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Gene: Glis3 (GLIS family zinc finger 3) Mus musculus
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Symbol: Glis3
Name: GLIS family zinc finger 3
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; and transcription by RNA polymerase II. Localizes to the nucleus. Used to study neonatal diabetes mellitus with congenital hypothyroidism. Human ortholog(s) of this gene implicated in neonatal diabetes mellitus with congenital hypothyroidism. Is expressed in several structures, including brain ventricular layer; embryo ectoderm; eye; genitourinary system; and limb. Orthologous to human GLIS3 (GLIS family zinc finger 3).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 4833409N03Rik; E230012L24; E330013K21Rik; GLI-similar 3; Kruppel-like zinc finger protein Glis3; zinc finger protein GLIS3
Orthologs:
Homo sapiens (human) : GLIS3 (GLIS family zinc finger 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Glis3 (GLIS family zinc finger 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Glis3 (GLIS family zinc finger 3)
Pan paniscus (bonobo/pygmy chimpanzee) : GLIS3 (GLIS family zinc finger 3)
Canis lupus familiaris (dog) : GLIS3 (GLIS family zinc finger 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Glis3 (GLIS family zinc finger 3)
Sus scrofa (pig) : GLIS3 (GLIS family zinc finger 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381928,258,851 - 28,680,265 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371928,336,938 - 28,754,567 (-)NCBIGRCm37mm9NCBIm37
MGSCv361928,328,970 - 28,606,417 (-)NCBImm8
Celera1929,038,139 - 29,454,917 (-)NCBICelera
Cytogenetic Map19 C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Glis3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1557009
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-10-22
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.