Tro (trophinin) - Rat Genome Database

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Gene: Tro (trophinin) Ictidomys tridecemlineatus
Analyze
Symbol: Tro
Name: trophinin
RGD ID: 12577575
Description: INVOLVED IN negative regulation of cell growth (ortholog); ASSOCIATED WITH autistic disorder (ortholog); autosomal hemophilia A (ortholog); Cornelia de Lange syndrome 2 (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC101976785; trophinin, transcript variant X1; trophinin, transcript variant X2; trophinin, transcript variant X3; trophinin, transcript variant X4; trophinin, transcript variant X5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X39,400,999 - 39,412,531 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049367511,740,804 - 1,752,256 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Tro
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X39,400,999 - 39,412,531 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049367511,740,804 - 1,752,256 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRO
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X54,920,824 - 54,931,431 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX54,920,462 - 54,931,431 (+)EnsemblGRCh38hg38GRCh38
GRCh37X54,947,257 - 54,957,864 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X54,963,974 - 54,974,589 (+)NCBINCBI36Build 36hg18NCBI36
CeleraX58,782,397 - 58,793,012 (+)NCBICelera
Cytogenetic MapXp11.21NCBI
HuRefX51,998,723 - 52,009,749 (+)NCBIHuRef
CHM1_1X54,937,045 - 54,947,913 (+)NCBICHM1_1
T2T-CHM13v2.0X54,213,910 - 54,224,559 (+)NCBIT2T-CHM13v2.0
Tro
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X149,427,706 - 149,440,579 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX149,428,300 - 149,440,579 (-)EnsemblGRCm39 Ensembl
GRCm38X150,644,710 - 150,657,583 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX150,645,304 - 150,657,583 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X147,079,846 - 147,091,979 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X145,986,019 - 145,998,115 (-)NCBIMGSCv36mm8
CeleraX133,755,638 - 133,767,712 (+)NCBICelera
Cytogenetic MapXF3NCBI
cM MapX68.46NCBI
Tro
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X22,990,922 - 23,001,955 (-)NCBIGRCr8
mRatBN7.2X19,563,395 - 19,574,507 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX19,563,517 - 19,572,953 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0X23,079,809 - 23,090,912 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X23,502,729 - 23,511,435 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
CeleraX19,834,549 - 19,843,753 (-)NCBICelera
Cytogenetic MapXq12NCBI
Tro
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554752,266,522 - 2,278,016 (+)NCBIChiLan1.0ChiLan1.0
TRO
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X56,316,789 - 56,327,602 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X56,320,457 - 56,331,209 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X47,131,249 - 47,142,012 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X55,362,063 - 55,373,560 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX55,363,522 - 55,373,467 (+)Ensemblpanpan1.1panPan2
TRO
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X46,566,844 - 46,617,430 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX37,942,110 - 37,951,258 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X46,895,135 - 46,904,283 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X46,404,891 - 46,414,038 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X46,871,465 - 46,880,614 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X46,813,740 - 46,822,888 (+)NCBIUU_Cfam_GSD_1.0
TRO
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX47,759,334 - 47,772,014 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X47,759,334 - 47,772,014 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X53,700,769 - 53,708,135 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103232030
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X51,001,421 - 51,015,299 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX51,005,208 - 51,013,942 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660864,976,998 - 4,989,915 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tro
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624910291,559 - 303,561 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624910291,820 - 303,686 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_021719776   ⟹   XP_021575451
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X39,400,999 - 39,412,531 (+)NCBI
SpeTri2.0NW_0049367511,740,804 - 1,752,256 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021719777   ⟹   XP_021575452
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X39,401,090 - 39,412,531 (+)NCBI
SpeTri2.0NW_0049367511,740,880 - 1,752,256 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021719779   ⟹   XP_021575454
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X39,400,999 - 39,411,946 (+)NCBI
SpeTri2.0NW_0049367511,740,804 - 1,751,727 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021719780   ⟹   XP_021575455
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X39,400,999 - 39,411,888 (+)NCBI
SpeTri2.0NW_0049367511,740,804 - 1,751,739 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040281338   ⟹   XP_040137272
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X39,401,098 - 39,412,531 (+)NCBI
RefSeq Acc Id: XP_021575451   ⟸   XM_021719776
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_021575455   ⟸   XM_021719780
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_021575454   ⟸   XM_021719779
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_021575452   ⟸   XM_021719777
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_040137272   ⟸   XM_040281338
- Peptide Label: isoform X2
Protein Domains
MAGE


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000020140 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000021745.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.1200 UniProtKB/TrEMBL
  1.10.10.1210 UniProtKB/TrEMBL
InterPro MAGE UniProtKB/TrEMBL
  MAGE_WH1 UniProtKB/TrEMBL
  MAGE_WH2 UniProtKB/TrEMBL
  MHD_dom UniProtKB/TrEMBL
NCBI Gene LOC101976785 ENTREZGENE
PANTHER PTHR11736 UniProtKB/TrEMBL
  TROPHININ UniProtKB/TrEMBL
Pfam MAGE UniProtKB/TrEMBL
PROSITE MAGE UniProtKB/TrEMBL
SMART MAGE UniProtKB/TrEMBL
UniProt I3NHK4_ICTTR UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-07-13 Tro  trophinin  LOC101976785    Symbol and/or name change 5135510 APPROVED