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Gene: Pcyox1 (prenylcysteine oxidase 1) Ictidomys tridecemlineatus

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Symbol:

Pcyox1

Name:

prenylcysteine oxidase 1

RGD ID:

12509880

Description:

ENCODES a protein that exhibits FAD binding (inferred); oxidoreductase activity (inferred); oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor (inferred); INVOLVED IN chloride transmembrane transport (ortholog); ASSOCIATED WITH Weight Gain (ortholog); FOUND IN lysosome (inferred); very-low-density lipoprotein particle (inferred)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	14,131,693 - 14,148,615 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936491	14,422,638 - 14,439,569 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936491	14,422,683 - 14,439,599 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pcyox1	Squirrel	Weight Gain		ISO	RGD:1350972	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:19030233

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pcyox1	Squirrel	chloride transmembrane transport		ISO	RGD:628652	9068941		RGD	PMID:11716481\|REF_RGD_ID:632356
Pcyox1	Squirrel	prenylated protein catabolic process	involved_in	IEA	PANTHER:PTN000409255	150520179		TreeGrafter	GO_REF:0000118
Pcyox1	Squirrel	prenylated protein catabolic process	involved_in	IEA	UniProtKB:Q9UHG3\|ensembl:ENSP00000387654	150520179		Ensembl	GO_REF:0000107
Pcyox1	Squirrel	prenylcysteine catabolic process	involved_in	IEA	UniRule:UR000356802	150520179		UniProt	GO_REF:0000104
Pcyox1	Squirrel	prenylcysteine catabolic process	acts_upstream_of_or_within	IEA	UniProtKB:Q9CQF9\|ensembl:ENSMUSP00000032065	150520179		Ensembl	GO_REF:0000107
Pcyox1	Squirrel	prenylcysteine catabolic process	involved_in	IEA	UniProtKB:Q9UHG3\|ensembl:ENSP00000387654	150520179		Ensembl	GO_REF:0000107
Pcyox1	Squirrel	prenylcysteine catabolic process	involved_in	IEA	InterPro:IPR010795	150520179		InterPro	GO_REF:0000002

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pcyox1	Squirrel	lysosome	located_in	IEA	UniProtKB:Q9CQF9\|UniProtKB:Q9UHG3\|ensembl:ENSMUSP00000032065\|ensembl:ENSP00000387654	150520179		Ensembl	GO_REF:0000107
Pcyox1	Squirrel	lysosome	located_in	IEA	UniProtKB-SubCell:SL-0158	150520179		UniProt	GO_REF:0000044
Pcyox1	Squirrel	lysosome	located_in	IEA	UniProtKB-KW:KW-0458	150520179		UniProt	GO_REF:0000043
Pcyox1	Squirrel	very-low-density lipoprotein particle	part_of	IEA	UniProtKB:Q9UHG3\|ensembl:ENSP00000387654	150520179		Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Pcyox1	Squirrel	FAD binding	enables	IEA	UniProtKB:Q9UHG3\|ensembl:ENSP00000387654	150520179		Ensembl	GO_REF:0000107
Pcyox1	Squirrel	oxidoreductase activity	enables	IEA	UniProtKB-KW:KW-0560	150520179		UniProt	GO_REF:0000043
Pcyox1	Squirrel	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	enables	IEA	InterPro:IPR010795	150520179		InterPro	GO_REF:0000002
Pcyox1	Squirrel	prenylcysteine oxidase activity	enables	IEA	PANTHER:PTN000409255	150520179		TreeGrafter	GO_REF:0000118
Pcyox1	Squirrel	prenylcysteine oxidase activity	enables	IEA	UniProtKB:Q9CQF9\|UniProtKB:Q9UHG3\|ensembl:ENSMUSP00000032065\|ensembl:ENSP00000387654	150520179		Ensembl	GO_REF:0000107
Pcyox1	Squirrel	prenylcysteine oxidase activity	enables	IEA	UniRule:UR000356802	150520179		UniProt	GO_REF:0000104
Pcyox1	Squirrel	prenylcysteine oxidase activity	enables	IEA	InterPro:IPR017046	150520179		InterPro	GO_REF:0000002
Pcyox1	Squirrel	protein binding	enables	ISO	UniProtKB:O75712\|UniProtKB:Q9Y227	9068941	PMID:33961781	IntAct	PMID:33961781
Pcyox1	Squirrel	protein binding	enables	ISO	UniProtKB:P49639	9068941	PMID:32296183	IntAct	PMID:32296183

PMID:22301074	PMID:30032202

Pcyox1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	14,131,693 - 14,148,615 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936491	14,422,638 - 14,439,569 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936491	14,422,683 - 14,439,599 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PCYOX1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	70,257,915 - 70,281,185 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	70,257,386 - 70,281,185 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	70,485,269 - 70,508,317 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	70,338,797 - 70,360,731 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	70,396,943 - 70,418,866	NCBI
Celera	2	70,335,922 - 70,359,008 (+)	NCBI		Celera
Cytogenetic Map	2	p13.3	NCBI
HuRef	2	70,222,037 - 70,245,162 (+)	NCBI		HuRef
CHM1_1	2	70,414,817 - 70,437,898 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	70,269,656 - 70,292,921 (+)	NCBI		T2T-CHM13v2.0

Pcyox1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	86,362,988 - 86,374,132 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	86,362,988 - 86,374,136 (-)	Ensembl		GRCm39 Ensembl
GRCm38	6	86,386,006 - 86,397,150 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	86,386,006 - 86,397,154 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	86,336,000 - 86,347,144 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	86,352,491 - 86,362,754 (-)	NCBI		MGSCv36	mm8
Celera	6	88,323,385 - 88,334,467 (-)	NCBI		Celera
Cytogenetic Map	6	D1	NCBI
cM Map	6	37.69	NCBI

Pcyox1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	120,389,545 - 120,400,382 (-)	NCBI		GRCr8
mRatBN7.2	4	118,832,114 - 118,842,951 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	118,830,638 - 118,842,951 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	124,304,788 - 124,315,641 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	120,079,535 - 120,090,388 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	118,703,792 - 118,714,645 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	118,187,133 - 118,198,029 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	118,187,134 - 118,198,029 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	182,758,383 - 182,769,279 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	120,569,436 - 120,580,273 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	120,812,433 - 120,824,736 (-)	NCBI
Celera	4	107,803,829 - 107,814,666 (-)	NCBI		Celera
Cytogenetic Map	4	q34	NCBI

Pcyox1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955424	14,855,106 - 14,865,840 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955424	14,854,755 - 14,865,920 (-)	NCBI	ChiLan1.0	ChiLan1.0

PCYOX1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	56,117,040 - 56,139,532 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	56,120,985 - 56,143,461 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	70,313,204 - 70,335,361 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	71,429,520 - 71,449,292 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	71,429,514 - 71,449,292 (+)	Ensembl	panpan1.1		panPan2

PCYOX1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	68,806,611 - 68,825,941 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	68,806,572 - 68,823,291 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	68,694,892 - 68,713,751 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	69,828,762 - 69,847,879 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	69,828,743 - 69,847,878 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	69,546,356 - 69,565,212 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	69,808,868 - 69,828,327 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	70,108,248 - 70,127,207 (+)	NCBI		UU_Cfam_GSD_1.0

PCYOX1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	72,207,408 - 72,223,581 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	72,207,406 - 72,223,605 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	75,478,452 - 75,494,635 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PCYOX1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	36,840,056 - 36,859,114 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	36,841,327 - 36,859,079 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666045	75,151,759 - 75,172,308 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pcyox1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624762	3,167,661 - 3,175,679 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624762	3,164,320 - 3,175,760 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	XM_005322121	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010001352	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000008327 ⟹ ENSSTOP00000007463

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936491	14,422,638 - 14,439,569 (+)	Ensembl

RefSeq Acc Id:

XM_005322121 ⟹ XP_005322178

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024406292	14,131,693 - 14,148,615 (-)	NCBI
SpeTri2.0	NW_004936491	14,422,683 - 14,439,599 (+)	NCBI

Sequence:

show sequence

AGACGCGCCGCTGCGTGGGGACTGCAGGGAACTGGAGGCCGGTTGCTGCGTTTGGGAAGGCCATGGGGCACGTCGCCGGGGAACTCGGCTTGTCGCTGCTGTGGCTGTGGCTGCTGCTGTGCAGCTGG
GGGTGCCTCGGTAGCGCCGAGCTGCGGGCTCCACCGGAGAAGATCGCAATTATTGGAGCTGGAATTGGTGGCACTTCATCAGCCTATTATCTGCGGCAGAAATTTGGGAAAGATGTGAAGATTGACCT
GTTTGAAAGAAAAGAGGTGGGGGGCCGTTTAGCCACCCTGACTGTGGAAGGGCAAGAATATGAGGCAGGAGGTTCTGTTATACATCCTTTAAATCTGCACATGAAGCGTTTTGTCAAAGACCTCGGTC
TCTCCACTGTTCAGGCTTCGGGTGGCCTACTGGGGGTGTACGATGGACAAACTCTGGTGTTTGAGGAGAGCAGCTGGTTTATAATGAACATGATTAAACTAGTTTGGCGCTATGGATTTCAGTCACTC
CGAATGCACATGTGGGTTGAAGATGTGTTGGACAAGTTCATGAGGATCTACCGCTACCAGTCTCATGACTATGCCTTCAGTAGTGTAGAAAAATTACTCCATGCTGTAGGAGGAGATGACTTCCTTGG
GTTGCTTAACCGAACGCTTCATGAAACCTTGCAGAAAGCAGGCTTCTCTGAGAAATTCCTCAATGAAATGATTGCTCCCGTCATGAGGGTCAATTACGGTCAAAGCACAGACATCAATGCCTTTGTGG
GGGCAGTGTCACTGACTGCTGCTGATTCTGGCCTTTGGGCAGTAGAAGGTGGTAATAAACTTGTTTGTTCACGGCTCCTCCAGGCTTCCAAAAGCAATCTTATATCTGGCTCAGTAATGTATATAGAG
AAAACAAGGACCAAGCAGACAGGAAATCCCACAAAGATGTATGAAGTGGTGTACCAAAGTGGATCCGAGACCCACTCAGACTTCTATGACATCGTCTTGGTGGCCACTCCATTGAATCAAAAAATGTC
CAACATTACTTTCCTCAACTTTGATCCTCCAATTGAGGAATTTCATCAGTATTACCAACATATAGTGACAACTTTGGTTAAGGGAGAATTGAATTCAACTGTATTTAGCTCTAGAGCCAAAGATCAGT
TTGGCCTGTCTACAGTTTTGACCACTGATAGTTCAGACCTGTTTATTAACAACGTTGGGATTGTGTCCTCTGTAAGAGAAAAGGACAGTCCTCAACCATCAACAGATGGAACGTATGTTTGGAAGACT
TTTTCCCCAGAAGTTCTTACTAAACAACAAATTTTTAAGCTCTTTTTGTCCTATGATTATGCTGTGAAGAAGTCTTGGCTTGCATATCCTCACTATAAGCCCCCGGAGAAATGTCCCTCCATCATACT
CCATGATCGGCTGTATTACCTCAATGGTATAGAGTTTGCAGCAAGTGCCATGGAAATGAGTGCCATCGCAGCCCATAATGCTGCACTCCTTGCCTATCACCGCTGGAATGGGAACGCAGACATGATTG
ACCAAGATGGCCTCTATGAGAAACTTAAAACGGAGCTATGAAATAACATTCTCGTTTTTCCTCTCCTGGTTCCCCATGAGTACCACTGGCAAAAAAAAAAAAAAAAGAAAAAAAGAAAAA

hide sequence


Protein RefSeqs	XP_005322178	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000007463.3
GenBank Protein	KAG3267145	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005322178 ⟸ XM_005322121

- UniProtKB:

I3MBF5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGHVAGELGLSLLWLWLLLCSWGCLGSAELRAPPEKIAIIGAGIGGTSSAYYLRQKFGKDVKIDLFERKEVGGRLATLTVEGQEYEAGGSVIHPLNLHMKRFVKDLGLSTVQASGGLLGVYDGQTLVF
EESSWFIMNMIKLVWRYGFQSLRMHMWVEDVLDKFMRIYRYQSHDYAFSSVEKLLHAVGGDDFLGLLNRTLHETLQKAGFSEKFLNEMIAPVMRVNYGQSTDINAFVGAVSLTAADSGLWAVEGGNKL
VCSRLLQASKSNLISGSVMYIEKTRTKQTGNPTKMYEVVYQSGSETHSDFYDIVLVATPLNQKMSNITFLNFDPPIEEFHQYYQHIVTTLVKGELNSTVFSSRAKDQFGLSTVLTTDSSDLFINNVGI
VSSVREKDSPQPSTDGTYVWKTFSPEVLTKQQIFKLFLSYDYAVKKSWLAYPHYKPPEKCPSIILHDRLYYLNGIEFAASAMEMSAIAAHNAALLAYHRWNGNADMIDQDGLYEKLKTEL

hide sequence

Ensembl Acc Id:

ENSSTOP00000007463 ⟸ ENSSTOT00000008327

Protein Domains

Prenylcysteine lyase

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000008327	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000008327.3	UniProtKB/TrEMBL
Gene3D-CATH	3.50.50.60	UniProtKB/TrEMBL
InterPro	FAD/NAD-bd_sf	UniProtKB/TrEMBL
	Prenylcys_lyase	UniProtKB/TrEMBL
	Prenylcysteine_Oxase	UniProtKB/TrEMBL
NCBI Gene	Pcyox1	ENTREZGENE
PANTHER	PRENYLCYSTEINE OXIDASE 1	UniProtKB/TrEMBL
	PTHR15944	UniProtKB/TrEMBL
Pfam	NAD_binding_8	UniProtKB/TrEMBL
	Prenylcys_lyase	UniProtKB/TrEMBL
PIRSF	Prenylcysteine_oxidase	UniProtKB/TrEMBL
Superfamily-SCOP	SSF51905	UniProtKB/TrEMBL
UniProt	I3MBF5	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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Imported Disease Annotations - CTD