IZUMO1R (IZUMO1 receptor, JUNO) - Rat Genome Database

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Gene: IZUMO1R (IZUMO1 receptor, JUNO) Canis lupus familiaris
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Symbol: IZUMO1R
Name: IZUMO1 receptor, JUNO
RGD ID: 12372291
Description: ENCODES a protein that exhibits folic acid binding (ortholog); protein binding involved in heterotypic cell-cell adhesion (ortholog); signaling receptor binding (ortholog); INVOLVED IN cell adhesion (ortholog); fusion of sperm to egg plasma membrane involved in single fertilization (ortholog); single fertilization (ortholog); ASSOCIATED WITH intellectual disability (ortholog); FOUND IN plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: folate receptor 4 (delta) homolog; folate receptor 4, delta (putative); FOLR4; sperm-egg fusion protein Juno
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1216,597,039 - 6,599,484 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl216,596,141 - 6,599,840 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha216,607,027 - 6,609,932 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0216,777,138 - 6,780,041 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl216,777,062 - 6,784,386 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1216,557,952 - 6,560,822 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0216,626,822 - 6,629,712 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0216,676,910 - 6,679,760 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
IZUMO1R
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1216,597,039 - 6,599,484 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl216,596,141 - 6,599,840 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha216,607,027 - 6,609,932 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0216,777,138 - 6,780,041 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl216,777,062 - 6,784,386 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1216,557,952 - 6,560,822 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0216,626,822 - 6,629,712 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0216,676,910 - 6,679,760 (-)NCBIUU_Cfam_GSD_1.0
IZUMO1R
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381194,304,580 - 94,308,146 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1194,304,580 - 94,308,146 (+)EnsemblGRCh38hg38GRCh38
GRCh371194,037,746 - 94,041,312 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361193,678,451 - 93,680,506 (+)NCBINCBI36Build 36hg18NCBI36
Celera1191,326,626 - 91,328,681 (+)NCBICelera
Cytogenetic Map11q21NCBI
HuRef1190,108,391 - 90,110,446 (+)NCBIHuRef
CHM1_11193,921,817 - 93,923,872 (+)NCBICHM1_1
T2T-CHM13v2.01194,311,597 - 94,315,165 (+)NCBIT2T-CHM13v2.0
Izumo1r
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39914,797,110 - 14,815,247 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl914,797,110 - 14,815,245 (-)EnsemblGRCm39 Ensembl
GRCm38914,885,814 - 14,903,951 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl914,885,814 - 14,903,949 (-)EnsemblGRCm38mm10GRCm38
MGSCv37914,690,258 - 14,708,395 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36914,636,207 - 14,654,325 (-)NCBIMGSCv36mm8
Celera912,166,552 - 12,184,689 (-)NCBICelera
Cytogenetic Map9A2NCBI
cM Map94.42NCBI
Izumo1r
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8820,025,830 - 20,030,829 (-)NCBIGRCr8
mRatBN7.2811,744,384 - 11,748,131 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl811,725,863 - 11,748,465 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx815,729,242 - 15,733,012 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0814,026,986 - 14,030,756 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0812,002,693 - 12,006,472 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0813,416,418 - 13,418,907 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl813,416,393 - 13,420,439 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0813,358,388 - 13,362,662 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4811,697,856 - 11,703,408 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera813,213,994 - 13,216,483 (-)NCBICelera
Cytogenetic Map8q12NCBI
Izumo1r
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955414283,630 - 287,433 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955414283,646 - 287,422 (-)NCBIChiLan1.0ChiLan1.0
IZUMO1R
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2995,158,740 - 95,162,308 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11196,250,459 - 96,254,027 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01189,318,370 - 89,322,004 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11192,805,614 - 92,807,669 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1192,805,614 - 92,807,669 (+)Ensemblpanpan1.1panPan2
Izumo1r
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494779,274,912 - 79,277,682 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936674595,106 - 616,513 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936674614,455 - 616,513 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IZUMO1R
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl926,517,292 - 26,520,860 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1926,516,091 - 26,520,949 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2930,211,999 - 30,215,363 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IZUMO1R
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1185,527,589 - 85,532,968 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl185,527,999 - 85,530,703 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604340,253,230 - 40,259,153 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Izumo1r
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473538,968,803 - 38,971,518 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473538,967,522 - 38,971,049 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in IZUMO1R
40 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 4 2 19 13 10 6 5 14 10 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000006695   ⟹   ENSCAFP00000006199
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl216,596,141 - 6,599,840 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845036118   ⟹   ENSCAFP00845028265
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl216,777,062 - 6,784,386 (-)Ensembl
RefSeq Acc Id: XM_038429635   ⟹   XP_038285563
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0216,777,138 - 6,780,041 (-)NCBI
RefSeq Acc Id: XM_038456426   ⟹   XP_038312354
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha216,607,027 - 6,609,932 (-)NCBI
RefSeq Acc Id: XM_038506096   ⟹   XP_038362024
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1216,557,952 - 6,560,822 (-)NCBI
RefSeq Acc Id: XM_038569333   ⟹   XP_038425261
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0216,676,910 - 6,679,760 (-)NCBI
RefSeq Acc Id: XM_038632311   ⟹   XP_038488239
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0216,626,822 - 6,629,712 (-)NCBI
Ensembl Acc Id: ENSCAFP00000006199   ⟸   ENSCAFT00000006695
RefSeq Acc Id: XP_038362024   ⟸   XM_038506096
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038488239   ⟸   XM_038632311
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038285563   ⟸   XM_038429635
- Peptide Label: isoform X1
- UniProtKB: A0A8I3P9X8 (UniProtKB/TrEMBL),   A0A8C0KTL0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038312354   ⟸   XM_038456426
- Peptide Label: isoform X1
- UniProtKB: A0A8P0PFU9 (UniProtKB/TrEMBL),   A0A8C0KTL0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038425261   ⟸   XM_038569333
- Peptide Label: isoform X3
Ensembl Acc Id: ENSCAFP00845028265   ⟸   ENSCAFT00845036118
Protein Domains
Folate receptor-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000004172 Ensembl
  ENSCAFG00000050969 UniProtKB/TrEMBL
  ENSCAFG00845020509 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000100168.1 UniProtKB/TrEMBL
  ENSCAFT00845036118 ENTREZGENE
  ENSCAFT00845036118.1 UniProtKB/TrEMBL
InterPro Folate_rcpt UniProtKB/TrEMBL
  Folate_rcpt-like UniProtKB/TrEMBL
NCBI Gene IZUMO1R ENTREZGENE
PANTHER PTHR10517 UniProtKB/TrEMBL
  SPERM-EGG FUSION PROTEIN JUNO UniProtKB/TrEMBL
Pfam Folate_rec UniProtKB/TrEMBL
UniProt A0A8C0KTL0 ENTREZGENE
  A0A8I3P9X8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PFU9 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:59053 ENTREZGENE