Scn2b (sodium voltage-gated channel beta subunit 2) - Rat Genome Database

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Gene: Scn2b (sodium voltage-gated channel beta subunit 2) Ictidomys tridecemlineatus
Analyze
Symbol: Scn2b
Name: sodium voltage-gated channel beta subunit 2
RGD ID: 12605254
Description: ENCODES a protein that exhibits voltage-gated sodium channel activity (ortholog); INVOLVED IN cardiac conduction (ortholog); gene expression (ortholog); nervous system development (ortholog); ASSOCIATED WITH CD3epsilon deficiency (ortholog); chromosome 11 partial duplication syndrome (ortholog); dilated cardiomyopathy (ortholog); FOUND IN axon initial segment (ortholog); node of Ranvier (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sodium channel subunit beta-2; sodium channel, voltage-gated, type II, beta subunit
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947100,340,752 - 100,353,142 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365423,261,533 - 3,274,623 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365423,262,161 - 3,274,545 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Scn2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947100,340,752 - 100,353,142 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365423,261,533 - 3,274,623 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365423,262,161 - 3,274,545 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SCN2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811118,162,806 - 118,176,639 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11118,162,806 - 118,176,639 (-)EnsemblGRCh38hg38GRCh38
GRCh3711118,033,521 - 118,047,354 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611117,538,729 - 117,552,546 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411117,538,728 - 117,552,546NCBI
Celera11115,191,374 - 115,205,190 (-)NCBICelera
Cytogenetic Map11q23.3NCBI
HuRef11113,967,183 - 113,980,997 (-)NCBIHuRef
CHM1_111117,919,350 - 117,933,166 (-)NCBICHM1_1
T2T-CHM13v2.011118,179,198 - 118,193,026 (-)NCBIT2T-CHM13v2.0
Scn2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39945,029,174 - 45,041,368 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl945,029,080 - 45,041,368 (+)EnsemblGRCm39 Ensembl
GRCm38945,117,876 - 45,130,070 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl945,117,782 - 45,130,070 (+)EnsemblGRCm38mm10GRCm38
MGSCv37944,925,959 - 44,938,153 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36944,868,876 - 44,881,065 (+)NCBIMGSCv36mm8
Celera942,393,438 - 42,405,653 (+)NCBICelera
Cytogenetic Map9A5.2NCBI
cM Map924.84NCBI
Scn2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8854,322,383 - 54,334,519 (+)NCBIGRCr8
mRatBN7.2845,425,629 - 45,437,765 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl845,425,629 - 45,437,765 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx850,921,042 - 50,933,209 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0849,199,783 - 49,211,951 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0847,070,360 - 47,082,527 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0849,419,003 - 49,431,110 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl849,418,965 - 49,427,689 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0848,045,397 - 48,057,559 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4848,068,843 - 48,078,632 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1848,077,608 - 48,087,398 (+)NCBI
Celera845,010,175 - 45,018,724 (+)NCBICelera
Cytogenetic Map8q22NCBI
Scn2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541219,340,947 - 19,354,062 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541219,341,008 - 19,353,563 (-)NCBIChiLan1.0ChiLan1.0
SCN2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29118,863,121 - 118,876,923 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111119,968,076 - 119,981,881 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011112,996,609 - 113,010,412 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111116,928,676 - 116,942,506 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11116,928,676 - 116,942,500 (-)Ensemblpanpan1.1panPan2
SCN2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1515,514,760 - 15,534,179 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl515,521,481 - 15,534,179 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha515,572,346 - 15,585,043 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0515,463,692 - 15,476,337 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl515,456,869 - 15,476,337 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1515,601,775 - 15,614,477 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0515,505,329 - 15,518,028 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0515,546,638 - 15,559,352 (+)NCBIUU_Cfam_GSD_1.0
SCN2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl945,484,998 - 45,498,465 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1945,484,994 - 45,502,578 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2950,526,026 - 50,543,574 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SCN2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11109,538,694 - 109,552,745 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1109,538,652 - 109,552,740 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604316,476,980 - 16,490,889 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Scn2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478413,580,313 - 13,593,169 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478413,580,427 - 13,593,055 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005328319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSSTOT00000020869   ⟹   ENSSTOP00000015370
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365423,261,533 - 3,274,623 (-)Ensembl
RefSeq Acc Id: XM_005328319   ⟹   XP_005328376
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947100,340,752 - 100,353,142 (-)NCBI
SpeTri2.0NW_0049365423,262,161 - 3,274,545 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005328376 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000015370.1
GenBank Protein KAG3286637 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005328376   ⟸   XM_005328319
- UniProtKB: I3MTC5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSTOP00000015370   ⟸   ENSSTOT00000020869
Protein Domains
Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000021064 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000020869.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
  Myelin_P0-rel UniProtKB/TrEMBL
NCBI Gene Scn2b ENTREZGENE
PANTHER PTHR13869 UniProtKB/TrEMBL
  PTHR13869:SF3 UniProtKB/TrEMBL
Pfam V-set UniProtKB/TrEMBL
PRINTS MYELINP0 UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART IGv UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt I3MTC5 ENTREZGENE, UniProtKB/TrEMBL