Advanced Search (OLGA)

Gene: LOC490269 (complement receptor type 2) Canis lupus familiaris

Subscribe to Updates

Analyze

Symbol:

LOC490269 (Ensembl: CR1L)

Name:

complement receptor type 2

RGD ID:

12250166

Description:

ENCODES a protein that exhibits complement component C3b binding (ortholog); complement component C3b receptor activity (ortholog); complement component C4b binding (ortholog); INVOLVED IN ATP export (ortholog); complement activation, alternative pathway (ortholog); complement receptor mediated signaling pathway (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); autistic disorder (ortholog); Cognitive Dysfunction (ortholog); FOUND IN cell surface (ortholog); cytoskeleton (ortholog); plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

complement C3b/C4b receptor 1 like; complement C3d receptor 2; complement component (3b/4b) receptor 1 (Knops blood group); complement component receptor 2; complement receptor type 1; complement receptor type 1-like; CR1; CR1L; CR2; LOC102157092

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	6,456,238 - 6,480,672 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	6,010,653 - 6,111,952 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	6,136,180 - 6,237,734 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	6,172,539 - 6,221,909 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	6,069,432 - 6,170,965 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	6,171,726 - 6,273,128 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	6,212,125 - 6,314,023 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
LOC490269	Dog	autistic disorder		ISO	RGD:1603411	8554872	ClinVar Annotator: match by term: Autism	ClinVar	PMID:21681106\|PMID:30208311
LOC490269	Dog	common variable immunodeficiency 7		ISO	RGD:1603411	8554872	ClinVar Annotator: match by term: Immunodeficiency, common variable, 7	ClinVar	PMID:28492532
LOC490269	Dog	gastrointestinal stromal tumor		ISO	RGD:1603411	8554872	ClinVar Annotator: match by term: Gastrointestinal stromal tumor	ClinVar	PMID:28492532
LOC490269	Dog	Hypokalemic Periodic Paralysis, Type 1		ISO	RGD:1603411	8554872	ClinVar Annotator: match by term: Hypokalemic periodic paralysis, type 1	ClinVar	PMID:28492532
LOC490269	Dog	hypothyroidism		ISO	RGD:1603411	8554872	ClinVar Annotator: match by term: Hypothyroidism	ClinVar	PMID:25741868
LOC490269	Dog	inflammatory bowel disease		ISO	RGD:1603411	8554872	ClinVar Annotator: match by term: Inflammatory bowel disease	ClinVar	PMID:28492532
LOC490269	Dog	malaria		ISO	RGD:1603411	8554872	ClinVar Annotator: match by term: CR1-related condition \| ClinVar Annotator: match by term: Malaria, severe, more ...	ClinVar	PMID:10528197\|PMID:14694201\|PMID:20855594\|PMID:25741868
LOC490269	Dog	parathyroid carcinoma		ISO	RGD:1603411	8554872	ClinVar Annotator: match by term: Parathyroid carcinoma	ClinVar	PMID:28492532

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
LOC490269	Dog	Alzheimer's disease		ISO	RGD:1603411	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:19734903\|PMID:21460841
LOC490269	Dog	Cognitive Dysfunction		ISO	RGD:1603411	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:30503753
LOC490269	Dog	Plasmodium falciparum malaria		ISO	RGD:1603411	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:11724985\|PMID:9230440

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
LOC490269	Dog	malaria		ISO	RGD:1603411	7240710		OMIM

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
LOC490269	Dog	ATP export	acts_upstream_of_or_within	ISO	RGD:1603411	9068941	PMID:24022490	ARUK-UCL	PMID:24022490
LOC490269	Dog	complement activation, alternative pathway	involved_in	ISO	RGD:1603411	9068941	PMID:11981823	ARUK-UCL	PMID:11981823
LOC490269	Dog	complement receptor mediated signaling pathway	involved_in	ISO	RGD:1603411	9068941	PMID:16360013, PMID:22962438	ARUK-UCL	PMID:16360013\|PMID:22962438
LOC490269	Dog	immune complex clearance by erythrocytes	involved_in	ISO	RGD:1603411	9068941	PMID:24022490	ARUK-UCL	PMID:24022490
LOC490269	Dog	negative regulation of activation of membrane attack complex	acts_upstream_of	ISO	RGD:1603411	9068941	PMID:31862673	ARUK-UCL	PMID:31862673
LOC490269	Dog	negative regulation of complement activation	involved_in	ISO	RGD:1603411	9068941	PMID:31862673	ARUK-UCL	PMID:31862673
LOC490269	Dog	negative regulation of complement activation, alternative pathway	involved_in	ISO	RGD:1603411	9068941	PMID:10531307	UniProt	PMID:10531307
LOC490269	Dog	negative regulation of complement activation, classical pathway	involved_in	IBA	PANTHER:PTN008569518\|UniProtKB:O02839\|UniProtKB:P04003\|UniProtKB:P17927	150520179		GO_Central	GO_REF:0000033
LOC490269	Dog	negative regulation of complement-dependent cytotoxicity	involved_in	ISO	RGD:1603411	9068941	PMID:31862673	ARUK-UCL	PMID:31862673
LOC490269	Dog	negative regulation of immunoglobulin production	acts_upstream_of	ISO	RGD:1603411	9068941	PMID:22962438	ARUK-UCL	PMID:22962438
LOC490269	Dog	negative regulation of interleukin-2 production	acts_upstream_of_or_within	ISO	RGD:1603411	9068941	PMID:16360013	ARUK-UCL	PMID:16360013
LOC490269	Dog	negative regulation of plasma cell differentiation	acts_upstream_of	ISO	RGD:1603411	9068941	PMID:22962438	ARUK-UCL	PMID:22962438
LOC490269	Dog	negative regulation of serine-type endopeptidase activity	involved_in	ISO	RGD:1603411	9068941	PMID:6910481	UniProt	PMID:6910481
LOC490269	Dog	negative regulation of T cell proliferation	involved_in	ISO	RGD:1603411	9068941	PMID:16360013	ARUK-UCL	PMID:16360013
LOC490269	Dog	negative regulation of type II interferon production	acts_upstream_of_or_within	ISO	RGD:1603411	9068941	PMID:16360013	ARUK-UCL	PMID:16360013
LOC490269	Dog	plasma membrane organization	involved_in	ISO	RGD:1603411	9068941	PMID:24022490	ARUK-UCL	PMID:24022490
LOC490269	Dog	positive regulation of activation of membrane attack complex	involved_in	ISO	RGD:1603411	9068941	PMID:11981823	ARUK-UCL	PMID:11981823
LOC490269	Dog	positive regulation of cell population proliferation	involved_in	ISO	RGD:1603411	9068941	PMID:25742728	ARUK-UCL	PMID:25742728
LOC490269	Dog	positive regulation of regulatory T cell differentiation	involved_in	ISO	RGD:1603411	9068941	PMID:25742728	ARUK-UCL	PMID:25742728
LOC490269	Dog	positive regulation of serine-type endopeptidase activity	involved_in	ISO	RGD:1603411	9068941	PMID:2972794	UniProt	PMID:2972794
LOC490269	Dog	T cell mediated immunity	involved_in	IBA	PANTHER:PTN000448838\|UniProtKB:P15529	150520179		GO_Central	GO_REF:0000033

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
LOC490269	Dog	cell surface	located_in	ISO	RGD:1603411	9068941	PMID:25742728, PMID:2972794, PMID:6978375	ARUK-UCL	PMID:25742728\|PMID:2972794\|PMID:6978375
LOC490269	Dog	cytoskeleton	located_in	ISO	RGD:1603411	9068941	PMID:18684861	ARUK-UCL	PMID:18684861
LOC490269	Dog	extracellular space	is_active_in	IBA	PANTHER:PTN008569518\|RGD:1310065\|UniProtKB:P04003	150520179		GO_Central	GO_REF:0000033
LOC490269	Dog	membrane	located_in	IEA	UniProtKB-KW:KW-0472	150520179		UniProt	GO_REF:0000043
LOC490269	Dog	plasma membrane	located_in	ISO	RGD:1603411	9068941	PMID:6910481	UniProt	PMID:6910481
LOC490269	Dog	plasma membrane	is_active_in	IBA	MGI:104965\|MGI:88489\|MGI:88513\|PANTHER:PTN000448838\|RGD:3061\|UniProtKB:P15529\|UniProtKB:P17927\|UniProtKB:P20023	150520179		GO_Central	GO_REF:0000033
LOC490269	Dog	plasma membrane raft	located_in	ISO	RGD:1603411	9068941	PMID:24022490	ARUK-UCL	PMID:24022490

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
LOC490269	Dog	complement component C3b binding	enables	ISO	RGD:1603411	9068941	PMID:2972794	UniProt	PMID:2972794
LOC490269	Dog	complement component C3b receptor activity	enables	ISO	RGD:1603411	9068941	PMID:2972794	UniProt	PMID:2972794
LOC490269	Dog	complement component C4b binding	enables	ISO	RGD:1603411	9068941	PMID:2972794	UniProt	PMID:2972794
LOC490269	Dog	complement component C4b receptor activity	enables	ISO	RGD:1603411	9068941	PMID:2972794	UniProt	PMID:2972794
LOC490269	Dog	protein binding	enables	ISO	UniProtKB:Q12923	9068941	PMID:18684861	ARUK-UCL	PMID:18684861
LOC490269	Dog	protein binding	enables	ISO	UniProtKB:O75636\|UniProtKB:P11226\|UniProtKB:Q15485	9068941	PMID:23460739	IntAct	PMID:23460739
LOC490269	Dog	protein binding	enables	ISO	UniProtKB:P11226	9068941	PMID:29563915	IntAct	PMID:29563915

LOC490269
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	6,456,238 - 6,480,672 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	6,010,653 - 6,111,952 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	6,136,180 - 6,237,734 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	6,172,539 - 6,221,909 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	6,069,432 - 6,170,965 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	6,171,726 - 6,273,128 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	6,212,125 - 6,314,023 (+)	NCBI		UU_Cfam_GSD_1.0

CR1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	207,496,157 - 207,641,765 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	207,496,147 - 207,641,765 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	207,669,502 - 207,815,110 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	205,736,096 - 205,881,733 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	180,918,501 - 181,045,588 (+)	NCBI		Celera
Cytogenetic Map	1	q32.2	NCBI
HuRef	1	178,362,547 - 178,489,425 (+)	NCBI		HuRef
CHM1_1	1	208,942,210 - 209,087,469 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	206,761,475 - 206,888,507 (+)	NCBI		T2T-CHM13v2.0

CR2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	41,889,483 - 41,926,416 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	41,855,514 - 41,892,457 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	183,052,798 - 183,088,385 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	187,330,483 - 187,366,069 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	187,330,483 - 187,366,069 (+)	Ensembl	panpan1.1		panPan2

LOC101964865
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	67,939,369 - 68,000,505 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936557	5,185,831 - 5,284,999 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CR1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	9	68,025,673 - 68,132,162 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	74,459,456 - 74,562,534 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CR2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	21,914,690 - 21,954,244 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	21,919,393 - 21,953,659 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	22,536,015 - 22,575,130 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants in LOC490269
252 total Variants

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	XM_005622317	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005622319	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022420855	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038480700	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038542030	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038561911	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038561920	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038561925	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038561932	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038561950	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038606160	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038606161	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038606162	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038606163	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038606164	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038606165	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038606166	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038670858	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038670859	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038670860	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038670861	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038670862	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038670863	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005372681	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005396360	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005429564	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB196669	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000080	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000093	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00845004051 ⟹ ENSCAFP00845003240

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	7	6,172,539 - 6,221,566 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845004091 ⟹ ENSCAFP00845003275

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	7	6,186,631 - 6,207,769 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845004111 ⟹ ENSCAFP00845003291

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	7	6,186,669 - 6,211,082 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845004121 ⟹ ENSCAFP00845003298

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	7	6,186,917 - 6,203,309 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845004129 ⟹ ENSCAFP00845003304

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	7	6,208,132 - 6,221,909 (+)	Ensembl

RefSeq Acc Id:

XM_005622317 ⟹ XP_005622374

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	7	6,046,612 - 6,111,952 (+)	NCBI

Sequence:

show sequence

GCAGCGCTGCCCAGACCGCGGGCGCAGGGCGCGCTCTGGGCTCTCGGCGGGGCGGCCGGTGCTGCCCTTGAGGTCGCGCCTGCACCGGCAGGTGCCCGCGGAGGACGGGAGCCCCGCGGAGGACGGGA
GCCCCGCGGAGGATGGGAGCCCCGCAGAGGGCGGGAGCCCCGCGGAGGATGGGAGCCCCGCAGAGGGCGGGAGCCCCGCGGAGCACGGGAGCCCCGCGGAGCAGGAGCCCGCAGGAGGCCCCGCGGTC
CCGCCCGGGAGGAGCTCTCCCCGCGTTCCTGGTGCTGCTCGCGCTGCCCGAGGCCTGGGGTCAATGCAAAGCCCCAGAACAGCTTCCATTTGCCAAGCCTTTAAGACTGTTCAATGAGTCTGAGTTTC
CCATTGGGACATCTATTAAGTATGAGTGCCGCCCTGGTTACCAAAAGAGAGTGTTCTCCATGAAGTGCCTACAGAACTCGGTCTGGTCAAGCATTGAAAATATGTGTAAACGTAAATCATGTGGAACT
CCTCCAGAACTCCTGAATGGCAAATTGACGGTAGACGGAGACGCCCGGTTTGGATCAACTGTTCATTATGCTTGTAATGTAGGATACCAACTTATTGGTCATTCCTCTATTTCATGCATCATCTCAGA
TAATACTGTCGTCTGGGATGATGATCCACCTATTTGTGAGACTATTCATTGTGAGCCACCCCCGGACATTGCCAATGGAGATTTCCTTAGCACCAACAGAGAATATTTTCCATATGCAACCGTGGTGA
CCTATCGCTGCAATACTGGACATAGAGGGGAAAAGCTGTATGAGCTTGTGGGCAACCCATCAATATATTGTACCAGCGAAGACAATCGAGTTGGCACGTGGAGCGACCTTCCCCCTCAGTGCATTGTA
CTTAATAGATGCACACCTCCAGACATTGAAAATGCTATAAGGATATCTGAGAACAAAAGTTTATTTTTCTTATATGAAACCGTGAGGTTTATCTGTAAGCCTGGCTTTGTCATGGAAGGACCCTCCAA
CGTGTATTGCCAACGCCAAAACAAATGGGGGCCGGAGTTGCCAAGCTGCACTAGGGCATGTCAGGCACCTCCAGAAATTTTCCACGGTAAGCACAGCGCAAGGAACAAGGACAGTTTTGCCCCCGGAC
AGGAAGTGTTCTACAGCTGTGAGCCTGGCTATGAGCTCCAAGGGGCTGCTTCTCTGCGCTGTACACCCCAGGGAGACTGGAGCCCAGCAGCCCCAAGATGTGAAGGGAAATCATGTGCTGACTTCCTG
GACCAACTCCCTAATGGTCATGTGCTCTTTCCAATTAGTCTTCAACTTGGGGCAAAAGTGTCCTTCGTGTGTGATGAGGGGTTCCGCTTACAGGGGAGTTCTGCTAGTTACTGTGTCTTGGTTGGAAC
GGAAAGCCTTTGGAATAACAGTGTTCCTGTGTGTGAACAAATCTTCTGTCCAAATCCTCCATCTATCCTTAACGGGCACCACACTGGAACTTCTTGGGGACGCATTCCCTATGGAAAAGAAATTACTT
ACACGTGTGACCACCACCCAACCAGAGGGATGATCTTCAAACTCATTGGGGAGAGCACAATCTTCTGCACCAGTGACAATCAAGGGAATGGGATTTGGAGCGGCCCTGCCCCTCACTGTGTACTTGCT
GGTCCTGCTGGTTACTGTAAAGCTCCAGAGGAGTTTCCGTTTGCCAAACCTTTGACCGCGATCAATGAGTCTGAGTTTCCAATTGGGACGTCTTTGAATTATAAATGTCTGCCTGGGTATTCTGAGAA
TACGTTTTCTATCACCTGTTTAGAAAACTTGGTCTGGTCGAGTGCCAAAGATATCTGTAGACGAAAATCATGTGGAACTCCCCCAGAACCCATCAATGGCATGGTGCAAATAATCACAGATACTCAAT
TTGGATCAACAGTTCATTACTCTTGTAATGAAGGGTATCGACTCATTGGCTCCCCTTCCGCTGCGTGTCTCCTCTTGGGCAGTACTGTCACTTGGGATAAGGAAGCACCTATGTGTGAAAAAATCTTT
TGTCCAAATCCTCCATCTATCCCTAACGGGCACCACACTGGAACTTCTTGGGGACGCATTCCCTATGGAAAAGAAATTACTTACATTTGTGACTACCAGCCAGCCAGCGGGATGATCTTCAAACTCGT
TGGGGAGAGCACCATCCTCTGCACCAGTGACAATCAAGGGAACGGGATTTGGAGCGGCCCTGCTCCTCACTGTGAACCTGCTGGTCCTACAGCATGCCCATATCCACCCAAGATCCACAACGGGCATT
ACATTGGAAGACATGTGTCTCCATATCTTCCTGGGATGATCGTCAGCTATGCTTGTGATCCAGGCTACTTGTTGGTGGGAAGAGCCTTCATATTCTGCACCTACCAGGGAACCTGGAGCCAATTTGAT
CATTATTGCAAAGAGATAAAATGTATCCTCCCAGAGTTTATGAATGGAATCCAGAAGAAGTTGCACATGAGAAAAGTATACCACTATGGAGATAATGTAACTTTTGAGTGTGAAGTTGGATATACTCT
AAAAGGCAGTCGCCAGAGTCAGTGTCAGGCAGATGACACATGGAACCCTCCTCTGGCCGTATGTACATCGAGCACACGGGATGCTCTCACAACTGGCCTTGTCTTTGGTGTGATCTTTCTCTTACTCA
TCATTGTTTCCTGTTGCATAATTATAAAGCACAGAAAACGCACCAATACAGATGAAAAACCTAAAGAGAATATCCATTTAAGTCCTCAAGAAGACAGCGGCATACAGCCTCAAACTCTGCAAACAAAT
CAGGAAAACAGCAGTGCCCTTCCCTGAGAAAGTACTCTCACGCTGGAGAACATCTTGAATTAAAATGTTGTTGGAAAGGAGCTAATTCAACAGAGGAAGATGTGAAACTCGTAACTTCTTGGAAGTGA
CCTCACAGAGATACAAACATGTGCACCTGAAGATGCTGAAGTGCTCCCAGGAGCTGGTAAAGGCTCCCCTCCTCTCAGCTTGGATACTGTCACTCCATGTGCTCTTTCCTTGTGCGGGAAGCACACGT
CATCTAGTTAGGGGAAAAGTCTGCACCAAGGCTATATAGACTCAATCACTTAAAAGAAGAAGGTGTCACTTAGGATTTCTGTTTACAAGTCTGTTCATCACCTTTCTTATTTTCAAATGCTCATGCTA
TAAAATGGGCTCGTAACAAGAATATCAAAATCCAGGATGAAGATATGAAAAACAAATAAGTCACGTACAATACTACTCAGTGATAACTGCTGTCAATATTTGATTCATTTTCTGCTAACCTTTCTTCA
TAGATGTTTATTTTTTTATACACAGGTCTTTCTTACTTTTTCTGTAGAGCAAAATCTCCTATTAGATCAGAGTAAAATCTAGCTAGATCAGTTTTTATGTTCTTTAGGGAAAGAAGTATTTTCTGTTG
ATTACAAAGGCAGTATGGGCAGCCTCGGTGGCTCAGCGGTGTAGTGCCGCCTTTAGCACAGGGTCTGATCCTGGAGACCTGGGATCCAACCCGCGTCGGGCTCCCTGCATGGAACCTGCTTATATCTC
TGCCTCTCTCTCACTGTCTCTCATGAATGAATAAATAAAATCTTAAAAAAAAAAAAAAAGGCATTAAGTGAATCTGGGAGAGAGGTTTTCAGGAGAAACATTTTAAACAATGAGCTTTGGATATTTCC
TAAGCTCTATTTCAAAATCAATTTGAACTATGTTCCATATAAAAAATACTATTTTAAATAAAAGAAGTTTCATTATAAAAGGAAGGGACTTAGTTGTGTGTAGACTCAGAACACATCAATAAATTAAG
AAACCATGACTTTTAAGAATTGCAAAATTAACATACAAGTAAGTATAGAACTAAGTGGCCCTGGATTCCCACACTGGTTCACATACTTACAGATCAAAAATTTATTTAGTATGATATCATGGGTCGTG
CTAATGATCTAGAGAATATCAGAGCCCTTCTGGATATTTAACAATAGGTTTGCATATGACTACTGCTAACCACTGTACAATTTGGGTTTAGGTGGCTTTTAGAGTCTAGTCTGTCACACTTACCTTGA
AAACATACAGAATGAACTGCACATCAACTTGAAGTTTTCTTTAAAATCAGGAAGATAGAAAAAAACAGGAGCAGCAAAGTCAACTGACAAACTAGGAGGAAAAAATTACAACTTGTATCACAGACAAG
CATAACTGGCATATTTGGAGAGTTAAAAGTTTAAAGGCCAACCCTCCCCACCCTACTTGCCTTAAATAGACAAAGGACATACCGCCAAGCCACCAAGAGAGAGGCAGGTCACCCATGAATATATGAAA
AGATTCTCAATGGTTTTGCTTGTTGAAACTTAGGGAAATCTAGTAGGTCTTGAGTGTCTGAAGAAGTACACTTTAAAGGAGGGCTAGAAATTAACTGCTGGCAATTGGACTTTCTTAGAATTAAAATT
CCCTATCACAAGAAAAAAATATAGGTTCCTCTTTCTTCCCAGAATGCAGTAGGTCAGTGAGTACTGTGATTAACTGGTATCTGATGCCTGGGAATTGAATTTAAAGAAATTCATGAGATTCTTTGGTC
TGTGACATCAGTGATACATGGGAACTGCTGTATATACTAACACAGGCAAAATACTGAATTGCCTACTTTCATTTGTGTCGCTGAGCAATTCTGTTAGCCTCTGGCCTTCCATTTTTCATCTGAACGTA
GGGCTGGACCAACTAGTCTCCAAAGCTATTATTACTGCTAACAATCTAACTTTTCTTCTGGTTTCCTTTTTGTATACTTTACACGTAAGTGTGACGTAATTTCAAGTCTATGCCGTTTAAATAAAATG
TTCTGTGTCCACTTGTATAACAGGGAAGGAATAAAAGATTTTTTTTCTTTCTAAATCTA

hide sequence

RefSeq Acc Id:

XM_038480700 ⟹ XP_038336628

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	7	6,069,432 - 6,170,965 (+)	NCBI

RefSeq Acc Id:

XM_038542030 ⟹ XP_038397958

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	7	6,212,125 - 6,314,023 (+)	NCBI

RefSeq Acc Id:

XM_038561911 ⟹ XP_038417839

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	7	6,010,659 - 6,042,963 (+)	NCBI

RefSeq Acc Id:

XM_038561920 ⟹ XP_038417848

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	7	6,010,659 - 6,042,963 (+)	NCBI

RefSeq Acc Id:

XM_038561925 ⟹ XP_038417853

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	7	6,010,675 - 6,042,963 (+)	NCBI

RefSeq Acc Id:

XM_038561932 ⟹ XP_038417860

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	7	6,010,653 - 6,042,963 (+)	NCBI

RefSeq Acc Id:

XM_038561950 ⟹ XP_038417878

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	7	6,010,659 - 6,111,952 (+)	NCBI

RefSeq Acc Id:

XM_038606160 ⟹ XP_038462088

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	7	6,171,732 - 6,204,042 (+)	NCBI

RefSeq Acc Id:

XM_038606161 ⟹ XP_038462089

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	7	6,171,732 - 6,204,042 (+)	NCBI

RefSeq Acc Id:

XM_038606162 ⟹ XP_038462090

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	7	6,171,748 - 6,204,042 (+)	NCBI

RefSeq Acc Id:

XM_038606163 ⟹ XP_038462091

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	7	6,171,726 - 6,204,042 (+)	NCBI

RefSeq Acc Id:

XM_038606164 ⟹ XP_038462092

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	7	6,207,703 - 6,268,098 (+)	NCBI

RefSeq Acc Id:

XM_038606165 ⟹ XP_038462093

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	7	6,207,704 - 6,273,128 (+)	NCBI

RefSeq Acc Id:

XM_038606166 ⟹ XP_038462094

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	7	6,171,732 - 6,268,098 (+)	NCBI

RefSeq Acc Id:

XM_038670858 ⟹ XP_038526786

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	7	6,136,186 - 6,168,488 (+)	NCBI

RefSeq Acc Id:

XM_038670859 ⟹ XP_038526787

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	7	6,136,186 - 6,168,488 (+)	NCBI

RefSeq Acc Id:

XM_038670860 ⟹ XP_038526788

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	7	6,136,202 - 6,168,488 (+)	NCBI

RefSeq Acc Id:

XM_038670861 ⟹ XP_038526789

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	7	6,136,180 - 6,168,488 (+)	NCBI

RefSeq Acc Id:

XM_038670862 ⟹ XP_038526790

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	7	6,172,391 - 6,237,734 (+)	NCBI

RefSeq Acc Id:

XM_038670863 ⟹ XP_038526791

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	7	6,136,186 - 6,237,734 (+)	NCBI

RefSeq Acc Id:

XR_005372681

Type:

NON-CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	7	6,046,609 - 6,111,952 (+)	NCBI

RefSeq Acc Id:

XR_005396360

Type:

NON-CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	7	6,207,703 - 6,273,128 (+)	NCBI

RefSeq Acc Id:

XR_005429564

Type:

NON-CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	7	6,172,388 - 6,237,734 (+)	NCBI


Protein RefSeqs	XP_005622374	(Get FASTA)	NCBI Sequence Viewer
	XP_038336628	(Get FASTA)	NCBI Sequence Viewer
	XP_038397958	(Get FASTA)	NCBI Sequence Viewer
	XP_038417839	(Get FASTA)	NCBI Sequence Viewer
	XP_038417848	(Get FASTA)	NCBI Sequence Viewer
	XP_038417853	(Get FASTA)	NCBI Sequence Viewer
	XP_038417860	(Get FASTA)	NCBI Sequence Viewer
	XP_038417878	(Get FASTA)	NCBI Sequence Viewer
	XP_038462088	(Get FASTA)	NCBI Sequence Viewer
	XP_038462089	(Get FASTA)	NCBI Sequence Viewer
	XP_038462090	(Get FASTA)	NCBI Sequence Viewer
	XP_038462091	(Get FASTA)	NCBI Sequence Viewer
	XP_038462092	(Get FASTA)	NCBI Sequence Viewer
	XP_038462093	(Get FASTA)	NCBI Sequence Viewer
	XP_038462094	(Get FASTA)	NCBI Sequence Viewer
	XP_038526786	(Get FASTA)	NCBI Sequence Viewer
	XP_038526787	(Get FASTA)	NCBI Sequence Viewer
	XP_038526788	(Get FASTA)	NCBI Sequence Viewer
	XP_038526789	(Get FASTA)	NCBI Sequence Viewer
	XP_038526790	(Get FASTA)	NCBI Sequence Viewer
	XP_038526791	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAD81024	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000017158.5
	ENSCAFP00000041299.2
	ENSCAFP00000043609.1
	ENSCAFP00000044302.1
	ENSCAFP00000052589.1
	ENSCAFP00000059435.1
	ENSCAFP00000070043.1
	ENSCAFP00000072556.1
	ENSCAFP00000072677.1
	ENSCAFP00000072848.1
	ENSCAFP00000073850.1
	ENSCAFP00040024999.1
	ENSCAFP00845002880
	ENSCAFP00845002880.1
	ENSCAFP00845002941
	ENSCAFP00845002941.1
	ENSCAFP00845002977
	ENSCAFP00845002977.1
	ENSCAFP00845003027
	ENSCAFP00845003027.1
	ENSCAFP00845003083.1
	ENSCAFP00845003114.1
	ENSCAFP00845003240.1
	ENSCAFP00845003275.1
	ENSCAFP00845003291.1
	ENSCAFP00845003298.1
	ENSCAFP00845003304.1

RefSeq Acc Id:	XP_038336628 ⟸ XM_038480700
- Peptide Label:	isoform X7

RefSeq Acc Id:	XP_038462091 ⟸ XM_038606163
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_038462094 ⟸ XM_038606166
- Peptide Label:	isoform X9

RefSeq Acc Id:	XP_038462088 ⟸ XM_038606160
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038462089 ⟸ XM_038606161
- Peptide Label:	isoform X3

Protein Domains

Sushi

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000011630	UniProtKB/TrEMBL
	ENSCAFG00000046356	UniProtKB/TrEMBL
	ENSCAFG00040015457	UniProtKB/TrEMBL
	ENSCAFG00845002088	ENTREZGENE, UniProtKB/TrEMBL
	ENSCAFG00845002283	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000018525.6	UniProtKB/TrEMBL
	ENSCAFT00000048008.3	UniProtKB/TrEMBL
	ENSCAFT00000062431.2	UniProtKB/TrEMBL
	ENSCAFT00000081251.2	UniProtKB/TrEMBL
	ENSCAFT00000082866.2	UniProtKB/TrEMBL
	ENSCAFT00000091624.2	UniProtKB/TrEMBL
	ENSCAFT00000098412.1	UniProtKB/TrEMBL
	ENSCAFT00000099151.1	UniProtKB/TrEMBL
	ENSCAFT00000107199.1	UniProtKB/TrEMBL
	ENSCAFT00000109289.1	UniProtKB/TrEMBL
	ENSCAFT00000109980.1	UniProtKB/TrEMBL
	ENSCAFT00040028784.1	UniProtKB/TrEMBL
	ENSCAFT00845003628	ENTREZGENE
	ENSCAFT00845003628.1	UniProtKB/TrEMBL
	ENSCAFT00845003699	ENTREZGENE
	ENSCAFT00845003699.1	UniProtKB/TrEMBL
	ENSCAFT00845003748	ENTREZGENE
	ENSCAFT00845003748.1	UniProtKB/TrEMBL
	ENSCAFT00845003804	ENTREZGENE
	ENSCAFT00845003804.1	UniProtKB/TrEMBL
	ENSCAFT00845003869.1	UniProtKB/TrEMBL
	ENSCAFT00845003905.1	UniProtKB/TrEMBL
	ENSCAFT00845004051.1	UniProtKB/TrEMBL
	ENSCAFT00845004091.1	UniProtKB/TrEMBL
	ENSCAFT00845004111.1	UniProtKB/TrEMBL
	ENSCAFT00845004121.1	UniProtKB/TrEMBL
	ENSCAFT00845004129.1	UniProtKB/TrEMBL
Gene3D-CATH	Complement Module, domain 1	UniProtKB/TrEMBL
InterPro	Compl-Cell_Adhes-Reg	UniProtKB/TrEMBL
	SEZ6_CSMD_C4BPB_Regulators	UniProtKB/TrEMBL
	Sushi/SCR/CCP_sf	UniProtKB/TrEMBL
	Sushi_SCR_CCP_dom	UniProtKB/TrEMBL
NCBI Gene	CR2	ENTREZGENE
PANTHER	COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING	UniProtKB/TrEMBL
	COMPLEMENT RECEPTOR TYPE 1	UniProtKB/TrEMBL
	CUB AND SUSHI DOMAIN-CONTAINING PROTEIN 1	UniProtKB/TrEMBL
	PROTEIN CBR-CLEC-78	UniProtKB/TrEMBL
	PROTEIN CBR-CLEC-78	UniProtKB/TrEMBL
	SUSHI DOMAIN-CONTAINING PROTEIN	UniProtKB/TrEMBL
Pfam	Sushi	UniProtKB/TrEMBL
PROSITE	SUSHI	UniProtKB/TrEMBL
SMART	CCP	UniProtKB/TrEMBL
Superfamily-SCOP	SSF57535	UniProtKB/TrEMBL
UniProt	A0A8C0SQU3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3MF80	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3MF96	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3MIN5_CANLF	UniProtKB/TrEMBL
	A0A8I3MKC2_CANLF	UniProtKB/TrEMBL
	A0A8I3MKM4_CANLF	UniProtKB/TrEMBL
	A0A8I3MKY0_CANLF	UniProtKB/TrEMBL
	A0A8I3MLF7_CANLF	UniProtKB/TrEMBL
	A0A8I3MM07	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3N180	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3N1T1_CANLF	UniProtKB/TrEMBL
	A0A8I3RS25	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0NUM8_CANLF	UniProtKB/TrEMBL
	A0A8P0P2A7_CANLF	UniProtKB/TrEMBL
	A0A8P0P8H7_CANLF	UniProtKB/TrEMBL
	A0A8P0PN91_CANLF	UniProtKB/TrEMBL
	A0A8P0PPL1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0SGD6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0SV26_CANLF	UniProtKB/TrEMBL
	A0A8P0SX06_CANLF	UniProtKB/TrEMBL
	A0A8P0TMI8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0TR56	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0TRK6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-01-14	LOC490269	complement receptor type 2	CR1L	complement C3b/C4b receptor 1 like	Data merged from RGD:12403495	737654	PROVISIONAL
2021-01-12	LOC490269	complement receptor type 2	CR2	complement C3d receptor 2	Symbol and/or name change	5135510	APPROVED
2017-09-12	CR1L	complement C3b/C4b receptor 1 like	LOC102157092	complement receptor type 1-like	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
		Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM