AP1G1 (adaptor related protein complex 1 subunit gamma 1) - Rat Genome Database

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Gene: AP1G1 (adaptor related protein complex 1 subunit gamma 1) Canis lupus familiaris
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Symbol: AP1G1 (Ensembl: PHLPP2)
Name: adaptor related protein complex 1 subunit gamma 1
RGD ID: 12258685
Description: ENCODES a protein that exhibits collagen binding (ortholog); GTP-dependent protein binding (ortholog); kinesin binding (ortholog); INVOLVED IN endosome to melanosome transport (ortholog); Golgi to lysosome transport (ortholog); positive regulation of natural killer cell degranulation (ortholog); ASSOCIATED WITH autosomal dominant dyskeratosis congenita 6 (ortholog); genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN clathrin-coated vesicle (ortholog); cytosol (ortholog); perinuclear region of cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: adaptor related protein complex 1 gamma 1 subunit; AP-1 complex subunit gamma-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1577,512,865 - 77,589,136 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl577,432,517 - 77,565,801 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha577,471,192 - 77,550,461 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0577,949,221 - 78,028,610 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl577,869,730 - 78,028,575 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1577,769,242 - 77,848,763 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0577,592,241 - 77,671,470 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0578,091,430 - 78,170,707 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
AP1G1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1577,512,865 - 77,589,136 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl577,432,517 - 77,565,801 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha577,471,192 - 77,550,461 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0577,949,221 - 78,028,610 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl577,869,730 - 78,028,575 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1577,769,242 - 77,848,763 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0577,592,241 - 77,671,470 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0578,091,430 - 78,170,707 (-)NCBIUU_Cfam_GSD_1.0
AP1G1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381671,729,000 - 71,808,834 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1671,729,000 - 71,809,201 (-)EnsemblGRCh38hg38GRCh38
GRCh371671,762,903 - 71,842,737 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361670,320,404 - 70,400,477 (-)NCBINCBI36Build 36hg18NCBI36
Build 341670,320,415 - 70,400,477NCBI
Celera1656,079,081 - 56,139,681 (-)NCBICelera
Cytogenetic Map16q22.2NCBI
HuRef1657,530,455 - 57,610,654 (-)NCBIHuRef
CHM1_11673,175,717 - 73,255,849 (-)NCBICHM1_1
T2T-CHM13v2.01677,546,146 - 77,626,032 (-)NCBIT2T-CHM13v2.0
Ap1g1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398110,505,215 - 110,590,842 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8110,505,186 - 110,590,836 (+)EnsemblGRCm39 Ensembl
GRCm388109,778,583 - 109,864,210 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8109,778,554 - 109,864,204 (+)EnsemblGRCm38mm10GRCm38
MGSCv378112,302,540 - 112,384,835 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368112,667,839 - 112,750,487 (+)NCBIMGSCv36mm8
Celera8114,004,323 - 114,082,583 (+)NCBICelera
Cytogenetic Map8D3NCBI
cM Map857.26NCBI
Ap1g1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81954,654,101 - 54,740,586 (+)NCBIGRCr8
mRatBN7.21937,744,633 - 37,831,134 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1937,744,633 - 37,829,167 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1944,557,067 - 44,643,433 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01945,210,401 - 45,296,775 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01947,520,023 - 47,606,391 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01941,805,252 - 41,860,076 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01952,628,652 - 52,684,797 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41939,676,021 - 39,734,854 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11939,730,027 - 39,738,578 (+)NCBI
Celera1937,174,653 - 37,231,881 (+)NCBICelera
Cytogenetic Map19q12NCBI
Ap1g1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554844,430,461 - 4,510,497 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554844,430,461 - 4,511,368 (-)NCBIChiLan1.0ChiLan1.0
AP1G1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21882,349,579 - 82,430,963 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11688,278,156 - 88,356,757 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01653,201,859 - 53,282,437 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11671,568,856 - 71,648,744 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1671,568,863 - 71,648,744 (-)Ensemblpanpan1.1panPan2
Ap1g1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934937,525,971 - 37,605,861 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647521,983,248 - 22,063,181 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647521,983,248 - 22,063,133 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AP1G1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl614,719,959 - 14,809,491 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1614,719,949 - 14,809,821 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2614,338,265 - 14,426,133 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AP1G1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1554,850,831 - 54,944,915 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl554,850,694 - 54,944,900 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604717,652,522 - 17,740,544 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ap1g1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474613,997,681 - 14,081,197 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474613,997,903 - 14,081,140 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in AP1G1
620 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


RefSeq Acc Id: XM_003434707   ⟹   XP_003434755
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1577,512,865 - 77,589,136 (-)NCBI
Dog10K_Boxer_Tasha577,471,192 - 77,550,461 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038477227   ⟹   XP_038333155
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1577,769,242 - 77,848,763 (-)NCBI
RefSeq Acc Id: XM_038477228   ⟹   XP_038333156
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1577,769,242 - 77,848,763 (-)NCBI
RefSeq Acc Id: XM_038538429   ⟹   XP_038394357
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0578,091,430 - 78,170,707 (-)NCBI
RefSeq Acc Id: XM_038538430   ⟹   XP_038394358
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0578,091,430 - 78,170,707 (-)NCBI
RefSeq Acc Id: XM_038602549   ⟹   XP_038458477
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0577,592,241 - 77,671,470 (-)NCBI
RefSeq Acc Id: XM_038602550   ⟹   XP_038458478
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0577,592,241 - 77,671,470 (-)NCBI
RefSeq Acc Id: XM_038667156   ⟹   XP_038523084
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0577,949,221 - 78,028,610 (-)NCBI
RefSeq Acc Id: XM_038667157   ⟹   XP_038523085
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0577,949,221 - 78,028,610 (-)NCBI
RefSeq Acc Id: XM_857413   ⟹   XP_862506
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1577,512,865 - 77,589,136 (-)NCBI
Dog10K_Boxer_Tasha577,471,192 - 77,550,461 (-)NCBI
Sequence:
RefSeq Acc Id: XP_862506   ⟸   XM_857413
- Peptide Label: isoform X2
- UniProtKB: A0A8C0L7Y2 (UniProtKB/TrEMBL),   A0A8C0T491 (UniProtKB/TrEMBL),   A0A8I3RUL0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003434755   ⟸   XM_003434707
- Peptide Label: isoform X1
- UniProtKB: A0A8C0T135 (UniProtKB/TrEMBL),   A0A8I3N275 (UniProtKB/TrEMBL),   A0A8C0T491 (UniProtKB/TrEMBL),   A0A8I3RUL0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038333156   ⟸   XM_038477228
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038333155   ⟸   XM_038477227
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038458478   ⟸   XM_038602550
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038458477   ⟸   XM_038602549
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038523085   ⟸   XM_038667157
- Peptide Label: isoform X2
- UniProtKB: A0A8C0L7Y2 (UniProtKB/TrEMBL),   A0A8C0T491 (UniProtKB/TrEMBL),   A0A8I3RUL0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038523084   ⟸   XM_038667156
- Peptide Label: isoform X1
- UniProtKB: A0A8C0T135 (UniProtKB/TrEMBL),   A0A8I3N275 (UniProtKB/TrEMBL),   A0A8C0T491 (UniProtKB/TrEMBL),   A0A8I3RUL0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038394358   ⟸   XM_038538430
- Peptide Label: isoform X2
- UniProtKB: A0A8C0L7Y2 (UniProtKB/TrEMBL),   A0A8C0T491 (UniProtKB/TrEMBL),   A0A8I3RUL0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038394357   ⟸   XM_038538429
- Peptide Label: isoform X1
- UniProtKB: A0A8C0T135 (UniProtKB/TrEMBL),   A0A8C0T491 (UniProtKB/TrEMBL),   A0A8I3N275 (UniProtKB/TrEMBL),   A0A8I3RUL0 (UniProtKB/TrEMBL)
Protein Domains
GAE   PPM-type phosphatase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000020189 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030009271 UniProtKB/TrEMBL
  ENSCAFG00030009473 UniProtKB/TrEMBL
  ENSCAFG00040017922 UniProtKB/TrEMBL
  ENSCAFG00040018100 UniProtKB/TrEMBL
  ENSCAFG00845005939 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000032156.5 UniProtKB/TrEMBL
  ENSCAFT00000032187.5 UniProtKB/TrEMBL
  ENSCAFT00000060950.2 UniProtKB/TrEMBL
  ENSCAFT00000064591.2 UniProtKB/TrEMBL
  ENSCAFT00000080609.2 UniProtKB/TrEMBL
  ENSCAFT00000100975.1 UniProtKB/TrEMBL
  ENSCAFT00030017311.1 UniProtKB/TrEMBL
  ENSCAFT00030017577.1 UniProtKB/TrEMBL
  ENSCAFT00030017672.1 UniProtKB/TrEMBL
  ENSCAFT00030017796.1 UniProtKB/TrEMBL
  ENSCAFT00040033196.1 UniProtKB/TrEMBL
  ENSCAFT00040033480.1 UniProtKB/TrEMBL
  ENSCAFT00040033527.1 UniProtKB/TrEMBL
  ENSCAFT00040033642.1 UniProtKB/TrEMBL
  ENSCAFT00845010564.1 UniProtKB/TrEMBL
  ENSCAFT00845010675.1 UniProtKB/TrEMBL
  ENSCAFT00845010862.1 UniProtKB/TrEMBL
  ENSCAFT00845010993 ENTREZGENE
  ENSCAFT00845010993.1 UniProtKB/TrEMBL
  ENSCAFT00845011023 ENTREZGENE
  ENSCAFT00845011023.1 UniProtKB/TrEMBL
  ENSCAFT00845011063.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  2.60.40.1230 UniProtKB/TrEMBL
  3.60.40.10 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro Adaptor_Complx_Large_Subunit UniProtKB/TrEMBL
  AP1_complex_gsu UniProtKB/TrEMBL
  ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Clathrin/coatomer_adapt-like_N UniProtKB/TrEMBL
  Clathrin_a/b/g-adaptin_app_Ig UniProtKB/TrEMBL
  Clathrin_app_Ig-like_sf UniProtKB/TrEMBL
  GAE_dom UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  LRR_domain-containing UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PPM-type_dom_sf UniProtKB/TrEMBL
  PPM-type_phosphatase_dom UniProtKB/TrEMBL
  RA_PHLPP-like UniProtKB/TrEMBL
KEGG Report cfa:479666 UniProtKB/TrEMBL
NCBI Gene AP1G1 ENTREZGENE
PANTHER ADAPTIN, ALPHA/GAMMA/EPSILON UniProtKB/TrEMBL
  AP-1 COMPLEX SUBUNIT GAMMA-1 UniProtKB/TrEMBL
  PH DOMAIN AND LEUCINE-RICH REPEAT PROTEIN PHOSPHATASE 2 UniProtKB/TrEMBL
  PTHR48051 UniProtKB/TrEMBL
Pfam Adaptin_N UniProtKB/TrEMBL
  Alpha_adaptinC2 UniProtKB/TrEMBL
  LRR_1 UniProtKB/TrEMBL
  LRR_8 UniProtKB/TrEMBL
  PP2C UniProtKB/TrEMBL
  RA_3 UniProtKB/TrEMBL
PIRSF AP1_complex_gamma UniProtKB/TrEMBL
PROSITE GAE UniProtKB/TrEMBL
  LRR UniProtKB/TrEMBL
  PPM_2 UniProtKB/TrEMBL
SMART Alpha_adaptinC2 UniProtKB/TrEMBL
  LRR_BAC UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
  PP2Cc UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
  PH domain-like UniProtKB/TrEMBL
  SSF48371 UniProtKB/TrEMBL
  SSF49348 UniProtKB/TrEMBL
  SSF81606 UniProtKB/TrEMBL
UniProt A0A8C0L7Y2 ENTREZGENE
  A0A8C0RGK7_CANLF UniProtKB/TrEMBL
  A0A8C0SZI3_CANLF UniProtKB/TrEMBL
  A0A8C0T135 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0T281_CANLF UniProtKB/TrEMBL
  A0A8C0T491 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MWU6_CANLF UniProtKB/TrEMBL
  A0A8I3MXZ1_CANLF UniProtKB/TrEMBL
  A0A8I3MZR3_CANLF UniProtKB/TrEMBL
  A0A8I3MZX3_CANLF UniProtKB/TrEMBL
  A0A8I3N275 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RUL0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NTS6_CANLF UniProtKB/TrEMBL
  A0A8P0SZG8_CANLF UniProtKB/TrEMBL
  A0A8P0T2B3_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:37952 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-01 AP1G1  adaptor related protein complex 1 subunit gamma 1    adaptor related protein complex 1 gamma 1 subunit  Symbol and/or name change 5135510 APPROVED