MIR488 (microRNA mir-488) - Rat Genome Database

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Gene: MIR488 (microRNA mir-488) Canis lupus familiaris
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Symbol: MIR488
Name: microRNA mir-488 (Ensembl:microRNA 488)
RGD ID: 12248998
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: cfa-mir-488; microRNA 488
RGD Orthologs
Human
Mouse
Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1722,597,953 - 22,598,035 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl722,597,953 - 22,598,035 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha722,122,143 - 22,122,225 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0722,344,624 - 22,344,706 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl722,344,624 - 22,344,706 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1722,250,245 - 22,250,327 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0722,350,320 - 22,350,402 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0722,493,251 - 22,493,333 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
RISC complex  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:16381832   PMID:18215311  


Genomics

Comparative Map Data
MIR488
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1722,597,953 - 22,598,035 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl722,597,953 - 22,598,035 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha722,122,143 - 22,122,225 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0722,344,624 - 22,344,706 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl722,344,624 - 22,344,706 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1722,250,245 - 22,250,327 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0722,350,320 - 22,350,402 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0722,493,251 - 22,493,333 (+)NCBIUU_Cfam_GSD_1.0
MIR488
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381177,029,363 - 177,029,445 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1177,029,363 - 177,029,445 (-)EnsemblGRCh38hg38GRCh38
GRCh371176,998,499 - 176,998,581 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361175,265,121 - 175,265,203 (-)NCBINCBI36Build 36hg18NCBI36
Celera1150,108,504 - 150,108,586 (-)NCBICelera
Cytogenetic Map1q25.2NCBI
HuRef1148,224,993 - 148,225,075 (-)NCBIHuRef
CHM1_11178,422,539 - 178,422,621 (-)NCBICHM1_1
T2T-CHM13v2.01176,384,002 - 176,384,084 (-)NCBIT2T-CHM13v2.0
Mir488
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391158,333,195 - 158,333,303 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1158,333,195 - 158,333,303 (+)EnsemblGRCm39 Ensembl
GRCm381158,505,625 - 158,505,733 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1158,505,625 - 158,505,733 (+)EnsemblGRCm38mm10GRCm38
MGSCv371160,435,756 - 160,435,864 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1160,900,459 - 160,900,567 (+)NCBICelera
Cytogenetic Map1H1NCBI
cM Map168.46NCBI
Mir488
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81373,216,541 - 73,216,619 (+)NCBIGRCr8
mRatBN7.21370,683,064 - 70,683,142 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1370,683,064 - 70,683,142 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1373,260,030 - 73,260,108 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01374,560,257 - 74,560,335 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01371,819,607 - 71,819,685 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01376,198,593 - 76,198,671 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1376,198,593 - 76,198,671 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01381,112,954 - 81,113,032 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1370,496,620 - 70,496,698 (+)NCBICelera
Cytogenetic Map13q22NCBI

Variants

.
Variants in MIR488
1 total Variants

Expression

RNA-SEQ Expression

reproductive system
5

Sequence


Ensembl Acc Id: ENSCAFT00000034890
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl722,597,953 - 22,598,035 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845014925
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl722,344,624 - 22,344,706 (+)Ensembl
RefSeq Acc Id: NR_049492
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1722,597,953 - 22,598,035 (+)NCBI
Dog10K_Boxer_Tasha722,122,143 - 22,122,225 (+)NCBI
ROS_Cfam_1.0722,344,624 - 22,344,706 (+)NCBI
UMICH_Zoey_3.1722,250,245 - 22,250,327 (+)NCBI
UNSW_CanFamBas_1.0722,350,320 - 22,350,402 (+)NCBI
UU_Cfam_GSD_1.0722,493,251 - 22,493,333 (+)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000022783 Ensembl
  ENSCAFG00845008500 Ensembl, ENTREZGENE
Ensembl Transcript ENSCAFT00845014925 ENTREZGENE
miRBase MI0010402 ENTREZGENE
NCBI Gene MIR488 ENTREZGENE
RNAcentral URS00002A36ED RNACentral
  URS00002CC311 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 MIR488  microRNA mir-488    microRNA 488  Symbol and/or name change 5135510 APPROVED