FARSA (phenylalanyl-tRNA synthetase subunit alpha) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: FARSA (phenylalanyl-tRNA synthetase subunit alpha) Canis lupus familiaris
Analyze
Symbol: FARSA
Name: phenylalanyl-tRNA synthetase subunit alpha
RGD ID: 12346687
Description: ENCODES a protein that exhibits aminoacyl-tRNA ligase activity (inferred); ATP binding (inferred); metal ion binding (inferred); INVOLVED IN phenylalanyl-tRNA aminoacylation (inferred); protein heterotetramerization (inferred); translation (inferred); PARTICIPATES IN phenylketonuria pathway; tyrosinemia type II pathway; tyrosinemia type III pathway; ASSOCIATED WITH Aicardi-Goutieres Syndrome 4 (ortholog); alpha-mannosidosis (ortholog); Charcot-Marie-Tooth disease dominant intermediate B (ortholog); FOUND IN cytoplasm (inferred); phenylalanine-tRNA ligase complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: phenylalanine--tRNA ligase alpha subunit; phenylalanyl-tRNA synthetase alpha subunit
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12049,258,827 - 49,267,279 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2049,258,845 - 49,267,198 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2049,131,070 - 49,139,532 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02049,775,682 - 49,784,201 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2049,775,704 - 49,819,242 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12048,986,876 - 48,995,337 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02049,413,365 - 49,421,812 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02049,655,888 - 49,664,348 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FARSA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12049,258,827 - 49,267,279 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2049,258,845 - 49,267,198 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2049,131,070 - 49,139,532 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02049,775,682 - 49,784,201 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2049,775,704 - 49,819,242 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12048,986,876 - 48,995,337 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02049,413,365 - 49,421,812 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02049,655,888 - 49,664,348 (+)NCBIUU_Cfam_GSD_1.0
FARSA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381912,922,479 - 12,933,711 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1912,922,479 - 12,934,037 (-)EnsemblGRCh38hg38GRCh38
GRCh371913,033,293 - 13,044,525 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361912,894,284 - 12,905,558 (-)NCBINCBI36Build 36hg18NCBI36
Build 341912,894,292 - 12,905,522NCBI
Celera1912,923,020 - 12,934,291 (-)NCBICelera
Cytogenetic Map19p13.13NCBI
HuRef1912,605,186 - 12,616,461 (-)NCBIHuRef
CHM1_11913,033,781 - 13,045,058 (-)NCBICHM1_1
T2T-CHM13v2.01913,046,966 - 13,058,199 (-)NCBIT2T-CHM13v2.0
Farsa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39885,583,597 - 85,595,886 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl885,583,618 - 85,595,886 (+)EnsemblGRCm39 Ensembl
GRCm38884,856,969 - 84,869,257 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl884,856,989 - 84,869,257 (+)EnsemblGRCm38mm10GRCm38
MGSCv37887,380,885 - 87,393,156 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36887,747,129 - 87,757,131 (+)NCBIMGSCv36mm8
Celera889,156,659 - 89,168,787 (+)NCBICelera
Cytogenetic Map8C3NCBI
cM Map841.23NCBI
Farsa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81940,196,255 - 40,205,830 (-)NCBIGRCr8
mRatBN7.21923,291,409 - 23,300,985 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1923,268,869 - 23,300,980 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1930,114,305 - 30,123,855 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01930,768,669 - 30,778,219 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01932,991,355 - 33,000,904 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01925,969,255 - 25,978,777 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1925,969,255 - 25,978,776 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01936,944,878 - 36,954,400 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41924,947,663 - 24,957,186 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11924,952,488 - 24,962,012 (-)NCBI
Celera1922,848,305 - 22,857,809 (-)NCBICelera
Cytogenetic Map19q11NCBI
Farsa
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541531,968,980 - 31,981,424 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541531,972,888 - 31,981,424 (-)NCBIChiLan1.0ChiLan1.0
FARSA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22017,851,642 - 17,863,414 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11916,852,290 - 16,864,068 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01912,484,607 - 12,496,160 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11913,227,193 - 13,238,085 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1913,227,193 - 13,238,244 (-)Ensemblpanpan1.1panPan2
Farsa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118208,364,421 - 208,372,363 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366591,981,723 - 1,990,322 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366591,982,343 - 1,990,277 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FARSA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl266,105,429 - 66,118,191 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1266,105,393 - 66,114,867 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2266,271,545 - 66,280,456 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FARSA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1611,602,352 - 11,613,851 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl611,600,516 - 11,613,345 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660748,173,868 - 8,185,230 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Farsa
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624901492,817 - 505,911 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624901492,673 - 505,815 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in FARSA
63 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000027079   ⟹   ENSCAFP00000025179
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2049,258,845 - 49,267,198 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000063630   ⟹   ENSCAFP00000065603
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2049,258,845 - 49,266,554 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000066818   ⟹   ENSCAFP00000065409
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2049,258,845 - 49,267,198 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845027282   ⟹   ENSCAFP00845021469
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2049,775,704 - 49,784,201 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845027330   ⟹   ENSCAFP00845021512
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2049,775,713 - 49,819,242 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845027407   ⟹   ENSCAFP00845021570
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2049,775,713 - 49,819,242 (+)Ensembl
RefSeq Acc Id: XM_038428451   ⟹   XP_038284379
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02049,775,682 - 49,784,201 (+)NCBI
RefSeq Acc Id: XM_038504095   ⟹   XP_038360023
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12048,986,876 - 48,995,337 (+)NCBI
RefSeq Acc Id: XM_038567124   ⟹   XP_038423052
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02049,655,888 - 49,664,348 (+)NCBI
RefSeq Acc Id: XM_038631267   ⟹   XP_038487195
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02049,413,365 - 49,421,812 (+)NCBI
RefSeq Acc Id: XM_533900   ⟹   XP_533900
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12049,258,827 - 49,267,279 (+)NCBI
Dog10K_Boxer_Tasha2049,131,070 - 49,139,532 (+)NCBI
Sequence:
RefSeq Acc Id: XP_533900   ⟸   XM_533900
- UniProtKB: A0A8C0P139 (UniProtKB/TrEMBL),   A0A8C0QVU1 (UniProtKB/TrEMBL),   A0A8I3NX27 (UniProtKB/TrEMBL),   A0A8C0TLJ6 (UniProtKB/TrEMBL),   A0A8I3NTN9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000065603   ⟸   ENSCAFT00000063630
Ensembl Acc Id: ENSCAFP00000065409   ⟸   ENSCAFT00000066818
Ensembl Acc Id: ENSCAFP00000025179   ⟸   ENSCAFT00000027079
RefSeq Acc Id: XP_038360023   ⟸   XM_038504095
RefSeq Acc Id: XP_038487195   ⟸   XM_038631267
RefSeq Acc Id: XP_038284379   ⟸   XM_038428451
- UniProtKB: A0A8C0P139 (UniProtKB/TrEMBL),   A0A8C0QVU1 (UniProtKB/TrEMBL),   A0A8I3NX27 (UniProtKB/TrEMBL),   A0A8C0TLJ6 (UniProtKB/TrEMBL),   A0A8I3NTN9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038423052   ⟸   XM_038567124
- UniProtKB: A0A8C0P139 (UniProtKB/TrEMBL),   A0A8C0QVU1 (UniProtKB/TrEMBL),   A0A8C0TLJ6 (UniProtKB/TrEMBL),   A0A8I3NTN9 (UniProtKB/TrEMBL),   A0A8I3NX27 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845021512   ⟸   ENSCAFT00845027330
Ensembl Acc Id: ENSCAFP00845021570   ⟸   ENSCAFT00845027407
Ensembl Acc Id: ENSCAFP00845021469   ⟸   ENSCAFT00845027282
Promoters
RGD ID:13687003
Promoter ID:EPDNEW_C5071
Type:multiple initiation site
Name:FARSA_1
Description:phenylalanyl-tRNA synthetase alpha subunit
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12049,258,845 - 49,258,905EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000017096 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030018735 UniProtKB/TrEMBL
  ENSCAFG00040023619 UniProtKB/TrEMBL
  ENSCAFG00845015291 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000027079.5 UniProtKB/TrEMBL
  ENSCAFT00000063630.2 UniProtKB/TrEMBL
  ENSCAFT00000066818.2 UniProtKB/TrEMBL
  ENSCAFT00030034501.1 UniProtKB/TrEMBL
  ENSCAFT00030034565.1 UniProtKB/TrEMBL
  ENSCAFT00040043978.1 UniProtKB/TrEMBL
  ENSCAFT00040044004.1 UniProtKB/TrEMBL
  ENSCAFT00040044020.1 UniProtKB/TrEMBL
  ENSCAFT00040044059.1 UniProtKB/TrEMBL
  ENSCAFT00845027282.1 UniProtKB/TrEMBL
  ENSCAFT00845027330 ENTREZGENE
  ENSCAFT00845027330.1 UniProtKB/TrEMBL
  ENSCAFT00845027407.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.2320 UniProtKB/TrEMBL
  1.10.10.2330 UniProtKB/TrEMBL
  3.30.1370.240 UniProtKB/TrEMBL
InterPro aa-tRNA-synth_II UniProtKB/TrEMBL
  aa-tRNA-synth_II/BPL/LPL UniProtKB/TrEMBL
  Phe-tRNA-synth_IIc_asu UniProtKB/TrEMBL
  Phenylalanyl-tRNA_Synthase UniProtKB/TrEMBL
  PheRS_DBD1 UniProtKB/TrEMBL
  PheRS_DBD2 UniProtKB/TrEMBL
  PheRS_DBD3 UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report cfa:476695 UniProtKB/TrEMBL
NCBI Gene FARSA ENTREZGENE
PANTHER PHENYLALANINE--TRNA LIGASE ALPHA SUBUNIT UniProtKB/TrEMBL
  PHENYLALANYL-TRNA SYNTHETASE UniProtKB/TrEMBL
Pfam PheRS_DBD1 UniProtKB/TrEMBL
  PheRS_DBD2 UniProtKB/TrEMBL
  PheRS_DBD3 UniProtKB/TrEMBL
  tRNA-synt_2d UniProtKB/TrEMBL
PROSITE AA_TRNA_LIGASE_II UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
  SSF55681 UniProtKB/TrEMBL
UniProt A0A8C0P139 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0QVU1 ENTREZGENE
  A0A8C0TK37_CANLF UniProtKB/TrEMBL
  A0A8C0TLJ6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0TR06_CANLF UniProtKB/TrEMBL
  A0A8I3NTN9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NX27 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3S1E0_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:40733 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-01 FARSA  phenylalanyl-tRNA synthetase subunit alpha    phenylalanyl-tRNA synthetase alpha subunit  Symbol and/or name change 5135510 APPROVED