VPS37A (VPS37A subunit of ESCRT-I)

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Gene: VPS37A (VPS37A subunit of ESCRT-I) Canis lupus familiaris

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Symbol:

VPS37A

Name:

VPS37A subunit of ESCRT-I

RGD ID:

12297573

Description:

INVOLVED IN catabolic process (inferred); protein transport (inferred); ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (inferred); ASSOCIATED WITH hereditary spastic paraplegia (ortholog); hereditary spastic paraplegia 53 (ortholog); transverse myelitis (ortholog); FOUND IN centrosome (inferred); cytosol (inferred); endosome (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

vacuolar protein sorting-associated protein 37A; VPS37A, ESCRT-I subunit

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	VPS37A (VPS37A subunit of ESCRT-I)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Vps37a (vacuolar protein sorting 37A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Vps37a (VPS37A subunit of ESCRT-I)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Vps37a (VPS37A subunit of ESCRT-I)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	VPS37A (VPS37A subunit of ESCRT-I)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Vps37a (VPS37A subunit of ESCRT-I)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	VPS37A (VPS37A subunit of ESCRT-I)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	VPS37A (VPS37A subunit of ESCRT-I)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Vps37a (VPS37A subunit of ESCRT-I)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	40,571,892 - 40,624,359 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	40,571,892 - 40,620,885 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	41,069,350 - 41,120,875 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	42,625,545 - 42,677,128 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	42,625,538 - 42,682,796 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	40,718,884 - 40,770,708 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	41,262,142 - 41,313,723 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	41,455,590 - 41,507,257 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

hereditary spastic paraplegia (ISO)

hereditary spastic paraplegia 53 (ISO)

transverse myelitis (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

catabolic process (IEA)

protein transport (IEA)

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (IEA)

Cellular Component

centrosome (IEA)

cytosol (IEA)

endosome (IEA)

ESCRT I complex (IEA)

intracellular membrane-bounded organelle (IEA)

late endosome membrane (IEA)

nucleoplasm (IEA)

Molecular Function

protein binding (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

VPS37A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	40,571,892 - 40,624,359 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	40,571,892 - 40,620,885 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	41,069,350 - 41,120,875 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	42,625,545 - 42,677,128 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	42,625,538 - 42,682,796 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	40,718,884 - 40,770,708 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	41,262,142 - 41,313,723 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	41,455,590 - 41,507,257 (+)	NCBI		UU_Cfam_GSD_1.0

VPS37A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	17,246,958 - 17,333,455 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	17,246,931 - 17,302,427 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	17,104,467 - 17,190,964 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	17,148,851 - 17,197,418 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	8	16,070,442 - 16,121,576 (+)	NCBI		Celera
Cytogenetic Map	8	p22	NCBI
HuRef	8	15,649,267 - 15,700,401 (+)	NCBI		HuRef
CHM1_1	8	17,305,854 - 17,356,966 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	17,514,555 - 17,601,063 (+)	NCBI		T2T-CHM13v2.0

Vps37a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	40,964,482 - 41,004,175 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	40,964,824 - 41,003,798 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	40,511,742 - 40,551,134 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	40,511,783 - 40,550,757 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	41,597,137 - 41,636,488 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	42,010,644 - 42,048,569 (+)	NCBI		MGSCv36	mm8
Celera	8	43,161,646 - 43,200,586 (+)	NCBI		Celera
Cytogenetic Map	8	A4	NCBI
cM Map	8	23.89	NCBI

Vps37a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	58,434,802 - 58,478,777 (-)	NCBI		GRCr8
mRatBN7.2	16	51,736,170 - 51,775,384 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	51,737,481 - 51,775,390 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	57,067,451 - 57,105,724 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	60,455,877 - 60,494,359 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	55,701,405 - 55,739,678 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	54,860,811 - 54,899,410 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	54,860,868 - 54,899,347 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	54,562,360 - 54,602,139 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	55,077,793 - 55,118,155 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	16	49,629,073 - 49,667,046 (-)	NCBI		Celera
Cytogenetic Map	16	q12.1	NCBI

Vps37a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955463	257,934 - 285,228 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955463	254,407 - 285,178 (-)	NCBI	ChiLan1.0	ChiLan1.0

VPS37A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	35,706,607 - 35,755,222 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	11,441,136 - 11,489,749 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	16,459,660 - 16,508,333 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	13,404,889 - 13,455,914 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	13,404,889 - 13,456,046 (+)	Ensembl	panpan1.1		panPan2

Vps37a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	38,798,354 - 38,836,225 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936573	6,306,536 - 6,340,271 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936573	6,306,218 - 6,343,544 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

VPS37A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	4,949,644 - 4,988,074 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	4,949,632 - 5,014,842 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	5,343,722 - 5,356,880 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

VPS37A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	15,333,570 - 15,384,451 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	15,333,557 - 15,374,678 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666052	26,892,933 - 26,945,463 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Vps37a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624769	22,021,638 - 22,046,794 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624769	22,022,808 - 22,047,068 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in VPS37A
456 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_038452685	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038452686	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038497773	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038497774	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038497775	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038560245	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038560246	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038560247	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038624294	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038624295	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038624296	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038690045	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038690046	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038690047	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_532826	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000184	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000104	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000038933 ⟹ ENSCAFP00000034722

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	16	40,571,892 - 40,620,885 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000070387 ⟹ ENSCAFP00000047788

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	16	40,572,211 - 40,620,885 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845026207 ⟹ ENSCAFP00845020662

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	16	42,625,538 - 42,682,796 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845026221 ⟹ ENSCAFP00845020671

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	16	42,625,873 - 42,682,796 (+)	Ensembl

RefSeq Acc Id:

XM_038452685 ⟹ XP_038308613

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	16	41,069,676 - 41,120,875 (+)	NCBI

RefSeq Acc Id:

XM_038452686 ⟹ XP_038308614

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	16	41,085,757 - 41,120,875 (+)	NCBI

RefSeq Acc Id:

XM_038497773 ⟹ XP_038353701

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	16	40,718,884 - 40,770,708 (+)	NCBI

RefSeq Acc Id:

XM_038497774 ⟹ XP_038353702

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	16	40,719,210 - 40,770,708 (+)	NCBI

RefSeq Acc Id:

XM_038497775 ⟹ XP_038353703

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	16	40,735,514 - 40,770,708 (+)	NCBI

RefSeq Acc Id:

XM_038560245 ⟹ XP_038416173

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	16	41,455,590 - 41,507,257 (+)	NCBI

RefSeq Acc Id:

XM_038560246 ⟹ XP_038416174

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	16	41,455,916 - 41,507,257 (+)	NCBI

RefSeq Acc Id:

XM_038560247 ⟹ XP_038416175

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	16	41,472,058 - 41,507,257 (+)	NCBI

RefSeq Acc Id:

XM_038624294 ⟹ XP_038480222

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	16	41,262,142 - 41,313,723 (+)	NCBI

RefSeq Acc Id:

XM_038624295 ⟹ XP_038480223

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	16	41,262,468 - 41,313,723 (+)	NCBI

RefSeq Acc Id:

XM_038624296 ⟹ XP_038480224

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	16	41,278,590 - 41,313,723 (+)	NCBI

RefSeq Acc Id:

XM_038690045 ⟹ XP_038545973

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	16	42,625,545 - 42,677,128 (+)	NCBI

RefSeq Acc Id:

XM_038690046 ⟹ XP_038545974

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	16	42,625,871 - 42,677,128 (+)	NCBI

RefSeq Acc Id:

XM_038690047 ⟹ XP_038545975

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	16	42,641,997 - 42,677,128 (+)	NCBI

RefSeq Acc Id:

XM_532826 ⟹ XP_532826

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	16	40,571,892 - 40,624,359 (+)	NCBI
Dog10K_Boxer_Tasha	16	41,069,350 - 41,120,875 (+)	NCBI

Sequence:

show sequence

GCGGGGGTGGCGGGGCGCGGGCGGTCTAGCCGCCGCTCGGGCTGGTTTGCGCGCTGAGGCCGGA
AAGTAAGAGCTGCGTGTGCCGCCCGGATGCATTCCTCGCTCTAGCTGCCGGCAAGCAGGGTGTT
GACGCCCGTCGCCCAGCCGCCGGTGATCCCCCCGGCCGGGCTTCCTTGGAGGAGACGCGGCCCC
CCCGGCACTTGGGACCCGGGCGTCTCGGACCGCTCGTCCTGTCGCTGGGGAACCGCGCGCGGGC
CGGAGCAGCTGGCAGAAGCAGGCCGGAGCCTTCCGGGGCCTCGGGCGCGGGGACCCGTGGAGGA
TGAGCTGGCTCTTCCCGCTGACCAAGAGCGCCTCCTCCTCCGCAGCTGGGTCCCCCGCTGGCCT
CACCAGCCTCCAGCAGCAGAAGCAGCGCCTCATAGAGTCCCTCCGGAATTCACACTCCAGTATA
GCTGAAATACAGAAAGATGTGGAATACAGATTGCCATTCACCGTAAACAACCTGACAATTAACA
TTAATATATTACTCCCTCCACAGTTTCCTCAGGAAAAACCAGTGATCAGTGTTTACCCACCAAT
ACAACATCACTTAATGGATAAACAAGGAGTATATGTTACCTCTCCATTAGTAAACAATTTTACA
ATGCACTCAGATCTTGGAAAAATTATTCAGAGTCTGTTGGATGAGTTTTGGAAGAATCCTCCAG
TTTTAGCTCCTTCTTCAACAGCATTTCCATACCTGTACAGTAATCCAAGTGGGCTGCCTCCTTA
TGCATCTCAGGGTTTCCCATTTCTTTCTCCATTTCCCCCACAAGAACCTAACAGGACTGTCACT
TCTTTGTCTGTTGCTGACACTATTTCTTCTTCAACAACAAGTTACACACCAGCCAAACCTGCAG
CTCCTTTTGGCATCCTTTCAAATCTGCCGCTACCTGTTCCTACAACAGACACATCAGCACCGAT
AAGCCAAAATGGTTTTGGTTACAAGATGCCAGATGTTCCTGATACATTTCCAGAACTCTCAGAA
CTAAGTGTGTCACAGCTTACAGATATGAATGAACAAGAGGAAATATTACTAGAACAGTTTCTGA
CTTTGCCCCAACTAAAACAGATTATTACTGACAAGGATGACTTAGTAAAAAGTATTGAAGAGCT
AGCAAGAAAAAATCTCCTTTTGGAGCCCAGCTTGGAAGCCAAAAGGCAAACTGTTTTAGATAAG
TATGAATTGCTTACACAACTGAAATCTGCTTTTGAAAAGAAGATGCAAAGGCAGCATGAACTTA
GTGAGAGTTGTAGTGTGAGTGCCCTACAGGCAAGACTGAAAGTAGCTGCACATGAAGCTGAGGA
AGAATCTGATAATATTGCTGAAGATTTCTTAGAGGGAAAAACTGAAATAGATGATTTTCTCAGT
AGCTTCATGGAAAAGAGAACAATCTGCCACTGTAGAAGAGCCAAGGAAGAGAAACTTCAACAAG
CAATAACAGTGCATAGCCAATTCCATGCCCCACTATAGATTTTCCTGAAAACATAAACCACCAA
GACAGAAATGACACAAGACTAAGCACATTTATATGTATGATTTGCAAATTGGCATTTCATCACA
ATGGCTGAATTCATAAATATTCTGGATAGACTATATGCAGAACTGAGACTGATTTTGTACAGAT
TATAGAATAACTGCTGTGGTCTTTGCTTTGAGAAATTTTTCTGCATGATTTGCACTATAAATGT
TTATTTATTGTTGATAAATCCTATCATATTTAAGTTCCACTGCTGTTCCTCTTTTATTAAGTAC
CTATGCATGTAATTTTAGCTAGTATCAATATTTTATAAAGTTGCTTCATTTAAATTTATATTTT
TAGTTTGAAACTGCCTCATTTCTTTATCAAAAATGGTTTGTTTAGATATTTTTCCTCTTAACCT
TTTTGAAAAATGACTATTTTCAACTATAGAAAGCCTTATTTTTCCTTCTATCATGATGATAAAA
CTTTAAAAAACATTTGTTTTTAAATTATTCATAGTGTCAGGAAATATCAAACCTACTAATGTGC
CATCTGAAAAAAGTAACTTTTAATACACAATAAATCAAGAGAATACATCAGCTGCCCATTTATT
GTTTAATTTTTAAAATTAAAGATACATTTAAGAAGCAATACAGTTAAATAATTATTTTACCTAG
CAGAAAAAAAATTGCCTTCCACTTCACCCAGTCCAACATAAACTTTCATACTAATTTTTTTATA
TAAATATGATAGATTTATGATTGGATAATGAAATACTTTATAAATTCCTAGTGTTAAAAACAAT
CTTTTTGTTAATAAATAGAAAATCTAGACACAGAAGTCAATGAATTTTTTTGACCTTTACTGTG
AGTTAGCTTTTCATAAGAGAACAGCTTTAGTAATAATATTTAACTTTTAGGCAGTCCAGTTTTT
AATTAGTTTTATTAAATTTGCTCTTTAAATGATACAGTGTTCAGTAGTTTGCTTCTGTACCATG
TTTCAGAATGAACACATTTTATGGGTAGCTGTAAAAGCTAATAAAGGAGAAAATCTGTAACTAT
ATGTATCTGAGGCTTGGTAAGTTAGTATCTAAATCACAAAACAATTTAGTGCAAATTTTTGTTT
AAATTTCATCTCAATATATATTGTTATTTCCAAATGCCAGCATATAGTAGTACAGATTTCTTTT
TCCTTCATTCTGTTTCTTTCTATACACATTCTTGGCAATAGAACTTTAGGAAAAACAAAATTAT
TTTCCTAGACTTGAAAAATATTTAATCTGTCTTTGCTTTGTGGAAGAGCAAGTATTCATATGGA
CTATAAATATATAATTGGAATAAAGATGTTAACTTTCACTAATTGCCTGTCTCACTAGCGCTGT
GCTAAGGGCATGCTGTTTAATCTTCAAAATGACCAGACATGATTTTTATGGATTTGTAGATGAA
ATAACTGAGGTAAGTGTTTTAAATTTGTGGCAGAGTCTTCTGGGTATTTAGAAACTTTTCCATA
TTGTACAGACCAGCAGAACTTCCGATTTTCCCAGCAGTCACTGCAATAGAGGGCATAATAGTTC
CAGTCTTTTGCAATCAATCAGGTATCTTTCTTAGAAACTATATAGAACCCATAATAAGAGACCA
GCAGATCACAGACAGTTTAAAGGGACATAAATTCATTTGATCTACTAATTTTAGGAAACACCTA
TTCAGAATAAGGCACTGTGGAAATACTATACAGTAACTCAAACATGGTTTAGTTGCTTGGGTGC
TCATCTAACTTCCCCTCCACATAAAAACAAATTTAAAAGAAAACACAACAAACAAACCAGAAAA
ACACATTTTCTTACACAGTTAATTTCTATATAATCACATATTCATCTCAATGCTTTTTAGTCTT
TAAACCAAACTTCTTCCTCATTTCATTCTGCACCTGTTAACCTAGCTTGTTTCCTCGTTCCAAA
ATTAATTAGGCAACTT

hide sequence

Protein Sequences


Protein RefSeqs	XP_038308613	(Get FASTA)	NCBI Sequence Viewer
	XP_038308614	(Get FASTA)	NCBI Sequence Viewer
	XP_038353701	(Get FASTA)	NCBI Sequence Viewer
	XP_038353702	(Get FASTA)	NCBI Sequence Viewer
	XP_038353703	(Get FASTA)	NCBI Sequence Viewer
	XP_038416173	(Get FASTA)	NCBI Sequence Viewer
	XP_038416174	(Get FASTA)	NCBI Sequence Viewer
	XP_038416175	(Get FASTA)	NCBI Sequence Viewer
	XP_038480222	(Get FASTA)	NCBI Sequence Viewer
	XP_038480223	(Get FASTA)	NCBI Sequence Viewer
	XP_038480224	(Get FASTA)	NCBI Sequence Viewer
	XP_038545973	(Get FASTA)	NCBI Sequence Viewer
	XP_038545974	(Get FASTA)	NCBI Sequence Viewer
	XP_038545975	(Get FASTA)	NCBI Sequence Viewer
	XP_532826	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000066944.1
	ENSCAFP00000068429.1
	ENSCAFP00030034081.1
	ENSCAFP00030034154.1
	ENSCAFP00040010602.1
	ENSCAFP00040010656.1
	ENSCAFP00845020662
	ENSCAFP00845020662.1
	ENSCAFP00845020671.1

RefSeq Acc Id:	XP_532826 ⟸ XM_532826
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0JIV6 (UniProtKB/TrEMBL), A0A8C0P2Z0 (UniProtKB/TrEMBL), A0A8I3RY92 (UniProtKB/TrEMBL), A0A8C0P749 (UniProtKB/TrEMBL), A0A8I3P2T1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSWLFPLTKSASSSAAGSPAGLTSLQQQKQRLIESLRNSHSSIAEIQKDVEYRLPFTVNNLTIN INILLPPQFPQEKPVISVYPPIQHHLMDKQGVYVTSPLVNNFTMHSDLGKIIQSLLDEFWKNPP VLAPSSTAFPYLYSNPSGLPPYASQGFPFLSPFPPQEPNRTVTSLSVADTISSSTTSYTPAKPA APFGILSNLPLPVPTTDTSAPISQNGFGYKMPDVPDTFPELSELSVSQLTDMNEQEEILLEQFL TLPQLKQIITDKDDLVKSIEELARKNLLLEPSLEAKRQTVLDKYELLTQLKSAFEKKMQRQHEL SESCSVSALQARLKVAAHEAEEESDNIAEDFLEGKTEIDDFLSSFMEKRTICHCRRAKEEKLQQ AITVHSQFHAPL hide sequence

Ensembl Acc Id:

ENSCAFP00000047788 ⟸ ENSCAFT00000070387

Ensembl Acc Id:

ENSCAFP00000034722 ⟸ ENSCAFT00000038933

RefSeq Acc Id:	XP_038353701 ⟸ XM_038497773
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038353702 ⟸ XM_038497774
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038353703 ⟸ XM_038497775
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038480222 ⟸ XM_038624294
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038480223 ⟸ XM_038624295
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038480224 ⟸ XM_038624296
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038545973 ⟸ XM_038690045
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0JIV6 (UniProtKB/TrEMBL), A0A8C0P2Z0 (UniProtKB/TrEMBL), A0A8I3RY92 (UniProtKB/TrEMBL), A0A8C0P749 (UniProtKB/TrEMBL), A0A8I3P2T1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038545974 ⟸ XM_038690046
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0P749 (UniProtKB/TrEMBL), A0A8I3P2T1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038545975 ⟸ XM_038690047
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0P749 (UniProtKB/TrEMBL), A0A8I3P2T1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038308613 ⟸ XM_038452685
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0P749 (UniProtKB/TrEMBL), A0A8I3P2T1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038308614 ⟸ XM_038452686
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0P749 (UniProtKB/TrEMBL), A0A8I3P2T1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038416173 ⟸ XM_038560245
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0JIV6 (UniProtKB/TrEMBL), A0A8C0P2Z0 (UniProtKB/TrEMBL), A0A8C0P749 (UniProtKB/TrEMBL), A0A8I3P2T1 (UniProtKB/TrEMBL), A0A8I3RY92 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038416174 ⟸ XM_038560246
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0P749 (UniProtKB/TrEMBL), A0A8I3P2T1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038416175 ⟸ XM_038560247
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0P749 (UniProtKB/TrEMBL), A0A8I3P2T1 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845020662 ⟸ ENSCAFT00845026207

Ensembl Acc Id:

ENSCAFP00845020671 ⟸ ENSCAFT00845026221

Protein Domains

VPS37 C-terminal

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000006905	Ensembl
	ENSCAFG00000053729	UniProtKB/TrEMBL
	ENSCAFG00030021244	UniProtKB/TrEMBL
	ENSCAFG00040006556	UniProtKB/TrEMBL
	ENSCAFG00845014638	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000095502.1	UniProtKB/TrEMBL
	ENSCAFT00000098927.1	UniProtKB/TrEMBL
	ENSCAFT00030039074.1	UniProtKB/TrEMBL
	ENSCAFT00030039161.1	UniProtKB/TrEMBL
	ENSCAFT00040012234.1	UniProtKB/TrEMBL
	ENSCAFT00040012293.1	UniProtKB/TrEMBL
	ENSCAFT00845026207	ENTREZGENE
	ENSCAFT00845026207.1	UniProtKB/TrEMBL
	ENSCAFT00845026221.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.287.660	UniProtKB/TrEMBL
	3.10.110.10	UniProtKB/TrEMBL
InterPro	ESCRT_assembly_dom	UniProtKB/TrEMBL
	Helix_hairpin_bin_sf	UniProtKB/TrEMBL
	Mod_r	UniProtKB/TrEMBL
	UBQ-conjugating_enzyme/RWD	UniProtKB/TrEMBL
NCBI Gene	VPS37A	ENTREZGENE
PANTHER	VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37	UniProtKB/TrEMBL
	VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37A	UniProtKB/TrEMBL
Pfam	Mod_r	UniProtKB/TrEMBL
PROSITE	VPS37_C	UniProtKB/TrEMBL
Superfamily-SCOP	SSF140111	UniProtKB/TrEMBL
	SSF54495	UniProtKB/TrEMBL
UniProt	A0A8C0JIV6	ENTREZGENE
	A0A8C0P2Z0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0P749	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3P2T1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3RY92	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:48287	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-10-08	VPS37A	VPS37A subunit of ESCRT-I	VPS37A	VPS37A, ESCRT-I subunit	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM