Slc7a10 (solute carrier family 7 member 10)

Gene: Slc7a10 (solute carrier family 7 member 10) Ictidomys tridecemlineatus

Analyze

Symbol:

Slc7a10

Name:

solute carrier family 7 member 10

RGD ID:

12524367

Description:

ENCODES a protein that exhibits L-amino acid transmembrane transporter activity (inferred); neutral L-amino acid transmembrane transporter activity (inferred); transmembrane transporter activity (inferred); INVOLVED IN D-alanine transmembrane transport (ortholog); D-serine transmembrane transport (ortholog); neutral amino acid transport (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); genetic disease (ortholog); hereditary spastic paraplegia 75 (ortholog); FOUND IN apical dendrite (ortholog); neuronal cell body (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

asc-type amino acid transporter 1; solute carrier family 7 member 10, transcript variant X1; solute carrier family 7 member 10, transcript variant X2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	9,056,066 - 9,070,105 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936570	2,575,386 - 2,593,299 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936570	2,575,784 - 2,589,808 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute myeloid leukemia (ISO)

genetic disease (ISO)

hereditary spastic paraplegia 75 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

amino acid transport (IEA)

D-alanine transmembrane transport (IEA,ISO)

D-serine transmembrane transport (IEA,ISO)

glycine transport (IEA)

L-alpha-amino acid transmembrane transport (IEA)

negative regulation of brown fat cell differentiation (IEA)

neutral amino acid transport (IEA,ISO)

positive regulation of synaptic transmission, glycinergic (IEA)

transmembrane transport (IEA)

Cellular Component

apical dendrite (ISO)

membrane (IEA)

neuronal cell body (ISO)

plasma membrane (IEA)

Molecular Function

L-amino acid transmembrane transporter activity (IEA)

neutral L-amino acid transmembrane transporter activity (IEA)

protein binding (ISO)

transmembrane transporter activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Slc7a10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	9,056,066 - 9,070,105 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936570	2,575,386 - 2,593,299 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936570	2,575,784 - 2,589,808 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC7A10
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	33,208,664 - 33,225,850 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	33,208,664 - 33,225,850 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	33,699,570 - 33,716,756 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	38,391,411 - 38,408,548 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	38,391,410 - 38,408,548	NCBI
Celera	19	30,393,162 - 30,410,341 (-)	NCBI		Celera
Cytogenetic Map	19	q13.11	NCBI
HuRef	19	30,201,437 - 30,218,673 (-)	NCBI		HuRef
CHM1_1	19	33,700,507 - 33,717,756 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	35,727,305 - 35,744,598 (-)	NCBI		T2T-CHM13v2.0

Slc7a10
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	34,885,520 - 34,900,539 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	34,885,810 - 34,900,539 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	35,186,095 - 35,201,116 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	35,186,385 - 35,201,114 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	35,971,404 - 35,986,130 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	34,895,178 - 34,909,870 (+)	NCBI		MGSCv36	mm8
Celera	7	30,326,223 - 30,340,996 (+)	NCBI		Celera
Cytogenetic Map	7	B2	NCBI
cM Map	7	21.13	NCBI

Slc7a10
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	96,966,030 - 96,982,020 (+)	NCBI		GRCr8
mRatBN7.2	1	87,829,084 - 87,845,073 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	87,829,175 - 87,845,071 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	93,235,422 - 93,251,543 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	101,701,408 - 101,717,518 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	94,993,724 - 95,009,846 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	91,432,952 - 91,448,566 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	91,433,030 - 91,448,564 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	92,563,339 - 92,579,264 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	87,695,658 - 87,711,595 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	87,773,768 - 87,789,704 (+)	NCBI
Celera	1	82,180,310 - 82,195,867 (+)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

Slc7a10
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955468	2,968,720 - 2,984,125 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955468	2,968,720 - 2,984,101 (-)	NCBI	ChiLan1.0	ChiLan1.0

SLC7A10
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	39,181,203 - 39,198,257 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	41,180,514 - 41,197,587 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	30,130,974 - 30,148,055 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	38,876,098 - 38,893,018 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	38,876,098 - 38,893,018 (-)	Ensembl	panpan1.1		panPan2

SLC7A10
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	118,908,087 - 118,923,034 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	118,907,184 - 118,923,215 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	118,308,994 - 118,323,875 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	119,506,650 - 119,521,536 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	119,506,605 - 119,521,705 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	119,067,024 - 119,081,913 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	118,693,471 - 118,708,387 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	119,752,439 - 119,767,380 (+)	NCBI		UU_Cfam_GSD_1.0

SLC7A10
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	43,002,431 - 43,017,554 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	43,002,427 - 43,017,605 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	38,579,833 - 38,595,001 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LOC103234456
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	28,249,906 - 28,267,262 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	28,249,278 - 28,267,221 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	5,886,131 - 5,903,492 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc7a10
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624794	9,876,606 - 9,891,366 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624794	9,876,197 - 9,891,398 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005330633	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021730056	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010004409	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000009451 ⟹ ENSSTOP00000008477

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936570	2,575,386 - 2,589,588 (+)	Ensembl

RefSeq Acc Id:

ENSSTOT00000039404 ⟹ ENSSTOP00000032335

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936570	2,575,762 - 2,593,299 (+)	Ensembl

RefSeq Acc Id:

XM_005330633 ⟹ XP_005330690

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024409349	9,056,066 - 9,070,105 (-)	NCBI
SpeTri2.0	NW_004936570	2,575,784 - 2,589,808 (+)	NCBI

Sequence:

show sequence

CCCGCGCCAGCGCATGCGCCCGCCTGTGGGCGCTGTCCCGGCTGCGAGGGCTGCGAGCGCACCG
ACAGACAGACCGACCGACGGACCGGCAGTCCGCCGGACAGACAGCGCAGGGTGCCGGGACGTGG
CGGGACAGCGATATGACCGGCCACATACAACAGCCAAGTGGGCGCGGGAACCCCGGTCCTGCGC
CCTCGCCTTCCCCCGGCCCGGGCCCCGGCCCTGGCGCCTCGGAGAGGGTAGCGCTCAAGAAGGA
GATCGGACTGGTGAGCGCCTGTACCATCATCGTCGGGAACATCATTGGCTCTGGCATCTTCATC
TCACCCAAGGGTGTCCTTGAGCACTCAGGCTCCGTGGGTCTGGCCCTCTTCGTCTGGGTCCTGG
GTGGGGGCGTGACAGCTCTGGGCTCTCTCTGCTATGCAGAGCTGGGAGTTGCCATCCCCAAGTC
CGGCGGGGACTACGCCTATGTCACGGAGATCTTCGGGGGCCTGGCTGGATTCCTGCTGCTCTGG
AGTGCCGTCCTCATCATGTACCCCACCAGCCTGGCTGTCATCTCCATGACCTTCTCCAACTACG
TGCTGCAACCTGTGTTCCCCAACTGCATCCCCCCAGCTACGGCCTCTCGTGTGCTCTCCATGGC
CTGCCTGATGCTCCTGACGTGGGTGAATGGCTCCAGTGTGCGCTGGGCCACACGCATCCAGGAC
ATCTTCACGGGTGGGAAGCTGCTGGCCCTGTCCCTCATCATTGGCATTGGCTTTGTCCAGATCT
TCCAAGGACATTTCGAGGAACTGAGGCCCAGCAATGCCTTCACCTTCTGGATGACGCCCTCTGT
GGGTCACCTGGCCCTGGCCTTTCTCCAGGGCTCCTTTGCCTTCAGCGGCTGGAACTTCCTCAAC
TATGTCACCGAGGAGCTGGTTGACCCTCGCAAGAACCTACCTCGTGCCATCTTCATCTCTATCC
CTCTGGTGACCTTCGTGTACACGTTCACCAACGTTGCCTACTTCACCGCCATGTCACCCCAAGA
GCTGCTGTCTTCTAACGCAGTGGCTGTGACCTTCGGGGAGAAGCTGCTGGGCTACTTTGCATGG
GTCATGCCCGTCTCCGTGGCTCTTTCCACTTTTGGAGGGATCAATGGCTACCTGTTCACCTCCT
CCAGGCTGTGCTTCTCTGGAGCCCGAGAGGGGCACTTGCCCAGCCTGCTAGCAATGATCCATGT
CAGACGCTGTACCCCCATCCCTGCCCTCCTTGTCTGTTGCGGGGCCACCGCGGTGATCATGCTT
GTGGGAGACACGTACACACTCATCAACTACGTGTCCTTCATCAACTACCTCTGCTACGGCGTCA
CCATCCTGGGCCTGCTTGTTCTGCGCTGGAGGCGGCCAGCACTCCACAGGCCCATCAAGGTGAA
CCTGCTGGTCCCGGTGGCGTACCTGGTATTCTGGGCATTCCTGCTGGTCTTCAGCTTCATCTCG
GAGCCCATGGTCTGTGGGGTTGGCGTCATCATCATCCTCACAGGGGTGCCCATTTTCTTCCTGG
GAGTGTTCTGGAGGAGGAAACCAAAGTGTGTACACAGACTCACAGAGTCCATGACACGCTGGGG
CCAGGAGTTGTGTTTCGTGGTTTACCCCCAGTGCTCCCCCGAGGAGGAGGAGGAAAATGGCCCC
TACCAGCCCTTCCCACTGCCGGCCACGGACAAGCCCTTAAAGACACAATGAGACATTGGTAGAG
ACTGAAGCAGCTGTTTCTGTTTACATGTTGTTTATTGAGGAGGTGTTTTTGCAAAATCTTTTTT
TTTTTTTTCCTGGAAAGAAGAGATATGACTCTTAGAGGCCTGTCGTAAGGAAGCCCAGACAAGG
TGGACGGGGGGTTTCCTGCCTTAGCACTGCCCTGCTAGCTTTTTCTGAAAAGGCCTACAAATAA
ACAGGGCTGGTTGTT

hide sequence

Protein Sequences


Protein RefSeqs	XP_005330690	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000008477.3
	ENSSTOP00000032335.1
GenBank Protein	KAG3255790	(Get FASTA)	NCBI Sequence Viewer
	KAG3255791	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005330690 ⟸ XM_005330633

- UniProtKB:

A0A287DFM7 (UniProtKB/TrEMBL), I3MDK7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MTGHIQQPSGRGNPGPAPSPSPGPGPGPGASERVALKKEIGLVSACTIIVGNIIGSGIFISPKG
VLEHSGSVGLALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVL
IMYPTSLAVISMTFSNYVLQPVFPNCIPPATASRVLSMACLMLLTWVNGSSVRWATRIQDIFTG
GKLLALSLIIGIGFVQIFQGHFEELRPSNAFTFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTE
ELVDPRKNLPRAIFISIPLVTFVYTFTNVAYFTAMSPQELLSSNAVAVTFGEKLLGYFAWVMPV
SVALSTFGGINGYLFTSSRLCFSGAREGHLPSLLAMIHVRRCTPIPALLVCCGATAVIMLVGDT
YTLINYVSFINYLCYGVTILGLLVLRWRRPALHRPIKVNLLVPVAYLVFWAFLLVFSFISEPMV
CGVGVIIILTGVPIFFLGVFWRRKPKCVHRLTESMTRWGQELCFVVYPQCSPEEEEENGPYQPF
PLPATDKPLKTQ

hide sequence

RefSeq Acc Id:

ENSSTOP00000008477 ⟸ ENSSTOT00000009451

RefSeq Acc Id:

ENSSTOP00000032335 ⟸ ENSSTOT00000039404

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000009450	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000009451.3	UniProtKB/TrEMBL
	ENSSTOT00000039404.1	UniProtKB/TrEMBL
Gene3D-CATH	Amino acid/polyamine transporter I	UniProtKB/TrEMBL
InterPro	AA/rel_permease1	UniProtKB/TrEMBL
NCBI Gene	Slc7a10	ENTREZGENE
PANTHER	AMINO ACID TRANSPORTER	UniProtKB/TrEMBL
	ASC-TYPE AMINO ACID TRANSPORTER 1	UniProtKB/TrEMBL
Pfam	AA_permease_2	UniProtKB/TrEMBL
PIRSF	AA_transporter	UniProtKB/TrEMBL
UniProt	A0A287DFM7	ENTREZGENE, UniProtKB/TrEMBL
	I3MDK7	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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