PPIF (peptidylprolyl isomerase F) - Rat Genome Database

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Gene: PPIF (peptidylprolyl isomerase F) Canis lupus familiaris
Analyze
Symbol: PPIF
Name: peptidylprolyl isomerase F
RGD ID: 12180717
Description: ENCODES a protein that exhibits cyclosporin A binding (ortholog); peptide binding (ortholog); peptidyl-prolyl cis-trans isomerase activity (ortholog); INVOLVED IN apoptotic mitochondrial changes (ortholog); apoptotic process (ortholog); mitochondrial depolarization (ortholog); ASSOCIATED WITH COVID-19 (ortholog); intestinal disease (ortholog); Ulcer (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrial matrix (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: peptidyl-prolyl cis-trans isomerase F, mitochondrial; peptidylprolyl isomerase F (cyclophilin F)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1429,074,806 - 29,080,487 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha429,197,719 - 29,204,179 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0429,374,690 - 29,381,134 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl429,374,690 - 29,380,211 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1429,245,431 - 29,251,855 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0429,447,801 - 29,454,224 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0429,801,525 - 29,807,938 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
COVID-19  (ISO)
intestinal disease  (ISO)
Ulcer  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PPIF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1429,074,806 - 29,080,487 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha429,197,719 - 29,204,179 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0429,374,690 - 29,381,134 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl429,374,690 - 29,380,211 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1429,245,431 - 29,251,855 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0429,447,801 - 29,454,224 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0429,801,525 - 29,807,938 (+)NCBIUU_Cfam_GSD_1.0
PPIF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381079,347,469 - 79,355,334 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1079,347,469 - 79,355,334 (+)EnsemblGRCh38hg38GRCh38
GRCh371081,107,225 - 81,115,090 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361080,777,226 - 80,785,096 (+)NCBINCBI36Build 36hg18NCBI36
Build 341080,777,225 - 80,785,093NCBI
Celera1074,393,355 - 74,401,225 (+)NCBICelera
Cytogenetic Map10q22.3NCBI
HuRef1075,101,849 - 75,109,719 (+)NCBIHuRef
CHM1_11081,390,186 - 81,398,056 (+)NCBICHM1_1
T2T-CHM13v2.01080,216,813 - 80,224,678 (+)NCBIT2T-CHM13v2.0
Ppif
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391425,693,998 - 25,700,892 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1425,694,578 - 25,700,892 (+)EnsemblGRCm39 Ensembl
GRCm381425,693,574 - 25,700,468 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1425,694,154 - 25,700,468 (+)EnsemblGRCm38mm10GRCm38
MGSCv371426,513,656 - 26,519,954 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361424,527,354 - 24,533,652 (+)NCBIMGSCv36mm8
Celera1422,018,432 - 22,024,722 (+)NCBICelera
Cytogenetic Map14A3NCBI
cM Map1415.06NCBI
Ppif
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8161,264,001 - 1,270,722 (+)NCBIGRCr8
mRatBN7.2161,257,197 - 1,263,919 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl161,257,106 - 1,263,913 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx161,263,511 - 1,270,232 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0162,409,364 - 2,416,086 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0161,270,127 - 1,276,849 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0161,979,191 - 1,985,912 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl161,979,191 - 1,985,908 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0161,955,730 - 1,962,451 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4161,292,835 - 1,299,556 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1161,292,834 - 1,299,555 (+)NCBI
Celera161,234,115 - 1,240,836 (+)NCBICelera
Cytogenetic Map16p16NCBI
Ppif
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543713,295,663 - 13,302,175 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543713,295,766 - 13,301,918 (-)NCBIChiLan1.0ChiLan1.0
PPIF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2891,486,543 - 91,496,372 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11091,491,867 - 91,501,079 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01075,860,197 - 75,868,098 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11078,521,996 - 78,530,211 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1078,521,642 - 78,530,202 (+)Ensemblpanpan1.1panPan2
Ppif
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721351,911,849 - 51,918,430 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936521404,544 - 411,539 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936521404,574 - 411,381 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPIF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1481,667,672 - 81,689,495 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11481,674,671 - 81,681,977 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21488,334,121 - 88,341,247 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PPIF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1952,109,865 - 52,117,703 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl952,109,272 - 52,117,483 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604812,454,125 - 12,466,531 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppif
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475412,336,427 - 12,342,687 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475412,336,474 - 12,342,687 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PPIF
121 total Variants

Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCAFT00845025821   ⟹   ENSCAFP00845020344
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl429,374,690 - 29,380,211 (+)Ensembl
RefSeq Acc Id: XM_038473398   ⟹   XP_038329326
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1429,245,431 - 29,251,855 (+)NCBI
RefSeq Acc Id: XM_038492660   ⟹   XP_038348588
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha429,197,719 - 29,204,179 (+)NCBI
RefSeq Acc Id: XM_038534466   ⟹   XP_038390394
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0429,801,525 - 29,807,938 (+)NCBI
RefSeq Acc Id: XM_038598793   ⟹   XP_038454721
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0429,447,801 - 29,454,224 (+)NCBI
RefSeq Acc Id: XM_038663064   ⟹   XP_038518992
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0429,374,690 - 29,381,134 (+)NCBI
RefSeq Acc Id: XP_038329326   ⟸   XM_038473398
RefSeq Acc Id: XP_038454721   ⟸   XM_038598793
RefSeq Acc Id: XP_038518992   ⟸   XM_038663064
- UniProtKB: A0A8C0M3B9 (UniProtKB/TrEMBL),   A0A8I3NJM2 (UniProtKB/TrEMBL),   A0A8C0KNC8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038348588   ⟸   XM_038492660
- UniProtKB: A0A8C0M3B9 (UniProtKB/TrEMBL),   A0A8I3NJM2 (UniProtKB/TrEMBL),   A0A8C0KNC8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038390394   ⟸   XM_038534466
- UniProtKB: A0A8C0KNC8 (UniProtKB/TrEMBL),   A0A8C0M3B9 (UniProtKB/TrEMBL),   A0A8I3NJM2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845020344   ⟸   ENSCAFT00845025821
Protein Domains
PPIase cyclophilin-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000032043 UniProtKB/TrEMBL
  ENSCAFG00030002047 UniProtKB/TrEMBL
  ENSCAFG00040025094 UniProtKB/TrEMBL
  ENSCAFG00845014432 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000042835.3 UniProtKB/TrEMBL
  ENSCAFT00030003738.1 UniProtKB/TrEMBL
  ENSCAFT00040046797.1 UniProtKB/TrEMBL
  ENSCAFT00845025821 ENTREZGENE
  ENSCAFT00845025821.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.100.10 UniProtKB/TrEMBL
InterPro Cyclophilin-like_dom_sf UniProtKB/TrEMBL
  Cyclophilin-type_PPIase_CS UniProtKB/TrEMBL
  Cyclophilin-type_PPIase_dom UniProtKB/TrEMBL
NCBI Gene PPIF ENTREZGENE
PANTHER PEPTIDYL-PROLYL CIS-TRANS ISOMERASE UniProtKB/TrEMBL
  PEPTIDYL-PROLYL CIS-TRANS ISOMERASE F, MITOCHONDRIAL UniProtKB/TrEMBL
Pfam Pro_isomerase UniProtKB/TrEMBL
PRINTS CSAPPISMRASE UniProtKB/TrEMBL
PROSITE CSA_PPIASE_1 UniProtKB/TrEMBL
  CSA_PPIASE_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF50891 UniProtKB/TrEMBL
UniProt A0A8C0KNC8 ENTREZGENE
  A0A8C0M3B9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NJM2 ENTREZGENE, UniProtKB/TrEMBL