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Gene: TXNRD3 (thioredoxin reductase 3) Canis lupus familiaris

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Symbol:

TXNRD3

Name:

thioredoxin reductase 3

RGD ID:

12368907

Description:

ENCODES a protein that exhibits flavin adenine dinucleotide binding (inferred); oxidoreductase activity (inferred); oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor (inferred); INVOLVED IN blastocyst formation (ortholog); glutathione metabolic process (ortholog); ASSOCIATED WITH alkaptonuria (ortholog); cardiomyopathy (ortholog); colorectal adenoma (ortholog); FOUND IN cytosol (inferred); nucleoplasm (inferred)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TXNRD3 (thioredoxin reductase 3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Txnrd3 (thioredoxin reductase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Txnrd3 (thioredoxin reductase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Txnrd3 (thioredoxin reductase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TXNRD3 (thioredoxin reductase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Txnrd3 (thioredoxin reductase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TXNRD3 (thioredoxin reductase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TXNRD3 (thioredoxin reductase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	782,653 - 844,159 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	782,653 - 831,351 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	816,790 - 878,287 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	794,201 - 855,716 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	794,201 - 882,976 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	522,067 - 583,555 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	851,049 - 912,474 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	809,928 - 871,488 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TXNRD3	Dog	colorectal adenoma		ISO	TXNRD3 (Homo sapiens)	9068941	mRNA:increased expression:colorectum (human)	RGD	PMID:30469315 and REF_RGD_ID:151665806
TXNRD3	Dog	colorectal carcinoma		ISO	TXNRD3 (Homo sapiens)	9068941	mRNA:increased expression:colorectum (human)	RGD	PMID:30469315 and REF_RGD_ID:151665806

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TXNRD3	Dog	alkaptonuria		ISO	TXNRD3 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Alkaptonuria	ClinVar	PMID:12501223 more ...
TXNRD3	Dog	Primary Lymphedema with Myelodysplasia		ISO	TXNRD3 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:19449416 more ...

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TXNRD3	Dog	cardiomyopathy		ISO	TXNRD3 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:36421005

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TXNRD3	Dog	blastocyst formation	acts_upstream_of_or_within	ISO	Txnrd3 (Mus musculus)	9068941	PMID:27869233	MGI	PMID:27869233
TXNRD3	Dog	cell redox homeostasis	involved_in	IEA	InterPro:IPR046952	150520179		InterPro	GO_REF:0000002
TXNRD3	Dog	cell redox homeostasis	involved_in	IBA	CGD:CAL0000194377 more ...	150520179		GO_Central	GO_REF:0000033
TXNRD3	Dog	cellular oxidant detoxification	involved_in	IEA	GO:0004362 and GO:0004791	150520179		GOC	GO_REF:0000108
TXNRD3	Dog	cellular response to oxidative stress	involved_in	IBA	CGD:CAL0000194377 more ...	150520179		GO_Central	GO_REF:0000033
TXNRD3	Dog	glutathione metabolic process	involved_in	IBA	PANTHER:PTN002448883 more ...	150520179		GO_Central	GO_REF:0000033
TXNRD3	Dog	glutathione metabolic process	acts_upstream_of_or_within	ISO	Txnrd3 (Mus musculus)	9068941	PMID:11259642	MGI	PMID:11259642

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TXNRD3	Dog	cytosol	located_in	IEA	UniProtKB:H0YBQ0 more ...	150520179		Ensembl	GO_REF:0000107
TXNRD3	Dog	cytosol	is_active_in	IBA	PANTHER:PTN002448883 more ...	150520179		GO_Central	GO_REF:0000033
TXNRD3	Dog	mitochondrion	is_active_in	IBA	PANTHER:PTN000530560 more ...	150520179		GO_Central	GO_REF:0000033
TXNRD3	Dog	nucleoplasm	located_in	IEA	UniProtKB:H0YBQ0 more ...	150520179		Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TXNRD3	Dog	flavin adenine dinucleotide binding	enables	IEA	InterPro:IPR046952	150520179		InterPro	GO_REF:0000002
TXNRD3	Dog	flavin adenine dinucleotide binding	enables	IBA	PANTHER:PTN002448883 more ...	150520179		GO_Central	GO_REF:0000033
TXNRD3	Dog	glutathione-disulfide reductase (NADPH) activity	enables	IBA	CGD:CAL0000194377 more ...	150520179		GO_Central	GO_REF:0000033
TXNRD3	Dog	oxidoreductase activity	enables	IEA	UniProtKB-KW:KW-0560	150520179		UniProt	GO_REF:0000043
TXNRD3	Dog	oxidoreductase activity	enables	IEA	InterPro:IPR023753	150520179		InterPro	GO_REF:0000002
TXNRD3	Dog	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	enables	IEA	InterPro:IPR012999	150520179		InterPro	GO_REF:0000002
TXNRD3	Dog	protein binding	enables	ISO	PR:E9Q9D5	9068941	PMID:23055941	MGI	PMID:23055941
TXNRD3	Dog	thioredoxin-disulfide reductase (NADPH) activity	enables	IEA	InterPro:IPR006338	150520179		InterPro	GO_REF:0000002

PMID:22301074	PMID:30032202

TXNRD3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	782,653 - 844,159 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	782,653 - 831,351 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	816,790 - 878,287 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	794,201 - 855,716 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	794,201 - 882,976 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	522,067 - 583,555 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	851,049 - 912,474 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	809,928 - 871,488 (-)	NCBI		UU_Cfam_GSD_1.0

TXNRD3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	126,607,050 - 126,655,124 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	126,571,779 - 126,655,124 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	126,325,893 - 126,373,967 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	127,808,585 - 127,857,746 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	3	124,750,511 - 124,798,259 (-)	NCBI		Celera
Cytogenetic Map	3	q21.3	NCBI
HuRef	3	123,706,210 - 123,746,134 (-)	NCBI		HuRef
CHM1_1	3	126,288,907 - 126,336,657 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	129,339,825 - 129,387,575 (-)	NCBI		T2T-CHM13v2.0

Txnrd3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	89,620,970 - 89,652,511 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	89,620,970 - 89,652,511 (+)	Ensembl		GRCm39 Ensembl
GRCm38	6	89,643,988 - 89,675,529 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	89,643,988 - 89,675,529 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	89,593,982 - 89,625,523 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	89,609,639 - 89,641,155 (+)	NCBI		MGSCv36	mm8
Celera	6	91,567,454 - 91,599,003 (+)	NCBI		Celera
Cytogenetic Map	6	D1	NCBI
cM Map	6	40.01	NCBI

Txnrd3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	123,629,768 - 123,669,713 (+)	NCBI		GRCr8
mRatBN7.2	4	122,072,548 - 122,112,493 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	122,072,548 - 122,112,491 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	127,550,067 - 127,589,990 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	123,324,852 - 123,364,772 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	121,949,094 - 121,989,017 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	121,612,332 - 121,650,543 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	121,612,332 - 121,650,571 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	184,234,159 - 184,271,987 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	123,730,278 - 123,771,572 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	123,926,142 - 124,016,038 (+)	NCBI
Celera	4	111,023,437 - 111,062,376 (+)	NCBI		Celera
Cytogenetic Map	4	q34	NCBI

Txnrd3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955429	16,845,526 - 16,879,797 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955429	16,845,466 - 16,880,481 (+)	NCBI	ChiLan1.0	ChiLan1.0

TXNRD3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	124,531,653 - 124,579,914 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	124,536,126 - 124,584,724 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	123,644,679 - 123,697,563 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	130,966,614 - 131,013,117 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	130,967,026 - 131,013,667 (-)	Ensembl	panpan1.1		panPan2

Txnrd3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404942	21,159,839 - 21,189,862 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936798	1,203,418 - 1,230,988 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936798	1,190,975 - 1,231,732 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TXNRD3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	73,275,911 - 73,340,372 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	73,276,249 - 73,336,782 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	80,680,460 - 80,717,823 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TXNRD3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	54,359,169 - 54,417,126 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	54,361,034 - 54,417,397 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	111,873,995 - 111,932,686 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants in TXNRD3
438 total Variants

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10


RefSeq Transcripts	NM_001122778	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000231	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000058	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000291	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000006268 ⟹ ENSCAFP00000005807

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	20	782,653 - 831,351 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845022490 ⟹ ENSCAFP00845017660

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	20	794,201 - 882,976 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845022545 ⟹ ENSCAFP00845017697

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	20	794,201 - 882,976 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845022627 ⟹ ENSCAFP00845017751

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	20	794,201 - 882,976 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845022686 ⟹ ENSCAFP00845017792

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	20	794,201 - 882,976 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845022758 ⟹ ENSCAFP00845017845

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	20	794,201 - 847,139 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845022830 ⟹ ENSCAFP00845017895

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	20	794,201 - 847,139 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845022874 ⟹ ENSCAFP00845017933

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	20	794,201 - 847,139 (-)	Ensembl

RefSeq Acc Id:

NM_001122778 ⟹ NP_001116250

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	20	782,653 - 844,159 (-)	NCBI
Dog10K_Boxer_Tasha	20	816,790 - 878,287 (-)	NCBI
ROS_Cfam_1.0	20	794,201 - 855,716 (-)	NCBI
UMICH_Zoey_3.1	20	522,067 - 583,555 (-)	NCBI
UNSW_CanFamBas_1.0	20	851,049 - 912,474 (-)	NCBI
UU_Cfam_GSD_1.0	20	809,928 - 871,488 (-)	NCBI

Sequence:

show sequence

ATGAATTTCCCTGAAAACAGTGCCATGGCTCTGAAAGCTCCATCCAATGAAGCCTTGATGGATCAACTAGATGTTAAGGAACTGTTTTCTTCTCTGGGAGTTGCATGTAATATCTTGGAACTGGATCA
AGTTGATGATGGAGCCAATGTCCAGGAAGTACTGTCAGAAATCACTAATCAGAGAACTGTACCCAATATTTTTGTGAATAAAGTGCATATGGGTGGATGTGACCGAACTTTCCAGGCCCATCAGAGTG
GCTTATTACAGAAGCTCCTTCAGGAAGATTCAGCATACGATTATGATCTCATTGTCATTGGGGGCGGTTCTGGTGGCCTTGCATGTGCTCAGGAAGCTGCCATCTTGGGAAAGAAGGTTATGGTGCTA
GACTTTGTAGTCCCATCGCCTCAGGGCACATCCTGGGGTCTTGGCGGTACTTGTGTAAATGTGGGTTGTATTCCTAAGAAGTTGATGCATCAAGCTGCCCTTTTGGGGCAGGCACTGAGGGATGCCAG
GAAATTTGGCTGGGAGTACAGTCAACAAGTAAAGCACACCTGGGAGACTATGACAGAAGCGATTCAAAACCACATCGGCTCTCTAAACTGGGGCTACAGGCTGTCCCTGAGGGAGAAGGCTGTGGCCT
ATGTCAATTCCTATGGAGAATTTGTCGAACATCATAAAATAAAGGCAACCAATAGAAAAGGACAGGAAACTTGCTATACTGCTGCAAAATTTGTCCTAGCGACAGGCCAAAGGCCACGGTATTTAGGA
ATCCAAGGAGATAAAGAGTACTGTATTACTAGTGATGACCTTTTTTCTCTGCCTTATTGCCCTGGCAAAACGTTAGTGGTGGGTGCATCTTACGTTGCTCTGGAATGTGCAGGATTTCTCGCTGGCAT
TGGCTTAGATGTCACGATTATGGTGCGTTCGATCCTTCTTCGTGGGTTTGATCAAGAGATGGCAGAGAAAGTGGGTTCCTACATGGAACAACATGGTGTTAAGTTCTTAAGAAAATTTGTACCTGTCT
TGGTTCAGCAGTTGGAGAAAGGTTCACCTGGAAAGCTGAAAGTAGTGGCTAAATCCACTGAAGGACCAGAAACTATTGAAGAAATATATAATACAGTTTTGTTGGCAATTGGTCGTGACTCCTGTACA
AGGAAAATAGGTTTGGAGAAGATTGGTGTCAAAATCAATGAGAAGAGTGGCAAAATACCAGTAAATGATGTGGAACAGACCAATGTGCCTTATGTTTATGCTGTTGGGGATATTCTGGAGGGTAAACT
TGAGCTCACACCTGTTGCCATACAGGCAGGCAAGCTGCTGGCTCGAAGACTTTTTGCGGGCCGTTTAGAAAAGTGTGATTATGTAAATGTTCCAACTACAGTGTTTACTCCTTTGGAATATGGCTGCT
GTGGATTATCTGAAGAGAAAGCTATTGAAATGTATAAAAAAGAGAATCTCGAAGTGTATCATACTTTGTTCTGGCCTCTTGAATGGACAGTGGCCGGCAGAGACAACAATACTTGTTACGCAAAGATA
ATTTGCAATAAATTGGACAACTATCGGGTGATAGGATTCCATGTTCTCGGACCCAATGCCGGTGAGGTTACCCAGGGGTTTGCTGCCGCAATGAAATGTGGGCTCACAAAGCAGCTACTTGATGATAC
CATTGGAATTCATCCCACCTGTGGTGAGGTGTTTACGACTCTGGAGATCACAAAGTCGTCGGGACTAGACATCACTCAGAAGGGCTGCTGAGGCTAGCACTGCTGCTGTCTGGGTTTCCTTGTCATTT
CCTGCTCTCAGGGACAAGAGGGCCCCCGGGTAAAGTGAGTCGGTGCTCCTGCACCTGCTCTCCTGCATGGGGACCAGTGCTGGACTTTTGTCCCAGCACAGAGATGAGGAAGACGAGGAGACAGGACA
GCAGTGGGCATGTGCCCCGCGGGCTCGGCTGGCTGGAGAGGCAGGCAGGCTGCCTCCTTGACGCCTTAGCTCGGAACCGCTGTGAGGTGAGCTAAGGCCGATGTCCTCCATGCCAGGCCAGCTGCCCC
TGAAGGACCTTGCGGGCACGCAGTCAGCCAAGTTAACTATTCTGGTTGCTAGTGTTTTTATCCTCTTTCTTCATTGTTTCTCCAAAAGTGGCTGCTTAGTGATGAAAACTGGCCACACAGTGGGGCCC
TCCGGAGTGGGGGCCTGGGCTTGGTGTGTCCCCGAGGTGTGTCCCGGCAGTGCCTTTGGGAGCTGGCCGCGAAGCCCGGCGCACAGGTGGGAAAGCGGCCCGCAGGGCCCAGCTAGTCAGCAGGCCCG
CCTCGGGCCCCTCCCTCCCCTGATTCGCAGTGGCAACAGCCCCCAGGGCCTCTCTCTCTCTTTTAGTATCTCATGTCAGATACATGCTTGAATTCCTTCTCCGCGTTGATCTTCAGAGCAATA

hide sequence


Protein RefSeqs	NP_001116250	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000005807.5
	ENSCAFP00000068651.1
	ENSCAFP00000070772.1
	ENSCAFP00030015923.1
	ENSCAFP00030016074.1
	ENSCAFP00030016158.1
	ENSCAFP00040041980.1
	ENSCAFP00040041990.1
	ENSCAFP00040041997.1
	ENSCAFP00845017660.1
	ENSCAFP00845017697.1
	ENSCAFP00845017751.1
	ENSCAFP00845017792.1
	ENSCAFP00845017845
	ENSCAFP00845017845.1
	ENSCAFP00845017895.1
	ENSCAFP00845017933.1

RefSeq Acc Id:

NP_001116250 ⟸ NM_001122778

- UniProtKB:

A0A8C0N0Y9 (UniProtKB/TrEMBL), A0A8I3NHT0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MNFPENSAMALKAPSNEALMDQLDVKELFSSLGVACNILELDQVDDGANVQEVLSEITNQRTVPNIFVNKVHMGGCDRTFQAHQSGLLQKLLQEDSAYDYDLIVIGGGSGGLACAQEAAILGKKVMVL
DFVVPSPQGTSWGLGGTCVNVGCIPKKLMHQAALLGQALRDARKFGWEYSQQVKHTWETMTEAIQNHIGSLNWGYRLSLREKAVAYVNSYGEFVEHHKIKATNRKGQETCYTAAKFVLATGQRPRYLG
IQGDKEYCITSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTIMVRSILLRGFDQEMAEKVGSYMEQHGVKFLRKFVPVLVQQLEKGSPGKLKVVAKSTEGPETIEEIYNTVLLAIGRDSCT
RKIGLEKIGVKINEKSGKIPVNDVEQTNVPYVYAVGDILEGKLELTPVAIQAGKLLARRLFAGRLEKCDYVNVPTTVFTPLEYGCCGLSEEKAIEMYKKENLEVYHTLFWPLEWTVAGRDNNTCYAKI
ICNKLDNYRVIGFHVLGPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEITKSSGLDITQKGCUG

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Ensembl Acc Id:

ENSCAFP00000005807 ⟸ ENSCAFT00000006268

Ensembl Acc Id:

ENSCAFP00845017845 ⟸ ENSCAFT00845022758

Ensembl Acc Id:

ENSCAFP00845017895 ⟸ ENSCAFT00845022830

Ensembl Acc Id:

ENSCAFP00845017660 ⟸ ENSCAFT00845022490

Protein Domains

FAD/NAD(P)-binding Glutaredoxin Pyridine nucleotide-disulphide oxidoreductase

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000003884	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030009782	UniProtKB/TrEMBL
	ENSCAFG00040025742	UniProtKB/TrEMBL
	ENSCAFG00845012644	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000006268.5	UniProtKB/TrEMBL
	ENSCAFT00000094229.1	UniProtKB/TrEMBL
	ENSCAFT00000106057.1	UniProtKB/TrEMBL
	ENSCAFT00030018236.1	UniProtKB/TrEMBL
	ENSCAFT00030018412.1	UniProtKB/TrEMBL
	ENSCAFT00030018515.1	UniProtKB/TrEMBL
	ENSCAFT00040048076.1	UniProtKB/TrEMBL
	ENSCAFT00040048086.1	UniProtKB/TrEMBL
	ENSCAFT00040048093.1	UniProtKB/TrEMBL
	ENSCAFT00845022490.1	UniProtKB/TrEMBL
	ENSCAFT00845022545.1	UniProtKB/TrEMBL
	ENSCAFT00845022627.1	UniProtKB/TrEMBL
	ENSCAFT00845022686.1	UniProtKB/TrEMBL
	ENSCAFT00845022758	ENTREZGENE
	ENSCAFT00845022758.1	UniProtKB/TrEMBL
	ENSCAFT00845022830.1	UniProtKB/TrEMBL
	ENSCAFT00845022874.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.390.30	UniProtKB/TrEMBL
	3.50.50.60	UniProtKB/TrEMBL
	Glutaredoxin	UniProtKB/TrEMBL
InterPro	FAD/NAD-bd_sf	UniProtKB/TrEMBL
	FAD/NAD-binding_dom	UniProtKB/TrEMBL
	FAD/NAD-linked_Rdtase_dimer_sf	UniProtKB/TrEMBL
	Glutaredoxin	UniProtKB/TrEMBL
	Glutaredoxin_euk/vir	UniProtKB/TrEMBL
	GSHR/TRXR-like	UniProtKB/TrEMBL
	Pyr_nucl-diS_OxRdtase_dimer	UniProtKB/TrEMBL
	Pyr_OxRdtase_I_AS	UniProtKB/TrEMBL
	Thioredoxin-like_sf	UniProtKB/TrEMBL
	Thioredoxin/glutathione_Rdtase	UniProtKB/TrEMBL
NCBI Gene	TXNRD3	ENTREZGENE
PANTHER	GLUTATHIONE REDUCTASE	UniProtKB/TrEMBL
	THIOREDOXIN-DISULFIDE REDUCTASE	UniProtKB/TrEMBL
Pfam	Glutaredoxin	UniProtKB/TrEMBL
	Pyr_redox_2	UniProtKB/TrEMBL
	Pyr_redox_dim	UniProtKB/TrEMBL
PRINTS	FADPNR	UniProtKB/TrEMBL
	PNDRDTASEI	UniProtKB/TrEMBL
PROSITE	GLUTAREDOXIN_2	UniProtKB/TrEMBL
	PYRIDINE_REDOX_1	UniProtKB/TrEMBL
Superfamily-SCOP	SSF51905	UniProtKB/TrEMBL
	SSF52833	UniProtKB/TrEMBL
	SSF55424	UniProtKB/TrEMBL
UniProt	A0A8C0MXS5_CANLF	UniProtKB/TrEMBL
	A0A8C0N0Y9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0Z771_CANLF	UniProtKB/TrEMBL
	A0A8I3NDK7_CANLF	UniProtKB/TrEMBL
	A0A8I3NDW4_CANLF	UniProtKB/TrEMBL
	A0A8I3NHT0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3NPC6_CANLF	UniProtKB/TrEMBL
	A0A8I3NPF1_CANLF	UniProtKB/TrEMBL
	A0A8I3NYF6_CANLF	UniProtKB/TrEMBL
	A0A8I3RX66_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:48023	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD