Txnrd3 (thioredoxin reductase 3) - Rat Genome Database

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Gene: Txnrd3 (thioredoxin reductase 3) Rattus norvegicus
Analyze
Symbol: Txnrd3
Name: thioredoxin reductase 3
RGD ID: 1308363
Description: Predicted to enable thioredoxin-disulfide reductase (NADPH) activity. Predicted to be involved in cell redox homeostasis. Predicted to act upstream of or within blastocyst formation and glutathione metabolic process. Predicted to be located in nucleoplasm. Predicted to be active in cytosol and mitochondrion. Orthologous to human TXNRD3 (thioredoxin reductase 3); PARTICIPATES IN pyrimidine metabolic pathway; selenoamino acid metabolic pathway; INTERACTS WITH (+)-schisandrin B; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: LOC297437
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84123,629,768 - 123,669,713 (+)NCBIGRCr8
mRatBN7.24122,072,548 - 122,112,493 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4122,072,548 - 122,112,491 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4127,550,067 - 127,589,990 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04123,324,852 - 123,364,772 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04121,949,094 - 121,989,017 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04121,612,332 - 121,650,543 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4121,612,332 - 121,650,571 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04184,234,159 - 184,271,987 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44123,730,278 - 123,771,572 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14123,926,142 - 124,016,038 (+)NCBI
Celera4111,023,437 - 111,062,376 (+)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)
cytosol  (IBA,ISO)
mitochondrion  (IBA)
nucleoplasm  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Expression of Selenoprotein Genes and Association with Selenium Status in Colorectal Adenoma and Colorectal Cancer. Hughes DJ, etal., Nutrients. 2018 Nov 21;10(11). pii: nu10111812. doi: 10.3390/nu10111812.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:11259642   PMID:20018845   PMID:22479358   PMID:27645994   PMID:27869233   PMID:35076866  


Genomics

Comparative Map Data
Txnrd3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84123,629,768 - 123,669,713 (+)NCBIGRCr8
mRatBN7.24122,072,548 - 122,112,493 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4122,072,548 - 122,112,491 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4127,550,067 - 127,589,990 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04123,324,852 - 123,364,772 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04121,949,094 - 121,989,017 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04121,612,332 - 121,650,543 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4121,612,332 - 121,650,571 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04184,234,159 - 184,271,987 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44123,730,278 - 123,771,572 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14123,926,142 - 124,016,038 (+)NCBI
Celera4111,023,437 - 111,062,376 (+)NCBICelera
Cytogenetic Map4q34NCBI
TXNRD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383126,607,050 - 126,655,124 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3126,571,779 - 126,655,124 (-)EnsemblGRCh38hg38GRCh38
GRCh373126,325,893 - 126,373,967 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363127,808,585 - 127,857,746 (-)NCBINCBI36Build 36hg18NCBI36
Celera3124,750,511 - 124,798,259 (-)NCBICelera
Cytogenetic Map3q21.3NCBI
HuRef3123,706,210 - 123,746,134 (-)NCBIHuRef
CHM1_13126,288,907 - 126,336,657 (-)NCBICHM1_1
T2T-CHM13v2.03129,339,825 - 129,387,575 (-)NCBIT2T-CHM13v2.0
Txnrd3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39689,620,970 - 89,652,511 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl689,620,970 - 89,652,511 (+)EnsemblGRCm39 Ensembl
GRCm38689,643,988 - 89,675,529 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl689,643,988 - 89,675,529 (+)EnsemblGRCm38mm10GRCm38
MGSCv37689,593,982 - 89,625,523 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36689,609,639 - 89,641,155 (+)NCBIMGSCv36mm8
Celera691,567,454 - 91,599,003 (+)NCBICelera
Cytogenetic Map6D1NCBI
cM Map640.01NCBI
Txnrd3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542916,845,526 - 16,879,797 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542916,845,466 - 16,880,481 (+)NCBIChiLan1.0ChiLan1.0
TXNRD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22124,531,653 - 124,579,914 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13124,536,126 - 124,584,724 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03123,644,679 - 123,697,563 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13130,966,614 - 131,013,117 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3130,967,026 - 131,013,667 (-)Ensemblpanpan1.1panPan2
TXNRD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.120782,653 - 844,159 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl20782,653 - 831,351 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha20816,790 - 878,287 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.020794,201 - 855,716 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl20794,201 - 882,976 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.120522,067 - 583,555 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.020851,049 - 912,474 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.020809,928 - 871,488 (-)NCBIUU_Cfam_GSD_1.0
Txnrd3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494221,159,839 - 21,189,862 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367981,203,418 - 1,230,988 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367981,190,975 - 1,231,732 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TXNRD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1373,275,911 - 73,340,372 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11373,276,249 - 73,336,782 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21380,680,460 - 80,717,823 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TXNRD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12254,359,169 - 54,417,126 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2254,361,034 - 54,417,397 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041111,873,995 - 111,932,686 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Txnrd3
46 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)485253748148090731Rat
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)495174120140174120Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1578655Bmd11Bone mineral density QTL 1111femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)490850165135850165Rat
1300116Hrtrt5Heart rate QTL 53.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)4116179486151161268Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470362013132642728Rat
731165Uae21Urinary albumin excretion QTL 212.40.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)4106649412151649412Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4109866907167139601Rat
1549832Bss3Bone structure and strength QTL 311femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)4109827074154827074Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482798864152731274Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)486730991131730991Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)481192555126192555Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)450119848146803430Rat
1578670Bss14Bone structure and strength QTL 1416.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)487327165132327165Rat
70201Gcr1Gastric cancer resistance QTL 12.7stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)4120260281147278687Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)456647873149491524Rat
1331759Hrtrt13Heart rate QTL 133.54628heart pumping trait (VT:2000009)heart rate (CMO:0000002)4110275411168266883Rat
724535Cm18Cardiac mass QTL 182.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)4118856416163856416Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
1578662Bss15Bone structure and strength QTL 1519.6femur width (VT:1000666)femoral neck width (CMO:0001695)487327165132327165Rat
2302049Pia32Pristane induced arthritis QTL 325.10.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)4105789505150789505Rat
6478763Anxrr46Anxiety related response QTL 460.07428locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4110870972155870972Rat
6478760Anxrr45Anxiety related response QTL 450.06717locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4110870972155870972Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4119428175157578333Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)459948935154902892Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat
738015Pia9Pristane induced arthritis QTL 94.50.048joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)480694870125694870Rat
7207480Bss105Bone structure and strength QTL 1058.1femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)4109827074154827074Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)493308457167139447Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)473169846132642728Rat
634334Xhs3X-ray hypersensitivity QTL 310intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)484728680129854654Rat
61406Scwia1Streptococcal cell wall induced arthritis QTL 12.3joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)4106805662151805662Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)478878504123878504Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)462277855128289560Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)485379421167139601Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)456698790126192555Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
2293840Kiddil9Kidney dilation QTL 92.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)4120926564148090731Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4114627026159627026Rat
12798523Anxrr56Anxiety related response QTL 562.830.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)485253748150276390Rat
61434Cia3Collagen induced arthritis QTL 34.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4103194656148194656Rat
12798527Anxrr58Anxiety related response QTL 584.110.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4119463257147278687Rat

Markers in Region
RH138372  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24122,112,235 - 122,112,372 (+)MAPPERmRatBN7.2
Rnor_6.04121,650,286 - 121,650,422NCBIRnor6.0
Rnor_5.04184,271,730 - 184,271,866UniSTSRnor5.0
RGSC_v3.44123,771,315 - 123,771,451UniSTSRGSC3.4
Celera4111,062,119 - 111,062,255UniSTS
RH 3.4 Map4731.92UniSTS
Cytogenetic Map4q34UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 4 16 8 22 2
Low 3 41 53 41 19 41 8 11 58 27 19 9 8
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000077374   ⟹   ENSRNOP00000071434
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4122,072,689 - 122,112,478 (+)Ensembl
Rnor_6.0 Ensembl4121,612,332 - 121,650,541 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000084494   ⟹   ENSRNOP00000074078
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4122,072,548 - 122,112,491 (+)Ensembl
Rnor_6.0 Ensembl4121,612,348 - 121,650,571 (+)Ensembl
RefSeq Acc Id: NM_001106609   ⟹   NP_001100079
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84123,629,768 - 123,669,713 (+)NCBI
mRatBN7.24122,072,548 - 122,112,493 (+)NCBI
Rnor_6.04121,612,332 - 121,650,543 (+)NCBI
Rnor_5.04184,234,159 - 184,271,987 (+)NCBI
RGSC_v3.44123,730,278 - 123,771,572 (+)RGD
Celera4111,023,437 - 111,062,376 (+)RGD
Sequence:
RefSeq Acc Id: NM_001184712   ⟹   NP_001171641
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84123,629,768 - 123,669,713 (+)NCBI
mRatBN7.24122,072,548 - 122,112,493 (+)NCBI
Rnor_6.04121,612,332 - 121,650,543 (+)NCBI
Rnor_5.04184,234,159 - 184,271,987 (+)NCBI
Celera4111,023,437 - 111,062,376 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001100079 (Get FASTA)   NCBI Sequence Viewer  
  NP_001171641 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL91334 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000071434.2
  ENSRNOP00000074078.2
RefSeq Acc Id: NP_001100079   ⟸   NM_001106609
- Peptide Label: isoform 2
- UniProtKB: A0A0G2K0G3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001171641   ⟸   NM_001184712
- Peptide Label: isoform 1
- UniProtKB: A0A0G2K764 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000074078   ⟸   ENSRNOT00000084494
RefSeq Acc Id: ENSRNOP00000071434   ⟸   ENSRNOT00000077374
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K0G3-F1-model_v2 AlphaFold A0A0G2K0G3 1-651 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693242
Promoter ID:EPDNEW_R3765
Type:initiation region
Name:Txnrd3_1
Description:thioredoxin reductase 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04121,612,342 - 121,612,402EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308363 AgrOrtholog
BioCyc Gene G2FUF-43766 BioCyc
BioCyc Pathway THIOREDOX-PWY [thioredoxin pathway] BioCyc
BioCyc Pathway Image THIOREDOX-PWY BioCyc
Ensembl Genes ENSRNOG00000059810 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000077374.2 UniProtKB/TrEMBL
  ENSRNOT00000084494.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.390.30 UniProtKB/TrEMBL
  3.50.50.60 UniProtKB/TrEMBL
  Glutaredoxin UniProtKB/TrEMBL
InterPro FAD/NAD-bd_sf UniProtKB/TrEMBL
  FAD/NAD-linked_Rdtase_dimer UniProtKB/TrEMBL
  Glutaredoxin UniProtKB/TrEMBL
  Glutaredoxin_euk/vir UniProtKB/TrEMBL
  GSHR/TRXR-like UniProtKB/TrEMBL
  Pyr_nuc-diS_OxRdtase UniProtKB/TrEMBL
  Pyr_nucl-diS_OxRdtase_dimer UniProtKB/TrEMBL
  Pyr_nucl-diS_OxRdtase_FAD/NAD UniProtKB/TrEMBL
  Pyr_OxRdtase_I_AS UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/TrEMBL
  Thioredoxin/glutathione_Rdtase UniProtKB/TrEMBL
NCBI Gene 297437 ENTREZGENE
PANTHER GLUTATHIONE REDUCTASE UniProtKB/TrEMBL
  THIOREDOXIN REDUCTASE 3 UniProtKB/TrEMBL
Pfam Glutaredoxin UniProtKB/TrEMBL
  Pyr_redox_2 UniProtKB/TrEMBL
  Pyr_redox_dim UniProtKB/TrEMBL
PhenoGen Txnrd3 PhenoGen
PIRSF Mercury_reductase_MerA UniProtKB/TrEMBL
PRINTS FADPNR UniProtKB/TrEMBL
  PNDRDTASEI UniProtKB/TrEMBL
PROSITE GLUTAREDOXIN_2 UniProtKB/TrEMBL
  PYRIDINE_REDOX_1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000059810 RatGTEx
Superfamily-SCOP SSF51905 UniProtKB/TrEMBL
  SSF52833 UniProtKB/TrEMBL
  SSF55424 UniProtKB/TrEMBL
UniProt A0A0G2K0G3 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2K764 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Txnrd3  thioredoxin reductase 3   Txnrd3_predicted  thioredoxin reductase 3 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Txnrd3_predicted  thioredoxin reductase 3 (predicted)      Symbol and Name status set to approved 70820 APPROVED