Glis3 (GLIS family zinc finger 3) - Rat Genome Database

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Gene: Glis3 (GLIS family zinc finger 3) Ictidomys tridecemlineatus
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Symbol: Glis3
Name: GLIS family zinc finger 3
RGD ID: 12561087
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); transcription by RNA polymerase II (ortholog); ASSOCIATED WITH angle-closure glaucoma (ortholog); aniridia (ortholog); chromosome 9p deletion syndrome (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC110598015; uncharacterized LOC110598015; zinc finger protein GLIS3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947139,885,832 - 140,319,439 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936503853,436 - 1,287,160 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936503989,817 - 1,283,781 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IEA)

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Glis3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947139,885,832 - 140,319,439 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936503853,436 - 1,287,160 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936503989,817 - 1,283,781 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GLIS3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3893,824,127 - 4,490,465 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl93,824,127 - 4,348,392 (-)EnsemblGRCh38hg38GRCh38
GRCh3793,824,127 - 4,300,068 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3693,814,128 - 4,290,035 (-)NCBINCBI36Build 36hg18NCBI36
Build 3493,817,676 - 4,142,183NCBI
Celera93,742,092 - 4,217,855 (-)NCBICelera
Cytogenetic Map9p24.2NCBI
HuRef93,779,368 - 4,255,081 (-)NCBIHuRef
CHM1_193,824,581 - 4,300,359 (-)NCBICHM1_1
T2T-CHM13v2.093,828,153 - 4,494,104 (-)NCBIT2T-CHM13v2.0
Glis3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391928,236,251 - 28,657,684 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1928,236,251 - 28,657,477 (-)EnsemblGRCm39 Ensembl
GRCm381928,258,851 - 28,680,265 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1928,258,851 - 28,680,077 (-)EnsemblGRCm38mm10GRCm38
MGSCv371928,336,938 - 28,754,567 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361928,328,970 - 28,606,417 (-)NCBIMGSCv36mm8
Celera1929,038,139 - 29,454,917 (-)NCBICelera
Cytogenetic Map19C1NCBI
cM Map1922.88NCBI
Glis3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81235,389,567 - 235,809,416 (-)NCBIGRCr8
mRatBN7.21225,976,029 - 226,395,849 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1225,976,326 - 226,395,899 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01246,380,816 - 246,564,385 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1246,380,889 - 246,785,360 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01253,622,178 - 254,039,761 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41231,881,983 - 232,292,288 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.41232,291,906 - 232,306,168 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1223,130,737 - 223,177,831 (-)NCBICelera
Cytogenetic Map1q52NCBI
Glis3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554348,145,053 - 8,573,537 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554348,140,965 - 8,581,889 (-)NCBIChiLan1.0ChiLan1.0
GLIS3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v211120,266,621 - 120,758,261 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan19120,272,559 - 120,764,199 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v093,633,416 - 4,125,420 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.193,823,567 - 4,314,140 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl93,827,712 - 4,300,658 (-)Ensemblpanpan1.1panPan2
GLIS3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1192,278,521 - 92,824,303 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl192,282,164 - 92,734,468 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha192,750,809 - 93,296,691 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0192,826,097 - 93,377,711 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl192,829,077 - 93,272,131 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1192,463,220 - 93,009,736 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0192,186,805 - 92,732,955 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0192,951,661 - 93,498,143 (-)NCBIUU_Cfam_GSD_1.0
GLIS3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1217,629,883 - 218,117,267 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11217,572,604 - 218,117,629 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21243,782,562 - 243,981,149 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GLIS3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11275,244,685 - 75,726,554 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603863,577,873 - 64,060,383 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Glis3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247368,555,916 - 9,004,996 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247368,552,143 - 9,030,122 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000000301   ⟹   ENSSTOP00000000269
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936503853,436 - 1,287,160 (+)Ensembl
RefSeq Acc Id: XM_021725602   ⟹   XP_021581277
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947139,885,832 - 140,319,439 (-)NCBI
SpeTri2.0NW_004936503989,817 - 1,283,781 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040285710   ⟹   XP_040141644
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947139,885,832 - 140,319,295 (-)NCBI
RefSeq Acc Id: XM_040285711   ⟹   XP_040141645
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947139,885,832 - 140,317,866 (-)NCBI
RefSeq Acc Id: XM_040285712   ⟹   XP_040141646
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947139,885,832 - 140,319,293 (-)NCBI
RefSeq Acc Id: XM_040285713   ⟹   XP_040141647
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947139,885,832 - 140,319,295 (-)NCBI
RefSeq Acc Id: XM_040285714   ⟹   XP_040141648
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947139,885,832 - 140,319,295 (-)NCBI
RefSeq Acc Id: XM_040285715   ⟹   XP_040141649
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947139,885,832 - 140,306,209 (-)NCBI
RefSeq Acc Id: XP_021581277   ⟸   XM_021725602
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_040141648   ⟸   XM_040285714
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040141647   ⟸   XM_040285713
- Peptide Label: isoform X2
RefSeq Acc Id: XP_040141644   ⟸   XM_040285710
- Peptide Label: isoform X1
- UniProtKB: I3LWC5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040141646   ⟸   XM_040285712
- Peptide Label: isoform X1
- UniProtKB: I3LWC5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040141645   ⟸   XM_040285711
- Peptide Label: isoform X1
- UniProtKB: I3LWC5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040141649   ⟸   XM_040285715
- Peptide Label: isoform X3
Ensembl Acc Id: ENSSTOP00000000269   ⟸   ENSSTOT00000000301
Protein Domains
C2H2-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000000302 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000000301.3 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro GLI-like UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene Glis3 ENTREZGENE
PANTHER PTHR45718 UniProtKB/TrEMBL
  PTHR45718:SF1 UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt I3LWC5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-25 Glis3  GLIS family zinc finger 3  LOC110598015  uncharacterized LOC110598015  Data merged from RGD:12976412 737654 PROVISIONAL