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494622,746,687 - 22,767,469 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366333,853,058 - 3,874,121 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366333,853,201 - 3,873,983 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WRNIP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3862,765,393 - 2,786,952 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl62,765,393 - 2,786,952 (+)EnsemblGRCh38hg38GRCh38
GRCh3762,765,627 - 2,787,186 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3662,710,665 - 2,730,978 (+)NCBINCBI36Build 36hg18NCBI36
Build 3462,710,664 - 2,730,977NCBI
Celera63,994,624 - 4,014,940 (+)NCBICelera
Cytogenetic Map6p25.2NCBI
HuRef62,638,804 - 2,659,415 (+)NCBIHuRef
CHM1_162,768,240 - 2,788,553 (+)NCBICHM1_1
T2T-CHM13v2.062,631,255 - 2,653,114 (+)NCBIT2T-CHM13v2.0
Wrnip1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391332,986,013 - 33,006,593 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1332,986,021 - 33,006,592 (+)EnsemblGRCm39 Ensembl
GRCm381332,802,030 - 32,822,610 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1332,802,038 - 32,822,609 (+)EnsemblGRCm38mm10GRCm38
MGSCv371332,893,899 - 32,914,479 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361332,809,503 - 32,830,074 (+)NCBIMGSCv36mm8
Celera1333,010,944 - 33,032,851 (+)NCBICelera
Cytogenetic Map13A3.2NCBI
cM Map1313.74NCBI
Wrnip1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81731,830,159 - 31,850,408 (-)NCBIGRCr8
mRatBN7.21731,621,410 - 31,641,659 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1731,621,411 - 31,641,659 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1731,456,553 - 31,476,744 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01733,060,327 - 33,080,518 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01731,452,320 - 31,472,509 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01732,933,395 - 32,953,641 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1732,933,396 - 32,953,641 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01734,825,601 - 34,845,847 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41737,982,094 - 38,002,342 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11737,984,934 - 38,005,183 (-)NCBI
Celera1731,183,744 - 31,203,992 (-)NCBICelera
Cytogenetic Map17p12NCBI
Wrnip1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546510,574,551 - 10,593,780 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546510,574,601 - 10,594,570 (-)NCBIChiLan1.0ChiLan1.0
WRNIP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2517,391,235 - 17,412,245 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1613,383,335 - 13,403,453 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v062,587,170 - 2,608,179 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.162,688,066 - 2,711,062 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl62,691,235 - 2,711,062 (+)Ensemblpanpan1.1panPan2
WRNIP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1353,103,507 - 3,127,657 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl353,103,418 - 3,127,504 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha353,110,859 - 3,135,627 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0353,158,467 - 3,183,106 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl353,158,020 - 3,183,103 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1353,034,380 - 3,058,999 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0353,056,962 - 3,081,532 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0354,389,321 - 4,413,936 (+)NCBIUU_Cfam_GSD_1.0
WRNIP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl71,656,984 - 1,667,879 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.171,656,952 - 1,667,885 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.271,752,826 - 1,766,919 (+)NCBISscrofa10.2Sscrofa10.2susScr3
WRNIP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11769,366,565 - 69,386,950 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1769,366,389 - 69,386,932 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660442,711,607 - 2,732,063 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wrnip1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475622,034,137 - 22,054,253 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475622,034,252 - 22,054,236 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000026623   ⟹   ENSSTOP00000015001
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366333,853,058 - 3,874,121 (+)Ensembl
RefSeq Acc Id: XM_005335162   ⟹   XP_005335219
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494622,746,687 - 22,767,469 (-)NCBI
SpeTri2.0NW_0049366333,853,201 - 3,873,983 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013362803   ⟹   XP_013218257
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494622,747,435 - 22,767,342 (-)NCBI
SpeTri2.0NW_0049366333,853,254 - 3,872,499 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040282193   ⟹   XP_040138127
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494622,747,383 - 22,767,342 (-)NCBI
Protein Sequences
Protein RefSeqs XP_005335219 (Get FASTA)   NCBI Sequence Viewer  
  XP_013218257 (Get FASTA)   NCBI Sequence Viewer  
  XP_040138127 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000015001.1
GenBank Protein KAG3288794 (Get FASTA)   NCBI Sequence Viewer  
  KAG3288795 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005335219   ⟸   XM_005335162
- Peptide Label: isoform X1
- UniProtKB: I3MSA6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013218257   ⟸   XM_013362803
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_040138127   ⟸   XM_040282193
- Peptide Label: isoform X2
Ensembl Acc Id: ENSSTOP00000015001   ⟸   ENSSTOT00000026623
Protein Domains
UBZ4-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000026347 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000026623.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.8.60 UniProtKB/TrEMBL
  1.20.272.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
  DNA polymerase III clamp loader subunits, C-terminal domain UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  AAA_assoc_2 UniProtKB/TrEMBL
  AAA_ATPase_RarA/MGS1/WRNIP1 UniProtKB/TrEMBL
  ATPase_AAA_core UniProtKB/TrEMBL
  DNA_pol3_clamp-load_cplx_C UniProtKB/TrEMBL
  MgsA_C UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Rad18_UBZ4 UniProtKB/TrEMBL
  Znf-WRNIP1_ubi UniProtKB/TrEMBL
NCBI Gene Wrnip1 ENTREZGENE
PANTHER ATPASE WRNIP1 UniProtKB/TrEMBL
  WERNER HELICASE-INTERACTING PROTEIN 1 FAMILY MEMBER UniProtKB/TrEMBL
Pfam AAA UniProtKB/TrEMBL
  AAA_assoc_2 UniProtKB/TrEMBL
  MgsA_C UniProtKB/TrEMBL
  zf-WRNIP1_ubi UniProtKB/TrEMBL
PROSITE ZF_UBZ4 UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
  ZnF_Rad18 UniProtKB/TrEMBL
Superfamily-SCOP SSF48019 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt I3MSA6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-16 Wrnip1  WRN helicase interacting protein 1    Werner helicase interacting protein 1  Symbol and/or name change 5135510 APPROVED