Gab2 (GRB2 associated binding protein 2) - Rat Genome Database
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Gene: Gab2 (GRB2 associated binding protein 2) Ictidomys tridecemlineatus
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Symbol: Gab2
Name: GRB2 associated binding protein 2
RGD ID: 12545209
Description: ENCODES a protein that exhibits phosphatidylinositol-3,4,5-trisphosphate binding (ortholog); phosphatidylinositol-3,4-bisphosphate binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN cell migration (ortholog); integrin-mediated signaling pathway (ortholog); intracellular signal transduction (ortholog); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; granulocyte-macrophage colony-stimulating factor signaling pathway; interleukin-2 signaling pathway; ASSOCIATED WITH chronic myeloid leukemia (ortholog); melanoma (ortholog); Neoplasm Invasiveness (ortholog); FOUND IN cytoplasm (ortholog); plasma membrane (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: GRB2-associated-binding protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049364986,775,170 - 6,835,680 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

Genomics

Comparative Map Data
Gab2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049364986,775,170 - 6,835,680 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GAB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1178,215,293 - 78,418,348 (-)EnsemblGRCh38hg38GRCh38
GRCh381178,215,293 - 78,417,820 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371177,926,339 - 78,128,866 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh371177,926,336 - 78,128,868 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361177,603,990 - 77,806,414 (-)NCBINCBI36hg18NCBI36
Build 341177,603,989 - 77,806,414NCBI
Celera1175,234,820 - 75,437,334 (-)NCBI
Cytogenetic Map11q14.1NCBI
HuRef1174,223,774 - 74,350,451 (-)NCBIHuRef
CHM1_11177,809,494 - 78,012,010 (-)NCBICHM1_1
Gab2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39796,730,958 - 96,958,158 (+)NCBIGRCm39mm39
GRCm38797,081,751 - 97,308,951 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl797,081,586 - 97,308,946 (+)EnsemblGRCm38mm10GRCm38
MGSCv377104,230,261 - 104,457,461 (+)NCBIGRCm37mm9NCBIm37
MGSCv36796,956,943 - 97,180,228 (+)NCBImm8
MGSCv36786,817,681 - 87,047,535 (+)NCBImm8
Cytogenetic Map7E1NCBI
Gab2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21151,429,844 - 151,625,708 (+)NCBI
Rnor_6.0 Ensembl1162,083,030 - 162,279,727 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01162,082,876 - 162,283,379 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01168,423,264 - 168,486,051 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41154,348,777 - 154,544,906 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11154,427,186 - 154,623,310 (+)NCBI
Celera1149,534,433 - 149,721,184 (+)NCBICelera
Cytogenetic Map1q32NCBI
Gab2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541413,679,588 - 13,751,079 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541413,640,713 - 13,754,401 (+)NCBIChiLan1.0ChiLan1.0
GAB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11176,896,691 - 76,965,955 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1176,896,691 - 76,967,007 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01173,275,360 - 73,478,272 (-)NCBIMhudiblu_PPA_v0panPan3
NARS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2120,277,507 - 20,606,736 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12120,277,707 - 20,413,624 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
GAB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl912,656,882 - 12,851,402 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1912,663,658 - 12,851,423 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2913,937,322 - 14,135,579 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GAB2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1169,422,517 - 69,624,411 (-)NCBI
ChlSab1.1 Ensembl169,424,100 - 69,624,279 (-)Ensembl
Gab2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248631,216,664 - 1,410,934 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_021725131   ⟹   XP_021580806
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_0049364986,775,170 - 6,835,680 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_021580806 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_021580806   ⟸   XM_021725131
- Sequence:
Protein Domains
PH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000003173 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000002830 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000003169 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
NCBI Gene Gab2 ENTREZGENE
Pfam PF00169 UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
SMART SM00233 UniProtKB/TrEMBL
UniProt I3M1S9_ICTTR UniProtKB/TrEMBL