Maob (monoamine oxidase B) - Rat Genome Database

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Gene: Maob (monoamine oxidase B) Ictidomys tridecemlineatus
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Symbol: Maob
Name: monoamine oxidase B
RGD ID: 12601199
Description: ENCODES a protein that exhibits flavin adenine dinucleotide binding (ortholog); identical protein binding (ortholog); primary methylamine oxidase activity (ortholog); INVOLVED IN negative regulation of serotonin secretion (ortholog); phenylethylamine catabolic process (ortholog); positive regulation of dopamine metabolic process (ortholog); PARTICIPATES IN citalopram pharmacodynamics pathway; citalopram pharmacokinetics pathway; Parkinson's disease pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Amyloid Plaques (ortholog); autistic disorder (ortholog); FOUND IN dendrite (ortholog); mitochondrial outer membrane (ortholog); neuronal cell body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: amine oxidase [flavin-containing] B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X30,066,432 - 30,229,771 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365029,907,180 - 10,014,773 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365029,907,181 - 10,014,756 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Maob
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X30,066,432 - 30,229,771 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365029,907,180 - 10,014,773 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365029,907,181 - 10,014,756 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAOB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X43,766,610 - 43,882,450 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX43,766,610 - 43,882,450 (-)EnsemblGRCh38hg38GRCh38
GRCh37X43,625,857 - 43,741,696 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X43,510,801 - 43,626,665 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X43,382,111 - 43,497,935NCBI
CeleraX47,765,631 - 47,881,481 (-)NCBICelera
Cytogenetic MapXp11.3NCBI
HuRefX41,355,388 - 41,470,732 (-)NCBIHuRef
CHM1_1X43,659,020 - 43,774,882 (-)NCBICHM1_1
T2T-CHM13v2.0X43,172,827 - 43,288,647 (-)NCBIT2T-CHM13v2.0
Maob
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X16,575,520 - 16,683,605 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX16,575,521 - 16,683,605 (-)EnsemblGRCm39 Ensembl
GRCm38X16,709,281 - 16,817,366 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX16,709,282 - 16,817,366 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X16,286,407 - 16,394,492 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X15,866,241 - 15,974,323 (-)NCBIMGSCv36mm8
CeleraX14,324,831 - 14,433,074 (-)NCBICelera
Cytogenetic MapXA1.2NCBI
cM MapX11.88NCBI
Maob
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X8,490,405 - 8,594,065 (+)NCBIGRCr8
mRatBN7.2X5,907,327 - 6,010,996 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX5,907,266 - 6,011,003 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX5,962,563 - 6,066,216 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X9,438,380 - 9,542,028 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X5,758,453 - 5,862,143 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X6,430,694 - 6,533,520 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX6,430,594 - 6,533,534 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X7,249,779 - 7,352,270 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X17,553,529 - 17,657,852 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X17,606,846 - 17,711,170 (+)NCBI
CeleraX6,397,919 - 6,500,914 (+)NCBICelera
Cytogenetic MapXq11NCBI
Maob
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555164,328,476 - 4,472,593 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555164,328,286 - 4,473,419 (+)NCBIChiLan1.0ChiLan1.0
MAOB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X45,416,758 - 45,532,609 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X45,420,131 - 45,535,938 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X36,217,710 - 36,333,516 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X44,042,000 - 44,157,846 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX44,042,000 - 44,157,941 (-)Ensemblpanpan1.1panPan2
MAOB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X37,765,810 - 37,883,955 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX37,765,813 - 37,883,955 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX24,993,868 - 25,112,008 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X37,854,043 - 37,972,251 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX37,854,043 - 37,972,306 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X37,895,301 - 38,013,405 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X37,878,280 - 37,996,408 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X37,973,208 - 38,091,371 (-)NCBIUU_Cfam_GSD_1.0
MAOB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX39,025,970 - 39,144,345 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X39,025,973 - 39,144,389 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X43,355,507 - 43,474,320 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MAOB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X40,936,789 - 41,054,547 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX40,936,711 - 41,054,641 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660766,156,035 - 6,274,102 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Maob
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476211,584,825 - 11,720,506 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476211,584,925 - 11,720,273 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000004988   ⟹   ENSSTOP00000004476
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365029,907,180 - 10,014,773 (-)Ensembl
RefSeq Acc Id: XM_005323983   ⟹   XP_005324040
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X30,066,432 - 30,174,146 (-)NCBI
SpeTri2.0NW_0049365029,907,181 - 10,014,756 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040275805   ⟹   XP_040131739
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X30,066,432 - 30,229,771 (-)NCBI
Protein Sequences
Protein RefSeqs XP_005324040 (Get FASTA)   NCBI Sequence Viewer  
  XP_040131739 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000004476.3
GenBank Protein KAG3271973 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005324040   ⟸   XM_005323983
- Peptide Label: isoform X2
- UniProtKB: I3M590 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040131739   ⟸   XM_040275805
- Peptide Label: isoform X1
Ensembl Acc Id: ENSSTOP00000004476   ⟸   ENSSTOT00000004988
Protein Domains
Amine oxidase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000004985 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000004988.3 UniProtKB/TrEMBL
Gene3D-CATH 3.50.50.60 UniProtKB/TrEMBL
  3.90.660.10 UniProtKB/TrEMBL
  6.10.250.130 UniProtKB/TrEMBL
InterPro Amino_oxidase UniProtKB/TrEMBL
  FAD/NAD-bd_sf UniProtKB/TrEMBL
  Flavin_amine_oxidase UniProtKB/TrEMBL
  Flavin_MAO UniProtKB/TrEMBL
NCBI Gene Maob ENTREZGENE
PANTHER AMINE OXIDASE UniProtKB/TrEMBL
  AMINE OXIDASE [FLAVIN-CONTAINING] B UniProtKB/TrEMBL
Pfam Amino_oxidase UniProtKB/TrEMBL
PRINTS AMINEOXDASEF UniProtKB/TrEMBL
Superfamily-SCOP FAD-linked reductases, C-terminal domain UniProtKB/TrEMBL
  SSF51905 UniProtKB/TrEMBL
UniProt I3M590 ENTREZGENE, UniProtKB/TrEMBL