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Gene: SCN2B (sodium voltage-gated channel beta subunit 2) Canis lupus familiaris

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Symbol:

SCN2B

Name:

sodium voltage-gated channel beta subunit 2

RGD ID:

12210041

Description:

ENCODES a protein that exhibits voltage-gated sodium channel activity (ortholog); INVOLVED IN cardiac conduction (ortholog); gene expression (ortholog); nervous system development (ortholog); ASSOCIATED WITH CD3epsilon deficiency (ortholog); chromosome 11 partial duplication syndrome (ortholog); dilated cardiomyopathy (ortholog); FOUND IN axon initial segment (ortholog); node of Ranvier (ortholog); T-tubule (ortholog)

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

cardiomyocyte sodium channel beta-2 subunit; sodium channel regulatory subunit beta-2; sodium channel subunit beta-2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	15,514,760 - 15,534,179 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	15,521,481 - 15,534,179 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	15,572,346 - 15,585,043 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	15,463,692 - 15,476,337 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	15,456,869 - 15,476,337 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	15,601,775 - 15,614,477 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	15,505,329 - 15,518,028 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	15,546,638 - 15,559,352 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

CD3epsilon deficiency (ISO)

chromosome 11 partial duplication syndrome (ISO)

dilated cardiomyopathy (ISO)

Dwarfism (ISO)

Experimental Seizures (ISO)

Familial Atrial Fibrillation 14 (ISO)

glycogen storage disease Ib (ISO)

immunodeficiency 17 (ISO)

immunodeficiency 18 (ISO)

immunodeficiency 19 (ISO)

inflammatory bowel disease 28 (ISO)

intellectual disability (ISO)

isolated microphthalmia 5 (ISO)

long QT syndrome 10 (ISO)

otitis media (ISO)

RASopathy (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cardiac conduction (IBA,IEA,ISO)

cardiac muscle cell action potential involved in contraction (IBA,IEA)

cardiac muscle contraction (IEA)

gene expression (IEA,ISO)

membrane depolarization during action potential (IEA)

membrane depolarization during cardiac muscle cell action potential (IBA,IEA)

membrane repolarization during ventricular cardiac muscle cell action potential (IEA)

nervous system development (ISO)

positive regulation of sodium ion transport (IEA)

regulation of atrial cardiac muscle cell membrane depolarization (IEA)

regulation of heart rate by cardiac conduction (IEA)

response to heat (IEA,ISO)

response to pyrethroid (ISO)

sodium ion transport (IEA,ISO)

Cellular Component

axon (IEA)

axon initial segment (ISO)

cell projection (IEA)

membrane (IEA)

node of Ranvier (ISO)

plasma membrane (IBA,IEA)

T-tubule (IEA,ISO)

voltage-gated sodium channel complex (IBA,IEA,ISS)

Molecular Function

protein binding (ISO)

sodium channel regulator activity (IBA,IEA)

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization (IEA)

voltage-gated sodium channel activity (ISO)

voltage-gated sodium channel activity involved in cardiac muscle cell action potential (IEA)

References

Additional References at PubMed

PMID:21705762	PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

SCN2B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	15,514,760 - 15,534,179 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	15,521,481 - 15,534,179 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	15,572,346 - 15,585,043 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	15,463,692 - 15,476,337 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	15,456,869 - 15,476,337 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	15,601,775 - 15,614,477 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	15,505,329 - 15,518,028 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	15,546,638 - 15,559,352 (+)	NCBI		UU_Cfam_GSD_1.0

SCN2B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	118,162,806 - 118,176,639 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	118,162,806 - 118,176,639 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	118,033,521 - 118,047,354 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	117,538,729 - 117,552,546 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	117,538,728 - 117,552,546	NCBI
Celera	11	115,191,374 - 115,205,190 (-)	NCBI		Celera
Cytogenetic Map	11	q23.3	NCBI
HuRef	11	113,967,183 - 113,980,997 (-)	NCBI		HuRef
CHM1_1	11	117,919,350 - 117,933,166 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	118,179,198 - 118,193,026 (-)	NCBI		T2T-CHM13v2.0

Scn2b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	45,029,174 - 45,041,368 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	45,029,080 - 45,041,368 (+)	Ensembl		GRCm39 Ensembl
GRCm38	9	45,117,876 - 45,130,070 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	45,117,782 - 45,130,070 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	44,925,959 - 44,938,153 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	44,868,876 - 44,881,065 (+)	NCBI		MGSCv36	mm8
Celera	9	42,393,438 - 42,405,653 (+)	NCBI		Celera
Cytogenetic Map	9	A5.2	NCBI
cM Map	9	24.84	NCBI

Scn2b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	54,322,383 - 54,334,519 (+)	NCBI		GRCr8
mRatBN7.2	8	45,425,629 - 45,437,765 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	45,425,629 - 45,437,765 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	50,921,042 - 50,933,209 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	49,199,783 - 49,211,951 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	47,070,360 - 47,082,527 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	49,419,003 - 49,431,110 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	49,418,965 - 49,427,689 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	48,045,397 - 48,057,559 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	48,068,843 - 48,078,632 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	48,077,608 - 48,087,398 (+)	NCBI
Celera	8	45,010,175 - 45,018,724 (+)	NCBI		Celera
Cytogenetic Map	8	q22	NCBI

Scn2b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955412	19,340,947 - 19,354,062 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955412	19,341,008 - 19,353,563 (-)	NCBI	ChiLan1.0	ChiLan1.0

SCN2B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	118,863,121 - 118,876,923 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	119,968,076 - 119,981,881 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	112,996,609 - 113,010,412 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	116,928,676 - 116,942,506 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	116,928,676 - 116,942,500 (-)	Ensembl	panpan1.1		panPan2

Scn2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	100,340,752 - 100,353,142 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936542	3,261,533 - 3,274,623 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936542	3,262,161 - 3,274,545 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SCN2B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	45,484,998 - 45,498,465 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	45,484,994 - 45,502,578 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	50,526,026 - 50,543,574 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SCN2B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	109,538,694 - 109,552,745 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	109,538,652 - 109,552,740 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666043	16,476,980 - 16,490,889 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Scn2b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624784	13,580,313 - 13,593,169 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624784	13,580,427 - 13,593,055 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in SCN2B
251 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001168459	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022418001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022418002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022418003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022418004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038664052	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038664054	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038664055	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000059	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000089	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000371	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000045172 ⟹ ENSCAFP00000042471

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	5	15,521,481 - 15,534,179 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845004871 ⟹ ENSCAFP00845003895

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	5	15,456,869 - 15,476,337 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845004884 ⟹ ENSCAFP00845003904

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	5	15,463,633 - 15,476,337 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845004895 ⟹ ENSCAFP00845003911

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	5	15,466,753 - 15,476,337 (+)	Ensembl

RefSeq Acc Id:

NM_001168459 ⟹ NP_001161931

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	5	15,521,481 - 15,534,179 (+)	NCBI
Dog10K_Boxer_Tasha	5	15,572,346 - 15,585,043 (+)	NCBI
ROS_Cfam_1.0	5	15,463,692 - 15,476,337 (+)	NCBI
UMICH_Zoey_3.1	5	15,601,775 - 15,614,477 (+)	NCBI
UNSW_CanFamBas_1.0	5	15,505,329 - 15,518,028 (+)	NCBI
UU_Cfam_GSD_1.0	5	15,546,638 - 15,559,352 (+)	NCBI

Sequence:

show sequence

AAAGCTTCCTTAATGTTGTATGTGTCTTTGAAGTACATCTGTGCATTTTTTTTTTTAGCATCTA
ACCATTCCTCCCTTGTAGCCCTCGGCCCCTCAAATCACCCTCTCCCCCATCCCACCCGACTAAC
ATCTCAGTCTCTGAAAATGCACAGAGATGCCTGGCTACCTCGCCCTGCCTTCAGTCTCACGGGG
CTCAGTCTCTTTTTCTCTTTGGTGCCACCAGGGCGGAGCATGGAGGTCACAGTACCTACCACCC
TCAACGTCCTCAATGGCTCTAATGCCCGTCTGCCCTGTACCTTCAACTCCTGCTATACAGTGAA
CCACAAACAGTTCTCCCTAAACTGGACTTACCAGGAGTGTAGTAACTGCTCGGAGGAGATGTTC
CTCCAGTTCCGCATGAAGATCATCAACCTGAAGCTGGAGCGGTTCCGGGACCGCGTGGAGTTCT
CGGGGAACCCCAGCAAGTATGATGTGTCCGTGACGCTGAGAAACGTGCAGCTCGAAGATGTGGG
CACCTACAACTGCTACATCATGAACCCGCCCGACCGCCACCGCGGCCACGGCAGGATCCAACTG
CAGGTCCTCATGGAAGAGCCCCCTGAGCGGGACTCCACGGTGGCCGTGATCGTGGGCGCCTCCG
TGGGCGGCTTCCTGGCGGTGGTCATCCTGGTGCTGATGGTAGTAAAGTGTGTGAGGAGGAAAAA
AGAGCAGAAACTGAGCACCGACGACCTGAAGACAGACGAGGAGGGCAAGACTGATGGAGAGGGA
AACGCGGACGACGGCCCCAAGTAACAGGCCCCGCAGCCCCCCTCGTGTCCTGTCGCCCTCCCAC
CCTCCGCCCCGCACACTGTGCCCCTGCCTGCCCTCTCTTGGTGTGCTTCTCCTGAACCGGGGTC
CCAGTGCCCACCTGGGGCCCCCCGAACCCCTCACGTCGTGTCCCCCACCCTGCACCAAGAGTGA
CCCACCTCTCTTTCATTTGGGAAACCTGCCGTGGCGCGTGGGATGTGTGGGCCCCCAGGGGAGG
GACAAGTGGGCTCTGACTGCCGGCCCCTGAGTGGAGGCAGGAGGCCTGTGAGAGGGTCCCAGGA
AGACACGGGGCGCCCACCCGGCCCTGTCTGTGCACTGGTCTGGTGGGCCTCAGGGAGCACCTGC
GGGCGGCGGAGGGGCTCTCCTGCGCTGCCTCCCGGAGCCGCTCCAGCCCTGGCGGCCCTGTCAG
GCTGGGGGTGCTGGTGGGTTCCTATAACTTGGGTGGCGGGCGTGTCAGAGGGACGACTGTGTTT
CCTGGACATTGCAGGGAAGCTGGGGCCGGAGGGCAGGTGGAGAGGAGCCTAAGCCCGGGGACCC
ATGCTCTTACCCCCTCTCCATCAGTAGCTGCTACCACAGAAGCCTTGGGGGGTTTCTGTGGGCT
GCTAATCTCTTGGGATTTGGAGGGGGGAGCACTGTGCTGAAGAGTTGCCAAGCTGGGCGGTGGG
GAGGTTGTATCATTTTTCACCATAGCCATAAAGAACAGGAGACAAAATTCAAAGTCAGCTAAGA
TCTGAAGGGGTGGGGGTGGCACTGTAAGATGGAGTTGGTCGCAGGCTGGCTTCTCCAACCTGGT
GACCTCCCTGTCAGCTGAGTGTGGGGCTGGGGAGGCGCCACGCCACGCGGAGCAGTGGGTGTGG
GGAGTCGGGGCTTCCTCTGGGCCCTTGTGTTTTGTGTTGGAACTTTCCCAGGTACCATCAGCAG
GGCTTTTAGTTGGCTTTTGGGTAGAGACTGGGAAGGGAGCACCCCGAGGGGAGAGTGAGGGGAG
CCTTGGAGCTTCTGAGACGCTATGGGCATGTTATACCCTCCCTGCCCCAGGGACTCCCTCTGTG
GGGAGGAAGGTAGCATTTATGGAGAGCCAACTTTCACTGCCATTTTACTCACATTAAGAGGGAA
TCATTTAAGCCTCAAGAGAGGGAGAGAACCAGAGAGAAACTGCTGACGTGAACACTACCTTGGA
AGATCCTCAGGGATCAACCAGGCAAGTCCCACTACAGATGGGGAAACGGGTTCAAAATGACAGA
GACCAAGGGTCCTGCTATCCCCTCCTCTGGCTCCTCAGTCTCCAGTTTGAATCAACAGAGCCAT
AGTTTTCCTCTCCATAAGGAGGGGAGGGGACGGAAGGGAGGGCTGCTCCTCTCCCAGGCCGGTG
GGAATGGAGGGATGGAGCAGGAGGGCAGAGCTGCTGGCAAGGCCCTGCCCCTGCCCCACACTGA
CTGACCTTCAGCCCTTCCCTGGCCTTTCCAGGAGCTCAGACCCCACCCAGGTTCTGGGAGTCAG
CGTCCTGGGCAGGAACCGGTCTGGGGAAAGTGAGTGGAGACAGGACTGTGACAGTCTCAGGGAC
AGTCTCAGGGACCATTCTCTGCCTCTGCCCATCAGATGGCCAGTTTGGGGAGAGAACAGTAGCA
TCCATGAGGTTCAGTTTAATTCACTTCAATTCGACATCCATTTATTGAGCATCTCCTGTGTGCC
AGGCACTGTGCCAGGTGCCAGGGATGCACACAAAGCCATAACACAGTTGGAAGCTGCCAGGTCA
GCACTGTGGGGACCAAGATTAATTTTTTTTGGTGCATCTAATTCCACCTCTGCAGCCACTGCTT
CCAGGGCTGGAGTTGGAGAAGGAAGACAGTCCCAAATCTGGGCCCTGGGAAGGGAAGAAAGGCA
GGAAGGCGGGTAGTGGTGGTGGTGGTGGTGGTGGGAGATTCAACAGGGAACAGGGTGACAGGCC
AGGCAGAGTGGGCACAGAGTGGGGGACGGACAGCCTGGGTGACAGCTCCGGGGTGGGGGGAGTC
CAGCTCAGTACCTAACTGCCAATCAACACACTGCCAATGGGGGTGGGCTAAGCCACCAGGATGC
CTGGGGCAGGAGGACACAGCCATCCTTGGAGCCAACCAGCCACGAGGGGAGCGATGGGCAGCTG
AGACCAAGGGCGGTTGCGATACGCAGAAGCAGCCCGCAGATTTCTCCTCGCAGCCACCTCTCAA
GTATTCTCTTCTCCCAGGATGAGTGAGGATCTGTGCTGATGCGGGGCACGCCTCACATTTAGGG
AACTTTTTGCGCGATTCCCTAGGTTTATTCTAAGAAATCCCAACTCCCCATCAAGAAGCTCCAG
ACTTCTGGGCTCCTTCCTTCCAACGCTCTGGCCCAGGGTGGGGGGCCCTCCCGAGCTGCCCCAC
TCTCTTGTGCACTTTCTCCTGCAGCCTCTTTGAATCTCTTCGGGAGGAGGTCTCCTAGAGCTGC
CTCCCCCAGGGCCGTGAGGTTGGGAACAAGATGGGGCTTCTGTGCATAGAGGTGGGAAACCCGT
GACATGTTTCCACAGCAGCCATTTCTCTACCCTGCTTTCTAGTTTATACCAGCAAGCCGCTCCT
CTCCCTGCACTGTGGGTTCACGTCCCACTTTTCCCACTTGCGGCTGCATGTTCCCATCACTGCG
CTCTCCTGGGTCCAGTCTGCTGGTTTTCCCAACAGCCCCTGCCTCTCCTGCTGTCTTAGAACTC
CCTGTCTGTCTCTTCCTCCTAATTTAAGGGCCACTGTAAGGAGATGGGCTGGCCAACCCATGCG
ATTGAGCTTATAAGAGCAGAGTGCAATTTTTCAGGACTGAAATGCCTTGAGGTGCCTTGAAACT
GGCTTTGAAAACGGCTGTCTGCCCCTTAGCGATGGACTAATCACAGTTATTCCCAATCTATAAA
AAGGAAAAGCCGACTGGTTCCATATTTCTCCCTGGAGGTCCCCTTGGGGAAGTTGGGCTGGTAT
TTACAAGGTCAGGTTAAAGCAGATGGACGATGGAAAATACTGGCCAGGTCCCAAAAGACAGTCC
CAGGCCATAGGAATGGCGTGATGCAGTTGGAATGAGTGATGAATCAAGAAATTTTCCTTGCAAC
TCATCTTAAGGATAGACAGCCTGTGTCTCTTGCTGTGCCTCGTGCTAATGTCTTCCTTTATTGA
AGCTTGCTGATGCATTTGTACATAGTCTATATATAGGTATAGATATATTATATATACAAATATA
AAACATCTCACTACATCCACTCCAAAAGTTACACTGGGTGTTGAGGGAAAAACCATCATTTCTC
AGTGTTTTGAGTTGATTCACCAAAGGCAAATTATGGAATGTTCTTACTGCTTTTTGTGCACTTG
GAGGAGAAAACTCAGCTACTTATGCACTTTCTGGGTTTTCTGTGCTGCAGGGTGGTTGGAGGGG
GTGGTGGGGAGAACAACTTCGATGGTCCTCTGTGACCCAGCTGCTGTGATGTGTCTGCTTTGGG
GAGCAGGCTGTGTTTTCTTTGCAGTTTGTTGTATTGCTTGGATCTATTGGCTACAATAAACAGA
TCATCTCCCCCGAA

hide sequence

RefSeq Acc Id:

XM_038664052 ⟹ XP_038519980

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	5	15,466,533 - 15,476,337 (+)	NCBI

RefSeq Acc Id:

XM_038664054 ⟹ XP_038519982

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	5	15,466,782 - 15,476,337 (+)	NCBI

RefSeq Acc Id:

XM_038664055 ⟹ XP_038519983

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	5	15,464,889 - 15,476,337 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001161931	(Get FASTA)	NCBI Sequence Viewer
	XP_038519980	(Get FASTA)	NCBI Sequence Viewer
	XP_038519982	(Get FASTA)	NCBI Sequence Viewer
	XP_038519983	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000042471.1
	ENSCAFP00000071464.1
	ENSCAFP00000071794.1
	ENSCAFP00030014243.1
	ENSCAFP00040002233.1
	ENSCAFP00845003895
	ENSCAFP00845003895.1
	ENSCAFP00845003904
	ENSCAFP00845003904.1
	ENSCAFP00845003911
	ENSCAFP00845003911.1
GenBank Protein	Q864L3	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001161931 ⟸ NM_001168459
- Peptide Label:	precursor
- UniProtKB:	Q864L3 (UniProtKB/Swiss-Prot), A0A8C0JL81 (UniProtKB/TrEMBL), A0A8C0MN25 (UniProtKB/TrEMBL)
- Sequence:	show sequence MHRDAWLPRPAFSLTGLSLFFSLVPPGRSMEVTVPTTLNVLNGSNARLPCTFNSCYTVNHKQFS LNWTYQECSNCSEEMFLQFRMKIINLKLERFRDRVEFSGNPSKYDVSVTLRNVQLEDVGTYNCY IMNPPDRHRGHGRIQLQVLMEEPPERDSTVAVIVGASVGGFLAVVILVLMVVKCVRRKKEQKLS TDDLKTDEEGKTDGEGNADDGPK hide sequence

Ensembl Acc Id:

ENSCAFP00000042471 ⟸ ENSCAFT00000045172

RefSeq Acc Id:	XP_038519983 ⟸ XM_038664055
- Peptide Label:	isoform X3
- UniProtKB:	Q864L3 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038519980 ⟸ XM_038664052
- Peptide Label:	isoform X1
- UniProtKB:	Q864L3 (UniProtKB/Swiss-Prot), A0A8I3MN22 (UniProtKB/TrEMBL), A0A8P0PLU4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038519982 ⟸ XM_038664054
- Peptide Label:	isoform X2
- UniProtKB:	Q864L3 (UniProtKB/Swiss-Prot)

Ensembl Acc Id:

ENSCAFP00845003904 ⟸ ENSCAFT00845004884

Ensembl Acc Id:

ENSCAFP00845003895 ⟸ ENSCAFT00845004871

Ensembl Acc Id:

ENSCAFP00845003911 ⟸ ENSCAFT00845004895

Protein Domains

Ig-like Ig-like C2-type

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000029322	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030008827	UniProtKB/TrEMBL
	ENSCAFG00040001373	UniProtKB/TrEMBL
	ENSCAFG00845002736	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000045172.3	UniProtKB/TrEMBL
	ENSCAFT00000094414.1	UniProtKB/TrEMBL
	ENSCAFT00000097982.1	UniProtKB/TrEMBL
	ENSCAFT00030016313.1	UniProtKB/TrEMBL
	ENSCAFT00040002597.1	UniProtKB/TrEMBL
	ENSCAFT00845004871	ENTREZGENE
	ENSCAFT00845004871.1	UniProtKB/TrEMBL
	ENSCAFT00845004884	ENTREZGENE
	ENSCAFT00845004884.1	UniProtKB/TrEMBL
	ENSCAFT00845004895	ENTREZGENE
	ENSCAFT00845004895.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Ig-like_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_sub	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_V-set	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Myelin_P0-rel	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	cfa:403485	UniProtKB/TrEMBL
NCBI Gene	SCN2B	ENTREZGENE
PANTHER	PTHR13869	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR13869:SF3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	V-set	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS	MYELINP0	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	IG_LIKE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	IGv	UniProtKB/TrEMBL
	SM00409	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF48726	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8C0JL81	ENTREZGENE
	A0A8C0MN25	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3MME7_CANLF	UniProtKB/TrEMBL
	A0A8I3MN22	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3RSE8_CANLF	UniProtKB/TrEMBL
	A0A8P0NT77_CANLF	UniProtKB/TrEMBL
	A0A8P0PLU4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0TQ50_CANLF	UniProtKB/TrEMBL
	Q864L3	ENTREZGENE, UniProtKB/Swiss-Prot
VGNC ID	VGNC:45917	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM