G6pd (glucose-6-phosphate dehydrogenase) - Rat Genome Database

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Gene: G6pd (glucose-6-phosphate dehydrogenase) Ictidomys tridecemlineatus
Analyze
Symbol: G6pd
Name: glucose-6-phosphate dehydrogenase
RGD ID: 12621823
Description: ENCODES a protein that exhibits carbohydrate binding (ortholog); glucose binding (ortholog); glucose-6-phosphate dehydrogenase activity (ortholog); INVOLVED IN angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure (ortholog); angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure (ortholog); cellular response to oxidative stress (ortholog); PARTICIPATES IN pentose phosphate pathway; pentose phosphate pathway - oxidative phase; ribose 5-phosphate isomerase deficiency pathway; ASSOCIATED WITH acute kidney failure (ortholog); adrenoleukodystrophy (ortholog); ALAD-Deficiency Porphyria (ortholog); FOUND IN centriolar satellite (ortholog); cytoplasm (ortholog); cytoplasmic side of plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: glucose-6-phosphate 1-dehydrogenase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X119,532,130 - 119,548,019 (-)NCBI
SpeTri2.0NW_0049368091,269,900 - 1,285,853 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute kidney failure  (ISO)
adrenoleukodystrophy  (ISO)
ALAD-Deficiency Porphyria  (ISO)
anemia  (ISO)
Angioedema Induced by ACE Inhibitors  (ISO)
autistic disorder  (ISO)
Bloch-Sulzberger syndrome  (ISO)
Brain Injuries  (ISO)
cataract  (ISO)
cerebrovascular disease  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
cholestasis  (ISO)
chronic granulomatous disease  (ISO)
congenital hemolytic anemia  (ISO)
congenital hypothyroidism  (ISO)
congenital nonspherocytic hemolytic anemia  (ISO)
contact dermatitis  (ISO)
diabetes mellitus  (ISO)
Diabetic Nephropathies  (ISO)
Ectodermal Dysplasia and Immunodeficiency 1  (ISO)
Experimental Diabetes Mellitus  (ISO)
favism  (ISO)
Fever  (ISO)
genetic disease  (ISO)
glucosephosphate dehydrogenase deficiency  (ISO)
Hemolysis  (ISO)
hemolytic anemia  (ISO)
hepatic encephalopathy  (ISO)
hepatocellular carcinoma  (ISO)
Hypercholesterolemia  (ISO)
hyperhomocysteinemia  (ISO)
Hypertriglyceridemia  (ISO)
hypomelanosis of Ito  (ISO)
immunodeficiency 33  (ISO)
Insulin Resistance  (ISO)
kidney disease  (ISO)
Liver Injury  (ISO)
malaria  (ISO)
Metabolic Syndrome  (ISO)
Multi-Infarct Dementia  (ISO)
myocardial infarction  (ISO)
Neonatal Hyperbilirubinemia  (ISO)
neonatal jaundice  (ISO)
non-alcoholic fatty liver disease  (ISO)
obesity  (ISO)
osteoporosis  (ISO)
phagocyte bactericidal dysfunction  (ISO)
phenylketonuria  (ISO)
Plasmodium falciparum malaria  (ISO)
Pulmonary Hypertension, Hypoxia-Induced  (ISO)
renovascular hypertension  (ISO)
Reperfusion Injury  (ISO)
severe congenital encephalopathy due to MECP2 mutation  (ISO)
Testicular Injury  (ISO)
transient cerebral ischemia  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
X-linked parkinsonism-spasticity syndrome  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
G6pd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X119,532,130 - 119,548,019 (-)NCBI
SpeTri2.0NW_0049368091,269,900 - 1,285,853 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
G6PD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX154,531,391 - 154,547,572 (-)EnsemblGRCh38hg38GRCh38
GRCh38X154,531,390 - 154,547,569 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X153,759,605 - 153,775,784 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X153,412,800 - 153,428,981 (-)NCBINCBI36hg18NCBI36
Build 34X153,323,309 - 153,339,173NCBI
CeleraX153,920,654 - 153,936,836 (-)NCBI
Cytogenetic MapXq28NCBI
HuRefX142,336,102 - 142,352,295 (-)NCBIHuRef
CHM1_1X153,671,374 - 153,687,570 (-)NCBICHM1_1
G6pdx
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X73,453,089 - 73,472,486 (-)NCBIGRCm39mm39
GRCm39 EnsemblX73,453,089 - 73,472,800 (-)Ensembl
GRCm38X74,409,483 - 74,428,880 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX74,409,483 - 74,429,194 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X71,654,825 - 71,674,500 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X70,662,206 - 70,681,881 (-)NCBImm8
CeleraX65,663,679 - 65,683,364 (-)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX38.0NCBI
G6pd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X152,201,081 - 152,220,863 (-)NCBI
Rnor_6.0 EnsemblX156,274,800 - 156,293,926 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X156,274,800 - 156,293,935 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01152,015,532 - 152,034,676 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X160,186,450 - 160,192,316 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1135,676,941 - 135,696,556 (+)NCBICelera
Cytogenetic MapXq37NCBI
G6pd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555801,045,294 - 1,057,083 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555801,045,294 - 1,058,129 (-)NCBIChiLan1.0ChiLan1.0
G6PD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X153,843,092 - 153,860,675 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX153,843,092 - 153,860,674 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X143,972,798 - 143,988,960 (-)NCBIMhudiblu_PPA_v0panPan3
G6PD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X122,217,317 - 122,231,862 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX122,205,683 - 122,231,678 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0X125,358,989 - 125,373,645 (-)NCBI
UMICH_Zoey_3.1X121,127,964 - 121,142,608 (-)NCBI
UNSW_CanFamBas_1.0X123,643,041 - 123,657,679 (-)NCBI
UU_Cfam_GSD_1.0X123,404,813 - 123,419,460 (-)NCBI
G6PD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX125,025,257 - 125,041,033 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X125,029,147 - 125,041,040 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X143,553,693 - 143,556,137 (+)NCBISscrofa10.2Sscrofa10.2susScr3
G6PD
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X128,768,028 - 128,788,366 (-)NCBI
ChlSab1.1 EnsemblX128,770,268 - 128,786,961 (-)Ensembl
G6pd
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624946989,376 - 1,001,787 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005340657   ⟹   XP_005340714
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X119,532,130 - 119,548,019 (-)NCBI
SpeTri2.0NW_0049368091,269,901 - 1,285,853 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021720426   ⟹   XP_021576101
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_0049368091,269,900 - 1,284,590 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021720427   ⟹   XP_021576102
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_0049368091,269,900 - 1,284,590 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005340714 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005340714   ⟸   XM_005340657
- UniProtKB: I3N7W5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021576102   ⟸   XM_021720427
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_021576101   ⟸   XM_021720426
- Peptide Label: isoform X2
- Sequence:
Protein Domains
G6PD_C   G6PD_N


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000021077 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000020461 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000025403 UniProtKB/TrEMBL
InterPro G6P_DH UniProtKB/TrEMBL
  G6P_DH_AS UniProtKB/TrEMBL
  G6P_DH_C UniProtKB/TrEMBL
  G6P_DH_NAD-bd UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
NCBI Gene G6pd ENTREZGENE
PANTHER PTHR23429 UniProtKB/TrEMBL
Pfam G6PD_C UniProtKB/TrEMBL
  G6PD_N UniProtKB/TrEMBL
PIRSF G6PD UniProtKB/TrEMBL
PRINTS G6PDHDRGNASE UniProtKB/TrEMBL
PROSITE G6P_DEHYDROGENASE UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
TIGRFAMs zwf UniProtKB/TrEMBL
UniProt I3N7W5 ENTREZGENE, UniProtKB/TrEMBL