Vps37a (VPS37A subunit of ESCRT-I)

Gene: Vps37a (VPS37A subunit of ESCRT-I) Chinchilla lanigera

Analyze

Symbol:

Vps37a

Name:

VPS37A subunit of ESCRT-I

RGD ID:

8858566

Description:

INVOLVED IN ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (ortholog); ASSOCIATED WITH genetic disease (ortholog); hereditary spastic paraplegia (ortholog); hereditary spastic paraplegia 53 (ortholog); FOUND IN centrosome (ortholog); cytosol (ortholog); ESCRT I complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

vacuolar protein sorting 37 homolog A (S. cerevisiae); vacuolar protein sorting-associated protein 37A; VPS37A, ESCRT-I subunit

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955463	257,934 - 285,228 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955463	254,407 - 285,178 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

hereditary spastic paraplegia (ISO)

hereditary spastic paraplegia 53 (ISO)

transverse myelitis (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (ISO)

Cellular Component

centrosome (ISO)

cytosol (ISO)

ESCRT I complex (ISO)

intracellular membrane-bounded organelle (ISO)

nucleoplasm (ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Vps37a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955463	257,934 - 285,228 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955463	254,407 - 285,178 (-)	NCBI	ChiLan1.0	ChiLan1.0

VPS37A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	17,246,958 - 17,333,455 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	17,246,931 - 17,302,427 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	17,104,467 - 17,190,964 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	17,148,851 - 17,197,418 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	8	16,070,442 - 16,121,576 (+)	NCBI		Celera
Cytogenetic Map	8	p22	NCBI
HuRef	8	15,649,267 - 15,700,401 (+)	NCBI		HuRef
CHM1_1	8	17,305,854 - 17,356,966 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	17,514,555 - 17,601,063 (+)	NCBI		T2T-CHM13v2.0

Vps37a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	40,964,482 - 41,004,175 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	40,964,824 - 41,003,798 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	40,511,742 - 40,551,134 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	40,511,783 - 40,550,757 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	41,597,137 - 41,636,488 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	42,010,644 - 42,048,569 (+)	NCBI		MGSCv36	mm8
Celera	8	43,161,646 - 43,200,586 (+)	NCBI		Celera
Cytogenetic Map	8	A4	NCBI
cM Map	8	23.89	NCBI

Vps37a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	58,434,802 - 58,478,777 (-)	NCBI		GRCr8
mRatBN7.2	16	51,736,170 - 51,775,384 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	51,737,481 - 51,775,390 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	57,067,451 - 57,105,724 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	60,455,877 - 60,494,359 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	55,701,405 - 55,739,678 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	54,860,811 - 54,899,410 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	54,860,868 - 54,899,347 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	54,562,360 - 54,602,139 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	55,077,793 - 55,118,155 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	16	49,629,073 - 49,667,046 (-)	NCBI		Celera
Cytogenetic Map	16	q12.1	NCBI

VPS37A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	35,706,607 - 35,755,222 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	11,441,136 - 11,489,749 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	16,459,660 - 16,508,333 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	13,404,889 - 13,455,914 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	13,404,889 - 13,456,046 (+)	Ensembl	panpan1.1		panPan2

VPS37A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	40,571,892 - 40,624,359 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	40,571,892 - 40,620,885 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	41,069,350 - 41,120,875 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	42,625,545 - 42,677,128 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	42,625,538 - 42,682,796 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	40,718,884 - 40,770,708 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	41,262,142 - 41,313,723 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	41,455,590 - 41,507,257 (+)	NCBI		UU_Cfam_GSD_1.0

Vps37a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	38,798,354 - 38,836,225 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936573	6,306,536 - 6,340,271 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936573	6,306,218 - 6,343,544 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

VPS37A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	4,949,644 - 4,988,074 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	4,949,632 - 5,014,842 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	5,343,722 - 5,356,880 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

VPS37A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	15,333,570 - 15,384,451 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	15,333,557 - 15,374,678 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666052	26,892,933 - 26,945,463 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Vps37a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624769	22,021,638 - 22,046,794 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624769	22,022,808 - 22,047,068 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005398335	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005398336	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005398337	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01049479	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCQ01122206	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000000936 ⟹ ENSCLAP00000000899

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955463	257,934 - 285,228 (-)	Ensembl

RefSeq Acc Id:

XM_005398335 ⟹ XP_005398392

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955463	254,407 - 285,178 (-)	NCBI

Sequence:

show sequence

CACGCCGGTGACGGAGGCTGGGGTGGTGGAGTGCTGGGCCGGCAGGCTGTGTCTGACTGGCTGG
CTCGGTCATCTGGGCCGCGAAGCTGGGGCTGCCCGTCCCGGAAGGCAAGTTGCCCTCTCCAGCT
GTTTGCACTGGTGGAGCGTCCCCCAGAAGCCGGCGCCGCGGCCGGACTTCCTTAGCGGGGACGC
CGTCCCGCAGCGCCGGGAGCCGGCGCCTGGGCCCGCGCGTCCGTCTCTGAAGATCGGCCGGCTG
AGCAGCTGGGAGGAGCAGGCCGGAGGCTTCTGGGGCCTGGGGCCCGGGGACCCCGGGAGAATGA
GCTGGCTCTTTCCCCTGAGCAAGAGCGGCGCCTCCTCCGCGGCCGGGTCCCCCGGGGGCCTCAC
CAGCCTCCAGCAGCAGAAGCAGCGCCTGATCGAGTCGCTCCGCAGCTCGCACTCCAGTATAGCT
GAAATACAGAAAGATGTGGAATATAGATTGCCGTTCACTGTAAACAACCTGACAATTAACATTA
ATATATTACTTCCTCCACAGTTTCCTCAGGAAAAACCAGTGATCAGTGTTTATCCACCAATACG
ACATCACTTAATGGATAAACAAGGAGTATACGTTACCTCTCCATTAGTAAGCAATTTTACAATG
CACTCAGATCTTGGAAAAATTATTCAGAGTCTGTTGGATGAATTCTGGAAGAATCCTCCAGTTT
TAGCTCCTACTTCAACAGCATTTCCATACTTGTATAGTAACTCAGGTGGGATGCCTCCTTATGC
ATCTCAGCGCTTTCCATTTCTTCCTCCATATCCTCCACAAGAAGCTAACAGGACTATCACTTCT
TTATCTGTTGCTGACACTGTTTCTTCTTCAACAACGAGTTATACTACAGCCAAGCCTGCTGCTC
CTTCGTTTGGTGTCCTTTCAAGTCTGCCTTTGCCCATCCCCACAACAGACAGTTCAACACCGAT
AAGCCAAAATGGTTTTGGTTACAAGATGCCAGATGTTCCTGATGCATTTCCAGAACTCTCAGAA
CTAAGTGTGTCACAACTCACAGATATGAATGAACAAGAGGAAGTATTACTAGAACAGTTTCTGA
CTTTGCCTCAACTAAAACAAATTATTACTGACAAGGATGACTTAGTAAAAAGTATTGAGGAATT
AGCAAGAAAAAATCTCCTTTTGGAACCCAGTTTAGAAGCAAAAAGGCAAACTGTTTTGGATAAG
TATGAGGTACTTACACAAATGAAATCTGCTTTTGAAAAGAAGATGCAAAGGCAGCATGAACTTA
GTGAGAGCTGTAGTGCAAGTACCCTACAGGCAAGATTGAAAGTAGCTGCACATGAAGCTGAGGA
AGAATCTGATAATATTGCTGAAGATTTCTTGGAGGGAAAAACTGAAATAGATGATTTTCTCAGT
AGCTTCATGGAAAAGAGAACAATTTGCCATTGTAGAAGAGCCAAGGAAGAGAAACTTCAGCAGG
TGATCGCAATGCACAGCCATTTTCATGCTCCTTTATAGATTTTCCTGAAAACATGAACTGCCAA
GAGAAAAATGGGACACAGAACTAAGCACATTGTTTTATATTTATGATTGGCAAGTTGGCATTTC
ATCACAGGGGCTGAATTCACAGATATACAATACTATATAGATTGTATATAGAACTGAGACTGAT
TTTGTACAGATTAGGATGATTGCTATGATCTTTGAGGAATTTTTCTGCACTATTTGCACTAAAA
ATGTTTATTTATTGTTGATAAATCCTATCATATTTAAACTTCATTGCTATTCCTCCTCTTGATT
AAATGCCTATGCATGTAGTTTTAGCTAGTTTGCAATATTTTATAAAGCTACTTAATTTAAATTT
GTAGTTTTAATTTGAAGTGGCATCATTTCTTTGTTAGGAATTATGTGTTAGATTATTTTACTCT
CAGCCTTTCATGAAAAACTATTTTCAACTGTGGAAAGATACTTTTTTTTCTTTTTGGTTTTCTT
TCTGGATGATAAATGCAATTTATTTTTAACTATTTGTAGTGTCAGGAAACACCAAATCTCCCCA
ATATGCCATCTCAAGTCATAACTTTTAATACTTACAATAAACCAAGAGAATAAACCA

hide sequence

RefSeq Acc Id:

XM_005398336 ⟹ XP_005398393

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955463	254,407 - 285,178 (-)	NCBI

Sequence:

show sequence

CACGCCGGTGACGGAGGCTGGGGTGGTGGAGTGCTGGGCCGGCAGGCTGTGTCTGACTGGCTGG
CTCGGTCATCTGGGCCGCGAAGCTGGGGCTGCCCGTCCCGGAAGGCAAGTTGCCCTCTCCAGCT
GTTTGCACTGGTGGAGCGTCCCCCAGAAGCCGGCGCCGCGGCCGGACTTCCTTAGCGGGGACGC
CGTCCCGCAGCGCCGGGAGCCGGCGCCTGGGCCCGCGCGTCCGTCTCTGAAGATCGGCCGGCTG
AGCAGCTGGGAGGAGCAGGCCGGAGGCTTCTGGGGCCTGGGGCCCGGGGACCCCGGGAGAATGA
GCTGGCTCTTTCCCCTGAGCAAGAGCGGCGCCTCCTCCGCGGCCGGGTCCCCCGGGGGCCTCAC
CAGCCTCCAGCAGCAGAAGCAGCGCCTGATCGAGTCGCTCCGCAGCTCGCACTCCAGATTACTT
CCTCCACAGTTTCCTCAGGAAAAACCAGTGATCAGTGTTTATCCACCAATACGACATCACTTAA
TGGATAAACAAGGAGTATACGTTACCTCTCCATTAGTAAGCAATTTTACAATGCACTCAGATCT
TGGAAAAATTATTCAGAGTCTGTTGGATGAATTCTGGAAGAATCCTCCAGTTTTAGCTCCTACT
TCAACAGCATTTCCATACTTGTATAGTAACTCAGGTGGGATGCCTCCTTATGCATCTCAGCGCT
TTCCATTTCTTCCTCCATATCCTCCACAAGAAGCTAACAGGACTATCACTTCTTTATCTGTTGC
TGACACTGTTTCTTCTTCAACAACGAGTTATACTACAGCCAAGCCTGCTGCTCCTTCGTTTGGT
GTCCTTTCAAGTCTGCCTTTGCCCATCCCCACAACAGACAGTTCAACACCGATAAGCCAAAATG
GTTTTGGTTACAAGATGCCAGATGTTCCTGATGCATTTCCAGAACTCTCAGAACTAAGTGTGTC
ACAACTCACAGATATGAATGAACAAGAGGAAGTATTACTAGAACAGTTTCTGACTTTGCCTCAA
CTAAAACAAATTATTACTGACAAGGATGACTTAGTAAAAAGTATTGAGGAATTAGCAAGAAAAA
ATCTCCTTTTGGAACCCAGTTTAGAAGCAAAAAGGCAAACTGTTTTGGATAAGTATGAGGTACT
TACACAAATGAAATCTGCTTTTGAAAAGAAGATGCAAAGGCAGCATGAACTTAGTGAGAGCTGT
AGTGCAAGTACCCTACAGGCAAGATTGAAAGTAGCTGCACATGAAGCTGAGGAAGAATCTGATA
ATATTGCTGAAGATTTCTTGGAGGGAAAAACTGAAATAGATGATTTTCTCAGTAGCTTCATGGA
AAAGAGAACAATTTGCCATTGTAGAAGAGCCAAGGAAGAGAAACTTCAGCAGGTGATCGCAATG
CACAGCCATTTTCATGCTCCTTTATAGATTTTCCTGAAAACATGAACTGCCAAGAGAAAAATGG
GACACAGAACTAAGCACATTGTTTTATATTTATGATTGGCAAGTTGGCATTTCATCACAGGGGC
TGAATTCACAGATATACAATACTATATAGATTGTATATAGAACTGAGACTGATTTTGTACAGAT
TAGGATGATTGCTATGATCTTTGAGGAATTTTTCTGCACTATTTGCACTAAAAATGTTTATTTA
TTGTTGATAAATCCTATCATATTTAAACTTCATTGCTATTCCTCCTCTTGATTAAATGCCTATG
CATGTAGTTTTAGCTAGTTTGCAATATTTTATAAAGCTACTTAATTTAAATTTGTAGTTTTAAT
TTGAAGTGGCATCATTTCTTTGTTAGGAATTATGTGTTAGATTATTTTACTCTCAGCCTTTCAT
GAAAAACTATTTTCAACTGTGGAAAGATACTTTTTTTTCTTTTTGGTTTTCTTTCTGGATGATA
AATGCAATTTATTTTTAACTATTTGTAGTGTCAGGAAACACCAAATCTCCCCAATATGCCATCT
CAAGTCATAACTTTTAATACTTACAATAAACCAAGAGAATAAACCA

hide sequence

RefSeq Acc Id:

XM_005398337 ⟹ XP_005398394

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955463	254,407 - 285,178 (-)	NCBI

Sequence:

show sequence

CACGCCGGTGACGGAGGCTGGGGTGGTGGAGTGCTGGGCCGGCAGGCTGTGTCTGACTGGCTGG
CTCGGTCATCTGGGCCGCGAAGCTGGGGCTGCCCGTCCCGGAAGGCAAGTTGCCCTCTCCAGCT
GTTTGCACTGGTGGAGCGTCCCCCAGAAGCCGGCGCCGCGGCCGGACTTCCTTAGCGGGGACGC
CGTCCCGCAGCGCCGGGAGCCGGCGCCTGGGCCCGCGCGTCCGTCTCTGAAGATCGGCCGGCTG
AGCAGCTGGGAGGAGCAGGCCGGAGGCTTCTGGGGCCTGGGGCCCGGGGACCCCGGGAGAATGA
GCTGGCTCTTTCCCCTGAGCAAGAGCGGCGCCTCCTCCGCGGCCGGGTCCCCCGGGGGCCTCAC
CAGCCTCCAGCAGCAGAAGCAGCGCCTGATCGAGTCGCTCCGCAGCTCGCACTCCAGTATAGCT
GAAATACAGAAAGATGTGGAATATAGATTGCCGTTCACTGTAAACAACCTGACAATTAACATTA
ATATATTACTTCCTCCACAGTTTCCTCAGGAAAAACCAGTGATCAGTGTTTATCCACCAATACG
ACATCACTTAATGGATAAACAAGGAGTATACGTTACCTCTCCATTAGTAAGCAATTTTACAATG
CACTCAGATCTTGGAAAAATTATTCAGAGTCTGTTGGATGAATTCTGGAAGAATCCTCCAGTTT
TAGCTCCTACTTCAACAGCATTTCCATACTTGTATAGTAACTCAGGTGGGATGCCTCCTTATGC
ATCTCAGCGCTTTCCATTTCTTCCTCCATATCCTCCACAAGAAGCTAACAGGACTATCACTTCT
TTATCTGTTGCTGACACTGTTTCTTCTTCAACAACGAGTTATACTACAGCCAAGCCTGCTGCTC
CTTCGTTTGGTGTCCTTTCAAGTCTGCCTTTGCCCATCCCCACAACAGACAGTTCAACACCGAT
AAGCCAAAATGGTTTTGGTTACAAGATGCCAGATGTTCCTGATGCATTTCCAGAACTCTCAGAA
CTAAGTGTGTCACAACTCACAGATATGAATGAACAAGAGGAAGTATTACTAGAACAGTTTCTGA
CTTTGCCTCAACTAAAACAAATTATTACTGACAAGGATGACTTAGTAAAAAGTATTGAGGAATT
AGCAAGAAAAAATCTCCTTTTGGAACCCAGTTTAGAAGCAAAAAGGCAAACTGTTTTGGATAAG
TATGAGGTACTTACACAAATGAAATCTGCTTTTGAAAAGAAGATGCAAAGGCAGCATGAACTTA
GTGAGATTTGCCATTGTAGAAGAGCCAAGGAAGAGAAACTTCAGCAGGTGATCGCAATGCACAG
CCATTTTCATGCTCCTTTATAGATTTTCCTGAAAACATGAACTGCCAAGAGAAAAATGGGACAC
AGAACTAAGCACATTGTTTTATATTTATGATTGGCAAGTTGGCATTTCATCACAGGGGCTGAAT
TCACAGATATACAATACTATATAGATTGTATATAGAACTGAGACTGATTTTGTACAGATTAGGA
TGATTGCTATGATCTTTGAGGAATTTTTCTGCACTATTTGCACTAAAAATGTTTATTTATTGTT
GATAAATCCTATCATATTTAAACTTCATTGCTATTCCTCCTCTTGATTAAATGCCTATGCATGT
AGTTTTAGCTAGTTTGCAATATTTTATAAAGCTACTTAATTTAAATTTGTAGTTTTAATTTGAA
GTGGCATCATTTCTTTGTTAGGAATTATGTGTTAGATTATTTTACTCTCAGCCTTTCATGAAAA
ACTATTTTCAACTGTGGAAAGATACTTTTTTTTCTTTTTGGTTTTCTTTCTGGATGATAAATGC
AATTTATTTTTAACTATTTGTAGTGTCAGGAAACACCAAATCTCCCCAATATGCCATCTCAAGT
CATAACTTTTAATACTTACAATAAACCAAGAGAATAAACCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005398392	(Get FASTA)	NCBI Sequence Viewer
	XP_005398393	(Get FASTA)	NCBI Sequence Viewer
	XP_005398394	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000000899
	ENSCLAP00000000899.1

RefSeq Acc Id:

XP_005398393 ⟸ XM_005398336

- Peptide Label:

isoform X2

- Sequence:

show sequence

MSWLFPLSKSGASSAAGSPGGLTSLQQQKQRLIESLRSSHSRLLPPQFPQEKPVISVYPPIRHH
LMDKQGVYVTSPLVSNFTMHSDLGKIIQSLLDEFWKNPPVLAPTSTAFPYLYSNSGGMPPYASQ
RFPFLPPYPPQEANRTITSLSVADTVSSSTTSYTTAKPAAPSFGVLSSLPLPIPTTDSSTPISQ
NGFGYKMPDVPDAFPELSELSVSQLTDMNEQEEVLLEQFLTLPQLKQIITDKDDLVKSIEELAR
KNLLLEPSLEAKRQTVLDKYEVLTQMKSAFEKKMQRQHELSESCSASTLQARLKVAAHEAEEES
DNIAEDFLEGKTEIDDFLSSFMEKRTICHCRRAKEEKLQQVIAMHSHFHAPL

hide sequence

RefSeq Acc Id:

XP_005398394 ⟸ XM_005398337

- Peptide Label:

isoform X3

- Sequence:

show sequence

MSWLFPLSKSGASSAAGSPGGLTSLQQQKQRLIESLRSSHSSIAEIQKDVEYRLPFTVNNLTIN
INILLPPQFPQEKPVISVYPPIRHHLMDKQGVYVTSPLVSNFTMHSDLGKIIQSLLDEFWKNPP
VLAPTSTAFPYLYSNSGGMPPYASQRFPFLPPYPPQEANRTITSLSVADTVSSSTTSYTTAKPA
APSFGVLSSLPLPIPTTDSSTPISQNGFGYKMPDVPDAFPELSELSVSQLTDMNEQEEVLLEQF
LTLPQLKQIITDKDDLVKSIEELARKNLLLEPSLEAKRQTVLDKYEVLTQMKSAFEKKMQRQHE
LSEICHCRRAKEEKLQQVIAMHSHFHAPL

hide sequence

RefSeq Acc Id:	XP_005398392 ⟸ XM_005398335
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C2UJ38 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSWLFPLSKSGASSAAGSPGGLTSLQQQKQRLIESLRSSHSSIAEIQKDVEYRLPFTVNNLTIN INILLPPQFPQEKPVISVYPPIRHHLMDKQGVYVTSPLVSNFTMHSDLGKIIQSLLDEFWKNPP VLAPTSTAFPYLYSNSGGMPPYASQRFPFLPPYPPQEANRTITSLSVADTVSSSTTSYTTAKPA APSFGVLSSLPLPIPTTDSSTPISQNGFGYKMPDVPDAFPELSELSVSQLTDMNEQEEVLLEQF LTLPQLKQIITDKDDLVKSIEELARKNLLLEPSLEAKRQTVLDKYEVLTQMKSAFEKKMQRQHE LSESCSASTLQARLKVAAHEAEEESDNIAEDFLEGKTEIDDFLSSFMEKRTICHCRRAKEEKLQ QVIAMHSHFHAPL hide sequence

RefSeq Acc Id:

ENSCLAP00000000899 ⟸ ENSCLAT00000000936

Protein Domains

VPS37 C-terminal

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000000699	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000000936	ENTREZGENE
	ENSCLAT00000000936.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.287.660	UniProtKB/TrEMBL
	3.10.110.10	UniProtKB/TrEMBL
InterPro	ESCRT_assembly_dom	UniProtKB/TrEMBL
	Helix_hairpin_bin_sf	UniProtKB/TrEMBL
	Mod_r	UniProtKB/TrEMBL
	UBQ-conjugating_enzyme/RWD	UniProtKB/TrEMBL
NCBI Gene	Vps37a	ENTREZGENE
PANTHER	VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37	UniProtKB/TrEMBL
	VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37A	UniProtKB/TrEMBL
Pfam	Mod_r	UniProtKB/TrEMBL
PROSITE	VPS37_C	UniProtKB/TrEMBL
Superfamily-SCOP	SSF140111	UniProtKB/TrEMBL
	SSF54495	UniProtKB/TrEMBL
UniProt	A0A8C2UJ38	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-02-05	Vps37a	VPS37A subunit of ESCRT-I		VPS37A, ESCRT-I subunit	Symbol and/or name change	5135510	APPROVED
2016-08-03	Vps37a	VPS37A, ESCRT-I subunit		vacuolar protein sorting 37 homolog A (S. cerevisiae)	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM