TRO (trophinin) - Rat Genome Database

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Gene: TRO (trophinin) Pan paniscus
Analyze
Symbol: TRO
Name: trophinin
RGD ID: 11813522
Description: INVOLVED IN negative regulation of cell growth (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Cornelia de Lange syndrome 2 (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC100976284
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X56,316,789 - 56,327,602 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X56,320,457 - 56,331,209 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X47,131,249 - 47,142,012 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X55,362,063 - 55,373,560 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX55,363,522 - 55,373,467 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
TRO
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X56,316,789 - 56,327,602 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X56,320,457 - 56,331,209 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X47,131,249 - 47,142,012 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X55,362,063 - 55,373,560 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX55,363,522 - 55,373,467 (+)Ensemblpanpan1.1panPan2
TRO
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X54,920,824 - 54,931,431 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX54,920,462 - 54,931,431 (+)EnsemblGRCh38hg38GRCh38
GRCh37X54,947,257 - 54,957,864 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X54,963,974 - 54,974,589 (+)NCBINCBI36Build 36hg18NCBI36
CeleraX58,782,397 - 58,793,012 (+)NCBICelera
Cytogenetic MapXp11.21NCBI
HuRefX51,998,723 - 52,009,749 (+)NCBIHuRef
CHM1_1X54,937,045 - 54,947,913 (+)NCBICHM1_1
T2T-CHM13v2.0X54,213,910 - 54,224,559 (+)NCBIT2T-CHM13v2.0
Tro
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X149,427,706 - 149,440,579 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX149,428,300 - 149,440,579 (-)EnsemblGRCm39 Ensembl
GRCm38X150,644,710 - 150,657,583 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX150,645,304 - 150,657,583 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X147,079,846 - 147,091,979 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X145,986,019 - 145,998,115 (-)NCBIMGSCv36mm8
CeleraX133,755,638 - 133,767,712 (+)NCBICelera
Cytogenetic MapXF3NCBI
cM MapX68.46NCBI
Tro
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X22,990,922 - 23,001,955 (-)NCBIGRCr8
mRatBN7.2X19,563,395 - 19,574,507 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX19,563,517 - 19,572,953 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0X23,079,809 - 23,090,912 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X23,502,729 - 23,511,435 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
CeleraX19,834,549 - 19,843,753 (-)NCBICelera
Cytogenetic MapXq12NCBI
Tro
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554752,266,522 - 2,278,016 (+)NCBIChiLan1.0ChiLan1.0
TRO
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X46,566,844 - 46,617,430 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX37,942,110 - 37,951,258 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X46,895,135 - 46,904,283 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X46,404,891 - 46,414,038 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X46,871,465 - 46,880,614 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X46,813,740 - 46,822,888 (+)NCBIUU_Cfam_GSD_1.0
Tro
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X39,400,999 - 39,412,531 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049367511,740,804 - 1,752,256 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRO
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX47,759,334 - 47,772,014 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X47,759,334 - 47,772,014 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X53,700,769 - 53,708,135 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103232030
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X51,001,421 - 51,015,299 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX51,005,208 - 51,013,942 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660864,976,998 - 4,989,915 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tro
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624910291,559 - 303,561 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624910291,820 - 303,686 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000053572   ⟹   ENSPPAP00000030709
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX55,363,522 - 55,373,467 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000053606   ⟹   ENSPPAP00000030742
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX55,363,522 - 55,373,149 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000053610   ⟹   ENSPPAP00000030746
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX55,363,522 - 55,373,149 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000053615   ⟹   ENSPPAP00000030751
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX55,363,820 - 55,373,467 (+)Ensembl
RefSeq Acc Id: XM_014343462   ⟹   XP_014198948
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X56,316,789 - 56,327,201 (+)NCBI
NHGRI_mPanPan1X56,320,463 - 56,331,209 (+)NCBI
Mhudiblu_PPA_v0X47,131,254 - 47,142,007 (+)NCBI
PanPan1.1X55,362,063 - 55,373,560 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034950712   ⟹   XP_034806603
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X56,316,849 - 56,327,201 (+)NCBI
NHGRI_mPanPan1X56,320,463 - 56,331,209 (+)NCBI
Mhudiblu_PPA_v0X47,131,254 - 47,142,007 (+)NCBI
RefSeq Acc Id: XM_034950714   ⟹   XP_034806605
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X56,316,789 - 56,327,602 (+)NCBI
NHGRI_mPanPan1X56,320,458 - 56,331,209 (+)NCBI
Mhudiblu_PPA_v0X47,131,250 - 47,142,012 (+)NCBI
RefSeq Acc Id: XM_055106253   ⟹   XP_054962228
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X56,317,113 - 56,327,201 (+)NCBI
NHGRI_mPanPan1X56,320,722 - 56,331,209 (+)NCBI
RefSeq Acc Id: XM_055106254   ⟹   XP_054962229
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X56,316,853 - 56,327,201 (+)NCBI
NHGRI_mPanPan1X56,320,470 - 56,331,209 (+)NCBI
RefSeq Acc Id: XM_057301062   ⟹   XP_057157045
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X56,316,851 - 56,327,602 (+)NCBI
NHGRI_mPanPan1X56,320,457 - 56,331,209 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_014198948   ⟸   XM_014343462
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_034806605   ⟸   XM_034950714
- Peptide Label: isoform X3
- UniProtKB: A0A2R9BM79 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034806603   ⟸   XM_034950712
- Peptide Label: isoform X1
RefSeq Acc Id: ENSPPAP00000030746   ⟸   ENSPPAT00000053610
RefSeq Acc Id: ENSPPAP00000030751   ⟸   ENSPPAT00000053615
RefSeq Acc Id: ENSPPAP00000030742   ⟸   ENSPPAT00000053606
RefSeq Acc Id: ENSPPAP00000030709   ⟸   ENSPPAT00000053572
RefSeq Acc Id: XP_054962229   ⟸   XM_055106254
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054962228   ⟸   XM_055106253
- Peptide Label: isoform X1
RefSeq Acc Id: XP_057157045   ⟸   XM_057301062
- Peptide Label: isoform X3
- UniProtKB: A0A2R9BM79 (UniProtKB/TrEMBL)
Protein Domains
MAGE


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000038303 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000053572.1 UniProtKB/TrEMBL
  ENSPPAT00000053606.1 UniProtKB/TrEMBL
  ENSPPAT00000053610.1 UniProtKB/TrEMBL
  ENSPPAT00000053615.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.1200 UniProtKB/TrEMBL
  1.10.10.1210 UniProtKB/TrEMBL
InterPro MAGE UniProtKB/TrEMBL
  MAGE_WH1 UniProtKB/TrEMBL
  MAGE_WH2 UniProtKB/TrEMBL
  MHD_dom UniProtKB/TrEMBL
NCBI Gene LOC100976284 ENTREZGENE
PANTHER PTHR11736 UniProtKB/TrEMBL
  TROPHININ UniProtKB/TrEMBL
Pfam MAGE UniProtKB/TrEMBL
PROSITE MAGE UniProtKB/TrEMBL
SMART MAGE UniProtKB/TrEMBL
Superfamily-SCOP Pentapeptide repeat-like UniProtKB/TrEMBL
UniProt A0A2R9BM77_PANPA UniProtKB/TrEMBL
  A0A2R9BM79 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BMW0_PANPA UniProtKB/TrEMBL
  A0A2R9BW42_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-07-01 TRO  trophinin  LOC100976284  trophinin  Symbol and/or name change 5135510 APPROVED