TGM2 (transglutaminase 2) - Rat Genome Database

Name: TGM2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: TGM2 (transglutaminase 2) Canis lupus familiaris

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Symbol:

TGM2

Name:

transglutaminase 2

RGD ID:

12257602

Description:

ENCODES a protein that exhibits GTP binding (ortholog); identical protein binding (ortholog); phospholipase binding (ortholog); INVOLVED IN blood vessel remodeling (ortholog); branching involved in salivary gland morphogenesis (ortholog); dopamine secretion (ortholog); PARTICIPATES IN eicosanoid signaling pathway; ASSOCIATED WITH Brain Neoplasms (ortholog); Breast Neoplasms (ortholog); celiac disease (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog); plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

protein-glutamine gamma-glutamyltransferase 2; transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TGM2 (transglutaminase 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Tgm2 (transglutaminase 2, C polypeptide)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Tgm2 (transglutaminase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tgm2 (transglutaminase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TGM2 (transglutaminase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tgm2 (transglutaminase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TGM2 (transglutaminase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TGM2 (transglutaminase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tgm2 (transglutaminase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	26,631,339 - 26,662,723 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	26,628,009 - 26,663,840 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	26,277,181 - 26,308,444 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	27,327,862 - 27,359,126 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	27,295,164 - 27,359,267 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	26,602,350 - 26,633,607 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	26,710,189 - 26,741,409 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	27,198,294 - 27,229,594 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Brain Neoplasms (ISO)

Breast Neoplasms (ISO)

celiac disease (ISO)

Esophageal Neoplasms (ISO)

focal epilepsy (ISO)

glioblastoma (ISO)

hypertension (ISO)

Left Ventricular Hypertrophy (ISO)

liver cirrhosis (ISO)

maturity-onset diabetes of the young (ISO)

osteoarthritis (ISO)

pancreatic cancer (ISO)

renal cell carcinoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

apoptotic cell clearance (IEA)

blood vessel remodeling (ISO)

branching involved in salivary gland morphogenesis (IEA,ISO)

cellular response to cocaine (IEA)

cellular response to dopamine (IEA)

cellular response to serotonin (IEA)

chromatin remodeling (IEA)

dopamine secretion (IEA,ISO)

G protein-coupled receptor signaling pathway (ISO)

gene expression (IEA,ISO)

isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine (ISO)

negative regulation of endoplasmic reticulum calcium ion concentration (IEA)

peptide cross-linking (ISO)

phospholipase C-activating G protein-coupled receptor signaling pathway (IEA,ISO)

positive regulation of apoptotic process (IEA,ISO)

positive regulation of canonical NF-kappaB signal transduction (ISO)

positive regulation of cell adhesion (IEA)

positive regulation of mitochondrial calcium ion concentration (IEA)

positive regulation of neurogenesis (IEA)

positive regulation of smooth muscle cell proliferation (ISO)

positive regulation of sprouting angiogenesis (IEA)

protein deamination (ISO)

protein homooligomerization (ISO)

proteolysis (IEA)

regulation of apoptotic cell clearance (IEA)

regulation of apoptotic process (IEA)

salivary gland cavitation (IEA,ISO)

Cellular Component

chromatin (IEA)

chromosome (IEA)

cytoplasm (IEA)

cytosol (IEA)

endoplasmic reticulum (IEA)

extracellular matrix (IEA)

extracellular region (IEA)

mitochondrion (IEA)

nucleosome (IEA)

nucleus (IEA)

perinuclear region of cytoplasm (ISO)

plasma membrane (IEA,ISO)

Molecular Function

acyltransferase activity (IEA)

calcium ion binding (IEA)

GTP binding (IEA,ISO)

histone dopaminyltransferase activity (IEA)

histone serotonyltransferase activity (IEA)

identical protein binding (ISO)

metal ion binding (IEA)

peptidase activity (IEA)

peptide histaminyltransferase activity (IEA)

phospholipase binding (ISO)

protein binding (ISO)

protein domain specific binding (ISO)

protein-glutamine gamma-glutamyltransferase activity (IEA)

protein-glutamine glutaminase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

eicosanoid signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

TGM2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	26,631,339 - 26,662,723 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	26,628,009 - 26,663,840 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	26,277,181 - 26,308,444 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	27,327,862 - 27,359,126 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	27,295,164 - 27,359,267 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	26,602,350 - 26,633,607 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	26,710,189 - 26,741,409 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	27,198,294 - 27,229,594 (-)	NCBI		UU_Cfam_GSD_1.0

TGM2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	38,127,385 - 38,168,475 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	38,127,385 - 38,166,578 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	20	36,755,787 - 36,794,910 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	36,190,277 - 36,227,114 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	20	36,199,764 - 36,227,114	NCBI
Celera	20	33,465,637 - 33,502,475 (-)	NCBI		Celera
Cytogenetic Map	20	q11.23	NCBI
HuRef	20	33,493,671 - 33,530,533 (-)	NCBI		HuRef
CHM1_1	20	36,660,115 - 36,696,950 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	20	39,852,468 - 39,893,578 (-)	NCBI		T2T-CHM13v2.0

Tgm2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	157,958,325 - 157,988,312 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	157,958,322 - 157,988,356 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	158,116,405 - 158,146,392 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	158,116,402 - 158,146,436 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	157,942,141 - 157,972,128 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	157,807,846 - 157,837,833 (-)	NCBI		MGSCv36	mm8
Celera	2	164,061,515 - 164,091,498 (-)	NCBI		Celera
Cytogenetic Map	2	H1	NCBI
cM Map	2	78.72	NCBI

Tgm2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	167,192,612 - 167,221,845 (-)	NCBI		GRCr8
mRatBN7.2	3	146,772,684 - 146,801,924 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	146,772,687 - 146,801,981 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	150,598,013 - 150,627,250 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	159,097,613 - 159,126,553 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	156,839,077 - 156,868,039 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	154,597,165 - 154,627,257 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	154,597,168 - 154,627,257 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	160,977,905 - 161,007,261 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	148,832,866 - 148,862,385 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	148,738,777 - 148,768,294 (-)	NCBI
Celera	3	145,473,663 - 145,503,117 (-)	NCBI		Celera
Cytogenetic Map	3	q42	NCBI

Tgm2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955445	18,544,183 - 18,576,570 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955445	18,544,192 - 18,576,576 (+)	NCBI	ChiLan1.0	ChiLan1.0

TGM2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	43,851,557 - 43,889,993 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	43,844,655 - 43,881,956 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	34,450,845 - 34,488,106 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	35,561,819 - 35,599,099 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	35,561,819 - 35,599,042 (-)	Ensembl	panpan1.1		panPan2

Tgm2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	175,541,933 - 175,571,217 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936561	3,178,293 - 3,207,561 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936561	3,178,244 - 3,207,551 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TGM2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	41,186,770 - 41,221,637 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	41,186,765 - 41,221,686 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	46,592,093 - 46,629,982 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TGM2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	25,585,827 - 25,623,961 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	25,585,865 - 25,624,280 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	74,426,778 - 74,465,107 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tgm2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624842	1,491,584 - 1,522,287 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624842	1,491,583 - 1,522,293 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in TGM2
451 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_038433808	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038508959	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038572292	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038636544	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_542991	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000265	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000063	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000376	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000014092 ⟹ ENSCAFP00000013036

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	24	26,632,975 - 26,662,824 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00000059917 ⟹ ENSCAFP00000060956

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	24	26,628,009 - 26,663,840 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845051015 ⟹ ENSCAFP00845039993

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	24	27,295,164 - 27,359,267 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845051080 ⟹ ENSCAFP00845040045

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	24	27,295,164 - 27,359,067 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845051122 ⟹ ENSCAFP00845040085

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	24	27,295,164 - 27,359,067 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845051183 ⟹ ENSCAFP00845040141

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	24	27,324,530 - 27,359,068 (-)	Ensembl

RefSeq Acc Id:

XM_038433808 ⟹ XP_038289736

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	24	27,327,862 - 27,359,126 (-)	NCBI

RefSeq Acc Id:

XM_038508959 ⟹ XP_038364887

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	24	26,602,350 - 26,633,607 (-)	NCBI

RefSeq Acc Id:

XM_038572292 ⟹ XP_038428220

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	24	27,198,294 - 27,229,594 (-)	NCBI

RefSeq Acc Id:

XM_038636544 ⟹ XP_038492472

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	24	26,710,189 - 26,741,409 (-)	NCBI

RefSeq Acc Id:

XM_542991 ⟹ XP_542991

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	24	26,631,339 - 26,662,723 (-)	NCBI
Dog10K_Boxer_Tasha	24	26,277,181 - 26,308,444 (-)	NCBI

Sequence:

show sequence

GGCGGCGGCCCCGCCCCCTGCCCGCCCAACGAGGGCTATAAGTTCACATCTCTCCCAGGCTTGC
CAGTGCTCGCCCGACAGTGGTCGCACTTGCAGGGTCCAGCCACCAGGCAGAGGAGCCACCGCCA
CCACCTGACCATGGCCGAGGATCTGGTTCTCGAGAAATGTGACCTGGAGCTGGAAGCCAATGGC
CGTGACCACCACACGGCTGGCCTGTGCCAGGGGAGGCTGGTGGTGCGGCGGGGCCAGCCCTTCT
GGCTGACCCTGCACTTCACCGGCCGCAGCTATGAGTCCAGTGTGGACAGCCTCACCTTCAGCGC
CGTGACGGGCCCAGACCCCAGCGAGGAGGCCGGGACCAAGGCCCGCTTCTCCCTGTCCAGTGCT
GTGGAGGAGGGTGCCTGGACGGCCGTGGTGATGGACCAGCAGGACAGCGTCCTCTCGCTGCAGC
TCAGCACCCCGCCTAACGCCCCGGTCGGCCTGTACCGCCTCAGCCTGGAGGCCTCCACCGGCTA
CCAGGGCTCCAGCTTCGTGCTGGGCCACTTCACTCTGCTCTTCAACAGCTGGTGCCCAGCGGAT
GCTGTGTACCTGGACTCAGATGAGGAGCGGCGGGAGTACGTGCTCAGCCAGCAGGGCTTCATCT
ACCAGGGTTCAGTCAAGTTCATCAAAAGCATCCCTTGGAACTTTGGGCAGTTTGAAGATGGAAT
CCTGGACATCTGCTTGATGCTCCTGGACAGGAACCCCAAGTTCCTGAAGGATGCCTGCCGTGAC
TGCTCCAGCCGCAGCAATCCTATCTATGTGGGCCGGGTGGTGAGCGCCATGGTCAACTGCAATG
ATGACCAGGGTGTGCTGCTGGGACGCTGGGACAACAATTATAAGGACGGCATTAGCCCCATGTT
CTGGATCGGCAGCGTGGACATCCTGCGGCGCTGGAAGACCTCTGGCTGCCAGCGTGTCAAGTAT
GGCCAGTGCTGGGTCTTCGCTGCTGTGGCCTGCACAGTGCTGCGGTGCCTCGGCATCCCCACCC
GAGTGGTGACCAACTTTAACTCGGCGCATGACCAGAACAGCAACCTGCTCATCGAGTATGTCTA
CAACAAGTTTGGGGAGATCCAGAAGGAGAAAAGCGAGATGATCTGGAACTACCACTGCTGGGTG
GAGTCATGGATGAGCAGGCCGGACCTGCAGCCTGGCTATGAGGGGTGGCAGGCCCTGGACCCCA
CGCCCCAGGAGAAGAGCGAAGGGACATACTGCTGTGGCCCGGTCCCGGTGCGTGCCATCAAGGA
GGGTGATCTGAGTACCAAGTACGACGCGGCTTTTGTCTTCGCCGAGGTCAACGCCGACGTGGTG
AACTGGATCCAGCAGGACGATGGGTCCTTGTGCAAGTCCACCAACAACTCCCAGACCGTGGGGA
TGAAGATCAGCACTAAGAGCGTGGGCCGTGATGAGCGGGAGGACATCACCCACAACTACAAGTA
CCCGGAGGGGTCCCCAGAGGAGAGAGAAGCCTTCAGAAAGGCCAACCACCTGAACAAGCTGACT
GAAAAAGAGGAGACCGGGTTGGCCATGCGGATCCGCGTGAGCGAGAGCATGAGCATGGGCAGTG
ACTTTGACGTCTTTGCCTACATCAACAACAACACGTCCGAGAGCCACTCCTGCCGCCTCCTGCT
CCATGCCCGCACCGTCAGCTACAACGGGATCCTGGGGCCCGAGTGTGGCACCAAGGACCTGCTC
AATCTTTCCCTGGAGCCCTTTTCCGAGAAGAGCATCCCCCTTCGAATCCTCTATGAGAAGTACT
GTGAGTGTCTGACAGAGTCGAACCTCATCAAGGTGCGGGGCCTCCTCGTGGAACAAGCCGCCAA
CAACTACCTGCTGGCCGAGAGGGACATCTATCTGGAGAATCCAGAAATCAAGATCCGGATCCTG
GGAGAGCCCAAGCAGAACCGCAAGCTGGTGGCTGAGGCGTCCCTGCGGAACCCCCTCACCGTGC
CCCTGTTAGGCTGCAGCTTCACCATGGAAGGGGCCGGCCTCACTGAGGAGCAGAAGGTCATGGA
CGTCCCGGACCCCGTGGAGGCGGGGGAGGAGGTCAAGGTGAGAGTGGACCTGCTGCCACGCCAC
GTGGGCCGCCATAAGCTGGTGGTGAACTTTGAGAGCGACAAGCTAAAGGCTGTGAAAGGCTTCA
GGAATGTCCTCATTGGTCCCGCCTAAGGGGTGCGTGCCCAGCCCCACCTCAGCCAGCAGAGAGC
CCCTGACTTAACCCCCATTTTTGTTCCAAGCTAGTGCGCAAATGTGCCCCTTCTCGGCCTCCCC
CGACCTCAGAGCCTGTGAGGGCTCTTTGGAATGGAATGTACTTCTGGCTTATCTGGTGCCCCTG
AGCCTGGATCCCCATCTCCCTTTAACTGTGAAGAATATTCTGTGCCTCCCCAGTGGGAGCACTG
CCCTTGGCTGACTGGGTCTGCGATGGGGGAAGAGGGACCCATGCCTCCCCTTACAACCCAGAGG
CCGTTGGAAAGCCACTGACCACCCACCATATCGTTTGATTTACTCCAGAGCCCCTTGGAGCCAG
CAAAAGAGAGACAGTGTGCCCACTGACCAGATCTCAGGCAATACGCAGGCCCCAGGAACCCTTG
GGAGAACCAGAGCAGGTGCATGTGGGGTCCCAGGAAGGGCCAGACCCAAGTTCCCCTCACATCT
CAGCAGCCCTGGCCCAGCAATCCTCCCCCCCGTCAACCACCACTGTGAGGCACCTACTATGTGC
CGGGCACTTCCTGTGCTTGCTAGGGCTCACACAGCCACTGATGCACCGAAGTCACCAGGGGAGA
TCGTACAACAGGAGCTGCTTTCCCCATGAAGACCCTGGGGCTTGGAGGCGGGAGAGGCAGCCCC
TCTGCAGCAGCAGGGTATCTAAAAGGCTGGGTAGTAGGAAAGTAATTCACAGACATAAATAACT
CTGACTCCGAGTCCAGCTCCCTGTTCACGGCACTAGCCCCGACCTGAGAATATTACAGAGGCCA
TTTGGGACCTGATCAGAAAGGATGGGATGAGGTGGGGGAGGAGACCGGAGGGGTCAGGGCCCTG
GGTTTGAGCCCCAGGTCCAGCCAGCCACTGCCTTGCCCTCTCTGGCCCTTACGTCCCTCACTGG
GCAATGGAGTGGTTGACTCAGCTCATGTGCGAGGCCCTCAGCTCTGCTCTTCCAGTGCCTTAGA
GGACCCAGCCTCGCAAGTGACAGCAAGGCCAGATGCCTCTGAGTGTGAAACCCCACCTATGACC
ACCTTCCCACCCCCAGCCCTGTCTGGGTTCCCCATGTGCACCTAGGCACCTCCCTTCAGACCAC
AGTTTTAGGGAAGAGAGCTCCAGAGGCCCCTGTCCTACCCATGCACCTGCTCACTGCAATGCCT
GGACTTCACCAGAGCCTTAGTTAGCTGCCTGTGTTGGTCACTAACCAACAAGGTTAGCACCGCA
GCCACCTCCTCTCTGCAGGGCCAGGGCCCAGAAACACAGCCCTTGTCCTGACTACACTTCAAGA
GCCCATGGGCTGTCATCTCTGACTGGGTCCCCCACTCTTTCCATGTGACTGGGCTGGAAGAGGG
GTGACGGAGGGAGCATGCTCTATCCGGAGTGGGGTCACAGCCTCCAGGGCCCCCAGAATCTCAA
AGGGGCACTTGAAGAAAGTCCTGCCGATGCACGTAGAACTTTCTGCTTTGCACAGGGAAGGATC
ACAAAATAAGCCAACACGATATGTTCTTACAAATGTTGCAGTAATTATCTATGATTTGATAAAT
ACTTTTGGATTCCAAGCAGGCTTTAGAGCCACAAAGAGTGAGCACGGAAATAAAAGAGTTTGCT
TTGCACATTCAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_038289736	(Get FASTA)	NCBI Sequence Viewer
	XP_038364887	(Get FASTA)	NCBI Sequence Viewer
	XP_038428220	(Get FASTA)	NCBI Sequence Viewer
	XP_038492472	(Get FASTA)	NCBI Sequence Viewer
	XP_542991	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000013036.4
	ENSCAFP00000060956.2
	ENSCAFP00000068319.1
	ENSCAFP00000068726.1
	ENSCAFP00030041630.1
	ENSCAFP00030041657.1
	ENSCAFP00845039993.1
	ENSCAFP00845040045
	ENSCAFP00845040045.1
	ENSCAFP00845040085.1
	ENSCAFP00845040141.1

RefSeq Acc Id:

XP_542991 ⟸ XM_542991

- UniProtKB:

A0A8C0KIJ9 (UniProtKB/TrEMBL), A0A8I3PZ15 (UniProtKB/TrEMBL), A0A8P0TKR4 (UniProtKB/TrEMBL), A0A8C0PGP5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAEDLVLEKCDLELEANGRDHHTAGLCQGRLVVRRGQPFWLTLHFTGRSYESSVDSLTFSAVTG
PDPSEEAGTKARFSLSSAVEEGAWTAVVMDQQDSVLSLQLSTPPNAPVGLYRLSLEASTGYQGS
SFVLGHFTLLFNSWCPADAVYLDSDEERREYVLSQQGFIYQGSVKFIKSIPWNFGQFEDGILDI
CLMLLDRNPKFLKDACRDCSSRSNPIYVGRVVSAMVNCNDDQGVLLGRWDNNYKDGISPMFWIG
SVDILRRWKTSGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTNFNSAHDQNSNLLIEYVYNKF
GEIQKEKSEMIWNYHCWVESWMSRPDLQPGYEGWQALDPTPQEKSEGTYCCGPVPVRAIKEGDL
STKYDAAFVFAEVNADVVNWIQQDDGSLCKSTNNSQTVGMKISTKSVGRDEREDITHNYKYPEG
SPEEREAFRKANHLNKLTEKEETGLAMRIRVSESMSMGSDFDVFAYINNNTSESHSCRLLLHAR
TVSYNGILGPECGTKDLLNLSLEPFSEKSIPLRILYEKYCECLTESNLIKVRGLLVEQAANNYL
LAERDIYLENPEIKIRILGEPKQNRKLVAEASLRNPLTVPLLGCSFTMEGAGLTEEQKVMDVPD
PVEAGEEVKVRVDLLPRHVGRHKLVVNFESDKLKAVKGFRNVLIGPA

hide sequence

Ensembl Acc Id:

ENSCAFP00000060956 ⟸ ENSCAFT00000059917

Ensembl Acc Id:

ENSCAFP00000013036 ⟸ ENSCAFT00000014092

RefSeq Acc Id:

XP_038364887 ⟸ XM_038508959

RefSeq Acc Id:

XP_038492472 ⟸ XM_038636544

RefSeq Acc Id:	XP_038289736 ⟸ XM_038433808
- UniProtKB:	A0A8C0KIJ9 (UniProtKB/TrEMBL), A0A8I3PZ15 (UniProtKB/TrEMBL), A0A8P0TKR4 (UniProtKB/TrEMBL), A0A8C0PGP5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038428220 ⟸ XM_038572292
- UniProtKB:	A0A8C0KIJ9 (UniProtKB/TrEMBL), A0A8C0PGP5 (UniProtKB/TrEMBL), A0A8I3PZ15 (UniProtKB/TrEMBL), A0A8P0TKR4 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845040045 ⟸ ENSCAFT00845051080

Ensembl Acc Id:

ENSCAFP00845039993 ⟸ ENSCAFT00845051015

Ensembl Acc Id:

ENSCAFP00845040085 ⟸ ENSCAFT00845051122

Ensembl Acc Id:

ENSCAFP00845040141 ⟸ ENSCAFT00845051183

Protein Domains

Transglutaminase-like

Promoters

RGD ID:

13687604

Promoter ID:

EPDNEW_C5674

Type:

multiple initiation site

Name:

TGM2_1

Description:

transglutaminase 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	24	26,662,658 - 26,662,718	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000008869	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030025787	UniProtKB/TrEMBL
	ENSCAFG00845028869	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000014092.5	UniProtKB/TrEMBL
	ENSCAFT00000059917.2	UniProtKB/TrEMBL
	ENSCAFT00000103962.1	UniProtKB/TrEMBL
	ENSCAFT00000105718.1	UniProtKB/TrEMBL
	ENSCAFT00030047608.1	UniProtKB/TrEMBL
	ENSCAFT00030047638.1	UniProtKB/TrEMBL
	ENSCAFT00845051015.1	UniProtKB/TrEMBL
	ENSCAFT00845051080	ENTREZGENE
	ENSCAFT00845051080.1	UniProtKB/TrEMBL
	ENSCAFT00845051122.1	UniProtKB/TrEMBL
	ENSCAFT00845051183.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
	3.90.260.10	UniProtKB/TrEMBL
InterPro	Ig-like_fold	UniProtKB/TrEMBL
	Ig_E-set	UniProtKB/TrEMBL
	Papain-like_cys_pep_sf	UniProtKB/TrEMBL
	Transglutaminase	UniProtKB/TrEMBL
	Transglutaminase-like	UniProtKB/TrEMBL
	Transglutaminase-like_sf	UniProtKB/TrEMBL
	Transglutaminase_animal	UniProtKB/TrEMBL
	Transglutaminase_AS	UniProtKB/TrEMBL
	Transglutaminase_C	UniProtKB/TrEMBL
	Transglutaminase_C_sf	UniProtKB/TrEMBL
	Transglutaminase_N	UniProtKB/TrEMBL
KEGG Report	cfa:485867	UniProtKB/TrEMBL
NCBI Gene	TGM2	ENTREZGENE
PANTHER	PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE	UniProtKB/TrEMBL
	PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE 2	UniProtKB/TrEMBL
Pfam	Transglut_C	UniProtKB/TrEMBL
	Transglut_core	UniProtKB/TrEMBL
	Transglut_N	UniProtKB/TrEMBL
PIRSF	TGM_EBP42	UniProtKB/TrEMBL
PROSITE	TRANSGLUTAMINASES	UniProtKB/TrEMBL
SMART	TGc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF49309	UniProtKB/TrEMBL
	SSF54001	UniProtKB/TrEMBL
	SSF81296	UniProtKB/TrEMBL
UniProt	A0A8C0KIJ9	ENTREZGENE
	A0A8C0PGP5	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0RTX1_CANLF	UniProtKB/TrEMBL
	A0A8I3PZ15	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3Q1N6_CANLF	UniProtKB/TrEMBL
	A0A8I3Q5I7_CANLF	UniProtKB/TrEMBL
	A0A8I3SBW6_CANLF	UniProtKB/TrEMBL
	A0A8P0SE26_CANLF	UniProtKB/TrEMBL
	A0A8P0TK64_CANLF	UniProtKB/TrEMBL
	A0A8P0TKR4	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	A0A8P0P9X0	UniProtKB/TrEMBL
VGNC ID	VGNC:47316	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - MGI

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

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Imported Annotations - PID (archival)